Experiment: Cephalothin 3 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_4306 and PfGW456L13_4307 are separated by 284 nucleotides PfGW456L13_4307 and PfGW456L13_4308 are separated by 14 nucleotides PfGW456L13_4308 and PfGW456L13_4309 overlap by 8 nucleotides PfGW456L13_4309 and PfGW456L13_4310 overlap by 4 nucleotides PfGW456L13_4310 and PfGW456L13_4311 overlap by 4 nucleotides
PfGW456L13_4306 - ATP-binding protein PhnN; Guanylate kinase (EC 2.7.4.8), at 4,822,548 to 4,823,219
_4306
PfGW456L13_4307 - Cytochrome c heme lyase subunit CcmH, at 4,823,504 to 4,823,911
_4307
PfGW456L13_4308 - Cytochrome c heme lyase subunit CcmH, at 4,823,926 to 4,825,128
_4308
PfGW456L13_4309 - Cytochrome c heme lyase subunit CcmL, at 4,825,121 to 4,825,594
_4309
PfGW456L13_4310 - Cytochrome c-type biogenesis protein CcmG/DsbE, thiol:disulfide oxidoreductase, at 4,825,591 to 4,826,127
_4310
PfGW456L13_4311 - Cytochrome c heme lyase subunit CcmF, at 4,826,124 to 4,828,112
_4311
Position (kb)
4823
4824
4825
4826 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 4823.028 kb on - strand, within PfGW456L13_4306 at 4823.028 kb on - strand, within PfGW456L13_4306 at 4823.080 kb on + strand, within PfGW456L13_4306 at 4823.080 kb on + strand, within PfGW456L13_4306 at 4823.080 kb on + strand, within PfGW456L13_4306 at 4823.081 kb on - strand, within PfGW456L13_4306 at 4823.081 kb on - strand, within PfGW456L13_4306 at 4823.081 kb on - strand, within PfGW456L13_4306 at 4823.081 kb on - strand, within PfGW456L13_4306 at 4823.192 kb on + strand at 4823.192 kb on + strand at 4823.246 kb on + strand at 4823.332 kb on - strand at 4823.339 kb on + strand at 4823.339 kb on + strand at 4823.339 kb on + strand at 4823.339 kb on + strand at 4823.339 kb on + strand at 4823.339 kb on + strand at 4823.339 kb on + strand at 4823.339 kb on + strand at 4823.339 kb on + strand at 4823.339 kb on + strand at 4823.339 kb on + strand at 4823.339 kb on + strand at 4823.339 kb on + strand at 4823.339 kb on + strand at 4823.339 kb on + strand at 4823.339 kb on + strand at 4823.339 kb on + strand at 4823.339 kb on + strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.340 kb on - strand at 4823.343 kb on + strand at 4823.343 kb on + strand at 4823.343 kb on + strand at 4823.344 kb on - strand at 4823.369 kb on + strand at 4823.369 kb on + strand at 4823.369 kb on + strand at 4823.370 kb on - strand at 4823.370 kb on - strand at 4823.370 kb on - strand at 4823.370 kb on - strand at 4823.383 kb on + strand at 4823.383 kb on + strand at 4823.383 kb on + strand at 4823.383 kb on + strand at 4823.383 kb on + strand at 4823.384 kb on - strand at 4823.384 kb on - strand at 4823.384 kb on - strand at 4823.387 kb on + strand at 4823.387 kb on + strand at 4823.387 kb on + strand at 4823.387 kb on + strand at 4823.387 kb on + strand at 4823.387 kb on + strand at 4823.387 kb on + strand at 4823.387 kb on + strand at 4823.387 kb on + strand at 4823.388 kb on - strand at 4823.388 kb on - strand at 4823.388 kb on - strand at 4823.388 kb on - strand at 4823.388 kb on - strand at 4823.388 kb on - strand at 4823.388 kb on - strand at 4823.388 kb on - strand at 4823.388 kb on - strand at 4823.554 kb on + strand, within PfGW456L13_4307 at 4823.554 kb on + strand, within PfGW456L13_4307 at 4823.554 kb on + strand, within PfGW456L13_4307 at 4823.613 kb on + strand, within PfGW456L13_4307 at 4823.613 kb on + strand, within PfGW456L13_4307 at 4823.613 kb on + strand, within PfGW456L13_4307 at 4823.613 kb on + strand, within PfGW456L13_4307 at 4823.613 kb on + strand, within PfGW456L13_4307 at 4823.614 kb on - strand, within PfGW456L13_4307 at 4823.614 kb on - strand, within PfGW456L13_4307 at 4823.614 kb on - strand, within PfGW456L13_4307 at 4823.614 kb on - strand, within PfGW456L13_4307 at 4823.614 kb on - strand, within PfGW456L13_4307 at 4823.614 kb on - strand, within PfGW456L13_4307 at 4823.614 kb on - strand, within PfGW456L13_4307 at 4823.617 kb on + strand, within PfGW456L13_4307 at 4823.617 kb on + strand, within PfGW456L13_4307 at 4823.617 kb on + strand, within PfGW456L13_4307 at 4823.618 kb on - strand, within PfGW456L13_4307 at 4823.618 kb on - strand, within PfGW456L13_4307 at 4823.618 kb on - strand, within PfGW456L13_4307 at 4823.618 kb on - strand, within PfGW456L13_4307 at 4823.618 kb on - strand, within PfGW456L13_4307 at 4823.618 kb on - strand, within PfGW456L13_4307 at 4823.629 kb on - strand, within PfGW456L13_4307 at 4823.635 kb on + strand at 4823.658 kb on + strand, within PfGW456L13_4307 at 4823.658 kb on + strand, within PfGW456L13_4307 at 4823.658 kb on + strand, within PfGW456L13_4307 at 4823.658 kb on + strand, within PfGW456L13_4307 at 4823.658 kb on + strand, within PfGW456L13_4307 at 4823.658 kb on + strand, within PfGW456L13_4307 at 4823.658 kb on + strand, within PfGW456L13_4307 at 4823.658 kb on + strand, within PfGW456L13_4307 at 4823.658 kb on + strand, within PfGW456L13_4307 at 4823.658 kb on + strand, within PfGW456L13_4307 at 4823.658 kb on + strand, within PfGW456L13_4307 at 4823.659 kb on - strand, within PfGW456L13_4307 at 4823.659 kb on - strand, within PfGW456L13_4307 at 4823.659 kb on - strand, within PfGW456L13_4307 at 4823.659 kb on - strand, within PfGW456L13_4307 at 4823.659 kb on - strand, within PfGW456L13_4307 at 4823.659 kb on - strand, within PfGW456L13_4307 at 4823.659 kb on - strand, within PfGW456L13_4307 at 4823.659 kb on - strand, within PfGW456L13_4307 at 4823.659 kb on - strand, within PfGW456L13_4307 at 4823.659 kb on - strand, within PfGW456L13_4307 at 4823.659 kb on - strand, within PfGW456L13_4307 at 4823.659 kb on - strand, within PfGW456L13_4307 at 4823.659 kb on - strand, within PfGW456L13_4307 at 4823.659 kb on - strand, within PfGW456L13_4307 at 4823.659 kb on - strand, within PfGW456L13_4307 at 4823.659 kb on - strand, within PfGW456L13_4307 at 4823.686 kb on + strand, within PfGW456L13_4307 at 4823.865 kb on - strand, within PfGW456L13_4307 at 4823.893 kb on + strand at 4823.894 kb on - strand at 4823.927 kb on + strand at 4823.927 kb on + strand at 4823.928 kb on - strand at 4823.928 kb on - strand at 4824.111 kb on - strand, within PfGW456L13_4308 at 4824.545 kb on + strand, within PfGW456L13_4308 at 4824.650 kb on + strand, within PfGW456L13_4308 at 4824.650 kb on + strand, within PfGW456L13_4308 at 4824.650 kb on + strand, within PfGW456L13_4308 at 4824.650 kb on + strand, within PfGW456L13_4308 at 4824.651 kb on - strand, within PfGW456L13_4308 at 4824.651 kb on - strand, within PfGW456L13_4308 at 4824.651 kb on - strand, within PfGW456L13_4308 at 4824.651 kb on - strand, within PfGW456L13_4308 at 4824.651 kb on - strand, within PfGW456L13_4308 at 4824.668 kb on + strand, within PfGW456L13_4308 at 4824.668 kb on + strand, within PfGW456L13_4308 at 4824.669 kb on - strand, within PfGW456L13_4308 at 4824.669 kb on - strand, within PfGW456L13_4308 at 4824.669 kb on - strand, within PfGW456L13_4308 at 4824.800 kb on + strand, within PfGW456L13_4308 at 4824.800 kb on + strand, within PfGW456L13_4308 at 4825.139 kb on - strand at 4825.623 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Cephalothin 3 mg/ml remove 4,823,028 - PfGW456L13_4306 0.71 +0.4 4,823,028 - PfGW456L13_4306 0.71 -1.5 4,823,080 + PfGW456L13_4306 0.79 +1.1 4,823,080 + PfGW456L13_4306 0.79 +0.5 4,823,080 + PfGW456L13_4306 0.79 -1.8 4,823,081 - PfGW456L13_4306 0.79 -2.5 4,823,081 - PfGW456L13_4306 0.79 -1.2 4,823,081 - PfGW456L13_4306 0.79 -1.7 4,823,081 - PfGW456L13_4306 0.79 -0.1 4,823,192 + +0.3 4,823,192 + -0.2 4,823,246 + +0.6 4,823,332 - +0.7 4,823,339 + -0.2 4,823,339 + -1.3 4,823,339 + +0.9 4,823,339 + +0.7 4,823,339 + +0.3 4,823,339 + -1.4 4,823,339 + +1.4 4,823,339 + -1.0 4,823,339 + +0.7 4,823,339 + +0.0 4,823,339 + +1.1 4,823,339 + +1.3 4,823,339 + -0.3 4,823,339 + +0.0 4,823,339 + +0.9 4,823,339 + -0.5 4,823,339 + -0.0 4,823,339 + +0.9 4,823,340 - -0.5 4,823,340 - +0.3 4,823,340 - +1.1 4,823,340 - -0.1 4,823,340 - -1.0 4,823,340 - +0.2 4,823,340 - -0.4 4,823,340 - -0.6 4,823,340 - -0.9 4,823,340 - -1.1 4,823,340 - +0.2 4,823,340 - -0.1 4,823,340 - -0.1 4,823,340 - -0.8 4,823,340 - +0.7 4,823,340 - +0.2 4,823,340 - -0.1 4,823,340 - +0.4 4,823,340 - -0.1 4,823,340 - -0.1 4,823,340 - +1.3 4,823,343 + -1.6 4,823,343 + +0.1 4,823,343 + +0.5 4,823,344 - -0.1 4,823,369 + -0.1 4,823,369 + +0.1 4,823,369 + -0.6 4,823,370 - +0.2 4,823,370 - -0.0 4,823,370 - +1.3 4,823,370 - +0.1 4,823,383 + -0.0 4,823,383 + +0.1 4,823,383 + +0.8 4,823,383 + +0.6 4,823,383 + -0.1 4,823,384 - -1.7 4,823,384 - -0.7 4,823,384 - -1.1 4,823,387 + -1.3 4,823,387 + +0.5 4,823,387 + -1.1 4,823,387 + -0.4 4,823,387 + +0.3 4,823,387 + +1.9 4,823,387 + -0.1 4,823,387 + +0.9 4,823,387 + +1.0 4,823,388 - +2.7 4,823,388 - -0.0 4,823,388 - -1.1 4,823,388 - +0.2 4,823,388 - -0.1 4,823,388 - -0.4 4,823,388 - -1.4 4,823,388 - -0.3 4,823,388 - +0.3 4,823,554 + PfGW456L13_4307 0.12 +0.0 4,823,554 + PfGW456L13_4307 0.12 -0.3 4,823,554 + PfGW456L13_4307 0.12 -2.8 4,823,613 + PfGW456L13_4307 0.27 -0.5 4,823,613 + PfGW456L13_4307 0.27 -0.2 4,823,613 + PfGW456L13_4307 0.27 -1.1 4,823,613 + PfGW456L13_4307 0.27 -1.6 4,823,613 + PfGW456L13_4307 0.27 +0.1 4,823,614 - PfGW456L13_4307 0.27 +0.4 4,823,614 - PfGW456L13_4307 0.27 -0.3 4,823,614 - PfGW456L13_4307 0.27 -0.9 4,823,614 - PfGW456L13_4307 0.27 -0.1 4,823,614 - PfGW456L13_4307 0.27 -0.8 4,823,614 - PfGW456L13_4307 0.27 -0.0 4,823,614 - PfGW456L13_4307 0.27 +2.4 4,823,617 + PfGW456L13_4307 0.28 -0.5 4,823,617 + PfGW456L13_4307 0.28 -0.1 4,823,617 + PfGW456L13_4307 0.28 -0.7 4,823,618 - PfGW456L13_4307 0.28 +0.8 4,823,618 - PfGW456L13_4307 0.28 +0.9 4,823,618 - PfGW456L13_4307 0.28 +0.6 4,823,618 - PfGW456L13_4307 0.28 +1.6 4,823,618 - PfGW456L13_4307 0.28 +0.9 4,823,618 - PfGW456L13_4307 0.28 +1.1 4,823,629 - PfGW456L13_4307 0.31 +1.0 4,823,635 + +0.9 4,823,658 + PfGW456L13_4307 0.38 -0.9 4,823,658 + PfGW456L13_4307 0.38 +0.2 4,823,658 + PfGW456L13_4307 0.38 +0.1 4,823,658 + PfGW456L13_4307 0.38 -0.9 4,823,658 + PfGW456L13_4307 0.38 -1.7 4,823,658 + PfGW456L13_4307 0.38 -0.4 4,823,658 + PfGW456L13_4307 0.38 +0.6 4,823,658 + PfGW456L13_4307 0.38 -0.4 4,823,658 + PfGW456L13_4307 0.38 +0.9 4,823,658 + PfGW456L13_4307 0.38 -0.4 4,823,658 + PfGW456L13_4307 0.38 +0.4 4,823,659 - PfGW456L13_4307 0.38 -0.6 4,823,659 - PfGW456L13_4307 0.38 -0.5 4,823,659 - PfGW456L13_4307 0.38 -0.2 4,823,659 - PfGW456L13_4307 0.38 -0.8 4,823,659 - PfGW456L13_4307 0.38 +0.9 4,823,659 - PfGW456L13_4307 0.38 -0.1 4,823,659 - PfGW456L13_4307 0.38 +1.3 4,823,659 - PfGW456L13_4307 0.38 +1.0 4,823,659 - PfGW456L13_4307 0.38 +0.2 4,823,659 - PfGW456L13_4307 0.38 -0.0 4,823,659 - PfGW456L13_4307 0.38 -0.3 4,823,659 - PfGW456L13_4307 0.38 +0.1 4,823,659 - PfGW456L13_4307 0.38 -0.7 4,823,659 - PfGW456L13_4307 0.38 +2.2 4,823,659 - PfGW456L13_4307 0.38 +0.2 4,823,659 - PfGW456L13_4307 0.38 +0.2 4,823,686 + PfGW456L13_4307 0.45 -0.1 4,823,865 - PfGW456L13_4307 0.88 -0.2 4,823,893 + +1.5 4,823,894 - +2.4 4,823,927 + +1.0 4,823,927 + +1.3 4,823,928 - -0.1 4,823,928 - +0.5 4,824,111 - PfGW456L13_4308 0.15 +0.4 4,824,545 + PfGW456L13_4308 0.51 -1.0 4,824,650 + PfGW456L13_4308 0.60 +1.5 4,824,650 + PfGW456L13_4308 0.60 -0.6 4,824,650 + PfGW456L13_4308 0.60 -2.0 4,824,650 + PfGW456L13_4308 0.60 -1.0 4,824,651 - PfGW456L13_4308 0.60 +0.1 4,824,651 - PfGW456L13_4308 0.60 -1.7 4,824,651 - PfGW456L13_4308 0.60 +0.4 4,824,651 - PfGW456L13_4308 0.60 -1.0 4,824,651 - PfGW456L13_4308 0.60 -0.3 4,824,668 + PfGW456L13_4308 0.62 -1.1 4,824,668 + PfGW456L13_4308 0.62 -0.7 4,824,669 - PfGW456L13_4308 0.62 -0.6 4,824,669 - PfGW456L13_4308 0.62 +0.4 4,824,669 - PfGW456L13_4308 0.62 -0.8 4,824,800 + PfGW456L13_4308 0.73 -0.5 4,824,800 + PfGW456L13_4308 0.73 +0.9 4,825,139 - +0.6 4,825,623 - -0.3
Or see this region's nucleotide sequence