Experiment: Vancomycin 0.5 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_1640 and PfGW456L13_1641 are separated by 103 nucleotides PfGW456L13_1641 and PfGW456L13_1642 overlap by 1 nucleotides PfGW456L13_1642 and PfGW456L13_1643 are separated by 210 nucleotides
PfGW456L13_1640 - Phosphoheptose isomerase (EC 5.3.1.-), at 1,800,919 to 1,801,512
_1640
PfGW456L13_1641 - Predicted endonuclease distantly related to archaeal Holliday junction resolvase, at 1,801,616 to 1,801,978
_1641
PfGW456L13_1642 - LppC putative lipoprotein, at 1,801,978 to 1,803,789
_1642
PfGW456L13_1643 - rRNA small subunit methyltransferase I, at 1,804,000 to 1,804,872
_1643
Position (kb)
1801
1802
1803
1804 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2
3 at 1801.525 kb on - strand at 1801.525 kb on - strand at 1801.525 kb on - strand at 1801.525 kb on - strand at 1801.525 kb on - strand at 1801.525 kb on - strand at 1801.591 kb on - strand at 1801.638 kb on - strand at 1801.726 kb on - strand, within PfGW456L13_1641 at 1801.726 kb on - strand, within PfGW456L13_1641 at 1801.728 kb on + strand, within PfGW456L13_1641 at 1801.729 kb on - strand, within PfGW456L13_1641 at 1801.729 kb on - strand, within PfGW456L13_1641 at 1801.729 kb on - strand, within PfGW456L13_1641 at 1801.729 kb on - strand, within PfGW456L13_1641 at 1801.729 kb on - strand, within PfGW456L13_1641 at 1801.729 kb on - strand, within PfGW456L13_1641 at 1801.827 kb on - strand, within PfGW456L13_1641 at 1801.827 kb on - strand, within PfGW456L13_1641 at 1801.827 kb on - strand, within PfGW456L13_1641 at 1801.830 kb on - strand, within PfGW456L13_1641 at 1801.830 kb on - strand, within PfGW456L13_1641 at 1801.830 kb on - strand, within PfGW456L13_1641 at 1801.830 kb on - strand, within PfGW456L13_1641 at 1801.830 kb on - strand, within PfGW456L13_1641 at 1801.830 kb on - strand, within PfGW456L13_1641 at 1801.835 kb on - strand, within PfGW456L13_1641 at 1801.845 kb on - strand at 1801.845 kb on - strand, within PfGW456L13_1641 at 1801.873 kb on + strand, within PfGW456L13_1641 at 1802.035 kb on + strand at 1802.035 kb on + strand at 1802.035 kb on + strand at 1802.036 kb on - strand at 1802.145 kb on - strand at 1802.165 kb on + strand, within PfGW456L13_1642 at 1802.221 kb on + strand, within PfGW456L13_1642 at 1802.285 kb on + strand, within PfGW456L13_1642 at 1802.285 kb on + strand, within PfGW456L13_1642 at 1802.286 kb on - strand, within PfGW456L13_1642 at 1802.286 kb on - strand, within PfGW456L13_1642 at 1802.330 kb on + strand, within PfGW456L13_1642 at 1802.351 kb on + strand, within PfGW456L13_1642 at 1802.352 kb on - strand, within PfGW456L13_1642 at 1802.352 kb on - strand, within PfGW456L13_1642 at 1802.762 kb on + strand, within PfGW456L13_1642 at 1802.957 kb on + strand, within PfGW456L13_1642 at 1802.957 kb on + strand, within PfGW456L13_1642 at 1803.422 kb on + strand, within PfGW456L13_1642 at 1803.422 kb on + strand, within PfGW456L13_1642 at 1803.422 kb on + strand, within PfGW456L13_1642 at 1803.422 kb on + strand, within PfGW456L13_1642 at 1803.422 kb on + strand, within PfGW456L13_1642 at 1803.423 kb on - strand, within PfGW456L13_1642 at 1803.423 kb on - strand, within PfGW456L13_1642 at 1803.423 kb on - strand, within PfGW456L13_1642 at 1803.423 kb on - strand, within PfGW456L13_1642 at 1803.591 kb on - strand, within PfGW456L13_1642 at 1803.791 kb on + strand at 1803.791 kb on + strand at 1803.791 kb on + strand at 1803.791 kb on + strand at 1803.792 kb on - strand at 1803.792 kb on - strand at 1803.792 kb on - strand at 1803.792 kb on - strand at 1803.792 kb on - strand at 1803.792 kb on - strand at 1803.792 kb on - strand at 1803.792 kb on - strand at 1803.804 kb on + strand at 1803.805 kb on - strand at 1803.830 kb on + strand at 1803.858 kb on + strand at 1803.858 kb on + strand at 1803.859 kb on - strand at 1803.880 kb on + strand at 1803.880 kb on + strand at 1803.880 kb on + strand at 1803.881 kb on - strand at 1803.881 kb on - strand at 1803.881 kb on - strand at 1803.889 kb on + strand at 1803.889 kb on + strand at 1803.889 kb on + strand at 1803.889 kb on + strand at 1803.889 kb on + strand at 1803.890 kb on - strand at 1803.890 kb on - strand at 1803.890 kb on - strand at 1803.890 kb on - strand at 1803.890 kb on - strand at 1803.922 kb on + strand at 1803.923 kb on - strand at 1803.964 kb on - strand at 1804.042 kb on + strand at 1804.042 kb on + strand at 1804.042 kb on + strand at 1804.042 kb on + strand at 1804.042 kb on + strand at 1804.042 kb on + strand at 1804.042 kb on + strand at 1804.042 kb on + strand at 1804.043 kb on - strand at 1804.043 kb on - strand at 1804.043 kb on - strand at 1804.043 kb on - strand at 1804.043 kb on - strand at 1804.221 kb on + strand, within PfGW456L13_1643 at 1804.221 kb on + strand, within PfGW456L13_1643 at 1804.222 kb on - strand, within PfGW456L13_1643 at 1804.230 kb on + strand, within PfGW456L13_1643 at 1804.231 kb on - strand, within PfGW456L13_1643 at 1804.341 kb on + strand, within PfGW456L13_1643 at 1804.341 kb on + strand, within PfGW456L13_1643 at 1804.341 kb on + strand, within PfGW456L13_1643 at 1804.342 kb on - strand, within PfGW456L13_1643 at 1804.346 kb on + strand, within PfGW456L13_1643 at 1804.346 kb on + strand, within PfGW456L13_1643 at 1804.347 kb on - strand, within PfGW456L13_1643 at 1804.418 kb on + strand, within PfGW456L13_1643 at 1804.418 kb on + strand, within PfGW456L13_1643 at 1804.419 kb on - strand, within PfGW456L13_1643 at 1804.475 kb on + strand, within PfGW456L13_1643 at 1804.475 kb on + strand, within PfGW456L13_1643 at 1804.504 kb on + strand, within PfGW456L13_1643 at 1804.504 kb on + strand, within PfGW456L13_1643 at 1804.505 kb on - strand, within PfGW456L13_1643 at 1804.505 kb on - strand, within PfGW456L13_1643 at 1804.688 kb on + strand, within PfGW456L13_1643 at 1804.688 kb on + strand, within PfGW456L13_1643
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.5 mg/ml remove 1,801,525 - +0.8 1,801,525 - +2.1 1,801,525 - -1.0 1,801,525 - -0.9 1,801,525 - +0.1 1,801,525 - -0.7 1,801,591 - -2.2 1,801,638 - -0.8 1,801,726 - PfGW456L13_1641 0.30 -0.2 1,801,726 - PfGW456L13_1641 0.30 -0.9 1,801,728 + PfGW456L13_1641 0.31 -1.4 1,801,729 - PfGW456L13_1641 0.31 -0.6 1,801,729 - PfGW456L13_1641 0.31 +1.5 1,801,729 - PfGW456L13_1641 0.31 +0.1 1,801,729 - PfGW456L13_1641 0.31 +0.8 1,801,729 - PfGW456L13_1641 0.31 -0.3 1,801,729 - PfGW456L13_1641 0.31 +0.3 1,801,827 - PfGW456L13_1641 0.58 +0.2 1,801,827 - PfGW456L13_1641 0.58 -1.3 1,801,827 - PfGW456L13_1641 0.58 -1.3 1,801,830 - PfGW456L13_1641 0.59 -3.1 1,801,830 - PfGW456L13_1641 0.59 -2.6 1,801,830 - PfGW456L13_1641 0.59 +0.1 1,801,830 - PfGW456L13_1641 0.59 -0.6 1,801,830 - PfGW456L13_1641 0.59 -1.4 1,801,830 - PfGW456L13_1641 0.59 +0.3 1,801,835 - PfGW456L13_1641 0.60 -2.0 1,801,845 - +2.3 1,801,845 - PfGW456L13_1641 0.63 -0.3 1,801,873 + PfGW456L13_1641 0.71 +0.4 1,802,035 + -2.4 1,802,035 + -0.9 1,802,035 + +1.6 1,802,036 - -2.5 1,802,145 - -1.0 1,802,165 + PfGW456L13_1642 0.10 -0.0 1,802,221 + PfGW456L13_1642 0.13 -0.7 1,802,285 + PfGW456L13_1642 0.17 -2.0 1,802,285 + PfGW456L13_1642 0.17 -2.4 1,802,286 - PfGW456L13_1642 0.17 -2.4 1,802,286 - PfGW456L13_1642 0.17 -3.8 1,802,330 + PfGW456L13_1642 0.19 -0.4 1,802,351 + PfGW456L13_1642 0.21 -2.4 1,802,352 - PfGW456L13_1642 0.21 -1.3 1,802,352 - PfGW456L13_1642 0.21 -0.8 1,802,762 + PfGW456L13_1642 0.43 -0.4 1,802,957 + PfGW456L13_1642 0.54 -0.7 1,802,957 + PfGW456L13_1642 0.54 +0.4 1,803,422 + PfGW456L13_1642 0.80 -0.9 1,803,422 + PfGW456L13_1642 0.80 -1.5 1,803,422 + PfGW456L13_1642 0.80 -1.4 1,803,422 + PfGW456L13_1642 0.80 -1.0 1,803,422 + PfGW456L13_1642 0.80 -1.9 1,803,423 - PfGW456L13_1642 0.80 -1.9 1,803,423 - PfGW456L13_1642 0.80 -3.0 1,803,423 - PfGW456L13_1642 0.80 -2.2 1,803,423 - PfGW456L13_1642 0.80 -0.4 1,803,591 - PfGW456L13_1642 0.89 -1.6 1,803,791 + -3.0 1,803,791 + -2.6 1,803,791 + -0.8 1,803,791 + -1.6 1,803,792 - -0.9 1,803,792 - -0.0 1,803,792 - -0.5 1,803,792 - -2.4 1,803,792 - -0.2 1,803,792 - -1.2 1,803,792 - -2.2 1,803,792 - -0.6 1,803,804 + -0.4 1,803,805 - -0.2 1,803,830 + -2.2 1,803,858 + -0.5 1,803,858 + -0.2 1,803,859 - -2.0 1,803,880 + -1.1 1,803,880 + +0.1 1,803,880 + -1.9 1,803,881 - -1.8 1,803,881 - -0.4 1,803,881 - +0.8 1,803,889 + +0.2 1,803,889 + -1.2 1,803,889 + -0.0 1,803,889 + -1.7 1,803,889 + -1.2 1,803,890 - -0.3 1,803,890 - -0.7 1,803,890 - -0.6 1,803,890 - -1.4 1,803,890 - -0.6 1,803,922 + -0.0 1,803,923 - -1.3 1,803,964 - -1.3 1,804,042 + -0.4 1,804,042 + -0.5 1,804,042 + -0.6 1,804,042 + +0.5 1,804,042 + -0.1 1,804,042 + +1.0 1,804,042 + +0.1 1,804,042 + +1.4 1,804,043 - -0.6 1,804,043 - -1.4 1,804,043 - +1.0 1,804,043 - -1.0 1,804,043 - -0.2 1,804,221 + PfGW456L13_1643 0.25 +0.2 1,804,221 + PfGW456L13_1643 0.25 +0.0 1,804,222 - PfGW456L13_1643 0.25 +2.5 1,804,230 + PfGW456L13_1643 0.26 +0.8 1,804,231 - PfGW456L13_1643 0.26 +0.4 1,804,341 + PfGW456L13_1643 0.39 -0.0 1,804,341 + PfGW456L13_1643 0.39 +0.8 1,804,341 + PfGW456L13_1643 0.39 +1.0 1,804,342 - PfGW456L13_1643 0.39 -1.6 1,804,346 + PfGW456L13_1643 0.40 -0.5 1,804,346 + PfGW456L13_1643 0.40 +2.3 1,804,347 - PfGW456L13_1643 0.40 -1.3 1,804,418 + PfGW456L13_1643 0.48 -0.5 1,804,418 + PfGW456L13_1643 0.48 +0.5 1,804,419 - PfGW456L13_1643 0.48 -0.8 1,804,475 + PfGW456L13_1643 0.54 -0.1 1,804,475 + PfGW456L13_1643 0.54 +0.4 1,804,504 + PfGW456L13_1643 0.58 +0.6 1,804,504 + PfGW456L13_1643 0.58 -1.9 1,804,505 - PfGW456L13_1643 0.58 +0.3 1,804,505 - PfGW456L13_1643 0.58 +0.1 1,804,688 + PfGW456L13_1643 0.79 +1.2 1,804,688 + PfGW456L13_1643 0.79 +3.3
Or see this region's nucleotide sequence