Experiment: Vancomycin 0.5 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_2884 and PfGW456L13_2885 are separated by 154 nucleotides PfGW456L13_2885 and PfGW456L13_2886 are separated by 2 nucleotides
PfGW456L13_2884 - Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1), at 3,213,812 to 3,214,288
_2884
PfGW456L13_2885 - BarA-associated response regulator UvrY (= GacA = SirA), at 3,214,443 to 3,215,027
_2885
PfGW456L13_2886 - Excinuclease ABC subunit C, at 3,215,030 to 3,216,853
_2886
Position (kb)
3214
3215
3216 Strain fitness (log2 ratio)
-3
-2
-1
0
1 at 3213.498 kb on - strand at 3213.517 kb on - strand at 3213.534 kb on - strand at 3213.610 kb on + strand at 3213.611 kb on - strand at 3213.611 kb on - strand at 3213.656 kb on + strand at 3213.657 kb on - strand at 3213.657 kb on - strand at 3213.657 kb on - strand at 3213.659 kb on + strand at 3213.659 kb on + strand at 3213.660 kb on - strand at 3213.660 kb on - strand at 3213.716 kb on + strand at 3213.761 kb on + strand at 3213.762 kb on - strand at 3213.877 kb on + strand, within PfGW456L13_2884 at 3213.894 kb on - strand, within PfGW456L13_2884 at 3213.896 kb on + strand, within PfGW456L13_2884 at 3213.896 kb on + strand, within PfGW456L13_2884 at 3213.897 kb on - strand, within PfGW456L13_2884 at 3213.897 kb on - strand, within PfGW456L13_2884 at 3213.897 kb on - strand, within PfGW456L13_2884 at 3213.996 kb on - strand, within PfGW456L13_2884 at 3213.996 kb on - strand, within PfGW456L13_2884 at 3214.028 kb on + strand, within PfGW456L13_2884 at 3214.028 kb on + strand at 3214.028 kb on + strand, within PfGW456L13_2884 at 3214.028 kb on + strand, within PfGW456L13_2884 at 3214.028 kb on + strand, within PfGW456L13_2884 at 3214.028 kb on + strand, within PfGW456L13_2884 at 3214.028 kb on + strand, within PfGW456L13_2884 at 3214.028 kb on + strand, within PfGW456L13_2884 at 3214.028 kb on + strand, within PfGW456L13_2884 at 3214.028 kb on + strand, within PfGW456L13_2884 at 3214.028 kb on + strand, within PfGW456L13_2884 at 3214.028 kb on + strand, within PfGW456L13_2884 at 3214.028 kb on + strand, within PfGW456L13_2884 at 3214.029 kb on - strand, within PfGW456L13_2884 at 3214.029 kb on - strand, within PfGW456L13_2884 at 3214.029 kb on - strand, within PfGW456L13_2884 at 3214.029 kb on - strand, within PfGW456L13_2884 at 3214.029 kb on - strand, within PfGW456L13_2884 at 3214.029 kb on - strand, within PfGW456L13_2884 at 3214.029 kb on - strand, within PfGW456L13_2884 at 3214.029 kb on - strand, within PfGW456L13_2884 at 3214.029 kb on - strand, within PfGW456L13_2884 at 3214.029 kb on - strand, within PfGW456L13_2884 at 3214.029 kb on - strand, within PfGW456L13_2884 at 3214.029 kb on - strand, within PfGW456L13_2884 at 3214.029 kb on - strand, within PfGW456L13_2884 at 3214.029 kb on - strand, within PfGW456L13_2884 at 3214.029 kb on - strand, within PfGW456L13_2884 at 3214.029 kb on - strand, within PfGW456L13_2884 at 3214.176 kb on - strand, within PfGW456L13_2884 at 3214.300 kb on + strand at 3214.300 kb on + strand at 3214.391 kb on + strand at 3214.392 kb on - strand at 3214.392 kb on - strand at 3214.399 kb on + strand at 3214.399 kb on + strand at 3214.399 kb on + strand at 3214.399 kb on + strand at 3214.399 kb on + strand at 3214.399 kb on + strand at 3214.399 kb on + strand at 3214.399 kb on + strand at 3214.400 kb on - strand at 3214.400 kb on - strand at 3214.400 kb on - strand at 3214.400 kb on - strand at 3214.400 kb on - strand at 3214.400 kb on - strand at 3214.400 kb on - strand at 3214.402 kb on + strand at 3214.402 kb on + strand at 3214.403 kb on - strand at 3214.428 kb on - strand at 3214.428 kb on - strand at 3214.436 kb on + strand at 3214.437 kb on - strand at 3214.437 kb on - strand at 3214.471 kb on + strand at 3214.471 kb on + strand at 3214.591 kb on + strand, within PfGW456L13_2885 at 3214.686 kb on + strand, within PfGW456L13_2885 at 3214.738 kb on + strand, within PfGW456L13_2885 at 3214.738 kb on + strand, within PfGW456L13_2885 at 3214.738 kb on + strand, within PfGW456L13_2885 at 3214.739 kb on - strand, within PfGW456L13_2885 at 3214.739 kb on - strand, within PfGW456L13_2885 at 3214.739 kb on - strand, within PfGW456L13_2885 at 3214.755 kb on + strand, within PfGW456L13_2885 at 3214.755 kb on + strand, within PfGW456L13_2885 at 3214.755 kb on + strand, within PfGW456L13_2885 at 3214.755 kb on + strand, within PfGW456L13_2885 at 3214.755 kb on + strand, within PfGW456L13_2885 at 3214.756 kb on - strand, within PfGW456L13_2885 at 3214.756 kb on - strand, within PfGW456L13_2885 at 3214.756 kb on - strand, within PfGW456L13_2885 at 3214.756 kb on - strand, within PfGW456L13_2885 at 3214.756 kb on - strand, within PfGW456L13_2885 at 3214.882 kb on + strand, within PfGW456L13_2885 at 3214.882 kb on + strand, within PfGW456L13_2885 at 3214.882 kb on + strand, within PfGW456L13_2885 at 3214.882 kb on + strand, within PfGW456L13_2885 at 3214.883 kb on - strand, within PfGW456L13_2885 at 3214.883 kb on - strand, within PfGW456L13_2885 at 3214.933 kb on - strand, within PfGW456L13_2885 at 3214.933 kb on - strand, within PfGW456L13_2885 at 3215.123 kb on + strand at 3215.124 kb on - strand at 3215.166 kb on - strand at 3215.303 kb on + strand, within PfGW456L13_2886 at 3215.303 kb on + strand, within PfGW456L13_2886 at 3215.303 kb on + strand, within PfGW456L13_2886 at 3215.304 kb on - strand, within PfGW456L13_2886 at 3215.306 kb on - strand, within PfGW456L13_2886 at 3215.306 kb on - strand, within PfGW456L13_2886 at 3215.306 kb on - strand, within PfGW456L13_2886 at 3215.306 kb on - strand, within PfGW456L13_2886 at 3215.327 kb on - strand, within PfGW456L13_2886 at 3215.327 kb on - strand, within PfGW456L13_2886 at 3215.339 kb on + strand at 3215.339 kb on + strand, within PfGW456L13_2886 at 3215.340 kb on - strand, within PfGW456L13_2886 at 3215.340 kb on - strand, within PfGW456L13_2886 at 3215.340 kb on - strand, within PfGW456L13_2886 at 3215.411 kb on + strand, within PfGW456L13_2886 at 3215.411 kb on + strand, within PfGW456L13_2886 at 3215.412 kb on - strand, within PfGW456L13_2886 at 3215.501 kb on + strand, within PfGW456L13_2886 at 3215.501 kb on + strand, within PfGW456L13_2886 at 3215.501 kb on + strand, within PfGW456L13_2886 at 3215.501 kb on + strand, within PfGW456L13_2886 at 3215.501 kb on + strand, within PfGW456L13_2886 at 3215.501 kb on + strand, within PfGW456L13_2886 at 3215.502 kb on - strand, within PfGW456L13_2886 at 3215.502 kb on - strand, within PfGW456L13_2886 at 3215.502 kb on - strand, within PfGW456L13_2886 at 3215.502 kb on - strand, within PfGW456L13_2886 at 3215.504 kb on + strand, within PfGW456L13_2886 at 3215.504 kb on + strand, within PfGW456L13_2886 at 3215.505 kb on - strand, within PfGW456L13_2886 at 3215.505 kb on - strand, within PfGW456L13_2886 at 3215.535 kb on - strand, within PfGW456L13_2886 at 3215.586 kb on + strand, within PfGW456L13_2886 at 3215.588 kb on + strand, within PfGW456L13_2886 at 3215.589 kb on - strand, within PfGW456L13_2886 at 3215.731 kb on - strand, within PfGW456L13_2886 at 3215.925 kb on + strand, within PfGW456L13_2886 at 3215.933 kb on + strand, within PfGW456L13_2886 at 3215.933 kb on + strand, within PfGW456L13_2886 at 3215.933 kb on + strand, within PfGW456L13_2886 at 3215.934 kb on - strand, within PfGW456L13_2886
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.5 mg/ml remove 3,213,498 - -0.8 3,213,517 - +1.0 3,213,534 - +1.1 3,213,610 + +1.1 3,213,611 - -1.3 3,213,611 - -1.6 3,213,656 + +1.1 3,213,657 - +0.0 3,213,657 - -0.2 3,213,657 - +0.2 3,213,659 + +0.1 3,213,659 + +0.4 3,213,660 - -1.6 3,213,660 - +0.7 3,213,716 + -0.1 3,213,761 + +1.4 3,213,762 - +0.2 3,213,877 + PfGW456L13_2884 0.14 -1.0 3,213,894 - PfGW456L13_2884 0.17 -0.6 3,213,896 + PfGW456L13_2884 0.18 -0.4 3,213,896 + PfGW456L13_2884 0.18 +0.5 3,213,897 - PfGW456L13_2884 0.18 +1.7 3,213,897 - PfGW456L13_2884 0.18 -0.3 3,213,897 - PfGW456L13_2884 0.18 +0.2 3,213,996 - PfGW456L13_2884 0.39 -1.1 3,213,996 - PfGW456L13_2884 0.39 +0.7 3,214,028 + PfGW456L13_2884 0.45 -0.6 3,214,028 + +0.1 3,214,028 + PfGW456L13_2884 0.45 -0.5 3,214,028 + PfGW456L13_2884 0.45 +0.5 3,214,028 + PfGW456L13_2884 0.45 +0.4 3,214,028 + PfGW456L13_2884 0.45 -0.2 3,214,028 + PfGW456L13_2884 0.45 +0.0 3,214,028 + PfGW456L13_2884 0.45 +0.3 3,214,028 + PfGW456L13_2884 0.45 -0.1 3,214,028 + PfGW456L13_2884 0.45 -0.4 3,214,028 + PfGW456L13_2884 0.45 -2.1 3,214,028 + PfGW456L13_2884 0.45 -0.3 3,214,028 + PfGW456L13_2884 0.45 +1.5 3,214,029 - PfGW456L13_2884 0.45 +1.7 3,214,029 - PfGW456L13_2884 0.45 -0.3 3,214,029 - PfGW456L13_2884 0.45 +0.4 3,214,029 - PfGW456L13_2884 0.45 +0.7 3,214,029 - PfGW456L13_2884 0.45 +0.0 3,214,029 - PfGW456L13_2884 0.45 +1.5 3,214,029 - PfGW456L13_2884 0.45 +0.7 3,214,029 - PfGW456L13_2884 0.45 -2.0 3,214,029 - PfGW456L13_2884 0.45 +0.7 3,214,029 - PfGW456L13_2884 0.45 +0.6 3,214,029 - PfGW456L13_2884 0.45 -0.3 3,214,029 - PfGW456L13_2884 0.45 -2.3 3,214,029 - PfGW456L13_2884 0.45 +1.2 3,214,029 - PfGW456L13_2884 0.45 +0.3 3,214,029 - PfGW456L13_2884 0.45 -0.7 3,214,029 - PfGW456L13_2884 0.45 -0.3 3,214,176 - PfGW456L13_2884 0.76 +0.6 3,214,300 + -0.9 3,214,300 + -1.6 3,214,391 + -0.7 3,214,392 - -2.3 3,214,392 - -1.6 3,214,399 + -1.1 3,214,399 + -2.0 3,214,399 + -2.0 3,214,399 + -1.3 3,214,399 + -1.3 3,214,399 + -1.2 3,214,399 + -1.9 3,214,399 + +0.7 3,214,400 - -1.0 3,214,400 - -0.2 3,214,400 - -1.5 3,214,400 - -1.3 3,214,400 - -1.6 3,214,400 - -1.6 3,214,400 - -1.6 3,214,402 + -0.7 3,214,402 + -1.0 3,214,403 - -1.3 3,214,428 - -0.3 3,214,428 - -1.9 3,214,436 + -1.6 3,214,437 - -2.1 3,214,437 - -3.1 3,214,471 + -0.3 3,214,471 + -2.0 3,214,591 + PfGW456L13_2885 0.25 +1.7 3,214,686 + PfGW456L13_2885 0.42 -1.5 3,214,738 + PfGW456L13_2885 0.50 -1.3 3,214,738 + PfGW456L13_2885 0.50 -1.6 3,214,738 + PfGW456L13_2885 0.50 -1.1 3,214,739 - PfGW456L13_2885 0.51 -3.2 3,214,739 - PfGW456L13_2885 0.51 -1.6 3,214,739 - PfGW456L13_2885 0.51 -1.6 3,214,755 + PfGW456L13_2885 0.53 -1.6 3,214,755 + PfGW456L13_2885 0.53 -2.1 3,214,755 + PfGW456L13_2885 0.53 -2.8 3,214,755 + PfGW456L13_2885 0.53 -1.1 3,214,755 + PfGW456L13_2885 0.53 -1.9 3,214,756 - PfGW456L13_2885 0.54 -1.9 3,214,756 - PfGW456L13_2885 0.54 -1.9 3,214,756 - PfGW456L13_2885 0.54 -0.6 3,214,756 - PfGW456L13_2885 0.54 -1.9 3,214,756 - PfGW456L13_2885 0.54 -2.3 3,214,882 + PfGW456L13_2885 0.75 -1.0 3,214,882 + PfGW456L13_2885 0.75 -1.3 3,214,882 + PfGW456L13_2885 0.75 -1.3 3,214,882 + PfGW456L13_2885 0.75 -1.6 3,214,883 - PfGW456L13_2885 0.75 -1.3 3,214,883 - PfGW456L13_2885 0.75 -3.2 3,214,933 - PfGW456L13_2885 0.84 -1.5 3,214,933 - PfGW456L13_2885 0.84 -0.9 3,215,123 + -0.4 3,215,124 - +0.7 3,215,166 - +0.5 3,215,303 + PfGW456L13_2886 0.15 -0.2 3,215,303 + PfGW456L13_2886 0.15 -0.3 3,215,303 + PfGW456L13_2886 0.15 +0.5 3,215,304 - PfGW456L13_2886 0.15 +0.0 3,215,306 - PfGW456L13_2886 0.15 -0.4 3,215,306 - PfGW456L13_2886 0.15 -0.3 3,215,306 - PfGW456L13_2886 0.15 +0.3 3,215,306 - PfGW456L13_2886 0.15 -0.4 3,215,327 - PfGW456L13_2886 0.16 -0.7 3,215,327 - PfGW456L13_2886 0.16 -2.3 3,215,339 + +0.7 3,215,339 + PfGW456L13_2886 0.17 -0.8 3,215,340 - PfGW456L13_2886 0.17 -2.1 3,215,340 - PfGW456L13_2886 0.17 +0.1 3,215,340 - PfGW456L13_2886 0.17 -0.5 3,215,411 + PfGW456L13_2886 0.21 +0.0 3,215,411 + PfGW456L13_2886 0.21 -0.9 3,215,412 - PfGW456L13_2886 0.21 -1.3 3,215,501 + PfGW456L13_2886 0.26 -1.0 3,215,501 + PfGW456L13_2886 0.26 -0.6 3,215,501 + PfGW456L13_2886 0.26 -1.6 3,215,501 + PfGW456L13_2886 0.26 -0.3 3,215,501 + PfGW456L13_2886 0.26 -2.3 3,215,501 + PfGW456L13_2886 0.26 +0.4 3,215,502 - PfGW456L13_2886 0.26 -2.6 3,215,502 - PfGW456L13_2886 0.26 +0.4 3,215,502 - PfGW456L13_2886 0.26 -1.3 3,215,502 - PfGW456L13_2886 0.26 +0.2 3,215,504 + PfGW456L13_2886 0.26 +0.1 3,215,504 + PfGW456L13_2886 0.26 -1.5 3,215,505 - PfGW456L13_2886 0.26 +0.2 3,215,505 - PfGW456L13_2886 0.26 -0.4 3,215,535 - PfGW456L13_2886 0.28 -2.1 3,215,586 + PfGW456L13_2886 0.30 -0.4 3,215,588 + PfGW456L13_2886 0.31 +0.4 3,215,589 - PfGW456L13_2886 0.31 -0.1 3,215,731 - PfGW456L13_2886 0.38 -0.6 3,215,925 + PfGW456L13_2886 0.49 +0.2 3,215,933 + PfGW456L13_2886 0.50 +0.5 3,215,933 + PfGW456L13_2886 0.50 -0.2 3,215,933 + PfGW456L13_2886 0.50 -2.9 3,215,934 - PfGW456L13_2886 0.50 -1.4
Or see this region's nucleotide sequence