Experiment: Vancomycin 0.5 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_2088 and PfGW456L13_2089 overlap by 1 nucleotides PfGW456L13_2089 and PfGW456L13_2090 overlap by 4 nucleotides PfGW456L13_2090 and PfGW456L13_2091 are separated by 241 nucleotides PfGW456L13_2091 and PfGW456L13_2092 overlap by 4 nucleotides
PfGW456L13_2088 - 3-deoxy-manno-octulosonate cytidylyltransferase (EC 2.7.7.38), at 2,293,487 to 2,294,251
_2088
PfGW456L13_2089 - Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48), at 2,294,251 to 2,294,715
_2089
PfGW456L13_2090 - UDP-N-acetylenolpyruvoylglucosamine reductase (EC 1.1.1.158), at 2,294,712 to 2,295,731
_2090
PfGW456L13_2091 - Isoquinoline 1-oxidoreductase alpha subunit (EC 1.3.99.16), at 2,295,973 to 2,296,443
_2091
PfGW456L13_2092 - Isoquinoline 1-oxidoreductase beta subunit (EC 1.3.99.16), at 2,296,440 to 2,298,761
_2092
Position (kb)
2294
2295
2296 Strain fitness (log2 ratio)
-2
-1
0
1
2
3 at 2294.319 kb on + strand, within PfGW456L13_2089 at 2294.319 kb on + strand, within PfGW456L13_2089 at 2294.491 kb on + strand, within PfGW456L13_2089 at 2294.623 kb on + strand, within PfGW456L13_2089 at 2294.623 kb on + strand, within PfGW456L13_2089 at 2295.734 kb on + strand at 2295.734 kb on + strand at 2295.735 kb on - strand at 2295.735 kb on - strand at 2295.735 kb on - strand at 2295.735 kb on - strand at 2295.735 kb on - strand at 2295.773 kb on + strand at 2295.773 kb on + strand at 2295.774 kb on - strand at 2295.795 kb on - strand at 2295.795 kb on - strand at 2295.810 kb on + strand at 2295.810 kb on + strand at 2295.811 kb on - strand at 2295.811 kb on - strand at 2295.811 kb on - strand at 2295.862 kb on + strand at 2295.863 kb on - strand at 2295.863 kb on - strand at 2295.863 kb on - strand at 2295.874 kb on + strand at 2295.874 kb on + strand at 2295.874 kb on + strand at 2295.874 kb on + strand at 2295.874 kb on + strand at 2295.874 kb on + strand at 2295.874 kb on + strand at 2295.874 kb on + strand at 2295.875 kb on - strand at 2295.875 kb on - strand at 2295.875 kb on - strand at 2295.875 kb on - strand at 2295.875 kb on - strand at 2295.875 kb on - strand at 2295.875 kb on - strand at 2295.958 kb on + strand at 2295.958 kb on + strand at 2295.959 kb on - strand at 2296.063 kb on + strand, within PfGW456L13_2091 at 2296.110 kb on + strand, within PfGW456L13_2091 at 2296.111 kb on - strand, within PfGW456L13_2091 at 2296.111 kb on - strand, within PfGW456L13_2091 at 2296.149 kb on + strand, within PfGW456L13_2091 at 2296.149 kb on + strand, within PfGW456L13_2091 at 2296.149 kb on + strand, within PfGW456L13_2091 at 2296.149 kb on + strand, within PfGW456L13_2091 at 2296.149 kb on + strand, within PfGW456L13_2091 at 2296.150 kb on - strand, within PfGW456L13_2091 at 2296.150 kb on - strand, within PfGW456L13_2091 at 2296.381 kb on + strand, within PfGW456L13_2091 at 2296.381 kb on + strand, within PfGW456L13_2091 at 2296.381 kb on + strand, within PfGW456L13_2091 at 2296.381 kb on + strand, within PfGW456L13_2091 at 2296.381 kb on + strand, within PfGW456L13_2091 at 2296.381 kb on + strand, within PfGW456L13_2091 at 2296.381 kb on + strand, within PfGW456L13_2091 at 2296.381 kb on + strand, within PfGW456L13_2091 at 2296.381 kb on + strand, within PfGW456L13_2091 at 2296.381 kb on + strand, within PfGW456L13_2091 at 2296.381 kb on + strand, within PfGW456L13_2091 at 2296.382 kb on - strand, within PfGW456L13_2091 at 2296.382 kb on - strand, within PfGW456L13_2091 at 2296.382 kb on - strand, within PfGW456L13_2091 at 2296.382 kb on - strand, within PfGW456L13_2091 at 2296.382 kb on - strand, within PfGW456L13_2091 at 2296.382 kb on - strand, within PfGW456L13_2091 at 2296.382 kb on - strand, within PfGW456L13_2091 at 2296.382 kb on - strand, within PfGW456L13_2091 at 2296.382 kb on - strand, within PfGW456L13_2091 at 2296.382 kb on - strand, within PfGW456L13_2091 at 2296.382 kb on - strand, within PfGW456L13_2091 at 2296.382 kb on - strand, within PfGW456L13_2091 at 2296.382 kb on - strand, within PfGW456L13_2091 at 2296.382 kb on - strand, within PfGW456L13_2091 at 2296.382 kb on - strand, within PfGW456L13_2091 at 2296.384 kb on - strand, within PfGW456L13_2091 at 2296.389 kb on + strand, within PfGW456L13_2091 at 2296.390 kb on - strand, within PfGW456L13_2091 at 2296.629 kb on + strand at 2296.629 kb on + strand at 2296.629 kb on + strand at 2296.630 kb on - strand at 2296.630 kb on - strand at 2296.637 kb on + strand at 2296.665 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.5 mg/ml remove 2,294,319 + PfGW456L13_2089 0.15 +0.4 2,294,319 + PfGW456L13_2089 0.15 -0.4 2,294,491 + PfGW456L13_2089 0.52 -0.7 2,294,623 + PfGW456L13_2089 0.80 +0.9 2,294,623 + PfGW456L13_2089 0.80 +0.8 2,295,734 + +0.6 2,295,734 + +0.6 2,295,735 - +0.0 2,295,735 - +0.2 2,295,735 - -0.2 2,295,735 - -0.3 2,295,735 - +1.1 2,295,773 + +0.1 2,295,773 + +0.6 2,295,774 - -0.5 2,295,795 - -1.3 2,295,795 - -0.2 2,295,810 + +1.2 2,295,810 + -0.9 2,295,811 - +0.2 2,295,811 - -0.3 2,295,811 - -1.8 2,295,862 + -0.4 2,295,863 - +2.9 2,295,863 - -0.3 2,295,863 - -0.1 2,295,874 + +0.6 2,295,874 + +0.6 2,295,874 + -0.2 2,295,874 + +0.9 2,295,874 + +0.1 2,295,874 + -0.8 2,295,874 + +0.1 2,295,874 + +0.1 2,295,875 - +1.3 2,295,875 - +0.3 2,295,875 - -0.2 2,295,875 - +0.4 2,295,875 - -1.9 2,295,875 - -0.2 2,295,875 - +0.1 2,295,958 + +1.0 2,295,958 + -0.7 2,295,959 - +1.2 2,296,063 + PfGW456L13_2091 0.19 -0.2 2,296,110 + PfGW456L13_2091 0.29 -0.5 2,296,111 - PfGW456L13_2091 0.29 +0.1 2,296,111 - PfGW456L13_2091 0.29 +0.9 2,296,149 + PfGW456L13_2091 0.37 +0.1 2,296,149 + PfGW456L13_2091 0.37 -0.0 2,296,149 + PfGW456L13_2091 0.37 -0.0 2,296,149 + PfGW456L13_2091 0.37 +0.3 2,296,149 + PfGW456L13_2091 0.37 +0.2 2,296,150 - PfGW456L13_2091 0.38 +1.7 2,296,150 - PfGW456L13_2091 0.38 -0.2 2,296,381 + PfGW456L13_2091 0.87 -0.6 2,296,381 + PfGW456L13_2091 0.87 -0.3 2,296,381 + PfGW456L13_2091 0.87 -1.4 2,296,381 + PfGW456L13_2091 0.87 +0.5 2,296,381 + PfGW456L13_2091 0.87 +1.2 2,296,381 + PfGW456L13_2091 0.87 -0.9 2,296,381 + PfGW456L13_2091 0.87 -0.7 2,296,381 + PfGW456L13_2091 0.87 +0.6 2,296,381 + PfGW456L13_2091 0.87 +0.0 2,296,381 + PfGW456L13_2091 0.87 +0.2 2,296,381 + PfGW456L13_2091 0.87 -0.2 2,296,382 - PfGW456L13_2091 0.87 +0.5 2,296,382 - PfGW456L13_2091 0.87 -0.7 2,296,382 - PfGW456L13_2091 0.87 -0.5 2,296,382 - PfGW456L13_2091 0.87 +0.0 2,296,382 - PfGW456L13_2091 0.87 +1.5 2,296,382 - PfGW456L13_2091 0.87 -0.4 2,296,382 - PfGW456L13_2091 0.87 -0.9 2,296,382 - PfGW456L13_2091 0.87 -0.2 2,296,382 - PfGW456L13_2091 0.87 +1.1 2,296,382 - PfGW456L13_2091 0.87 -0.1 2,296,382 - PfGW456L13_2091 0.87 +0.3 2,296,382 - PfGW456L13_2091 0.87 -2.0 2,296,382 - PfGW456L13_2091 0.87 +0.8 2,296,382 - PfGW456L13_2091 0.87 +0.1 2,296,382 - PfGW456L13_2091 0.87 +1.5 2,296,384 - PfGW456L13_2091 0.87 -1.0 2,296,389 + PfGW456L13_2091 0.88 +0.2 2,296,390 - PfGW456L13_2091 0.89 -2.0 2,296,629 + +0.8 2,296,629 + +0.8 2,296,629 + +0.8 2,296,630 - +1.4 2,296,630 - -0.2 2,296,637 + +0.5 2,296,665 - +0.4
Or see this region's nucleotide sequence