Experiment: Lomefloxacin 0.0004 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_2523 and PfGW456L13_2524 are separated by 13 nucleotides PfGW456L13_2524 and PfGW456L13_2525 overlap by 13 nucleotides PfGW456L13_2525 and PfGW456L13_2526 are separated by 9 nucleotides
PfGW456L13_2523 - Probable phenylacetic acid degradation NADH oxidoreductase paaE (EC 1.-.-.-), at 2,790,011 to 2,791,093
_2523
PfGW456L13_2524 - Short-chain dehydrogenase/reductase SDR, at 2,791,107 to 2,791,862
_2524
PfGW456L13_2525 - Fumarate reductase flavoprotein subunit (EC 1.3.99.1), at 2,791,850 to 2,793,529
_2525
PfGW456L13_2526 - 4-hydroxyphenylacetate 3-monooxygenase, reductase component (EC 1.6.8.-), at 2,793,539 to 2,794,054
_2526
Position (kb)
2791
2792
2793
2794 Strain fitness (log2 ratio)
-2
-1
0
1
2
3 at 2790.948 kb on + strand, within PfGW456L13_2523 at 2791.501 kb on + strand, within PfGW456L13_2524 at 2791.502 kb on - strand, within PfGW456L13_2524 at 2791.519 kb on + strand, within PfGW456L13_2524 at 2791.519 kb on + strand, within PfGW456L13_2524 at 2791.614 kb on + strand, within PfGW456L13_2524 at 2791.614 kb on + strand, within PfGW456L13_2524 at 2791.614 kb on + strand, within PfGW456L13_2524 at 2791.615 kb on - strand, within PfGW456L13_2524 at 2791.762 kb on - strand, within PfGW456L13_2524 at 2791.765 kb on - strand, within PfGW456L13_2524 at 2791.765 kb on - strand, within PfGW456L13_2524 at 2791.851 kb on + strand at 2791.851 kb on + strand at 2791.852 kb on - strand at 2791.968 kb on + strand at 2791.968 kb on + strand at 2791.969 kb on - strand at 2791.969 kb on - strand at 2791.969 kb on - strand at 2792.011 kb on - strand at 2792.123 kb on + strand, within PfGW456L13_2525 at 2792.123 kb on + strand, within PfGW456L13_2525 at 2792.136 kb on + strand, within PfGW456L13_2525 at 2792.220 kb on + strand, within PfGW456L13_2525 at 2792.478 kb on + strand, within PfGW456L13_2525 at 2792.649 kb on + strand, within PfGW456L13_2525 at 2792.708 kb on + strand, within PfGW456L13_2525 at 2792.709 kb on - strand, within PfGW456L13_2525 at 2792.805 kb on + strand, within PfGW456L13_2525 at 2792.805 kb on + strand, within PfGW456L13_2525 at 2792.805 kb on + strand, within PfGW456L13_2525 at 2792.805 kb on + strand, within PfGW456L13_2525 at 2792.806 kb on - strand, within PfGW456L13_2525 at 2792.806 kb on - strand, within PfGW456L13_2525 at 2792.809 kb on + strand, within PfGW456L13_2525 at 2792.809 kb on + strand, within PfGW456L13_2525 at 2792.809 kb on + strand, within PfGW456L13_2525 at 2792.809 kb on + strand, within PfGW456L13_2525 at 2792.809 kb on + strand, within PfGW456L13_2525 at 2792.809 kb on + strand, within PfGW456L13_2525 at 2792.809 kb on + strand, within PfGW456L13_2525 at 2792.809 kb on + strand, within PfGW456L13_2525 at 2792.809 kb on + strand, within PfGW456L13_2525 at 2792.809 kb on + strand, within PfGW456L13_2525 at 2792.809 kb on + strand, within PfGW456L13_2525 at 2792.810 kb on - strand, within PfGW456L13_2525 at 2792.810 kb on - strand, within PfGW456L13_2525 at 2792.810 kb on - strand, within PfGW456L13_2525 at 2792.810 kb on - strand, within PfGW456L13_2525 at 2792.810 kb on - strand, within PfGW456L13_2525 at 2792.810 kb on - strand, within PfGW456L13_2525 at 2792.810 kb on - strand, within PfGW456L13_2525 at 2792.810 kb on - strand, within PfGW456L13_2525 at 2793.064 kb on - strand, within PfGW456L13_2525 at 2793.090 kb on + strand, within PfGW456L13_2525 at 2793.091 kb on - strand, within PfGW456L13_2525 at 2793.094 kb on - strand, within PfGW456L13_2525 at 2793.094 kb on - strand, within PfGW456L13_2525 at 2793.094 kb on - strand, within PfGW456L13_2525 at 2793.094 kb on - strand, within PfGW456L13_2525 at 2793.094 kb on - strand, within PfGW456L13_2525 at 2793.099 kb on + strand, within PfGW456L13_2525 at 2793.099 kb on + strand, within PfGW456L13_2525 at 2793.099 kb on + strand, within PfGW456L13_2525 at 2793.099 kb on + strand, within PfGW456L13_2525 at 2793.099 kb on + strand, within PfGW456L13_2525 at 2793.099 kb on + strand, within PfGW456L13_2525 at 2793.100 kb on - strand, within PfGW456L13_2525 at 2793.100 kb on - strand, within PfGW456L13_2525 at 2793.100 kb on - strand, within PfGW456L13_2525 at 2793.100 kb on - strand, within PfGW456L13_2525 at 2793.100 kb on - strand, within PfGW456L13_2525 at 2793.102 kb on + strand, within PfGW456L13_2525 at 2793.103 kb on - strand, within PfGW456L13_2525 at 2793.103 kb on - strand, within PfGW456L13_2525 at 2793.103 kb on - strand, within PfGW456L13_2525 at 2793.103 kb on - strand, within PfGW456L13_2525 at 2793.113 kb on - strand, within PfGW456L13_2525 at 2793.127 kb on + strand, within PfGW456L13_2525 at 2793.255 kb on + strand, within PfGW456L13_2525 at 2793.256 kb on - strand, within PfGW456L13_2525 at 2793.325 kb on - strand, within PfGW456L13_2525 at 2793.585 kb on + strand at 2793.585 kb on + strand at 2793.585 kb on + strand at 2793.586 kb on - strand at 2793.586 kb on - strand at 2793.586 kb on - strand at 2793.586 kb on - strand at 2793.672 kb on + strand, within PfGW456L13_2526 at 2793.726 kb on + strand, within PfGW456L13_2526 at 2793.985 kb on + strand, within PfGW456L13_2526 at 2794.135 kb on + strand at 2794.135 kb on + strand at 2794.136 kb on - strand at 2794.182 kb on - strand at 2794.182 kb on - strand at 2794.182 kb on - strand at 2794.182 kb on - strand at 2794.182 kb on - strand at 2794.182 kb on - strand at 2794.182 kb on - strand at 2794.186 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Lomefloxacin 0.0004 mM remove 2,790,948 + PfGW456L13_2523 0.87 -0.3 2,791,501 + PfGW456L13_2524 0.52 +0.8 2,791,502 - PfGW456L13_2524 0.52 -0.8 2,791,519 + PfGW456L13_2524 0.54 -1.3 2,791,519 + PfGW456L13_2524 0.54 -2.1 2,791,614 + PfGW456L13_2524 0.67 +0.7 2,791,614 + PfGW456L13_2524 0.67 +1.4 2,791,614 + PfGW456L13_2524 0.67 +2.9 2,791,615 - PfGW456L13_2524 0.67 -0.3 2,791,762 - PfGW456L13_2524 0.87 +0.3 2,791,765 - PfGW456L13_2524 0.87 -1.0 2,791,765 - PfGW456L13_2524 0.87 +0.3 2,791,851 + +0.5 2,791,851 + -1.8 2,791,852 - +0.3 2,791,968 + -2.5 2,791,968 + -0.2 2,791,969 - -0.1 2,791,969 - +0.2 2,791,969 - -1.0 2,792,011 - -1.1 2,792,123 + PfGW456L13_2525 0.16 +0.2 2,792,123 + PfGW456L13_2525 0.16 +0.0 2,792,136 + PfGW456L13_2525 0.17 -0.6 2,792,220 + PfGW456L13_2525 0.22 -1.3 2,792,478 + PfGW456L13_2525 0.37 +0.2 2,792,649 + PfGW456L13_2525 0.48 +0.3 2,792,708 + PfGW456L13_2525 0.51 +1.3 2,792,709 - PfGW456L13_2525 0.51 +0.5 2,792,805 + PfGW456L13_2525 0.57 -1.2 2,792,805 + PfGW456L13_2525 0.57 -0.3 2,792,805 + PfGW456L13_2525 0.57 -0.0 2,792,805 + PfGW456L13_2525 0.57 -1.5 2,792,806 - PfGW456L13_2525 0.57 -1.4 2,792,806 - PfGW456L13_2525 0.57 +0.6 2,792,809 + PfGW456L13_2525 0.57 -0.3 2,792,809 + PfGW456L13_2525 0.57 -0.4 2,792,809 + PfGW456L13_2525 0.57 -1.5 2,792,809 + PfGW456L13_2525 0.57 +1.7 2,792,809 + PfGW456L13_2525 0.57 +2.3 2,792,809 + PfGW456L13_2525 0.57 -0.8 2,792,809 + PfGW456L13_2525 0.57 +0.3 2,792,809 + PfGW456L13_2525 0.57 -1.3 2,792,809 + PfGW456L13_2525 0.57 -0.1 2,792,809 + PfGW456L13_2525 0.57 -0.3 2,792,809 + PfGW456L13_2525 0.57 -1.4 2,792,810 - PfGW456L13_2525 0.57 -0.1 2,792,810 - PfGW456L13_2525 0.57 +0.1 2,792,810 - PfGW456L13_2525 0.57 +0.9 2,792,810 - PfGW456L13_2525 0.57 +1.0 2,792,810 - PfGW456L13_2525 0.57 -2.0 2,792,810 - PfGW456L13_2525 0.57 +0.3 2,792,810 - PfGW456L13_2525 0.57 -0.6 2,792,810 - PfGW456L13_2525 0.57 -1.7 2,793,064 - PfGW456L13_2525 0.72 -0.1 2,793,090 + PfGW456L13_2525 0.74 +0.6 2,793,091 - PfGW456L13_2525 0.74 +0.0 2,793,094 - PfGW456L13_2525 0.74 -0.4 2,793,094 - PfGW456L13_2525 0.74 -1.8 2,793,094 - PfGW456L13_2525 0.74 +0.7 2,793,094 - PfGW456L13_2525 0.74 +1.3 2,793,094 - PfGW456L13_2525 0.74 +0.5 2,793,099 + PfGW456L13_2525 0.74 +0.3 2,793,099 + PfGW456L13_2525 0.74 +1.5 2,793,099 + PfGW456L13_2525 0.74 -0.9 2,793,099 + PfGW456L13_2525 0.74 +1.4 2,793,099 + PfGW456L13_2525 0.74 -0.8 2,793,099 + PfGW456L13_2525 0.74 -2.3 2,793,100 - PfGW456L13_2525 0.74 +0.0 2,793,100 - PfGW456L13_2525 0.74 +0.4 2,793,100 - PfGW456L13_2525 0.74 -2.3 2,793,100 - PfGW456L13_2525 0.74 -0.4 2,793,100 - PfGW456L13_2525 0.74 -0.1 2,793,102 + PfGW456L13_2525 0.75 +0.9 2,793,103 - PfGW456L13_2525 0.75 +0.7 2,793,103 - PfGW456L13_2525 0.75 -2.4 2,793,103 - PfGW456L13_2525 0.75 -0.1 2,793,103 - PfGW456L13_2525 0.75 +0.1 2,793,113 - PfGW456L13_2525 0.75 -0.7 2,793,127 + PfGW456L13_2525 0.76 +0.5 2,793,255 + PfGW456L13_2525 0.84 -1.2 2,793,256 - PfGW456L13_2525 0.84 -0.1 2,793,325 - PfGW456L13_2525 0.88 -0.7 2,793,585 + +0.8 2,793,585 + +0.9 2,793,585 + -0.4 2,793,586 - -0.4 2,793,586 - +2.5 2,793,586 - -1.2 2,793,586 - +2.1 2,793,672 + PfGW456L13_2526 0.26 +1.8 2,793,726 + PfGW456L13_2526 0.36 -1.6 2,793,985 + PfGW456L13_2526 0.86 -0.2 2,794,135 + -0.7 2,794,135 + +0.2 2,794,136 - +1.6 2,794,182 - -1.9 2,794,182 - +1.1 2,794,182 - -0.7 2,794,182 - -0.4 2,794,182 - +0.3 2,794,182 - +1.3 2,794,182 - +0.6 2,794,186 - -0.7
Or see this region's nucleotide sequence