Experiment: Vancomycin 0.5 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_4639 and PfGW456L13_4640 are separated by 681 nucleotides PfGW456L13_4640 and PfGW456L13_4641 are separated by 107 nucleotides PfGW456L13_4641 and PfGW456L13_4642 are separated by 353 nucleotides PfGW456L13_4642 and PfGW456L13_4643 are separated by 149 nucleotides
PfGW456L13_4639 - Histidine ABC transporter, ATP-binding protein HisP (TC 3.A.1.3.1), at 5,176,947 to 5,177,711
_4639
PfGW456L13_4640 - FIG00955308: hypothetical protein, at 5,178,393 to 5,178,602
_4640
PfGW456L13_4641 - Deoxycytidine triphosphate deaminase (EC 3.5.4.13), at 5,178,710 to 5,179,276
_4641
PfGW456L13_4642 - Cold shock protein CspA, at 5,179,630 to 5,179,839
_4642
PfGW456L13_4643 - Peptide chain release factor RF-3, at 5,179,989 to 5,180,945
_4643
Position (kb)
5178
5179
5180 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 5177.722 kb on + strand at 5177.722 kb on + strand at 5177.814 kb on + strand at 5177.875 kb on - strand at 5177.962 kb on + strand at 5177.962 kb on + strand at 5177.962 kb on + strand at 5177.962 kb on + strand at 5177.962 kb on + strand at 5177.962 kb on + strand at 5177.963 kb on - strand at 5177.963 kb on - strand at 5177.963 kb on - strand at 5177.963 kb on - strand at 5177.966 kb on + strand at 5177.966 kb on + strand at 5177.966 kb on + strand at 5177.967 kb on - strand at 5177.967 kb on - strand at 5177.967 kb on - strand at 5177.967 kb on - strand at 5177.992 kb on + strand at 5177.992 kb on + strand at 5177.992 kb on + strand at 5177.992 kb on + strand at 5177.992 kb on + strand at 5177.992 kb on + strand at 5177.993 kb on - strand at 5177.993 kb on - strand at 5177.998 kb on + strand at 5177.998 kb on + strand at 5177.998 kb on + strand at 5177.999 kb on - strand at 5177.999 kb on - strand at 5178.055 kb on + strand at 5178.056 kb on - strand at 5178.108 kb on + strand at 5178.109 kb on - strand at 5178.109 kb on - strand at 5178.124 kb on + strand at 5178.164 kb on + strand at 5178.175 kb on - strand at 5178.271 kb on + strand at 5178.271 kb on + strand at 5178.271 kb on + strand at 5178.271 kb on + strand at 5178.271 kb on + strand at 5178.272 kb on - strand at 5178.272 kb on - strand at 5178.272 kb on - strand at 5178.272 kb on - strand at 5178.272 kb on - strand at 5178.272 kb on - strand at 5178.272 kb on - strand at 5178.272 kb on - strand at 5178.431 kb on + strand, within PfGW456L13_4640 at 5178.431 kb on + strand, within PfGW456L13_4640 at 5178.449 kb on + strand, within PfGW456L13_4640 at 5178.449 kb on + strand, within PfGW456L13_4640 at 5178.652 kb on + strand at 5178.652 kb on + strand at 5178.652 kb on + strand at 5178.652 kb on + strand at 5178.653 kb on - strand at 5178.653 kb on - strand at 5178.653 kb on - strand at 5178.653 kb on - strand at 5178.653 kb on - strand at 5178.661 kb on + strand at 5178.661 kb on + strand at 5178.662 kb on - strand at 5178.668 kb on + strand at 5178.669 kb on - strand at 5178.669 kb on - strand at 5178.669 kb on - strand at 5178.748 kb on - strand at 5178.988 kb on - strand, within PfGW456L13_4641 at 5179.144 kb on - strand, within PfGW456L13_4641 at 5179.293 kb on - strand at 5179.383 kb on + strand at 5179.383 kb on + strand at 5179.383 kb on + strand at 5179.384 kb on - strand at 5179.384 kb on - strand at 5179.421 kb on + strand at 5179.473 kb on - strand at 5179.513 kb on + strand at 5179.513 kb on + strand at 5179.513 kb on + strand at 5179.521 kb on - strand at 5179.521 kb on - strand at 5179.521 kb on - strand at 5179.521 kb on - strand at 5179.545 kb on + strand at 5179.545 kb on + strand at 5179.607 kb on - strand at 5179.607 kb on - strand at 5179.612 kb on - strand at 5179.625 kb on - strand at 5179.625 kb on - strand at 5179.656 kb on + strand, within PfGW456L13_4642 at 5179.656 kb on + strand, within PfGW456L13_4642 at 5179.826 kb on + strand at 5179.833 kb on + strand at 5179.837 kb on + strand at 5179.837 kb on + strand at 5179.837 kb on + strand at 5179.844 kb on + strand at 5179.853 kb on + strand at 5179.857 kb on - strand at 5179.991 kb on - strand at 5179.991 kb on - strand at 5179.991 kb on - strand at 5180.017 kb on + strand at 5180.107 kb on + strand at 5180.107 kb on + strand at 5180.108 kb on - strand, within PfGW456L13_4643 at 5180.108 kb on - strand, within PfGW456L13_4643 at 5180.210 kb on - strand, within PfGW456L13_4643 at 5180.218 kb on + strand, within PfGW456L13_4643 at 5180.218 kb on + strand, within PfGW456L13_4643 at 5180.218 kb on + strand, within PfGW456L13_4643 at 5180.218 kb on + strand, within PfGW456L13_4643 at 5180.219 kb on - strand, within PfGW456L13_4643 at 5180.219 kb on - strand, within PfGW456L13_4643 at 5180.219 kb on - strand, within PfGW456L13_4643 at 5180.275 kb on + strand, within PfGW456L13_4643 at 5180.275 kb on + strand, within PfGW456L13_4643 at 5180.275 kb on + strand, within PfGW456L13_4643 at 5180.275 kb on + strand, within PfGW456L13_4643
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.5 mg/ml remove 5,177,722 + -0.0 5,177,722 + +1.1 5,177,814 + +0.6 5,177,875 - -1.3 5,177,962 + +0.2 5,177,962 + -0.9 5,177,962 + +0.8 5,177,962 + -0.9 5,177,962 + +0.6 5,177,962 + +0.3 5,177,963 - -1.0 5,177,963 - -0.8 5,177,963 - -1.2 5,177,963 - -1.0 5,177,966 + +0.6 5,177,966 + +0.1 5,177,966 + -1.1 5,177,967 - -0.3 5,177,967 - +0.3 5,177,967 - -0.2 5,177,967 - +0.2 5,177,992 + -0.6 5,177,992 + -1.1 5,177,992 + -1.2 5,177,992 + +0.9 5,177,992 + -0.1 5,177,992 + +0.7 5,177,993 - -1.3 5,177,993 - +0.5 5,177,998 + +0.7 5,177,998 + +0.9 5,177,998 + +1.9 5,177,999 - +1.8 5,177,999 - +0.8 5,178,055 + -0.2 5,178,056 - -0.6 5,178,108 + -0.2 5,178,109 - +0.7 5,178,109 - +0.3 5,178,124 + +0.7 5,178,164 + +1.1 5,178,175 - +0.7 5,178,271 + +0.7 5,178,271 + +0.1 5,178,271 + -1.4 5,178,271 + -0.1 5,178,271 + -0.4 5,178,272 - -0.4 5,178,272 - +0.1 5,178,272 - -0.6 5,178,272 - -0.5 5,178,272 - +1.9 5,178,272 - +0.7 5,178,272 - -0.1 5,178,272 - -1.5 5,178,431 + PfGW456L13_4640 0.18 -0.5 5,178,431 + PfGW456L13_4640 0.18 +1.2 5,178,449 + PfGW456L13_4640 0.27 -0.8 5,178,449 + PfGW456L13_4640 0.27 +1.8 5,178,652 + +1.1 5,178,652 + +0.5 5,178,652 + -0.5 5,178,652 + +0.5 5,178,653 - -0.8 5,178,653 - +0.5 5,178,653 - -0.1 5,178,653 - +1.8 5,178,653 - -1.0 5,178,661 + +1.0 5,178,661 + +1.1 5,178,662 - +1.1 5,178,668 + +1.1 5,178,669 - +0.6 5,178,669 - +0.8 5,178,669 - -0.6 5,178,748 - -0.1 5,178,988 - PfGW456L13_4641 0.49 -1.4 5,179,144 - PfGW456L13_4641 0.77 +0.8 5,179,293 - -0.2 5,179,383 + -0.3 5,179,383 + +0.3 5,179,383 + +0.9 5,179,384 - -0.8 5,179,384 - -2.9 5,179,421 + -1.0 5,179,473 - -0.8 5,179,513 + -1.6 5,179,513 + -1.9 5,179,513 + -1.6 5,179,521 - -1.1 5,179,521 - -1.0 5,179,521 - -1.1 5,179,521 - -0.4 5,179,545 + -3.1 5,179,545 + -3.3 5,179,607 - -0.8 5,179,607 - +0.3 5,179,612 - -2.4 5,179,625 - -2.1 5,179,625 - -0.1 5,179,656 + PfGW456L13_4642 0.12 -2.5 5,179,656 + PfGW456L13_4642 0.12 -0.6 5,179,826 + -1.6 5,179,833 + -0.5 5,179,837 + +0.9 5,179,837 + -0.1 5,179,837 + -1.4 5,179,844 + -1.5 5,179,853 + -0.5 5,179,857 - -0.1 5,179,991 - -0.1 5,179,991 - -0.4 5,179,991 - -0.2 5,180,017 + +0.5 5,180,107 + +2.5 5,180,107 + -0.6 5,180,108 - PfGW456L13_4643 0.12 +0.1 5,180,108 - PfGW456L13_4643 0.12 -0.1 5,180,210 - PfGW456L13_4643 0.23 -1.4 5,180,218 + PfGW456L13_4643 0.24 -0.4 5,180,218 + PfGW456L13_4643 0.24 +0.4 5,180,218 + PfGW456L13_4643 0.24 -0.8 5,180,218 + PfGW456L13_4643 0.24 +1.9 5,180,219 - PfGW456L13_4643 0.24 +1.1 5,180,219 - PfGW456L13_4643 0.24 +1.7 5,180,219 - PfGW456L13_4643 0.24 +1.0 5,180,275 + PfGW456L13_4643 0.30 +0.6 5,180,275 + PfGW456L13_4643 0.30 -0.2 5,180,275 + PfGW456L13_4643 0.30 -2.1 5,180,275 + PfGW456L13_4643 0.30 +0.1
Or see this region's nucleotide sequence