Experiment: Vancomycin 0.5 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_5000 and PfGW456L13_5001 are separated by 126 nucleotides PfGW456L13_5001 and PfGW456L13_5002 are separated by 125 nucleotides PfGW456L13_5002 and PfGW456L13_5003 are separated by 22 nucleotides PfGW456L13_5003 and PfGW456L13_5004 are separated by 114 nucleotides PfGW456L13_5004 and PfGW456L13_5005 are separated by 17 nucleotides
PfGW456L13_5000 - Histidinol dehydrogenase (EC 1.1.1.23), at 5,578,286 to 5,579,623
_5000
PfGW456L13_5001 - ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) , at 5,579,750 to 5,580,385
_5001
PfGW456L13_5002 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7), at 5,580,511 to 5,581,776
_5002
PfGW456L13_5003 - YrbA protein, at 5,581,799 to 5,582,038
_5003
PfGW456L13_5004 - Uncharacterized protein YrbB, at 5,582,153 to 5,582,437
_5004
PfGW456L13_5005 - Uncharacterized ABC transporter, auxiliary component YrbC, at 5,582,455 to 5,583,108
_5005
Position (kb)
5580
5581
5582 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 5579.623 kb on + strand at 5579.624 kb on - strand at 5579.637 kb on + strand at 5579.637 kb on + strand at 5579.637 kb on + strand at 5579.637 kb on + strand at 5579.638 kb on - strand at 5579.638 kb on - strand at 5579.668 kb on + strand at 5579.668 kb on + strand at 5579.668 kb on + strand at 5579.668 kb on + strand at 5579.668 kb on + strand at 5579.668 kb on + strand at 5579.668 kb on + strand at 5579.669 kb on - strand at 5579.669 kb on - strand at 5579.669 kb on - strand at 5579.706 kb on + strand at 5579.717 kb on + strand at 5579.717 kb on + strand at 5579.718 kb on - strand at 5579.732 kb on + strand at 5579.733 kb on - strand at 5579.908 kb on + strand, within PfGW456L13_5001 at 5579.909 kb on - strand, within PfGW456L13_5001 at 5579.977 kb on - strand, within PfGW456L13_5001 at 5580.018 kb on + strand, within PfGW456L13_5001 at 5580.018 kb on + strand, within PfGW456L13_5001 at 5580.019 kb on - strand, within PfGW456L13_5001 at 5580.138 kb on + strand, within PfGW456L13_5001 at 5580.213 kb on + strand, within PfGW456L13_5001 at 5580.213 kb on + strand, within PfGW456L13_5001 at 5580.213 kb on + strand, within PfGW456L13_5001 at 5580.213 kb on + strand, within PfGW456L13_5001 at 5580.214 kb on - strand, within PfGW456L13_5001 at 5580.214 kb on - strand, within PfGW456L13_5001 at 5580.214 kb on - strand, within PfGW456L13_5001 at 5580.214 kb on - strand, within PfGW456L13_5001 at 5580.214 kb on - strand, within PfGW456L13_5001 at 5580.214 kb on - strand, within PfGW456L13_5001 at 5580.251 kb on + strand, within PfGW456L13_5001 at 5580.251 kb on + strand, within PfGW456L13_5001 at 5580.251 kb on + strand, within PfGW456L13_5001 at 5580.251 kb on + strand, within PfGW456L13_5001 at 5580.251 kb on + strand, within PfGW456L13_5001 at 5580.251 kb on + strand, within PfGW456L13_5001 at 5580.251 kb on + strand, within PfGW456L13_5001 at 5580.251 kb on + strand, within PfGW456L13_5001 at 5580.251 kb on + strand, within PfGW456L13_5001 at 5580.251 kb on + strand, within PfGW456L13_5001 at 5580.252 kb on - strand, within PfGW456L13_5001 at 5580.252 kb on - strand, within PfGW456L13_5001 at 5580.252 kb on - strand, within PfGW456L13_5001 at 5580.252 kb on - strand, within PfGW456L13_5001 at 5580.252 kb on - strand, within PfGW456L13_5001 at 5580.252 kb on - strand, within PfGW456L13_5001 at 5580.252 kb on - strand, within PfGW456L13_5001 at 5580.252 kb on - strand, within PfGW456L13_5001 at 5580.402 kb on + strand at 5580.403 kb on - strand at 5580.410 kb on + strand at 5580.410 kb on + strand at 5580.411 kb on - strand at 5580.411 kb on - strand at 5580.411 kb on - strand at 5580.411 kb on - strand at 5580.411 kb on - strand at 5580.411 kb on - strand at 5580.411 kb on - strand at 5580.492 kb on + strand at 5580.493 kb on - strand at 5580.493 kb on - strand at 5580.493 kb on - strand at 5580.493 kb on - strand at 5580.493 kb on - strand at 5580.500 kb on + strand at 5580.500 kb on + strand at 5580.500 kb on + strand at 5580.501 kb on - strand at 5580.501 kb on - strand at 5580.501 kb on - strand at 5580.501 kb on - strand at 5580.501 kb on - strand at 5580.512 kb on + strand at 5580.512 kb on + strand at 5580.512 kb on + strand at 5581.891 kb on - strand, within PfGW456L13_5003 at 5581.891 kb on - strand, within PfGW456L13_5003 at 5581.891 kb on - strand, within PfGW456L13_5003 at 5581.983 kb on - strand, within PfGW456L13_5003 at 5582.083 kb on - strand at 5582.083 kb on - strand at 5582.083 kb on - strand at 5582.143 kb on + strand at 5582.143 kb on + strand at 5582.143 kb on + strand at 5582.144 kb on - strand at 5582.144 kb on - strand at 5582.144 kb on - strand at 5582.144 kb on - strand at 5582.144 kb on - strand at 5582.144 kb on - strand at 5582.144 kb on - strand at 5582.144 kb on - strand at 5582.144 kb on - strand at 5582.660 kb on + strand, within PfGW456L13_5005 at 5582.673 kb on - strand, within PfGW456L13_5005 at 5582.708 kb on - strand, within PfGW456L13_5005 at 5582.708 kb on - strand, within PfGW456L13_5005 at 5582.708 kb on - strand, within PfGW456L13_5005 at 5582.708 kb on - strand, within PfGW456L13_5005 at 5582.708 kb on - strand, within PfGW456L13_5005 at 5582.716 kb on - strand, within PfGW456L13_5005 at 5582.769 kb on - strand, within PfGW456L13_5005
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.5 mg/ml remove 5,579,623 + -1.6 5,579,624 - +0.0 5,579,637 + -0.5 5,579,637 + +0.4 5,579,637 + -0.5 5,579,637 + +0.2 5,579,638 - -2.0 5,579,638 - +1.6 5,579,668 + +0.0 5,579,668 + -1.3 5,579,668 + -0.1 5,579,668 + +0.7 5,579,668 + -0.5 5,579,668 + -0.8 5,579,668 + +0.0 5,579,669 - +1.2 5,579,669 - -1.6 5,579,669 - +0.0 5,579,706 + -1.6 5,579,717 + +0.6 5,579,717 + +0.3 5,579,718 - +2.0 5,579,732 + -1.0 5,579,733 - +0.5 5,579,908 + PfGW456L13_5001 0.25 +0.7 5,579,909 - PfGW456L13_5001 0.25 -1.6 5,579,977 - PfGW456L13_5001 0.36 +0.9 5,580,018 + PfGW456L13_5001 0.42 +1.6 5,580,018 + PfGW456L13_5001 0.42 -0.1 5,580,019 - PfGW456L13_5001 0.42 -1.3 5,580,138 + PfGW456L13_5001 0.61 -0.2 5,580,213 + PfGW456L13_5001 0.73 -0.6 5,580,213 + PfGW456L13_5001 0.73 -1.8 5,580,213 + PfGW456L13_5001 0.73 -0.2 5,580,213 + PfGW456L13_5001 0.73 +0.0 5,580,214 - PfGW456L13_5001 0.73 -0.0 5,580,214 - PfGW456L13_5001 0.73 +1.7 5,580,214 - PfGW456L13_5001 0.73 +0.3 5,580,214 - PfGW456L13_5001 0.73 +1.8 5,580,214 - PfGW456L13_5001 0.73 +0.4 5,580,214 - PfGW456L13_5001 0.73 +1.3 5,580,251 + PfGW456L13_5001 0.79 +0.4 5,580,251 + PfGW456L13_5001 0.79 +0.0 5,580,251 + PfGW456L13_5001 0.79 +0.4 5,580,251 + PfGW456L13_5001 0.79 -1.9 5,580,251 + PfGW456L13_5001 0.79 -0.7 5,580,251 + PfGW456L13_5001 0.79 -0.6 5,580,251 + PfGW456L13_5001 0.79 +0.4 5,580,251 + PfGW456L13_5001 0.79 -1.2 5,580,251 + PfGW456L13_5001 0.79 +0.5 5,580,251 + PfGW456L13_5001 0.79 -0.6 5,580,252 - PfGW456L13_5001 0.79 +0.1 5,580,252 - PfGW456L13_5001 0.79 +0.0 5,580,252 - PfGW456L13_5001 0.79 -0.2 5,580,252 - PfGW456L13_5001 0.79 -0.2 5,580,252 - PfGW456L13_5001 0.79 +0.2 5,580,252 - PfGW456L13_5001 0.79 -0.1 5,580,252 - PfGW456L13_5001 0.79 -1.3 5,580,252 - PfGW456L13_5001 0.79 +1.2 5,580,402 + +0.8 5,580,403 - -0.5 5,580,410 + -0.6 5,580,410 + +0.3 5,580,411 - +0.2 5,580,411 - -0.2 5,580,411 - +0.8 5,580,411 - -0.6 5,580,411 - +0.8 5,580,411 - +0.5 5,580,411 - -0.0 5,580,492 + -3.6 5,580,493 - +0.8 5,580,493 - -0.4 5,580,493 - -0.7 5,580,493 - +0.8 5,580,493 - +0.3 5,580,500 + -1.5 5,580,500 + -1.3 5,580,500 + +0.6 5,580,501 - -1.3 5,580,501 - +0.5 5,580,501 - -1.1 5,580,501 - -0.3 5,580,501 - -0.4 5,580,512 + +0.0 5,580,512 + -0.1 5,580,512 + -1.2 5,581,891 - PfGW456L13_5003 0.38 +0.0 5,581,891 - PfGW456L13_5003 0.38 -0.2 5,581,891 - PfGW456L13_5003 0.38 -2.6 5,581,983 - PfGW456L13_5003 0.77 +0.0 5,582,083 - -1.0 5,582,083 - -0.1 5,582,083 - -0.4 5,582,143 + -1.1 5,582,143 + -0.9 5,582,143 + -1.8 5,582,144 - +0.4 5,582,144 - +0.4 5,582,144 - -0.3 5,582,144 - +0.4 5,582,144 - -1.3 5,582,144 - +1.3 5,582,144 - -0.4 5,582,144 - +0.6 5,582,144 - +1.7 5,582,660 + PfGW456L13_5005 0.31 +0.0 5,582,673 - PfGW456L13_5005 0.33 -2.9 5,582,708 - PfGW456L13_5005 0.39 -2.4 5,582,708 - PfGW456L13_5005 0.39 -1.3 5,582,708 - PfGW456L13_5005 0.39 -1.2 5,582,708 - PfGW456L13_5005 0.39 +1.0 5,582,708 - PfGW456L13_5005 0.39 -1.6 5,582,716 - PfGW456L13_5005 0.40 -2.9 5,582,769 - PfGW456L13_5005 0.48 -1.8
Or see this region's nucleotide sequence