Experiment: L-Histidine (N)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_328 and PfGW456L13_329 overlap by 4 nucleotides PfGW456L13_329 and PfGW456L13_330 are separated by 107 nucleotides PfGW456L13_330 and PfGW456L13_331 are separated by 114 nucleotides PfGW456L13_331 and PfGW456L13_332 are separated by 30 nucleotides
PfGW456L13_328 - Conserved hypothetical protein (perhaps related to histidine degradation), at 383,688 to 384,257
_328
PfGW456L13_329 - Histidine utilization repressor, at 384,254 to 385,003
_329
PfGW456L13_330 - Formiminoglutamic iminohydrolase (EC 3.5.3.13) <small>(from data)</small>, at 385,111 to 386,475
_330
PfGW456L13_331 - Outer membrane lipoprotein Blc, at 386,590 to 387,159
_331
PfGW456L13_332 - Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1), at 387,190 to 387,444
_332
Position (kb) 385
386
387 Strain fitness (log2 ratio) -4
-3
-2
-1
0
1
2
3 at 384.237 kb on + strand at 384.238 kb on - strand at 384.247 kb on - strand at 384.247 kb on - strand at 384.259 kb on + strand at 384.259 kb on + strand at 384.259 kb on + strand at 384.259 kb on + strand at 384.260 kb on - strand at 384.260 kb on - strand at 384.465 kb on + strand, within PfGW456L13_329 at 384.465 kb on + strand, within PfGW456L13_329 at 384.504 kb on + strand, within PfGW456L13_329 at 384.725 kb on + strand, within PfGW456L13_329 at 384.725 kb on + strand, within PfGW456L13_329 at 384.940 kb on - strand at 385.008 kb on - strand at 385.008 kb on - strand at 385.022 kb on + strand at 385.022 kb on + strand at 385.022 kb on + strand at 385.025 kb on + strand at 385.025 kb on + strand at 385.025 kb on + strand at 385.025 kb on + strand at 385.025 kb on + strand at 385.025 kb on + strand at 385.026 kb on - strand at 385.026 kb on - strand at 385.026 kb on - strand at 385.026 kb on - strand at 385.026 kb on - strand at 385.036 kb on - strand at 385.071 kb on + strand at 385.071 kb on + strand at 385.072 kb on - strand at 385.072 kb on - strand at 385.072 kb on - strand at 385.073 kb on + strand at 385.073 kb on + strand at 385.073 kb on + strand at 385.073 kb on + strand at 385.074 kb on - strand at 385.074 kb on - strand at 385.074 kb on - strand at 385.074 kb on - strand at 385.074 kb on - strand at 385.074 kb on - strand at 385.074 kb on - strand at 385.077 kb on + strand at 385.077 kb on + strand at 385.077 kb on + strand at 385.078 kb on - strand at 385.078 kb on - strand at 385.078 kb on - strand at 385.078 kb on - strand at 385.078 kb on - strand at 385.146 kb on + strand at 385.147 kb on - strand at 385.166 kb on + strand at 385.166 kb on + strand at 385.166 kb on + strand at 385.166 kb on + strand at 385.166 kb on + strand at 385.166 kb on + strand at 385.166 kb on + strand at 385.166 kb on + strand at 385.167 kb on - strand at 385.167 kb on - strand at 385.203 kb on + strand at 385.274 kb on + strand, within PfGW456L13_330 at 385.274 kb on + strand, within PfGW456L13_330 at 385.275 kb on - strand, within PfGW456L13_330 at 385.275 kb on - strand, within PfGW456L13_330 at 385.275 kb on - strand, within PfGW456L13_330 at 385.366 kb on + strand, within PfGW456L13_330 at 385.423 kb on + strand, within PfGW456L13_330 at 385.423 kb on + strand, within PfGW456L13_330 at 385.423 kb on + strand, within PfGW456L13_330 at 385.423 kb on + strand, within PfGW456L13_330 at 385.423 kb on + strand, within PfGW456L13_330 at 385.423 kb on + strand, within PfGW456L13_330 at 385.423 kb on + strand, within PfGW456L13_330 at 385.424 kb on - strand, within PfGW456L13_330 at 385.424 kb on - strand, within PfGW456L13_330 at 385.424 kb on - strand, within PfGW456L13_330 at 385.424 kb on - strand, within PfGW456L13_330 at 385.471 kb on + strand, within PfGW456L13_330 at 385.472 kb on - strand, within PfGW456L13_330 at 385.475 kb on + strand, within PfGW456L13_330 at 385.475 kb on + strand, within PfGW456L13_330 at 385.476 kb on - strand, within PfGW456L13_330 at 385.476 kb on - strand, within PfGW456L13_330 at 385.476 kb on - strand, within PfGW456L13_330 at 385.476 kb on - strand, within PfGW456L13_330 at 385.476 kb on - strand, within PfGW456L13_330 at 385.476 kb on - strand, within PfGW456L13_330 at 385.476 kb on - strand, within PfGW456L13_330 at 385.502 kb on - strand, within PfGW456L13_330 at 385.531 kb on - strand, within PfGW456L13_330 at 385.531 kb on - strand, within PfGW456L13_330 at 385.585 kb on + strand, within PfGW456L13_330 at 385.586 kb on - strand, within PfGW456L13_330 at 385.586 kb on - strand, within PfGW456L13_330 at 385.586 kb on - strand, within PfGW456L13_330 at 385.657 kb on + strand, within PfGW456L13_330 at 385.879 kb on + strand, within PfGW456L13_330 at 385.879 kb on + strand, within PfGW456L13_330 at 386.120 kb on - strand, within PfGW456L13_330 at 386.149 kb on - strand, within PfGW456L13_330 at 386.149 kb on - strand, within PfGW456L13_330 at 386.159 kb on - strand, within PfGW456L13_330 at 386.331 kb on + strand, within PfGW456L13_330 at 386.332 kb on - strand, within PfGW456L13_330 at 386.581 kb on + strand at 386.581 kb on + strand at 386.581 kb on + strand at 386.582 kb on - strand at 386.582 kb on - strand at 386.582 kb on - strand at 386.587 kb on + strand at 386.651 kb on + strand, within PfGW456L13_331 at 386.651 kb on + strand, within PfGW456L13_331 at 386.732 kb on + strand, within PfGW456L13_331 at 386.732 kb on + strand, within PfGW456L13_331 at 386.732 kb on + strand, within PfGW456L13_331 at 386.732 kb on + strand, within PfGW456L13_331 at 386.732 kb on + strand, within PfGW456L13_331 at 386.732 kb on + strand, within PfGW456L13_331 at 386.732 kb on + strand, within PfGW456L13_331 at 386.733 kb on - strand, within PfGW456L13_331 at 386.733 kb on - strand, within PfGW456L13_331 at 386.733 kb on - strand, within PfGW456L13_331 at 386.733 kb on - strand, within PfGW456L13_331 at 386.733 kb on - strand, within PfGW456L13_331 at 386.733 kb on - strand, within PfGW456L13_331 at 386.768 kb on + strand, within PfGW456L13_331 at 386.768 kb on + strand, within PfGW456L13_331 at 386.768 kb on + strand, within PfGW456L13_331 at 386.769 kb on - strand, within PfGW456L13_331 at 386.769 kb on - strand, within PfGW456L13_331 at 386.783 kb on + strand at 386.783 kb on + strand, within PfGW456L13_331 at 386.783 kb on + strand, within PfGW456L13_331 at 386.784 kb on - strand, within PfGW456L13_331 at 386.784 kb on - strand, within PfGW456L13_331 at 386.784 kb on - strand, within PfGW456L13_331 at 386.784 kb on - strand, within PfGW456L13_331 at 386.784 kb on - strand, within PfGW456L13_331 at 386.885 kb on + strand, within PfGW456L13_331 at 386.972 kb on + strand, within PfGW456L13_331 at 386.972 kb on + strand, within PfGW456L13_331 at 387.008 kb on + strand, within PfGW456L13_331 at 387.008 kb on + strand, within PfGW456L13_331 at 387.008 kb on + strand, within PfGW456L13_331 at 387.008 kb on + strand, within PfGW456L13_331 at 387.008 kb on + strand, within PfGW456L13_331 at 387.008 kb on + strand, within PfGW456L13_331 at 387.008 kb on + strand, within PfGW456L13_331 at 387.009 kb on - strand, within PfGW456L13_331 at 387.009 kb on - strand, within PfGW456L13_331 at 387.018 kb on + strand, within PfGW456L13_331 at 387.019 kb on - strand, within PfGW456L13_331 at 387.032 kb on + strand, within PfGW456L13_331 at 387.033 kb on - strand, within PfGW456L13_331 at 387.067 kb on - strand, within PfGW456L13_331 at 387.067 kb on - strand, within PfGW456L13_331 at 387.160 kb on + strand at 387.161 kb on - strand at 387.192 kb on - strand at 387.192 kb on - strand at 387.249 kb on + strand, within PfGW456L13_332 at 387.249 kb on + strand, within PfGW456L13_332 at 387.369 kb on - strand, within PfGW456L13_332 at 387.406 kb on + strand, within PfGW456L13_332
Per-strain Table
Position Strand Gene LocusTag Fraction L-Histidine (N) remove 384,237 + -1.0 384,238 - -0.7 384,247 - -0.1 384,247 - +3.0 384,259 + -1.5 384,259 + +0.4 384,259 + +0.3 384,259 + +1.7 384,260 - +0.7 384,260 - +0.4 384,465 + PfGW456L13_329 0.28 +1.2 384,465 + PfGW456L13_329 0.28 +0.6 384,504 + PfGW456L13_329 0.33 +0.1 384,725 + PfGW456L13_329 0.63 +0.2 384,725 + PfGW456L13_329 0.63 +0.1 384,940 - +0.8 385,008 - -2.4 385,008 - -1.8 385,022 + +2.5 385,022 + -0.2 385,022 + +0.5 385,025 + -0.1 385,025 + -0.3 385,025 + -1.1 385,025 + +1.6 385,025 + +1.2 385,025 + +0.5 385,026 - -1.8 385,026 - -0.5 385,026 - -2.4 385,026 - +0.0 385,026 - -1.7 385,036 - -0.2 385,071 + -2.5 385,071 + -0.8 385,072 - -1.4 385,072 - -3.7 385,072 - -2.5 385,073 + -2.3 385,073 + -2.0 385,073 + -1.6 385,073 + -2.1 385,074 - -1.6 385,074 - -2.7 385,074 - -1.0 385,074 - -0.3 385,074 - -1.3 385,074 - -3.4 385,074 - -3.5 385,077 + -3.4 385,077 + -0.9 385,077 + -3.6 385,078 - -3.6 385,078 - -2.7 385,078 - -3.7 385,078 - -4.3 385,078 - -3.8 385,146 + -1.2 385,147 - -3.2 385,166 + -2.0 385,166 + -2.0 385,166 + -2.4 385,166 + -3.0 385,166 + -1.7 385,166 + -3.7 385,166 + -3.4 385,166 + -2.6 385,167 - -3.3 385,167 - -3.2 385,203 + -3.6 385,274 + PfGW456L13_330 0.12 -2.3 385,274 + PfGW456L13_330 0.12 -3.9 385,275 - PfGW456L13_330 0.12 -4.0 385,275 - PfGW456L13_330 0.12 -3.2 385,275 - PfGW456L13_330 0.12 +0.2 385,366 + PfGW456L13_330 0.19 -0.0 385,423 + PfGW456L13_330 0.23 -3.1 385,423 + PfGW456L13_330 0.23 -3.1 385,423 + PfGW456L13_330 0.23 -1.4 385,423 + PfGW456L13_330 0.23 -2.8 385,423 + PfGW456L13_330 0.23 -3.5 385,423 + PfGW456L13_330 0.23 -0.2 385,423 + PfGW456L13_330 0.23 -2.5 385,424 - PfGW456L13_330 0.23 -1.0 385,424 - PfGW456L13_330 0.23 -3.8 385,424 - PfGW456L13_330 0.23 -4.3 385,424 - PfGW456L13_330 0.23 -1.2 385,471 + PfGW456L13_330 0.26 -2.5 385,472 - PfGW456L13_330 0.26 -1.8 385,475 + PfGW456L13_330 0.27 -3.2 385,475 + PfGW456L13_330 0.27 -2.8 385,476 - PfGW456L13_330 0.27 -3.0 385,476 - PfGW456L13_330 0.27 -2.5 385,476 - PfGW456L13_330 0.27 -0.4 385,476 - PfGW456L13_330 0.27 -3.1 385,476 - PfGW456L13_330 0.27 -4.3 385,476 - PfGW456L13_330 0.27 -3.1 385,476 - PfGW456L13_330 0.27 -0.0 385,502 - PfGW456L13_330 0.29 -3.2 385,531 - PfGW456L13_330 0.31 -2.6 385,531 - PfGW456L13_330 0.31 -3.4 385,585 + PfGW456L13_330 0.35 -3.7 385,586 - PfGW456L13_330 0.35 -3.3 385,586 - PfGW456L13_330 0.35 -2.3 385,586 - PfGW456L13_330 0.35 -0.8 385,657 + PfGW456L13_330 0.40 -1.9 385,879 + PfGW456L13_330 0.56 -3.5 385,879 + PfGW456L13_330 0.56 -2.2 386,120 - PfGW456L13_330 0.74 -3.8 386,149 - PfGW456L13_330 0.76 -3.7 386,149 - PfGW456L13_330 0.76 -2.3 386,159 - PfGW456L13_330 0.77 -1.7 386,331 + PfGW456L13_330 0.89 -3.1 386,332 - PfGW456L13_330 0.89 -2.4 386,581 + -0.4 386,581 + -0.7 386,581 + +1.0 386,582 - +0.6 386,582 - +1.2 386,582 - +0.2 386,587 + -0.4 386,651 + PfGW456L13_331 0.11 -0.0 386,651 + PfGW456L13_331 0.11 +0.5 386,732 + PfGW456L13_331 0.25 +0.7 386,732 + PfGW456L13_331 0.25 -0.0 386,732 + PfGW456L13_331 0.25 -1.4 386,732 + PfGW456L13_331 0.25 +0.2 386,732 + PfGW456L13_331 0.25 +0.4 386,732 + PfGW456L13_331 0.25 -1.0 386,732 + PfGW456L13_331 0.25 +0.3 386,733 - PfGW456L13_331 0.25 -0.7 386,733 - PfGW456L13_331 0.25 -1.0 386,733 - PfGW456L13_331 0.25 +1.5 386,733 - PfGW456L13_331 0.25 -0.3 386,733 - PfGW456L13_331 0.25 -0.4 386,733 - PfGW456L13_331 0.25 +0.2 386,768 + PfGW456L13_331 0.31 +0.1 386,768 + PfGW456L13_331 0.31 -1.4 386,768 + PfGW456L13_331 0.31 -0.5 386,769 - PfGW456L13_331 0.31 +0.7 386,769 - PfGW456L13_331 0.31 +0.4 386,783 + -0.0 386,783 + PfGW456L13_331 0.34 +0.1 386,783 + PfGW456L13_331 0.34 +1.0 386,784 - PfGW456L13_331 0.34 -0.3 386,784 - PfGW456L13_331 0.34 -1.5 386,784 - PfGW456L13_331 0.34 +0.1 386,784 - PfGW456L13_331 0.34 +0.6 386,784 - PfGW456L13_331 0.34 -0.2 386,885 + PfGW456L13_331 0.52 +0.3 386,972 + PfGW456L13_331 0.67 -1.4 386,972 + PfGW456L13_331 0.67 +0.5 387,008 + PfGW456L13_331 0.73 +0.1 387,008 + PfGW456L13_331 0.73 -0.4 387,008 + PfGW456L13_331 0.73 -1.5 387,008 + PfGW456L13_331 0.73 -1.5 387,008 + PfGW456L13_331 0.73 -0.2 387,008 + PfGW456L13_331 0.73 -1.7 387,008 + PfGW456L13_331 0.73 +0.5 387,009 - PfGW456L13_331 0.74 -1.2 387,009 - PfGW456L13_331 0.74 -0.7 387,018 + PfGW456L13_331 0.75 +0.5 387,019 - PfGW456L13_331 0.75 +0.5 387,032 + PfGW456L13_331 0.78 -0.5 387,033 - PfGW456L13_331 0.78 -0.0 387,067 - PfGW456L13_331 0.84 -0.6 387,067 - PfGW456L13_331 0.84 +0.5 387,160 + -1.7 387,161 - +0.9 387,192 - -1.7 387,192 - -0.1 387,249 + PfGW456L13_332 0.23 +1.5 387,249 + PfGW456L13_332 0.23 +1.0 387,369 - PfGW456L13_332 0.70 -0.2 387,406 + PfGW456L13_332 0.85 +0.2
Or see this region's nucleotide sequence