Experiment: Vancomycin 0.5 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_4048 and PfGW456L13_4049 are separated by 255 nucleotides PfGW456L13_4049 and PfGW456L13_4050 are separated by 126 nucleotides PfGW456L13_4050 and PfGW456L13_4051 are separated by 191 nucleotides
PfGW456L13_4048 - Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290), at 4,543,963 to 4,545,105
_4048
PfGW456L13_4049 - Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps, at 4,545,361 to 4,546,755
_4049
PfGW456L13_4050 - tRNA 5-methylaminomethyl-2-thiouridine synthase TusA, at 4,546,882 to 4,547,133
_4050
PfGW456L13_4051 - LSU rRNA 2'-O-methyl-C2498 methyltransferase RlmM, at 4,547,325 to 4,548,398
_4051
Position (kb)
4545
4546
4547 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 4544.814 kb on - strand, within PfGW456L13_4048 at 4544.860 kb on - strand, within PfGW456L13_4048 at 4544.917 kb on - strand, within PfGW456L13_4048 at 4545.135 kb on - strand at 4545.157 kb on + strand at 4545.158 kb on - strand at 4545.158 kb on - strand at 4545.251 kb on + strand at 4545.252 kb on - strand at 4545.252 kb on - strand at 4545.272 kb on - strand at 4545.277 kb on + strand at 4545.278 kb on - strand at 4545.316 kb on + strand at 4545.316 kb on + strand at 4545.316 kb on + strand at 4545.568 kb on + strand, within PfGW456L13_4049 at 4545.568 kb on + strand, within PfGW456L13_4049 at 4545.782 kb on - strand, within PfGW456L13_4049 at 4545.823 kb on + strand, within PfGW456L13_4049 at 4545.823 kb on + strand, within PfGW456L13_4049 at 4545.824 kb on - strand, within PfGW456L13_4049 at 4545.824 kb on - strand, within PfGW456L13_4049 at 4545.826 kb on + strand, within PfGW456L13_4049 at 4545.826 kb on + strand at 4545.826 kb on + strand at 4545.826 kb on + strand, within PfGW456L13_4049 at 4545.826 kb on + strand, within PfGW456L13_4049 at 4545.826 kb on + strand, within PfGW456L13_4049 at 4545.826 kb on + strand, within PfGW456L13_4049 at 4545.826 kb on + strand, within PfGW456L13_4049 at 4545.827 kb on - strand at 4545.842 kb on - strand, within PfGW456L13_4049 at 4545.842 kb on - strand, within PfGW456L13_4049 at 4545.919 kb on + strand, within PfGW456L13_4049 at 4545.919 kb on + strand, within PfGW456L13_4049 at 4545.920 kb on - strand, within PfGW456L13_4049 at 4545.920 kb on - strand, within PfGW456L13_4049 at 4545.920 kb on - strand, within PfGW456L13_4049 at 4545.931 kb on + strand, within PfGW456L13_4049 at 4545.931 kb on + strand, within PfGW456L13_4049 at 4545.931 kb on + strand, within PfGW456L13_4049 at 4545.932 kb on - strand, within PfGW456L13_4049 at 4546.045 kb on + strand, within PfGW456L13_4049 at 4546.045 kb on + strand, within PfGW456L13_4049 at 4546.045 kb on + strand, within PfGW456L13_4049 at 4546.045 kb on + strand, within PfGW456L13_4049 at 4546.046 kb on - strand, within PfGW456L13_4049 at 4546.046 kb on - strand, within PfGW456L13_4049 at 4546.231 kb on - strand, within PfGW456L13_4049 at 4546.258 kb on + strand, within PfGW456L13_4049 at 4546.410 kb on + strand, within PfGW456L13_4049 at 4546.411 kb on - strand, within PfGW456L13_4049 at 4546.411 kb on - strand, within PfGW456L13_4049 at 4546.423 kb on + strand, within PfGW456L13_4049 at 4546.423 kb on + strand, within PfGW456L13_4049 at 4546.423 kb on + strand, within PfGW456L13_4049 at 4546.423 kb on + strand, within PfGW456L13_4049 at 4546.424 kb on - strand, within PfGW456L13_4049 at 4546.471 kb on + strand, within PfGW456L13_4049 at 4546.483 kb on + strand, within PfGW456L13_4049 at 4546.483 kb on + strand, within PfGW456L13_4049 at 4546.865 kb on + strand at 4546.865 kb on + strand at 4546.865 kb on + strand at 4546.866 kb on - strand at 4547.179 kb on + strand at 4547.179 kb on + strand at 4547.180 kb on - strand at 4547.212 kb on + strand at 4547.213 kb on - strand at 4547.213 kb on - strand at 4547.213 kb on - strand at 4547.213 kb on - strand at 4547.213 kb on - strand at 4547.393 kb on - strand at 4547.479 kb on + strand, within PfGW456L13_4051 at 4547.480 kb on - strand, within PfGW456L13_4051
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.5 mg/ml remove 4,544,814 - PfGW456L13_4048 0.74 -0.8 4,544,860 - PfGW456L13_4048 0.78 -0.8 4,544,917 - PfGW456L13_4048 0.83 +0.8 4,545,135 - +0.2 4,545,157 + -0.9 4,545,158 - +0.2 4,545,158 - +0.5 4,545,251 + -0.1 4,545,252 - -0.5 4,545,252 - -1.8 4,545,272 - +0.5 4,545,277 + +0.1 4,545,278 - +1.2 4,545,316 + +0.6 4,545,316 + +0.8 4,545,316 + -0.2 4,545,568 + PfGW456L13_4049 0.15 +1.1 4,545,568 + PfGW456L13_4049 0.15 +0.0 4,545,782 - PfGW456L13_4049 0.30 +0.5 4,545,823 + PfGW456L13_4049 0.33 -0.0 4,545,823 + PfGW456L13_4049 0.33 +0.0 4,545,824 - PfGW456L13_4049 0.33 +0.2 4,545,824 - PfGW456L13_4049 0.33 -1.2 4,545,826 + PfGW456L13_4049 0.33 -0.9 4,545,826 + -0.8 4,545,826 + +1.8 4,545,826 + PfGW456L13_4049 0.33 -1.4 4,545,826 + PfGW456L13_4049 0.33 -2.1 4,545,826 + PfGW456L13_4049 0.33 +1.5 4,545,826 + PfGW456L13_4049 0.33 -1.6 4,545,826 + PfGW456L13_4049 0.33 -0.7 4,545,827 - -1.2 4,545,842 - PfGW456L13_4049 0.34 +0.7 4,545,842 - PfGW456L13_4049 0.34 -1.5 4,545,919 + PfGW456L13_4049 0.40 -0.2 4,545,919 + PfGW456L13_4049 0.40 -0.5 4,545,920 - PfGW456L13_4049 0.40 -0.5 4,545,920 - PfGW456L13_4049 0.40 -0.2 4,545,920 - PfGW456L13_4049 0.40 +1.2 4,545,931 + PfGW456L13_4049 0.41 -0.9 4,545,931 + PfGW456L13_4049 0.41 -0.0 4,545,931 + PfGW456L13_4049 0.41 +1.2 4,545,932 - PfGW456L13_4049 0.41 -0.4 4,546,045 + PfGW456L13_4049 0.49 -0.3 4,546,045 + PfGW456L13_4049 0.49 -0.4 4,546,045 + PfGW456L13_4049 0.49 +0.4 4,546,045 + PfGW456L13_4049 0.49 -0.3 4,546,046 - PfGW456L13_4049 0.49 -2.2 4,546,046 - PfGW456L13_4049 0.49 -1.3 4,546,231 - PfGW456L13_4049 0.62 -0.9 4,546,258 + PfGW456L13_4049 0.64 -1.0 4,546,410 + PfGW456L13_4049 0.75 -1.2 4,546,411 - PfGW456L13_4049 0.75 -1.2 4,546,411 - PfGW456L13_4049 0.75 -0.5 4,546,423 + PfGW456L13_4049 0.76 +0.3 4,546,423 + PfGW456L13_4049 0.76 +0.4 4,546,423 + PfGW456L13_4049 0.76 +0.5 4,546,423 + PfGW456L13_4049 0.76 +1.1 4,546,424 - PfGW456L13_4049 0.76 -1.1 4,546,471 + PfGW456L13_4049 0.80 -0.8 4,546,483 + PfGW456L13_4049 0.80 -3.1 4,546,483 + PfGW456L13_4049 0.80 +0.6 4,546,865 + +0.8 4,546,865 + -0.1 4,546,865 + +0.2 4,546,866 - +0.9 4,547,179 + -1.6 4,547,179 + -0.4 4,547,180 - +0.3 4,547,212 + +0.3 4,547,213 - +0.1 4,547,213 - -2.2 4,547,213 - +0.1 4,547,213 - -0.8 4,547,213 - -2.6 4,547,393 - +0.8 4,547,479 + PfGW456L13_4051 0.14 -0.7 4,547,480 - PfGW456L13_4051 0.14 +0.5
Or see this region's nucleotide sequence