Experiment: Lomefloxacin 0.0004 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_3167 and PfGW456L13_3168 are separated by 91 nucleotides PfGW456L13_3168 and PfGW456L13_3169 overlap by 4 nucleotides PfGW456L13_3169 and PfGW456L13_3170 are separated by 11 nucleotides
PfGW456L13_3167 - Transcriptional regulator, LysR family, at 3,547,512 to 3,548,366
_3167
PfGW456L13_3168 - Sensory histidine kinase QseC, at 3,548,458 to 3,549,825
_3168
PfGW456L13_3169 - Two-component system response regulator QseB, at 3,549,822 to 3,550,484
_3169
PfGW456L13_3170 - FIG00953528: hypothetical protein, at 3,550,496 to 3,551,140
_3170
Position (kb)
3548
3549
3550 Strain fitness (log2 ratio)
-2
-1
0
1
2
3 at 3547.512 kb on - strand at 3547.597 kb on + strand at 3547.597 kb on + strand at 3547.597 kb on + strand at 3547.598 kb on - strand, within PfGW456L13_3167 at 3547.598 kb on - strand, within PfGW456L13_3167 at 3547.598 kb on - strand, within PfGW456L13_3167 at 3547.848 kb on - strand, within PfGW456L13_3167 at 3548.133 kb on + strand, within PfGW456L13_3167 at 3548.134 kb on - strand, within PfGW456L13_3167 at 3548.149 kb on - strand, within PfGW456L13_3167 at 3548.149 kb on - strand, within PfGW456L13_3167 at 3548.149 kb on - strand, within PfGW456L13_3167 at 3548.149 kb on - strand, within PfGW456L13_3167 at 3548.240 kb on - strand, within PfGW456L13_3167 at 3548.292 kb on + strand at 3548.293 kb on - strand at 3548.293 kb on - strand at 3548.293 kb on - strand at 3548.482 kb on - strand at 3548.556 kb on + strand at 3548.556 kb on + strand at 3548.556 kb on + strand at 3548.556 kb on + strand at 3548.669 kb on + strand, within PfGW456L13_3168 at 3548.669 kb on + strand, within PfGW456L13_3168 at 3548.670 kb on - strand, within PfGW456L13_3168 at 3548.670 kb on - strand, within PfGW456L13_3168 at 3548.670 kb on - strand, within PfGW456L13_3168 at 3548.673 kb on + strand, within PfGW456L13_3168 at 3548.673 kb on + strand, within PfGW456L13_3168 at 3548.673 kb on + strand, within PfGW456L13_3168 at 3548.673 kb on + strand, within PfGW456L13_3168 at 3548.674 kb on - strand, within PfGW456L13_3168 at 3548.892 kb on + strand, within PfGW456L13_3168 at 3548.893 kb on - strand, within PfGW456L13_3168 at 3548.893 kb on - strand, within PfGW456L13_3168 at 3548.893 kb on - strand, within PfGW456L13_3168 at 3548.893 kb on - strand, within PfGW456L13_3168 at 3548.908 kb on - strand, within PfGW456L13_3168 at 3548.908 kb on - strand, within PfGW456L13_3168 at 3548.919 kb on + strand, within PfGW456L13_3168 at 3548.920 kb on - strand, within PfGW456L13_3168 at 3548.920 kb on - strand, within PfGW456L13_3168 at 3548.920 kb on - strand, within PfGW456L13_3168 at 3548.920 kb on - strand, within PfGW456L13_3168 at 3548.926 kb on + strand, within PfGW456L13_3168 at 3548.926 kb on + strand, within PfGW456L13_3168 at 3548.926 kb on + strand, within PfGW456L13_3168 at 3548.926 kb on + strand, within PfGW456L13_3168 at 3548.926 kb on + strand, within PfGW456L13_3168 at 3548.927 kb on - strand, within PfGW456L13_3168 at 3548.927 kb on - strand, within PfGW456L13_3168 at 3548.927 kb on - strand, within PfGW456L13_3168 at 3548.927 kb on - strand, within PfGW456L13_3168 at 3548.927 kb on - strand, within PfGW456L13_3168 at 3548.927 kb on - strand, within PfGW456L13_3168 at 3548.928 kb on + strand, within PfGW456L13_3168 at 3548.928 kb on + strand, within PfGW456L13_3168 at 3548.929 kb on - strand, within PfGW456L13_3168 at 3548.929 kb on - strand, within PfGW456L13_3168 at 3549.072 kb on + strand, within PfGW456L13_3168 at 3549.072 kb on + strand, within PfGW456L13_3168 at 3549.073 kb on - strand, within PfGW456L13_3168 at 3549.073 kb on - strand, within PfGW456L13_3168 at 3549.073 kb on - strand, within PfGW456L13_3168 at 3549.073 kb on - strand, within PfGW456L13_3168 at 3549.144 kb on + strand, within PfGW456L13_3168 at 3549.144 kb on + strand, within PfGW456L13_3168 at 3549.145 kb on - strand, within PfGW456L13_3168 at 3549.246 kb on + strand, within PfGW456L13_3168 at 3549.340 kb on + strand, within PfGW456L13_3168 at 3549.416 kb on - strand, within PfGW456L13_3168 at 3549.416 kb on - strand, within PfGW456L13_3168 at 3549.416 kb on - strand, within PfGW456L13_3168 at 3549.457 kb on + strand, within PfGW456L13_3168 at 3549.457 kb on + strand, within PfGW456L13_3168 at 3549.457 kb on + strand, within PfGW456L13_3168 at 3549.457 kb on + strand, within PfGW456L13_3168 at 3549.458 kb on - strand, within PfGW456L13_3168 at 3549.458 kb on - strand, within PfGW456L13_3168 at 3549.513 kb on + strand, within PfGW456L13_3168 at 3549.513 kb on + strand, within PfGW456L13_3168 at 3549.513 kb on + strand, within PfGW456L13_3168 at 3549.513 kb on + strand, within PfGW456L13_3168 at 3549.514 kb on - strand, within PfGW456L13_3168 at 3549.517 kb on + strand, within PfGW456L13_3168 at 3549.517 kb on + strand, within PfGW456L13_3168 at 3549.517 kb on + strand, within PfGW456L13_3168 at 3549.518 kb on - strand, within PfGW456L13_3168 at 3549.518 kb on - strand, within PfGW456L13_3168 at 3549.518 kb on - strand, within PfGW456L13_3168 at 3549.570 kb on - strand at 3549.626 kb on + strand, within PfGW456L13_3168 at 3549.626 kb on + strand, within PfGW456L13_3168 at 3549.626 kb on + strand, within PfGW456L13_3168 at 3549.626 kb on + strand, within PfGW456L13_3168 at 3549.626 kb on + strand, within PfGW456L13_3168 at 3549.627 kb on - strand, within PfGW456L13_3168 at 3549.627 kb on - strand, within PfGW456L13_3168 at 3549.627 kb on - strand, within PfGW456L13_3168 at 3549.660 kb on + strand, within PfGW456L13_3168 at 3549.660 kb on + strand, within PfGW456L13_3168 at 3549.660 kb on + strand, within PfGW456L13_3168 at 3549.660 kb on + strand, within PfGW456L13_3168 at 3549.661 kb on - strand, within PfGW456L13_3168 at 3549.677 kb on - strand, within PfGW456L13_3168 at 3549.677 kb on - strand, within PfGW456L13_3168 at 3549.710 kb on + strand at 3549.710 kb on + strand at 3549.711 kb on - strand at 3549.711 kb on - strand at 3549.711 kb on - strand at 3549.844 kb on + strand at 3549.950 kb on - strand, within PfGW456L13_3169 at 3550.021 kb on + strand, within PfGW456L13_3169 at 3550.022 kb on - strand, within PfGW456L13_3169 at 3550.022 kb on - strand, within PfGW456L13_3169 at 3550.028 kb on + strand, within PfGW456L13_3169 at 3550.028 kb on + strand, within PfGW456L13_3169 at 3550.028 kb on + strand, within PfGW456L13_3169 at 3550.029 kb on - strand, within PfGW456L13_3169 at 3550.057 kb on + strand, within PfGW456L13_3169 at 3550.057 kb on + strand, within PfGW456L13_3169 at 3550.057 kb on + strand, within PfGW456L13_3169 at 3550.058 kb on - strand, within PfGW456L13_3169 at 3550.058 kb on - strand, within PfGW456L13_3169 at 3550.091 kb on + strand, within PfGW456L13_3169 at 3550.149 kb on + strand, within PfGW456L13_3169 at 3550.150 kb on - strand, within PfGW456L13_3169 at 3550.193 kb on - strand, within PfGW456L13_3169 at 3550.410 kb on - strand, within PfGW456L13_3169 at 3550.411 kb on + strand, within PfGW456L13_3169 at 3550.412 kb on - strand at 3550.412 kb on - strand, within PfGW456L13_3169 at 3550.412 kb on - strand, within PfGW456L13_3169 at 3550.412 kb on - strand, within PfGW456L13_3169 at 3550.467 kb on + strand at 3550.468 kb on - strand at 3550.468 kb on - strand at 3550.468 kb on - strand at 3550.473 kb on + strand at 3550.474 kb on - strand at 3550.474 kb on - strand at 3550.476 kb on + strand at 3550.476 kb on + strand at 3550.476 kb on + strand at 3550.626 kb on + strand, within PfGW456L13_3170 at 3550.627 kb on - strand, within PfGW456L13_3170 at 3550.627 kb on - strand, within PfGW456L13_3170 at 3550.642 kb on - strand, within PfGW456L13_3170 at 3550.662 kb on + strand, within PfGW456L13_3170 at 3550.663 kb on - strand, within PfGW456L13_3170 at 3550.663 kb on - strand, within PfGW456L13_3170 at 3550.663 kb on - strand, within PfGW456L13_3170 at 3550.788 kb on + strand, within PfGW456L13_3170 at 3550.788 kb on + strand, within PfGW456L13_3170 at 3550.788 kb on + strand, within PfGW456L13_3170 at 3550.789 kb on - strand, within PfGW456L13_3170 at 3550.789 kb on - strand, within PfGW456L13_3170 at 3550.789 kb on - strand, within PfGW456L13_3170 at 3550.789 kb on - strand, within PfGW456L13_3170
Per-strain Table
Position Strand Gene LocusTag Fraction Lomefloxacin 0.0004 mM remove 3,547,512 - +0.2 3,547,597 + -0.3 3,547,597 + +2.2 3,547,597 + -0.6 3,547,598 - PfGW456L13_3167 0.10 +0.4 3,547,598 - PfGW456L13_3167 0.10 +0.3 3,547,598 - PfGW456L13_3167 0.10 -0.2 3,547,848 - PfGW456L13_3167 0.39 -2.7 3,548,133 + PfGW456L13_3167 0.73 -1.4 3,548,134 - PfGW456L13_3167 0.73 -1.6 3,548,149 - PfGW456L13_3167 0.75 -0.5 3,548,149 - PfGW456L13_3167 0.75 -1.3 3,548,149 - PfGW456L13_3167 0.75 +0.5 3,548,149 - PfGW456L13_3167 0.75 +0.3 3,548,240 - PfGW456L13_3167 0.85 +1.4 3,548,292 + +0.2 3,548,293 - -1.7 3,548,293 - +2.2 3,548,293 - +0.2 3,548,482 - +1.6 3,548,556 + -2.3 3,548,556 + +1.0 3,548,556 + +2.5 3,548,556 + -0.1 3,548,669 + PfGW456L13_3168 0.15 +0.6 3,548,669 + PfGW456L13_3168 0.15 +0.7 3,548,670 - PfGW456L13_3168 0.15 +2.1 3,548,670 - PfGW456L13_3168 0.15 -2.0 3,548,670 - PfGW456L13_3168 0.15 +0.3 3,548,673 + PfGW456L13_3168 0.16 -1.1 3,548,673 + PfGW456L13_3168 0.16 +1.7 3,548,673 + PfGW456L13_3168 0.16 -0.4 3,548,673 + PfGW456L13_3168 0.16 -0.8 3,548,674 - PfGW456L13_3168 0.16 +0.6 3,548,892 + PfGW456L13_3168 0.32 +0.6 3,548,893 - PfGW456L13_3168 0.32 -0.0 3,548,893 - PfGW456L13_3168 0.32 -0.8 3,548,893 - PfGW456L13_3168 0.32 -0.6 3,548,893 - PfGW456L13_3168 0.32 +0.4 3,548,908 - PfGW456L13_3168 0.33 +0.9 3,548,908 - PfGW456L13_3168 0.33 -1.0 3,548,919 + PfGW456L13_3168 0.34 -0.3 3,548,920 - PfGW456L13_3168 0.34 +1.3 3,548,920 - PfGW456L13_3168 0.34 +0.2 3,548,920 - PfGW456L13_3168 0.34 -0.9 3,548,920 - PfGW456L13_3168 0.34 -0.0 3,548,926 + PfGW456L13_3168 0.34 +0.2 3,548,926 + PfGW456L13_3168 0.34 -0.2 3,548,926 + PfGW456L13_3168 0.34 -1.3 3,548,926 + PfGW456L13_3168 0.34 -1.9 3,548,926 + PfGW456L13_3168 0.34 +1.7 3,548,927 - PfGW456L13_3168 0.34 +0.4 3,548,927 - PfGW456L13_3168 0.34 +0.2 3,548,927 - PfGW456L13_3168 0.34 +2.6 3,548,927 - PfGW456L13_3168 0.34 -0.2 3,548,927 - PfGW456L13_3168 0.34 +1.6 3,548,927 - PfGW456L13_3168 0.34 +1.0 3,548,928 + PfGW456L13_3168 0.34 +1.6 3,548,928 + PfGW456L13_3168 0.34 +1.9 3,548,929 - PfGW456L13_3168 0.34 -0.6 3,548,929 - PfGW456L13_3168 0.34 -1.6 3,549,072 + PfGW456L13_3168 0.45 -1.3 3,549,072 + PfGW456L13_3168 0.45 +0.6 3,549,073 - PfGW456L13_3168 0.45 +1.6 3,549,073 - PfGW456L13_3168 0.45 -1.0 3,549,073 - PfGW456L13_3168 0.45 +0.2 3,549,073 - PfGW456L13_3168 0.45 +1.8 3,549,144 + PfGW456L13_3168 0.50 -0.9 3,549,144 + PfGW456L13_3168 0.50 -0.4 3,549,145 - PfGW456L13_3168 0.50 +1.4 3,549,246 + PfGW456L13_3168 0.58 +0.7 3,549,340 + PfGW456L13_3168 0.64 +1.1 3,549,416 - PfGW456L13_3168 0.70 +1.5 3,549,416 - PfGW456L13_3168 0.70 -0.5 3,549,416 - PfGW456L13_3168 0.70 -0.7 3,549,457 + PfGW456L13_3168 0.73 -1.9 3,549,457 + PfGW456L13_3168 0.73 +1.8 3,549,457 + PfGW456L13_3168 0.73 -1.1 3,549,457 + PfGW456L13_3168 0.73 -0.6 3,549,458 - PfGW456L13_3168 0.73 +0.9 3,549,458 - PfGW456L13_3168 0.73 +1.2 3,549,513 + PfGW456L13_3168 0.77 -1.1 3,549,513 + PfGW456L13_3168 0.77 -1.4 3,549,513 + PfGW456L13_3168 0.77 -1.5 3,549,513 + PfGW456L13_3168 0.77 -1.5 3,549,514 - PfGW456L13_3168 0.77 +2.4 3,549,517 + PfGW456L13_3168 0.77 +0.6 3,549,517 + PfGW456L13_3168 0.77 -1.3 3,549,517 + PfGW456L13_3168 0.77 -1.6 3,549,518 - PfGW456L13_3168 0.77 -0.0 3,549,518 - PfGW456L13_3168 0.77 -1.3 3,549,518 - PfGW456L13_3168 0.77 -0.6 3,549,570 - +1.2 3,549,626 + PfGW456L13_3168 0.85 +0.5 3,549,626 + PfGW456L13_3168 0.85 +0.7 3,549,626 + PfGW456L13_3168 0.85 -0.6 3,549,626 + PfGW456L13_3168 0.85 +0.2 3,549,626 + PfGW456L13_3168 0.85 +1.5 3,549,627 - PfGW456L13_3168 0.85 +1.6 3,549,627 - PfGW456L13_3168 0.85 +0.6 3,549,627 - PfGW456L13_3168 0.85 -0.0 3,549,660 + PfGW456L13_3168 0.88 +1.0 3,549,660 + PfGW456L13_3168 0.88 -0.1 3,549,660 + PfGW456L13_3168 0.88 +2.6 3,549,660 + PfGW456L13_3168 0.88 +0.6 3,549,661 - PfGW456L13_3168 0.88 -0.9 3,549,677 - PfGW456L13_3168 0.89 +0.6 3,549,677 - PfGW456L13_3168 0.89 +1.7 3,549,710 + +0.2 3,549,710 + +0.5 3,549,711 - +1.6 3,549,711 - +0.6 3,549,711 - +0.0 3,549,844 + +1.6 3,549,950 - PfGW456L13_3169 0.19 -0.4 3,550,021 + PfGW456L13_3169 0.30 -0.8 3,550,022 - PfGW456L13_3169 0.30 -0.2 3,550,022 - PfGW456L13_3169 0.30 +0.2 3,550,028 + PfGW456L13_3169 0.31 +0.9 3,550,028 + PfGW456L13_3169 0.31 +2.6 3,550,028 + PfGW456L13_3169 0.31 -1.2 3,550,029 - PfGW456L13_3169 0.31 +0.6 3,550,057 + PfGW456L13_3169 0.35 -2.1 3,550,057 + PfGW456L13_3169 0.35 +1.0 3,550,057 + PfGW456L13_3169 0.35 +0.9 3,550,058 - PfGW456L13_3169 0.36 -0.8 3,550,058 - PfGW456L13_3169 0.36 +2.2 3,550,091 + PfGW456L13_3169 0.41 +1.2 3,550,149 + PfGW456L13_3169 0.49 -0.8 3,550,150 - PfGW456L13_3169 0.49 +0.3 3,550,193 - PfGW456L13_3169 0.56 +1.2 3,550,410 - PfGW456L13_3169 0.89 +0.2 3,550,411 + PfGW456L13_3169 0.89 -0.6 3,550,412 - +2.2 3,550,412 - PfGW456L13_3169 0.89 -1.0 3,550,412 - PfGW456L13_3169 0.89 +1.2 3,550,412 - PfGW456L13_3169 0.89 +1.0 3,550,467 + +0.8 3,550,468 - +0.2 3,550,468 - +1.4 3,550,468 - -0.1 3,550,473 + +0.0 3,550,474 - -2.0 3,550,474 - -1.1 3,550,476 + +1.6 3,550,476 + -0.2 3,550,476 + -0.8 3,550,626 + PfGW456L13_3170 0.20 +0.6 3,550,627 - PfGW456L13_3170 0.20 -1.7 3,550,627 - PfGW456L13_3170 0.20 -0.6 3,550,642 - PfGW456L13_3170 0.23 -0.4 3,550,662 + PfGW456L13_3170 0.26 +0.6 3,550,663 - PfGW456L13_3170 0.26 -0.6 3,550,663 - PfGW456L13_3170 0.26 -1.8 3,550,663 - PfGW456L13_3170 0.26 -0.8 3,550,788 + PfGW456L13_3170 0.45 +1.0 3,550,788 + PfGW456L13_3170 0.45 +1.2 3,550,788 + PfGW456L13_3170 0.45 +0.1 3,550,789 - PfGW456L13_3170 0.45 -1.2 3,550,789 - PfGW456L13_3170 0.45 +2.8 3,550,789 - PfGW456L13_3170 0.45 +0.7 3,550,789 - PfGW456L13_3170 0.45 -2.0
Or see this region's nucleotide sequence