Experiment: Vancomycin 0.5 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_2190 and PfGW456L13_2191 are separated by 83 nucleotides PfGW456L13_2191 and PfGW456L13_2192 are separated by 512 nucleotides
PfGW456L13_2190 - Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-), at 2,403,159 to 2,404,190
_2190
PfGW456L13_2191 - nucleotide sugar epimerase/dehydratase WbpM, at 2,404,274 to 2,406,268
_2191
PfGW456L13_2192 - regulator of length of O-antigen component of lipopolysaccharide chains, at 2,406,781 to 2,408,061
_2192
Position (kb)
2404
2405
2406
2407 Strain fitness (log2 ratio)
-2
-1
0
1
2
3
4 at 2403.334 kb on + strand, within PfGW456L13_2190 at 2403.407 kb on - strand, within PfGW456L13_2190 at 2403.409 kb on + strand, within PfGW456L13_2190 at 2403.409 kb on + strand, within PfGW456L13_2190 at 2403.410 kb on - strand, within PfGW456L13_2190 at 2403.410 kb on - strand, within PfGW456L13_2190 at 2403.410 kb on - strand, within PfGW456L13_2190 at 2403.426 kb on - strand, within PfGW456L13_2190 at 2403.444 kb on - strand, within PfGW456L13_2190 at 2403.514 kb on + strand, within PfGW456L13_2190 at 2403.834 kb on - strand, within PfGW456L13_2190 at 2403.862 kb on + strand, within PfGW456L13_2190 at 2403.997 kb on - strand, within PfGW456L13_2190 at 2404.038 kb on - strand, within PfGW456L13_2190 at 2404.099 kb on + strand at 2404.100 kb on - strand at 2404.229 kb on + strand at 2404.229 kb on + strand at 2404.229 kb on + strand at 2404.229 kb on + strand at 2404.229 kb on + strand at 2404.262 kb on + strand at 2404.262 kb on + strand at 2404.262 kb on + strand at 2404.262 kb on + strand at 2404.262 kb on + strand at 2404.263 kb on - strand at 2404.356 kb on + strand at 2404.490 kb on + strand, within PfGW456L13_2191 at 2404.490 kb on + strand, within PfGW456L13_2191 at 2404.490 kb on + strand, within PfGW456L13_2191 at 2404.528 kb on + strand, within PfGW456L13_2191 at 2404.528 kb on + strand, within PfGW456L13_2191 at 2404.529 kb on - strand, within PfGW456L13_2191 at 2404.530 kb on + strand, within PfGW456L13_2191 at 2404.530 kb on + strand, within PfGW456L13_2191 at 2404.530 kb on + strand, within PfGW456L13_2191 at 2404.564 kb on - strand, within PfGW456L13_2191 at 2404.575 kb on + strand, within PfGW456L13_2191 at 2404.575 kb on + strand, within PfGW456L13_2191 at 2404.575 kb on + strand, within PfGW456L13_2191 at 2404.655 kb on - strand, within PfGW456L13_2191 at 2404.689 kb on - strand, within PfGW456L13_2191 at 2404.725 kb on + strand, within PfGW456L13_2191 at 2404.725 kb on + strand, within PfGW456L13_2191 at 2404.725 kb on + strand, within PfGW456L13_2191 at 2404.725 kb on + strand, within PfGW456L13_2191 at 2404.725 kb on + strand, within PfGW456L13_2191 at 2404.732 kb on + strand, within PfGW456L13_2191 at 2404.733 kb on - strand, within PfGW456L13_2191 at 2404.738 kb on + strand, within PfGW456L13_2191 at 2404.843 kb on + strand, within PfGW456L13_2191 at 2404.845 kb on + strand, within PfGW456L13_2191 at 2404.845 kb on + strand, within PfGW456L13_2191 at 2404.846 kb on - strand, within PfGW456L13_2191 at 2404.855 kb on + strand, within PfGW456L13_2191 at 2404.855 kb on + strand, within PfGW456L13_2191 at 2404.855 kb on + strand, within PfGW456L13_2191 at 2404.856 kb on - strand, within PfGW456L13_2191 at 2404.895 kb on + strand, within PfGW456L13_2191 at 2404.895 kb on + strand, within PfGW456L13_2191 at 2404.896 kb on - strand, within PfGW456L13_2191 at 2404.897 kb on + strand, within PfGW456L13_2191 at 2404.898 kb on - strand, within PfGW456L13_2191 at 2404.909 kb on + strand, within PfGW456L13_2191 at 2404.910 kb on - strand, within PfGW456L13_2191 at 2405.092 kb on - strand, within PfGW456L13_2191 at 2405.211 kb on + strand, within PfGW456L13_2191 at 2405.211 kb on + strand, within PfGW456L13_2191 at 2405.403 kb on + strand, within PfGW456L13_2191 at 2405.429 kb on + strand, within PfGW456L13_2191 at 2405.580 kb on + strand, within PfGW456L13_2191 at 2405.616 kb on + strand, within PfGW456L13_2191 at 2405.616 kb on + strand, within PfGW456L13_2191 at 2405.748 kb on + strand, within PfGW456L13_2191 at 2405.810 kb on + strand, within PfGW456L13_2191 at 2405.844 kb on + strand, within PfGW456L13_2191 at 2405.844 kb on + strand, within PfGW456L13_2191 at 2405.844 kb on + strand, within PfGW456L13_2191 at 2405.844 kb on + strand, within PfGW456L13_2191 at 2405.844 kb on + strand, within PfGW456L13_2191 at 2405.886 kb on + strand, within PfGW456L13_2191 at 2405.886 kb on + strand, within PfGW456L13_2191 at 2405.889 kb on + strand, within PfGW456L13_2191 at 2405.889 kb on + strand, within PfGW456L13_2191 at 2405.890 kb on - strand, within PfGW456L13_2191 at 2405.890 kb on - strand, within PfGW456L13_2191 at 2405.986 kb on + strand, within PfGW456L13_2191 at 2405.986 kb on + strand, within PfGW456L13_2191 at 2405.986 kb on + strand, within PfGW456L13_2191 at 2406.029 kb on + strand, within PfGW456L13_2191 at 2406.141 kb on + strand at 2406.141 kb on + strand at 2406.167 kb on + strand at 2406.167 kb on + strand at 2406.167 kb on + strand at 2406.209 kb on + strand at 2406.243 kb on - strand at 2406.289 kb on + strand at 2406.289 kb on + strand at 2406.290 kb on - strand at 2406.290 kb on - strand at 2406.311 kb on - strand at 2406.311 kb on - strand at 2406.387 kb on - strand at 2406.399 kb on + strand at 2406.399 kb on + strand at 2406.399 kb on + strand at 2406.400 kb on - strand at 2406.400 kb on - strand at 2406.400 kb on - strand at 2406.400 kb on - strand at 2406.443 kb on + strand at 2406.443 kb on + strand at 2406.443 kb on + strand at 2406.444 kb on - strand at 2406.444 kb on - strand at 2406.461 kb on + strand at 2406.461 kb on + strand at 2406.500 kb on + strand at 2406.513 kb on + strand at 2406.513 kb on + strand at 2406.514 kb on - strand at 2406.514 kb on - strand at 2406.516 kb on - strand at 2406.562 kb on + strand at 2406.562 kb on + strand at 2406.683 kb on + strand at 2406.753 kb on - strand at 2406.768 kb on - strand at 2406.768 kb on - strand at 2406.856 kb on + strand at 2406.857 kb on - strand at 2406.866 kb on - strand at 2406.931 kb on - strand, within PfGW456L13_2192 at 2406.943 kb on - strand, within PfGW456L13_2192 at 2407.032 kb on + strand, within PfGW456L13_2192 at 2407.033 kb on - strand, within PfGW456L13_2192 at 2407.181 kb on + strand, within PfGW456L13_2192 at 2407.189 kb on + strand, within PfGW456L13_2192 at 2407.190 kb on - strand, within PfGW456L13_2192 at 2407.190 kb on - strand, within PfGW456L13_2192 at 2407.205 kb on - strand, within PfGW456L13_2192
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.5 mg/ml remove 2,403,334 + PfGW456L13_2190 0.17 -0.8 2,403,407 - PfGW456L13_2190 0.24 +2.1 2,403,409 + PfGW456L13_2190 0.24 -1.2 2,403,409 + PfGW456L13_2190 0.24 +0.8 2,403,410 - PfGW456L13_2190 0.24 +1.0 2,403,410 - PfGW456L13_2190 0.24 +0.8 2,403,410 - PfGW456L13_2190 0.24 +1.2 2,403,426 - PfGW456L13_2190 0.26 +2.7 2,403,444 - PfGW456L13_2190 0.28 +1.8 2,403,514 + PfGW456L13_2190 0.34 -2.4 2,403,834 - PfGW456L13_2190 0.65 +3.3 2,403,862 + PfGW456L13_2190 0.68 +0.2 2,403,997 - PfGW456L13_2190 0.81 +1.2 2,404,038 - PfGW456L13_2190 0.85 +2.7 2,404,099 + +1.3 2,404,100 - -0.4 2,404,229 + +2.1 2,404,229 + -0.0 2,404,229 + +1.5 2,404,229 + +0.4 2,404,229 + +0.9 2,404,262 + +2.7 2,404,262 + +1.5 2,404,262 + +2.1 2,404,262 + +1.9 2,404,262 + +1.5 2,404,263 - +2.7 2,404,356 + +2.4 2,404,490 + PfGW456L13_2191 0.11 +1.6 2,404,490 + PfGW456L13_2191 0.11 +2.6 2,404,490 + PfGW456L13_2191 0.11 +3.0 2,404,528 + PfGW456L13_2191 0.13 +1.8 2,404,528 + PfGW456L13_2191 0.13 +3.5 2,404,529 - PfGW456L13_2191 0.13 +1.7 2,404,530 + PfGW456L13_2191 0.13 +1.1 2,404,530 + PfGW456L13_2191 0.13 +2.1 2,404,530 + PfGW456L13_2191 0.13 +2.0 2,404,564 - PfGW456L13_2191 0.15 +1.8 2,404,575 + PfGW456L13_2191 0.15 +2.4 2,404,575 + PfGW456L13_2191 0.15 +0.8 2,404,575 + PfGW456L13_2191 0.15 +2.4 2,404,655 - PfGW456L13_2191 0.19 +2.6 2,404,689 - PfGW456L13_2191 0.21 +1.3 2,404,725 + PfGW456L13_2191 0.23 +1.8 2,404,725 + PfGW456L13_2191 0.23 +2.6 2,404,725 + PfGW456L13_2191 0.23 +2.7 2,404,725 + PfGW456L13_2191 0.23 +3.6 2,404,725 + PfGW456L13_2191 0.23 +3.1 2,404,732 + PfGW456L13_2191 0.23 +1.8 2,404,733 - PfGW456L13_2191 0.23 -0.8 2,404,738 + PfGW456L13_2191 0.23 +1.7 2,404,843 + PfGW456L13_2191 0.29 +2.4 2,404,845 + PfGW456L13_2191 0.29 +2.9 2,404,845 + PfGW456L13_2191 0.29 +2.5 2,404,846 - PfGW456L13_2191 0.29 +1.8 2,404,855 + PfGW456L13_2191 0.29 +1.5 2,404,855 + PfGW456L13_2191 0.29 +2.8 2,404,855 + PfGW456L13_2191 0.29 +2.7 2,404,856 - PfGW456L13_2191 0.29 +0.5 2,404,895 + PfGW456L13_2191 0.31 +2.0 2,404,895 + PfGW456L13_2191 0.31 +0.6 2,404,896 - PfGW456L13_2191 0.31 +2.4 2,404,897 + PfGW456L13_2191 0.31 +2.5 2,404,898 - PfGW456L13_2191 0.31 +1.4 2,404,909 + PfGW456L13_2191 0.32 +2.1 2,404,910 - PfGW456L13_2191 0.32 +1.7 2,405,092 - PfGW456L13_2191 0.41 +0.5 2,405,211 + PfGW456L13_2191 0.47 +1.8 2,405,211 + PfGW456L13_2191 0.47 +2.5 2,405,403 + PfGW456L13_2191 0.57 +3.0 2,405,429 + PfGW456L13_2191 0.58 +3.0 2,405,580 + PfGW456L13_2191 0.65 +1.7 2,405,616 + PfGW456L13_2191 0.67 +3.4 2,405,616 + PfGW456L13_2191 0.67 +1.5 2,405,748 + PfGW456L13_2191 0.74 +1.9 2,405,810 + PfGW456L13_2191 0.77 +2.3 2,405,844 + PfGW456L13_2191 0.79 +4.4 2,405,844 + PfGW456L13_2191 0.79 +1.9 2,405,844 + PfGW456L13_2191 0.79 +3.1 2,405,844 + PfGW456L13_2191 0.79 +3.6 2,405,844 + PfGW456L13_2191 0.79 +2.3 2,405,886 + PfGW456L13_2191 0.81 +1.6 2,405,886 + PfGW456L13_2191 0.81 +1.3 2,405,889 + PfGW456L13_2191 0.81 +2.7 2,405,889 + PfGW456L13_2191 0.81 +2.6 2,405,890 - PfGW456L13_2191 0.81 +1.8 2,405,890 - PfGW456L13_2191 0.81 -0.8 2,405,986 + PfGW456L13_2191 0.86 +0.8 2,405,986 + PfGW456L13_2191 0.86 +2.7 2,405,986 + PfGW456L13_2191 0.86 +2.0 2,406,029 + PfGW456L13_2191 0.88 +2.6 2,406,141 + +3.1 2,406,141 + +2.1 2,406,167 + +3.4 2,406,167 + +2.7 2,406,167 + +2.7 2,406,209 + +1.7 2,406,243 - +1.3 2,406,289 + -0.7 2,406,289 + +0.8 2,406,290 - +0.9 2,406,290 - +0.4 2,406,311 - +0.2 2,406,311 - +1.0 2,406,387 - +1.4 2,406,399 + -0.3 2,406,399 + +1.2 2,406,399 + +0.7 2,406,400 - +0.0 2,406,400 - -0.2 2,406,400 - +0.8 2,406,400 - -1.8 2,406,443 + -0.1 2,406,443 + +0.7 2,406,443 + -0.0 2,406,444 - +0.4 2,406,444 - +1.0 2,406,461 + +0.5 2,406,461 + +0.2 2,406,500 + -1.0 2,406,513 + +0.4 2,406,513 + +2.6 2,406,514 - +0.8 2,406,514 - +2.0 2,406,516 - +0.9 2,406,562 + -0.0 2,406,562 + +1.6 2,406,683 + -1.7 2,406,753 - -0.9 2,406,768 - +0.1 2,406,768 - -0.3 2,406,856 + -2.2 2,406,857 - +0.1 2,406,866 - -0.3 2,406,931 - PfGW456L13_2192 0.12 +0.8 2,406,943 - PfGW456L13_2192 0.13 -0.5 2,407,032 + PfGW456L13_2192 0.20 -1.8 2,407,033 - PfGW456L13_2192 0.20 -0.5 2,407,181 + PfGW456L13_2192 0.31 -0.2 2,407,189 + PfGW456L13_2192 0.32 -1.8 2,407,190 - PfGW456L13_2192 0.32 -1.3 2,407,190 - PfGW456L13_2192 0.32 -0.4 2,407,205 - PfGW456L13_2192 0.33 +0.3
Or see this region's nucleotide sequence