Experiment: Vancomycin 0.5 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_426 and PfGW456L13_427 are separated by 115 nucleotides PfGW456L13_427 and PfGW456L13_428 are separated by 361 nucleotides
PfGW456L13_426 - Osmolarity sensory histidine kinase EnvZ, at 489,691 to 491,004
_426
PfGW456L13_427 - Two-component system response regulator OmpR, at 491,120 to 491,860
_427
PfGW456L13_428 - Transcription accessory protein (S1 RNA-binding domain), at 492,222 to 494,546
_428
Position (kb) 491
492 Strain fitness (log2 ratio) -3
-2
-1
0
1
2 at 490.417 kb on - strand, within PfGW456L13_426 at 490.470 kb on - strand, within PfGW456L13_426 at 490.470 kb on - strand, within PfGW456L13_426 at 490.542 kb on + strand, within PfGW456L13_426 at 490.722 kb on - strand, within PfGW456L13_426 at 490.722 kb on - strand, within PfGW456L13_426 at 490.722 kb on - strand, within PfGW456L13_426 at 490.734 kb on - strand, within PfGW456L13_426 at 490.836 kb on - strand, within PfGW456L13_426 at 490.937 kb on - strand at 490.937 kb on - strand at 491.107 kb on + strand at 491.107 kb on + strand at 491.108 kb on - strand at 491.108 kb on - strand at 491.108 kb on - strand at 491.154 kb on + strand at 491.182 kb on - strand at 491.340 kb on - strand, within PfGW456L13_427 at 491.340 kb on - strand, within PfGW456L13_427 at 491.416 kb on - strand, within PfGW456L13_427 at 491.889 kb on + strand at 491.897 kb on - strand at 491.897 kb on - strand at 491.898 kb on - strand at 491.906 kb on + strand at 491.908 kb on + strand at 491.908 kb on + strand at 491.908 kb on + strand at 491.908 kb on + strand at 491.908 kb on + strand at 491.909 kb on - strand at 491.909 kb on - strand at 491.909 kb on - strand at 491.909 kb on - strand at 491.909 kb on - strand at 491.909 kb on - strand at 491.909 kb on - strand at 491.909 kb on - strand at 491.928 kb on - strand at 491.943 kb on + strand at 491.943 kb on + strand at 492.007 kb on + strand at 492.007 kb on + strand at 492.007 kb on + strand at 492.008 kb on - strand at 492.008 kb on - strand at 492.008 kb on - strand at 492.008 kb on - strand at 492.008 kb on - strand at 492.009 kb on + strand at 492.009 kb on + strand at 492.009 kb on + strand at 492.009 kb on + strand at 492.009 kb on + strand at 492.009 kb on + strand at 492.010 kb on - strand at 492.010 kb on - strand at 492.010 kb on - strand at 492.010 kb on - strand at 492.010 kb on - strand at 492.047 kb on + strand at 492.047 kb on + strand at 492.047 kb on + strand at 492.047 kb on + strand at 492.047 kb on + strand at 492.047 kb on + strand at 492.048 kb on - strand at 492.050 kb on + strand at 492.050 kb on + strand at 492.050 kb on + strand at 492.050 kb on + strand at 492.050 kb on + strand at 492.051 kb on - strand at 492.087 kb on + strand at 492.087 kb on + strand at 492.087 kb on + strand at 492.087 kb on + strand at 492.087 kb on + strand at 492.088 kb on - strand at 492.088 kb on - strand at 492.088 kb on - strand at 492.088 kb on - strand at 492.175 kb on + strand at 492.176 kb on - strand at 492.176 kb on - strand at 492.222 kb on - strand at 492.263 kb on - strand at 492.263 kb on - strand at 492.311 kb on + strand at 492.458 kb on + strand, within PfGW456L13_428 at 492.458 kb on + strand, within PfGW456L13_428 at 492.526 kb on - strand, within PfGW456L13_428 at 492.534 kb on + strand, within PfGW456L13_428 at 492.535 kb on - strand, within PfGW456L13_428 at 492.535 kb on - strand, within PfGW456L13_428 at 492.705 kb on + strand, within PfGW456L13_428 at 492.705 kb on + strand, within PfGW456L13_428 at 492.705 kb on + strand, within PfGW456L13_428 at 492.705 kb on + strand, within PfGW456L13_428 at 492.706 kb on - strand, within PfGW456L13_428 at 492.706 kb on - strand, within PfGW456L13_428 at 492.706 kb on - strand, within PfGW456L13_428 at 492.706 kb on - strand, within PfGW456L13_428 at 492.706 kb on - strand, within PfGW456L13_428 at 492.706 kb on - strand, within PfGW456L13_428 at 492.762 kb on + strand, within PfGW456L13_428 at 492.762 kb on + strand, within PfGW456L13_428 at 492.763 kb on - strand, within PfGW456L13_428
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.5 mg/ml remove 490,417 - PfGW456L13_426 0.55 -0.9 490,470 - PfGW456L13_426 0.59 -0.4 490,470 - PfGW456L13_426 0.59 -1.3 490,542 + PfGW456L13_426 0.65 -2.4 490,722 - PfGW456L13_426 0.78 -0.2 490,722 - PfGW456L13_426 0.78 -0.7 490,722 - PfGW456L13_426 0.78 +0.4 490,734 - PfGW456L13_426 0.79 -1.6 490,836 - PfGW456L13_426 0.87 +0.7 490,937 - +0.3 490,937 - -0.3 491,107 + -0.5 491,107 + -3.0 491,108 - -1.2 491,108 - -0.1 491,108 - -0.5 491,154 + -2.0 491,182 - -0.1 491,340 - PfGW456L13_427 0.30 -0.4 491,340 - PfGW456L13_427 0.30 -1.2 491,416 - PfGW456L13_427 0.40 -2.0 491,889 + -1.2 491,897 - +0.8 491,897 - +0.8 491,898 - -0.2 491,906 + +0.1 491,908 + -1.4 491,908 + -0.2 491,908 + -1.6 491,908 + -0.4 491,908 + -0.7 491,909 - -0.9 491,909 - -0.5 491,909 - +0.9 491,909 - +0.6 491,909 - -0.0 491,909 - -1.0 491,909 - +0.8 491,909 - +0.3 491,928 - -1.4 491,943 + -0.7 491,943 + +0.3 492,007 + +0.9 492,007 + -0.3 492,007 + -1.7 492,008 - +0.5 492,008 - -0.4 492,008 - +0.6 492,008 - -0.6 492,008 - -0.0 492,009 + -1.8 492,009 + -0.4 492,009 + -0.9 492,009 + -0.6 492,009 + -0.8 492,009 + -0.2 492,010 - +0.1 492,010 - +2.0 492,010 - +0.4 492,010 - +1.9 492,010 - -0.6 492,047 + +0.3 492,047 + -1.7 492,047 + -0.5 492,047 + -1.2 492,047 + -1.6 492,047 + -0.1 492,048 - -0.5 492,050 + -1.1 492,050 + -0.2 492,050 + +1.7 492,050 + -0.9 492,050 + +0.7 492,051 - -0.2 492,087 + +1.1 492,087 + -1.0 492,087 + +0.2 492,087 + -0.7 492,087 + -0.1 492,088 - -0.6 492,088 - -0.7 492,088 - +0.6 492,088 - -0.2 492,175 + +0.9 492,176 - +0.2 492,176 - -1.4 492,222 - -1.1 492,263 - -1.3 492,263 - -1.1 492,311 + -0.8 492,458 + PfGW456L13_428 0.10 -0.2 492,458 + PfGW456L13_428 0.10 -0.2 492,526 - PfGW456L13_428 0.13 +0.8 492,534 + PfGW456L13_428 0.13 -0.3 492,535 - PfGW456L13_428 0.13 -0.9 492,535 - PfGW456L13_428 0.13 +0.2 492,705 + PfGW456L13_428 0.21 -1.4 492,705 + PfGW456L13_428 0.21 -1.1 492,705 + PfGW456L13_428 0.21 -1.3 492,705 + PfGW456L13_428 0.21 -0.9 492,706 - PfGW456L13_428 0.21 -0.3 492,706 - PfGW456L13_428 0.21 +0.1 492,706 - PfGW456L13_428 0.21 -0.3 492,706 - PfGW456L13_428 0.21 -1.4 492,706 - PfGW456L13_428 0.21 -0.5 492,706 - PfGW456L13_428 0.21 -2.1 492,762 + PfGW456L13_428 0.23 -1.6 492,762 + PfGW456L13_428 0.23 -0.5 492,763 - PfGW456L13_428 0.23 +0.5
Or see this region's nucleotide sequence