Experiment: Vancomycin 0.5 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_327 and PfGW456L13_328 are separated by 319 nucleotides PfGW456L13_328 and PfGW456L13_329 overlap by 4 nucleotides PfGW456L13_329 and PfGW456L13_330 are separated by 107 nucleotides
PfGW456L13_327 - hypothetical protein, at 383,249 to 383,368
_327
PfGW456L13_328 - Conserved hypothetical protein (perhaps related to histidine degradation), at 383,688 to 384,257
_328
PfGW456L13_329 - Histidine utilization repressor, at 384,254 to 385,003
_329
PfGW456L13_330 - Formiminoglutamic iminohydrolase (EC 3.5.3.13) <small>(from data)</small>, at 385,111 to 386,475
_330
Position (kb) 384
385
386 Strain fitness (log2 ratio) -4
-3
-2
-1
0
1
2 at 383.306 kb on + strand, within PfGW456L13_327 at 383.306 kb on + strand, within PfGW456L13_327 at 383.307 kb on - strand, within PfGW456L13_327 at 383.312 kb on + strand, within PfGW456L13_327 at 383.313 kb on - strand, within PfGW456L13_327 at 383.320 kb on + strand, within PfGW456L13_327 at 383.321 kb on - strand, within PfGW456L13_327 at 383.326 kb on + strand, within PfGW456L13_327 at 383.326 kb on + strand, within PfGW456L13_327 at 383.330 kb on + strand, within PfGW456L13_327 at 383.331 kb on - strand, within PfGW456L13_327 at 383.472 kb on - strand at 383.620 kb on + strand at 383.620 kb on + strand at 383.620 kb on + strand at 383.620 kb on + strand at 383.621 kb on - strand at 383.621 kb on - strand at 383.621 kb on - strand at 383.621 kb on - strand at 383.621 kb on - strand at 383.651 kb on + strand at 383.673 kb on + strand at 383.673 kb on + strand at 383.674 kb on - strand at 383.674 kb on - strand at 383.686 kb on + strand at 383.686 kb on + strand at 383.686 kb on + strand at 383.686 kb on + strand at 383.686 kb on + strand at 383.686 kb on + strand at 383.686 kb on + strand at 383.687 kb on - strand at 383.687 kb on - strand at 383.687 kb on - strand at 383.831 kb on + strand, within PfGW456L13_328 at 383.920 kb on + strand, within PfGW456L13_328 at 383.920 kb on + strand, within PfGW456L13_328 at 383.920 kb on + strand, within PfGW456L13_328 at 383.921 kb on - strand, within PfGW456L13_328 at 384.237 kb on + strand at 384.238 kb on - strand at 384.247 kb on - strand at 384.247 kb on - strand at 384.259 kb on + strand at 384.259 kb on + strand at 384.259 kb on + strand at 384.259 kb on + strand at 384.260 kb on - strand at 384.260 kb on - strand at 384.465 kb on + strand, within PfGW456L13_329 at 384.465 kb on + strand, within PfGW456L13_329 at 384.504 kb on + strand, within PfGW456L13_329 at 384.725 kb on + strand, within PfGW456L13_329 at 384.725 kb on + strand, within PfGW456L13_329 at 384.940 kb on - strand at 385.008 kb on - strand at 385.008 kb on - strand at 385.022 kb on + strand at 385.022 kb on + strand at 385.022 kb on + strand at 385.025 kb on + strand at 385.025 kb on + strand at 385.025 kb on + strand at 385.025 kb on + strand at 385.025 kb on + strand at 385.025 kb on + strand at 385.026 kb on - strand at 385.026 kb on - strand at 385.026 kb on - strand at 385.026 kb on - strand at 385.026 kb on - strand at 385.036 kb on - strand at 385.071 kb on + strand at 385.071 kb on + strand at 385.072 kb on - strand at 385.072 kb on - strand at 385.072 kb on - strand at 385.073 kb on + strand at 385.073 kb on + strand at 385.073 kb on + strand at 385.073 kb on + strand at 385.074 kb on - strand at 385.074 kb on - strand at 385.074 kb on - strand at 385.074 kb on - strand at 385.074 kb on - strand at 385.074 kb on - strand at 385.074 kb on - strand at 385.077 kb on + strand at 385.077 kb on + strand at 385.077 kb on + strand at 385.078 kb on - strand at 385.078 kb on - strand at 385.078 kb on - strand at 385.078 kb on - strand at 385.078 kb on - strand at 385.146 kb on + strand at 385.147 kb on - strand at 385.166 kb on + strand at 385.166 kb on + strand at 385.166 kb on + strand at 385.166 kb on + strand at 385.166 kb on + strand at 385.166 kb on + strand at 385.166 kb on + strand at 385.166 kb on + strand at 385.167 kb on - strand at 385.167 kb on - strand at 385.203 kb on + strand at 385.274 kb on + strand, within PfGW456L13_330 at 385.274 kb on + strand, within PfGW456L13_330 at 385.275 kb on - strand, within PfGW456L13_330 at 385.275 kb on - strand, within PfGW456L13_330 at 385.275 kb on - strand, within PfGW456L13_330 at 385.366 kb on + strand, within PfGW456L13_330 at 385.423 kb on + strand, within PfGW456L13_330 at 385.423 kb on + strand, within PfGW456L13_330 at 385.423 kb on + strand, within PfGW456L13_330 at 385.423 kb on + strand, within PfGW456L13_330 at 385.423 kb on + strand, within PfGW456L13_330 at 385.423 kb on + strand, within PfGW456L13_330 at 385.423 kb on + strand, within PfGW456L13_330 at 385.424 kb on - strand, within PfGW456L13_330 at 385.424 kb on - strand, within PfGW456L13_330 at 385.424 kb on - strand, within PfGW456L13_330 at 385.424 kb on - strand, within PfGW456L13_330 at 385.471 kb on + strand, within PfGW456L13_330 at 385.472 kb on - strand, within PfGW456L13_330 at 385.475 kb on + strand, within PfGW456L13_330 at 385.475 kb on + strand, within PfGW456L13_330 at 385.476 kb on - strand, within PfGW456L13_330 at 385.476 kb on - strand, within PfGW456L13_330 at 385.476 kb on - strand, within PfGW456L13_330 at 385.476 kb on - strand, within PfGW456L13_330 at 385.476 kb on - strand, within PfGW456L13_330 at 385.476 kb on - strand, within PfGW456L13_330 at 385.476 kb on - strand, within PfGW456L13_330 at 385.502 kb on - strand, within PfGW456L13_330 at 385.531 kb on - strand, within PfGW456L13_330 at 385.531 kb on - strand, within PfGW456L13_330 at 385.585 kb on + strand, within PfGW456L13_330 at 385.586 kb on - strand, within PfGW456L13_330 at 385.586 kb on - strand, within PfGW456L13_330 at 385.586 kb on - strand, within PfGW456L13_330 at 385.657 kb on + strand, within PfGW456L13_330 at 385.879 kb on + strand, within PfGW456L13_330 at 385.879 kb on + strand, within PfGW456L13_330
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.5 mg/ml remove 383,306 + PfGW456L13_327 0.47 +0.2 383,306 + PfGW456L13_327 0.47 -0.4 383,307 - PfGW456L13_327 0.48 -0.6 383,312 + PfGW456L13_327 0.53 -0.7 383,313 - PfGW456L13_327 0.53 -0.8 383,320 + PfGW456L13_327 0.59 -0.2 383,321 - PfGW456L13_327 0.60 -0.6 383,326 + PfGW456L13_327 0.64 -0.5 383,326 + PfGW456L13_327 0.64 +0.8 383,330 + PfGW456L13_327 0.68 +0.4 383,331 - PfGW456L13_327 0.68 -1.0 383,472 - +0.2 383,620 + +1.5 383,620 + -0.6 383,620 + +0.1 383,620 + -0.4 383,621 - -0.6 383,621 - +0.1 383,621 - +0.4 383,621 - +0.4 383,621 - +0.4 383,651 + +0.2 383,673 + +0.4 383,673 + +0.4 383,674 - +0.8 383,674 - +0.4 383,686 + -1.5 383,686 + +1.5 383,686 + -0.6 383,686 + -0.4 383,686 + -0.6 383,686 + +1.1 383,686 + -0.1 383,687 - +0.7 383,687 - -0.2 383,687 - +0.7 383,831 + PfGW456L13_328 0.25 -2.3 383,920 + PfGW456L13_328 0.41 -0.2 383,920 + PfGW456L13_328 0.41 -0.1 383,920 + PfGW456L13_328 0.41 +0.2 383,921 - PfGW456L13_328 0.41 +1.0 384,237 + +0.1 384,238 - +0.1 384,247 - +0.9 384,247 - +0.5 384,259 + +0.2 384,259 + +0.9 384,259 + -1.3 384,259 + -0.0 384,260 - +0.0 384,260 - -1.2 384,465 + PfGW456L13_329 0.28 -2.7 384,465 + PfGW456L13_329 0.28 -1.6 384,504 + PfGW456L13_329 0.33 -1.0 384,725 + PfGW456L13_329 0.63 -1.8 384,725 + PfGW456L13_329 0.63 -1.6 384,940 - -1.3 385,008 - -4.2 385,008 - -3.0 385,022 + +0.3 385,022 + -2.3 385,022 + -1.6 385,025 + -0.3 385,025 + -0.3 385,025 + -2.3 385,025 + +1.0 385,025 + -3.0 385,025 + -1.5 385,026 - -1.1 385,026 - -0.5 385,026 - +0.8 385,026 - +0.4 385,026 - -1.0 385,036 - -0.6 385,071 + +0.6 385,071 + +0.0 385,072 - +0.1 385,072 - -0.7 385,072 - -1.5 385,073 + +0.5 385,073 + +0.8 385,073 + +0.7 385,073 + -0.1 385,074 - -0.5 385,074 - +0.1 385,074 - +0.7 385,074 - +1.2 385,074 - -1.0 385,074 - -0.1 385,074 - -0.9 385,077 + +1.1 385,077 + -1.7 385,077 + +0.3 385,078 - -1.5 385,078 - -0.7 385,078 - +0.2 385,078 - -0.6 385,078 - -0.6 385,146 + -0.4 385,147 - -0.9 385,166 + +0.1 385,166 + +0.6 385,166 + -1.8 385,166 + -0.1 385,166 + +0.1 385,166 + -1.1 385,166 + -0.4 385,166 + +0.2 385,167 - +0.8 385,167 - +1.0 385,203 + -0.6 385,274 + PfGW456L13_330 0.12 -0.1 385,274 + PfGW456L13_330 0.12 -1.2 385,275 - PfGW456L13_330 0.12 -0.2 385,275 - PfGW456L13_330 0.12 -0.0 385,275 - PfGW456L13_330 0.12 -0.2 385,366 + PfGW456L13_330 0.19 -0.9 385,423 + PfGW456L13_330 0.23 +0.2 385,423 + PfGW456L13_330 0.23 -0.0 385,423 + PfGW456L13_330 0.23 -1.7 385,423 + PfGW456L13_330 0.23 +0.2 385,423 + PfGW456L13_330 0.23 +1.9 385,423 + PfGW456L13_330 0.23 -0.3 385,423 + PfGW456L13_330 0.23 -0.8 385,424 - PfGW456L13_330 0.23 -1.2 385,424 - PfGW456L13_330 0.23 -0.1 385,424 - PfGW456L13_330 0.23 -0.6 385,424 - PfGW456L13_330 0.23 -0.3 385,471 + PfGW456L13_330 0.26 +0.3 385,472 - PfGW456L13_330 0.26 -2.3 385,475 + PfGW456L13_330 0.27 -0.6 385,475 + PfGW456L13_330 0.27 +0.4 385,476 - PfGW456L13_330 0.27 -0.1 385,476 - PfGW456L13_330 0.27 -0.2 385,476 - PfGW456L13_330 0.27 -1.2 385,476 - PfGW456L13_330 0.27 -0.4 385,476 - PfGW456L13_330 0.27 +0.3 385,476 - PfGW456L13_330 0.27 -0.2 385,476 - PfGW456L13_330 0.27 -0.5 385,502 - PfGW456L13_330 0.29 -0.1 385,531 - PfGW456L13_330 0.31 -1.0 385,531 - PfGW456L13_330 0.31 -0.3 385,585 + PfGW456L13_330 0.35 +0.4 385,586 - PfGW456L13_330 0.35 -0.3 385,586 - PfGW456L13_330 0.35 +0.0 385,586 - PfGW456L13_330 0.35 +0.1 385,657 + PfGW456L13_330 0.40 -1.5 385,879 + PfGW456L13_330 0.56 +1.3 385,879 + PfGW456L13_330 0.56 -0.3
Or see this region's nucleotide sequence