Experiment: Vancomycin 0.5 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_2097 and PfGW456L13_2098 overlap by 14 nucleotides PfGW456L13_2098 and PfGW456L13_2099 are separated by 24 nucleotides PfGW456L13_2099 and PfGW456L13_2100 are separated by 54 nucleotides PfGW456L13_2100 and PfGW456L13_2101 are separated by 105 nucleotides
PfGW456L13_2097 - Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70), at 2,304,491 to 2,305,453
_2097
PfGW456L13_2098 - Similar to phosphoglycolate phosphatase, clustered with ribosomal large subunit pseudouridine synthase C, at 2,305,440 to 2,306,102
_2098
PfGW456L13_2099 - Periplasmic serine proteases (ClpP class), at 2,306,127 to 2,307,116
_2099
PfGW456L13_2100 - FIG146278: Maf/YceF/YhdE family protein, at 2,307,171 to 2,307,749
_2100
PfGW456L13_2101 - COG1399 protein, clustered with ribosomal protein L32p, at 2,307,855 to 2,308,382
_2101
Position (kb)
2306
2307
2308 Strain fitness (log2 ratio)
-2
-1
0
1
2
3 at 2305.244 kb on - strand, within PfGW456L13_2097 at 2305.283 kb on + strand, within PfGW456L13_2097 at 2305.283 kb on + strand, within PfGW456L13_2097 at 2305.284 kb on - strand, within PfGW456L13_2097 at 2305.349 kb on + strand, within PfGW456L13_2097 at 2305.349 kb on + strand, within PfGW456L13_2097 at 2305.350 kb on - strand, within PfGW456L13_2097 at 2305.350 kb on - strand, within PfGW456L13_2097 at 2305.350 kb on - strand, within PfGW456L13_2097 at 2305.350 kb on - strand, within PfGW456L13_2097 at 2305.350 kb on - strand, within PfGW456L13_2097 at 2305.350 kb on - strand, within PfGW456L13_2097 at 2305.350 kb on - strand, within PfGW456L13_2097 at 2305.350 kb on - strand, within PfGW456L13_2097 at 2305.350 kb on - strand, within PfGW456L13_2097 at 2305.350 kb on - strand, within PfGW456L13_2097 at 2305.350 kb on - strand, within PfGW456L13_2097 at 2305.455 kb on + strand at 2305.455 kb on + strand at 2305.456 kb on - strand at 2305.665 kb on + strand, within PfGW456L13_2098 at 2305.665 kb on + strand, within PfGW456L13_2098 at 2305.666 kb on - strand, within PfGW456L13_2098 at 2305.666 kb on - strand, within PfGW456L13_2098 at 2305.677 kb on + strand, within PfGW456L13_2098 at 2305.677 kb on + strand, within PfGW456L13_2098 at 2305.677 kb on + strand, within PfGW456L13_2098 at 2305.677 kb on + strand, within PfGW456L13_2098 at 2305.677 kb on + strand, within PfGW456L13_2098 at 2305.677 kb on + strand, within PfGW456L13_2098 at 2305.677 kb on + strand, within PfGW456L13_2098 at 2305.677 kb on + strand, within PfGW456L13_2098 at 2305.677 kb on + strand, within PfGW456L13_2098 at 2305.677 kb on + strand, within PfGW456L13_2098 at 2305.677 kb on + strand, within PfGW456L13_2098 at 2305.677 kb on + strand, within PfGW456L13_2098 at 2305.678 kb on - strand, within PfGW456L13_2098 at 2305.678 kb on - strand, within PfGW456L13_2098 at 2305.678 kb on - strand, within PfGW456L13_2098 at 2305.678 kb on - strand, within PfGW456L13_2098 at 2305.678 kb on - strand, within PfGW456L13_2098 at 2305.678 kb on - strand, within PfGW456L13_2098 at 2305.678 kb on - strand, within PfGW456L13_2098 at 2305.678 kb on - strand, within PfGW456L13_2098 at 2305.678 kb on - strand, within PfGW456L13_2098 at 2305.678 kb on - strand, within PfGW456L13_2098 at 2305.678 kb on - strand, within PfGW456L13_2098 at 2305.678 kb on - strand, within PfGW456L13_2098 at 2305.755 kb on + strand, within PfGW456L13_2098 at 2305.755 kb on + strand, within PfGW456L13_2098 at 2305.830 kb on + strand, within PfGW456L13_2098 at 2305.830 kb on + strand, within PfGW456L13_2098 at 2305.831 kb on - strand, within PfGW456L13_2098 at 2306.004 kb on + strand, within PfGW456L13_2098 at 2306.004 kb on + strand, within PfGW456L13_2098 at 2306.005 kb on - strand, within PfGW456L13_2098 at 2306.005 kb on - strand, within PfGW456L13_2098 at 2306.005 kb on - strand, within PfGW456L13_2098 at 2306.037 kb on + strand at 2306.037 kb on + strand at 2306.037 kb on + strand at 2306.037 kb on + strand at 2306.038 kb on - strand at 2306.038 kb on - strand at 2306.221 kb on + strand at 2306.221 kb on + strand at 2306.222 kb on - strand at 2306.222 kb on - strand at 2306.222 kb on - strand at 2306.254 kb on + strand, within PfGW456L13_2099 at 2306.254 kb on + strand, within PfGW456L13_2099 at 2306.280 kb on + strand, within PfGW456L13_2099 at 2306.281 kb on - strand, within PfGW456L13_2099 at 2306.281 kb on - strand, within PfGW456L13_2099 at 2306.281 kb on - strand, within PfGW456L13_2099 at 2306.352 kb on + strand, within PfGW456L13_2099 at 2306.352 kb on + strand, within PfGW456L13_2099 at 2306.353 kb on - strand, within PfGW456L13_2099 at 2306.353 kb on - strand, within PfGW456L13_2099 at 2306.353 kb on - strand, within PfGW456L13_2099 at 2306.353 kb on - strand, within PfGW456L13_2099 at 2306.353 kb on - strand, within PfGW456L13_2099 at 2306.353 kb on - strand, within PfGW456L13_2099 at 2306.353 kb on - strand, within PfGW456L13_2099 at 2306.353 kb on - strand, within PfGW456L13_2099 at 2306.353 kb on - strand, within PfGW456L13_2099 at 2306.414 kb on + strand, within PfGW456L13_2099 at 2306.415 kb on - strand, within PfGW456L13_2099 at 2306.511 kb on + strand, within PfGW456L13_2099 at 2306.517 kb on + strand, within PfGW456L13_2099 at 2306.517 kb on + strand, within PfGW456L13_2099 at 2306.517 kb on + strand, within PfGW456L13_2099 at 2306.517 kb on + strand, within PfGW456L13_2099 at 2306.517 kb on + strand, within PfGW456L13_2099 at 2306.518 kb on - strand, within PfGW456L13_2099 at 2306.565 kb on + strand, within PfGW456L13_2099 at 2306.565 kb on + strand, within PfGW456L13_2099 at 2306.566 kb on - strand, within PfGW456L13_2099 at 2306.566 kb on - strand, within PfGW456L13_2099 at 2306.566 kb on - strand, within PfGW456L13_2099 at 2306.601 kb on + strand, within PfGW456L13_2099 at 2306.601 kb on + strand, within PfGW456L13_2099 at 2306.601 kb on + strand, within PfGW456L13_2099 at 2306.602 kb on - strand, within PfGW456L13_2099 at 2306.604 kb on + strand, within PfGW456L13_2099 at 2306.604 kb on + strand, within PfGW456L13_2099 at 2306.604 kb on + strand, within PfGW456L13_2099 at 2306.604 kb on + strand, within PfGW456L13_2099 at 2306.604 kb on + strand, within PfGW456L13_2099 at 2306.604 kb on + strand, within PfGW456L13_2099 at 2306.604 kb on + strand, within PfGW456L13_2099 at 2306.604 kb on + strand, within PfGW456L13_2099 at 2306.605 kb on - strand, within PfGW456L13_2099 at 2306.605 kb on - strand, within PfGW456L13_2099 at 2306.605 kb on - strand, within PfGW456L13_2099 at 2306.631 kb on + strand, within PfGW456L13_2099 at 2306.726 kb on + strand at 2306.726 kb on + strand, within PfGW456L13_2099 at 2306.730 kb on + strand, within PfGW456L13_2099 at 2306.730 kb on + strand, within PfGW456L13_2099 at 2306.730 kb on + strand, within PfGW456L13_2099 at 2306.730 kb on + strand, within PfGW456L13_2099 at 2306.730 kb on + strand, within PfGW456L13_2099 at 2306.730 kb on + strand, within PfGW456L13_2099 at 2306.730 kb on + strand, within PfGW456L13_2099 at 2306.730 kb on + strand, within PfGW456L13_2099 at 2306.731 kb on - strand, within PfGW456L13_2099 at 2306.731 kb on - strand, within PfGW456L13_2099 at 2306.731 kb on - strand, within PfGW456L13_2099 at 2306.731 kb on - strand, within PfGW456L13_2099 at 2306.731 kb on - strand, within PfGW456L13_2099 at 2306.731 kb on - strand, within PfGW456L13_2099 at 2306.731 kb on - strand, within PfGW456L13_2099 at 2306.731 kb on - strand, within PfGW456L13_2099 at 2306.731 kb on - strand, within PfGW456L13_2099 at 2306.731 kb on - strand, within PfGW456L13_2099 at 2306.731 kb on - strand, within PfGW456L13_2099 at 2306.731 kb on - strand, within PfGW456L13_2099 at 2306.840 kb on + strand, within PfGW456L13_2099 at 2306.841 kb on - strand, within PfGW456L13_2099 at 2306.841 kb on - strand, within PfGW456L13_2099 at 2307.095 kb on + strand at 2307.163 kb on - strand at 2307.317 kb on - strand, within PfGW456L13_2100 at 2307.337 kb on + strand, within PfGW456L13_2100 at 2307.337 kb on + strand, within PfGW456L13_2100 at 2307.375 kb on + strand, within PfGW456L13_2100 at 2307.375 kb on + strand, within PfGW456L13_2100 at 2307.375 kb on + strand, within PfGW456L13_2100 at 2307.376 kb on - strand, within PfGW456L13_2100 at 2307.376 kb on - strand, within PfGW456L13_2100 at 2307.555 kb on + strand, within PfGW456L13_2100 at 2307.738 kb on + strand at 2307.738 kb on + strand at 2307.761 kb on + strand at 2307.779 kb on + strand at 2307.780 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.5 mg/ml remove 2,305,244 - PfGW456L13_2097 0.78 +0.3 2,305,283 + PfGW456L13_2097 0.82 +0.3 2,305,283 + PfGW456L13_2097 0.82 +0.4 2,305,284 - PfGW456L13_2097 0.82 -1.5 2,305,349 + PfGW456L13_2097 0.89 +0.2 2,305,349 + PfGW456L13_2097 0.89 -0.2 2,305,350 - PfGW456L13_2097 0.89 +0.7 2,305,350 - PfGW456L13_2097 0.89 -0.5 2,305,350 - PfGW456L13_2097 0.89 -0.1 2,305,350 - PfGW456L13_2097 0.89 -0.1 2,305,350 - PfGW456L13_2097 0.89 -1.2 2,305,350 - PfGW456L13_2097 0.89 -2.2 2,305,350 - PfGW456L13_2097 0.89 +0.4 2,305,350 - PfGW456L13_2097 0.89 -0.6 2,305,350 - PfGW456L13_2097 0.89 +1.1 2,305,350 - PfGW456L13_2097 0.89 +1.4 2,305,350 - PfGW456L13_2097 0.89 -1.0 2,305,455 + +0.8 2,305,455 + +1.2 2,305,456 - +0.0 2,305,665 + PfGW456L13_2098 0.34 +0.5 2,305,665 + PfGW456L13_2098 0.34 -0.2 2,305,666 - PfGW456L13_2098 0.34 -0.2 2,305,666 - PfGW456L13_2098 0.34 -0.2 2,305,677 + PfGW456L13_2098 0.36 -1.4 2,305,677 + PfGW456L13_2098 0.36 +0.5 2,305,677 + PfGW456L13_2098 0.36 -1.0 2,305,677 + PfGW456L13_2098 0.36 -2.0 2,305,677 + PfGW456L13_2098 0.36 -0.3 2,305,677 + PfGW456L13_2098 0.36 +2.8 2,305,677 + PfGW456L13_2098 0.36 -0.1 2,305,677 + PfGW456L13_2098 0.36 -1.6 2,305,677 + PfGW456L13_2098 0.36 -0.3 2,305,677 + PfGW456L13_2098 0.36 -0.2 2,305,677 + PfGW456L13_2098 0.36 +1.4 2,305,677 + PfGW456L13_2098 0.36 -1.4 2,305,678 - PfGW456L13_2098 0.36 +0.1 2,305,678 - PfGW456L13_2098 0.36 +0.1 2,305,678 - PfGW456L13_2098 0.36 +0.2 2,305,678 - PfGW456L13_2098 0.36 -0.8 2,305,678 - PfGW456L13_2098 0.36 -1.1 2,305,678 - PfGW456L13_2098 0.36 -0.2 2,305,678 - PfGW456L13_2098 0.36 -0.4 2,305,678 - PfGW456L13_2098 0.36 +0.8 2,305,678 - PfGW456L13_2098 0.36 -0.9 2,305,678 - PfGW456L13_2098 0.36 -2.0 2,305,678 - PfGW456L13_2098 0.36 -0.1 2,305,678 - PfGW456L13_2098 0.36 +0.1 2,305,755 + PfGW456L13_2098 0.48 +0.4 2,305,755 + PfGW456L13_2098 0.48 +0.8 2,305,830 + PfGW456L13_2098 0.59 -0.8 2,305,830 + PfGW456L13_2098 0.59 +0.3 2,305,831 - PfGW456L13_2098 0.59 -2.5 2,306,004 + PfGW456L13_2098 0.85 +0.5 2,306,004 + PfGW456L13_2098 0.85 +1.1 2,306,005 - PfGW456L13_2098 0.85 -2.0 2,306,005 - PfGW456L13_2098 0.85 -2.4 2,306,005 - PfGW456L13_2098 0.85 +2.0 2,306,037 + -0.1 2,306,037 + +0.1 2,306,037 + +0.4 2,306,037 + -0.9 2,306,038 - +0.3 2,306,038 - +1.2 2,306,221 + +1.0 2,306,221 + -0.4 2,306,222 - +0.1 2,306,222 - -0.2 2,306,222 - -0.6 2,306,254 + PfGW456L13_2099 0.13 +0.4 2,306,254 + PfGW456L13_2099 0.13 +0.2 2,306,280 + PfGW456L13_2099 0.15 +1.4 2,306,281 - PfGW456L13_2099 0.16 -0.5 2,306,281 - PfGW456L13_2099 0.16 +1.2 2,306,281 - PfGW456L13_2099 0.16 -0.6 2,306,352 + PfGW456L13_2099 0.23 +1.4 2,306,352 + PfGW456L13_2099 0.23 -0.9 2,306,353 - PfGW456L13_2099 0.23 +2.1 2,306,353 - PfGW456L13_2099 0.23 -1.3 2,306,353 - PfGW456L13_2099 0.23 -0.4 2,306,353 - PfGW456L13_2099 0.23 +0.6 2,306,353 - PfGW456L13_2099 0.23 -0.8 2,306,353 - PfGW456L13_2099 0.23 +0.5 2,306,353 - PfGW456L13_2099 0.23 +0.1 2,306,353 - PfGW456L13_2099 0.23 -0.6 2,306,353 - PfGW456L13_2099 0.23 +0.6 2,306,414 + PfGW456L13_2099 0.29 +0.2 2,306,415 - PfGW456L13_2099 0.29 -1.1 2,306,511 + PfGW456L13_2099 0.39 -1.1 2,306,517 + PfGW456L13_2099 0.39 -0.4 2,306,517 + PfGW456L13_2099 0.39 -0.2 2,306,517 + PfGW456L13_2099 0.39 -0.5 2,306,517 + PfGW456L13_2099 0.39 +0.3 2,306,517 + PfGW456L13_2099 0.39 -0.4 2,306,518 - PfGW456L13_2099 0.39 -1.5 2,306,565 + PfGW456L13_2099 0.44 -0.2 2,306,565 + PfGW456L13_2099 0.44 +0.8 2,306,566 - PfGW456L13_2099 0.44 +0.8 2,306,566 - PfGW456L13_2099 0.44 +0.4 2,306,566 - PfGW456L13_2099 0.44 -1.1 2,306,601 + PfGW456L13_2099 0.48 -0.5 2,306,601 + PfGW456L13_2099 0.48 -0.2 2,306,601 + PfGW456L13_2099 0.48 +1.2 2,306,602 - PfGW456L13_2099 0.48 -0.5 2,306,604 + PfGW456L13_2099 0.48 -0.1 2,306,604 + PfGW456L13_2099 0.48 +0.2 2,306,604 + PfGW456L13_2099 0.48 -1.0 2,306,604 + PfGW456L13_2099 0.48 -0.5 2,306,604 + PfGW456L13_2099 0.48 +0.5 2,306,604 + PfGW456L13_2099 0.48 -1.4 2,306,604 + PfGW456L13_2099 0.48 -2.3 2,306,604 + PfGW456L13_2099 0.48 -0.0 2,306,605 - PfGW456L13_2099 0.48 -0.1 2,306,605 - PfGW456L13_2099 0.48 -0.4 2,306,605 - PfGW456L13_2099 0.48 -2.7 2,306,631 + PfGW456L13_2099 0.51 -0.7 2,306,726 + +2.8 2,306,726 + PfGW456L13_2099 0.61 -0.9 2,306,730 + PfGW456L13_2099 0.61 +0.8 2,306,730 + PfGW456L13_2099 0.61 +0.5 2,306,730 + PfGW456L13_2099 0.61 +2.1 2,306,730 + PfGW456L13_2099 0.61 -0.3 2,306,730 + PfGW456L13_2099 0.61 -1.2 2,306,730 + PfGW456L13_2099 0.61 -0.2 2,306,730 + PfGW456L13_2099 0.61 +0.8 2,306,730 + PfGW456L13_2099 0.61 -0.7 2,306,731 - PfGW456L13_2099 0.61 +1.4 2,306,731 - PfGW456L13_2099 0.61 +0.5 2,306,731 - PfGW456L13_2099 0.61 -0.9 2,306,731 - PfGW456L13_2099 0.61 +0.8 2,306,731 - PfGW456L13_2099 0.61 -0.3 2,306,731 - PfGW456L13_2099 0.61 +0.8 2,306,731 - PfGW456L13_2099 0.61 -1.9 2,306,731 - PfGW456L13_2099 0.61 +0.1 2,306,731 - PfGW456L13_2099 0.61 +0.2 2,306,731 - PfGW456L13_2099 0.61 -0.1 2,306,731 - PfGW456L13_2099 0.61 +0.5 2,306,731 - PfGW456L13_2099 0.61 +0.4 2,306,840 + PfGW456L13_2099 0.72 -0.6 2,306,841 - PfGW456L13_2099 0.72 -1.1 2,306,841 - PfGW456L13_2099 0.72 -0.8 2,307,095 + +1.4 2,307,163 - +1.4 2,307,317 - PfGW456L13_2100 0.25 +0.0 2,307,337 + PfGW456L13_2100 0.29 +0.2 2,307,337 + PfGW456L13_2100 0.29 +1.1 2,307,375 + PfGW456L13_2100 0.35 +0.2 2,307,375 + PfGW456L13_2100 0.35 -1.1 2,307,375 + PfGW456L13_2100 0.35 +0.5 2,307,376 - PfGW456L13_2100 0.35 +1.5 2,307,376 - PfGW456L13_2100 0.35 +0.2 2,307,555 + PfGW456L13_2100 0.66 +0.3 2,307,738 + -0.1 2,307,738 + +1.0 2,307,761 + +0.1 2,307,779 + -1.1 2,307,780 - -1.5
Or see this region's nucleotide sequence