Experiment: Vancomycin 0.5 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_1538 and PfGW456L13_1539 are separated by 2 nucleotides PfGW456L13_1539 and PfGW456L13_1540 are separated by 45 nucleotides
PfGW456L13_1538 - Acetolactate synthase large subunit (EC 2.2.1.6), at 1,691,913 to 1,693,613
_1538
PfGW456L13_1539 - Acetolactate synthase small subunit (EC 2.2.1.6), at 1,693,616 to 1,694,107
_1539
PfGW456L13_1540 - Ketol-acid reductoisomerase (EC 1.1.1.86), at 1,694,153 to 1,695,169
_1540
Position (kb)
1693
1694
1695 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2
3 at 1692.678 kb on + strand, within PfGW456L13_1538 at 1692.678 kb on + strand, within PfGW456L13_1538 at 1692.678 kb on + strand, within PfGW456L13_1538 at 1692.845 kb on + strand, within PfGW456L13_1538 at 1692.985 kb on - strand, within PfGW456L13_1538 at 1693.110 kb on + strand, within PfGW456L13_1538 at 1693.110 kb on + strand, within PfGW456L13_1538 at 1693.110 kb on + strand, within PfGW456L13_1538 at 1693.111 kb on - strand, within PfGW456L13_1538 at 1693.111 kb on - strand, within PfGW456L13_1538 at 1693.111 kb on - strand, within PfGW456L13_1538 at 1693.204 kb on - strand, within PfGW456L13_1538 at 1693.204 kb on - strand, within PfGW456L13_1538 at 1693.284 kb on + strand, within PfGW456L13_1538 at 1693.284 kb on + strand, within PfGW456L13_1538 at 1693.297 kb on + strand, within PfGW456L13_1538 at 1693.359 kb on + strand, within PfGW456L13_1538 at 1693.359 kb on + strand, within PfGW456L13_1538 at 1693.359 kb on + strand, within PfGW456L13_1538 at 1693.359 kb on + strand, within PfGW456L13_1538 at 1693.360 kb on - strand, within PfGW456L13_1538 at 1693.360 kb on - strand, within PfGW456L13_1538 at 1693.360 kb on - strand, within PfGW456L13_1538 at 1693.360 kb on - strand, within PfGW456L13_1538 at 1693.360 kb on - strand, within PfGW456L13_1538 at 1693.360 kb on - strand, within PfGW456L13_1538 at 1693.383 kb on + strand, within PfGW456L13_1538 at 1693.383 kb on + strand, within PfGW456L13_1538 at 1693.383 kb on + strand, within PfGW456L13_1538 at 1693.383 kb on + strand, within PfGW456L13_1538 at 1693.383 kb on + strand, within PfGW456L13_1538 at 1693.383 kb on + strand, within PfGW456L13_1538 at 1693.384 kb on - strand, within PfGW456L13_1538 at 1693.384 kb on - strand, within PfGW456L13_1538 at 1693.384 kb on - strand, within PfGW456L13_1538 at 1693.384 kb on - strand, within PfGW456L13_1538 at 1693.425 kb on + strand, within PfGW456L13_1538 at 1693.425 kb on + strand, within PfGW456L13_1538 at 1693.425 kb on + strand, within PfGW456L13_1538 at 1693.425 kb on + strand, within PfGW456L13_1538 at 1693.426 kb on - strand, within PfGW456L13_1538 at 1693.426 kb on - strand, within PfGW456L13_1538 at 1693.426 kb on - strand, within PfGW456L13_1538 at 1693.426 kb on - strand, within PfGW456L13_1538 at 1693.520 kb on + strand at 1693.583 kb on + strand at 1693.583 kb on + strand at 1693.583 kb on + strand at 1693.583 kb on + strand at 1693.583 kb on + strand at 1693.583 kb on + strand at 1693.583 kb on + strand at 1693.584 kb on - strand at 1693.584 kb on - strand at 1693.607 kb on + strand at 1693.607 kb on + strand at 1693.607 kb on + strand at 1693.607 kb on + strand at 1693.607 kb on + strand at 1693.607 kb on + strand at 1693.607 kb on + strand at 1693.607 kb on + strand at 1693.608 kb on - strand at 1693.611 kb on + strand at 1693.611 kb on + strand at 1693.611 kb on + strand at 1693.611 kb on + strand at 1693.611 kb on + strand at 1693.612 kb on - strand at 1693.627 kb on + strand at 1693.627 kb on + strand at 1693.627 kb on + strand at 1693.627 kb on + strand at 1693.628 kb on - strand at 1693.628 kb on - strand at 1693.628 kb on - strand at 1693.697 kb on + strand, within PfGW456L13_1539 at 1693.697 kb on + strand, within PfGW456L13_1539 at 1693.697 kb on + strand, within PfGW456L13_1539 at 1693.697 kb on + strand, within PfGW456L13_1539 at 1693.697 kb on + strand, within PfGW456L13_1539 at 1693.697 kb on + strand, within PfGW456L13_1539 at 1693.697 kb on + strand, within PfGW456L13_1539 at 1693.697 kb on + strand, within PfGW456L13_1539 at 1693.697 kb on + strand, within PfGW456L13_1539 at 1693.698 kb on - strand, within PfGW456L13_1539 at 1693.698 kb on - strand, within PfGW456L13_1539 at 1693.698 kb on - strand, within PfGW456L13_1539 at 1693.698 kb on - strand, within PfGW456L13_1539 at 1693.698 kb on - strand, within PfGW456L13_1539 at 1693.698 kb on - strand, within PfGW456L13_1539 at 1693.827 kb on + strand, within PfGW456L13_1539 at 1693.828 kb on - strand, within PfGW456L13_1539 at 1693.828 kb on - strand, within PfGW456L13_1539 at 1693.928 kb on - strand, within PfGW456L13_1539 at 1693.934 kb on - strand, within PfGW456L13_1539 at 1693.934 kb on - strand, within PfGW456L13_1539 at 1693.937 kb on + strand, within PfGW456L13_1539 at 1693.937 kb on + strand, within PfGW456L13_1539 at 1693.937 kb on + strand, within PfGW456L13_1539 at 1693.938 kb on - strand, within PfGW456L13_1539 at 1693.938 kb on - strand, within PfGW456L13_1539 at 1693.938 kb on - strand, within PfGW456L13_1539 at 1693.938 kb on - strand, within PfGW456L13_1539 at 1693.973 kb on + strand, within PfGW456L13_1539 at 1693.973 kb on + strand, within PfGW456L13_1539 at 1693.973 kb on + strand, within PfGW456L13_1539 at 1693.974 kb on - strand, within PfGW456L13_1539 at 1693.974 kb on - strand, within PfGW456L13_1539 at 1693.974 kb on - strand, within PfGW456L13_1539 at 1693.974 kb on - strand, within PfGW456L13_1539 at 1693.974 kb on - strand, within PfGW456L13_1539 at 1693.974 kb on - strand, within PfGW456L13_1539 at 1693.974 kb on - strand, within PfGW456L13_1539 at 1693.974 kb on - strand, within PfGW456L13_1539 at 1693.976 kb on - strand, within PfGW456L13_1539 at 1694.094 kb on + strand at 1694.094 kb on + strand at 1694.094 kb on + strand at 1694.094 kb on + strand at 1694.094 kb on + strand at 1694.094 kb on + strand at 1694.094 kb on + strand at 1694.095 kb on - strand at 1694.095 kb on - strand at 1694.095 kb on - strand at 1694.095 kb on - strand at 1694.095 kb on - strand at 1694.095 kb on - strand at 1694.095 kb on - strand at 1694.106 kb on - strand at 1694.106 kb on - strand at 1694.139 kb on + strand at 1694.139 kb on + strand at 1694.139 kb on + strand at 1694.139 kb on + strand at 1694.139 kb on + strand at 1694.140 kb on - strand at 1694.140 kb on - strand at 1694.141 kb on + strand at 1694.141 kb on + strand at 1694.141 kb on + strand at 1694.141 kb on + strand at 1694.142 kb on - strand at 1694.142 kb on - strand at 1694.142 kb on - strand at 1694.142 kb on - strand at 1694.222 kb on + strand at 1694.293 kb on + strand, within PfGW456L13_1540 at 1694.417 kb on + strand, within PfGW456L13_1540 at 1694.417 kb on + strand, within PfGW456L13_1540 at 1694.418 kb on - strand, within PfGW456L13_1540 at 1694.418 kb on - strand, within PfGW456L13_1540 at 1694.418 kb on - strand, within PfGW456L13_1540 at 1694.418 kb on - strand, within PfGW456L13_1540 at 1694.489 kb on + strand, within PfGW456L13_1540 at 1694.490 kb on - strand, within PfGW456L13_1540 at 1694.490 kb on - strand, within PfGW456L13_1540 at 1694.490 kb on - strand, within PfGW456L13_1540 at 1694.559 kb on + strand, within PfGW456L13_1540 at 1694.559 kb on + strand, within PfGW456L13_1540 at 1694.559 kb on + strand, within PfGW456L13_1540 at 1694.559 kb on + strand, within PfGW456L13_1540 at 1694.559 kb on + strand, within PfGW456L13_1540 at 1694.559 kb on + strand, within PfGW456L13_1540 at 1694.559 kb on + strand, within PfGW456L13_1540 at 1694.560 kb on - strand, within PfGW456L13_1540 at 1694.560 kb on - strand, within PfGW456L13_1540 at 1694.560 kb on - strand, within PfGW456L13_1540 at 1694.560 kb on - strand, within PfGW456L13_1540 at 1694.560 kb on - strand, within PfGW456L13_1540 at 1694.560 kb on - strand, within PfGW456L13_1540 at 1694.560 kb on - strand, within PfGW456L13_1540 at 1694.560 kb on - strand, within PfGW456L13_1540 at 1694.605 kb on + strand, within PfGW456L13_1540 at 1694.610 kb on - strand, within PfGW456L13_1540 at 1694.651 kb on + strand, within PfGW456L13_1540 at 1694.651 kb on + strand, within PfGW456L13_1540 at 1694.804 kb on + strand, within PfGW456L13_1540 at 1694.823 kb on - strand, within PfGW456L13_1540 at 1694.823 kb on - strand, within PfGW456L13_1540 at 1694.823 kb on - strand, within PfGW456L13_1540 at 1694.867 kb on + strand, within PfGW456L13_1540 at 1694.867 kb on + strand, within PfGW456L13_1540 at 1694.867 kb on + strand, within PfGW456L13_1540 at 1694.867 kb on + strand, within PfGW456L13_1540 at 1694.867 kb on + strand, within PfGW456L13_1540 at 1694.867 kb on + strand, within PfGW456L13_1540 at 1694.867 kb on + strand, within PfGW456L13_1540 at 1694.867 kb on + strand, within PfGW456L13_1540 at 1694.868 kb on - strand, within PfGW456L13_1540 at 1694.868 kb on - strand, within PfGW456L13_1540 at 1694.894 kb on + strand, within PfGW456L13_1540 at 1694.894 kb on + strand, within PfGW456L13_1540 at 1694.894 kb on + strand, within PfGW456L13_1540 at 1694.895 kb on - strand, within PfGW456L13_1540 at 1694.895 kb on - strand, within PfGW456L13_1540 at 1694.895 kb on - strand, within PfGW456L13_1540 at 1694.895 kb on - strand, within PfGW456L13_1540 at 1694.895 kb on - strand, within PfGW456L13_1540 at 1694.895 kb on - strand, within PfGW456L13_1540 at 1694.927 kb on + strand, within PfGW456L13_1540 at 1694.927 kb on + strand, within PfGW456L13_1540 at 1694.992 kb on + strand, within PfGW456L13_1540 at 1694.993 kb on - strand, within PfGW456L13_1540 at 1695.009 kb on - strand, within PfGW456L13_1540 at 1695.070 kb on + strand at 1695.070 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.5 mg/ml remove 1,692,678 + PfGW456L13_1538 0.45 -0.6 1,692,678 + PfGW456L13_1538 0.45 -3.1 1,692,678 + PfGW456L13_1538 0.45 -1.3 1,692,845 + PfGW456L13_1538 0.55 -1.2 1,692,985 - PfGW456L13_1538 0.63 -2.8 1,693,110 + PfGW456L13_1538 0.70 -3.7 1,693,110 + PfGW456L13_1538 0.70 -3.0 1,693,110 + PfGW456L13_1538 0.70 -2.6 1,693,111 - PfGW456L13_1538 0.70 -3.0 1,693,111 - PfGW456L13_1538 0.70 -2.4 1,693,111 - PfGW456L13_1538 0.70 -2.7 1,693,204 - PfGW456L13_1538 0.76 -0.3 1,693,204 - PfGW456L13_1538 0.76 -2.0 1,693,284 + PfGW456L13_1538 0.81 -1.3 1,693,284 + PfGW456L13_1538 0.81 -0.0 1,693,297 + PfGW456L13_1538 0.81 -0.0 1,693,359 + PfGW456L13_1538 0.85 -3.3 1,693,359 + PfGW456L13_1538 0.85 -1.3 1,693,359 + PfGW456L13_1538 0.85 -1.6 1,693,359 + PfGW456L13_1538 0.85 -1.8 1,693,360 - PfGW456L13_1538 0.85 -0.9 1,693,360 - PfGW456L13_1538 0.85 -1.3 1,693,360 - PfGW456L13_1538 0.85 -2.2 1,693,360 - PfGW456L13_1538 0.85 -2.0 1,693,360 - PfGW456L13_1538 0.85 -1.7 1,693,360 - PfGW456L13_1538 0.85 -2.5 1,693,383 + PfGW456L13_1538 0.86 -0.9 1,693,383 + PfGW456L13_1538 0.86 -3.3 1,693,383 + PfGW456L13_1538 0.86 -1.3 1,693,383 + PfGW456L13_1538 0.86 -3.3 1,693,383 + PfGW456L13_1538 0.86 -2.0 1,693,383 + PfGW456L13_1538 0.86 -2.7 1,693,384 - PfGW456L13_1538 0.86 -0.0 1,693,384 - PfGW456L13_1538 0.86 -0.0 1,693,384 - PfGW456L13_1538 0.86 -1.6 1,693,384 - PfGW456L13_1538 0.86 -1.6 1,693,425 + PfGW456L13_1538 0.89 -2.3 1,693,425 + PfGW456L13_1538 0.89 -1.2 1,693,425 + PfGW456L13_1538 0.89 -0.0 1,693,425 + PfGW456L13_1538 0.89 -1.9 1,693,426 - PfGW456L13_1538 0.89 -1.6 1,693,426 - PfGW456L13_1538 0.89 -1.7 1,693,426 - PfGW456L13_1538 0.89 -3.3 1,693,426 - PfGW456L13_1538 0.89 -0.6 1,693,520 + -1.8 1,693,583 + -1.0 1,693,583 + -0.6 1,693,583 + +0.1 1,693,583 + +1.2 1,693,583 + -0.2 1,693,583 + +0.7 1,693,583 + -0.1 1,693,584 - -0.3 1,693,584 - -2.0 1,693,607 + +0.7 1,693,607 + +0.7 1,693,607 + -0.8 1,693,607 + -0.2 1,693,607 + -2.0 1,693,607 + +0.1 1,693,607 + -0.3 1,693,607 + -0.5 1,693,608 - -2.8 1,693,611 + +0.1 1,693,611 + +0.2 1,693,611 + -1.5 1,693,611 + -1.0 1,693,611 + -1.1 1,693,612 - -0.8 1,693,627 + -3.3 1,693,627 + -2.2 1,693,627 + -3.7 1,693,627 + -1.0 1,693,628 - -0.8 1,693,628 - -2.9 1,693,628 - -1.3 1,693,697 + PfGW456L13_1539 0.16 -1.7 1,693,697 + PfGW456L13_1539 0.16 -2.7 1,693,697 + PfGW456L13_1539 0.16 -3.5 1,693,697 + PfGW456L13_1539 0.16 -1.1 1,693,697 + PfGW456L13_1539 0.16 -2.0 1,693,697 + PfGW456L13_1539 0.16 -1.2 1,693,697 + PfGW456L13_1539 0.16 -2.9 1,693,697 + PfGW456L13_1539 0.16 -1.3 1,693,697 + PfGW456L13_1539 0.16 -0.9 1,693,698 - PfGW456L13_1539 0.17 -1.6 1,693,698 - PfGW456L13_1539 0.17 -3.3 1,693,698 - PfGW456L13_1539 0.17 -1.3 1,693,698 - PfGW456L13_1539 0.17 -2.2 1,693,698 - PfGW456L13_1539 0.17 -2.5 1,693,698 - PfGW456L13_1539 0.17 -1.0 1,693,827 + PfGW456L13_1539 0.43 -1.6 1,693,828 - PfGW456L13_1539 0.43 -2.8 1,693,828 - PfGW456L13_1539 0.43 -3.1 1,693,928 - PfGW456L13_1539 0.63 -2.7 1,693,934 - PfGW456L13_1539 0.65 -1.8 1,693,934 - PfGW456L13_1539 0.65 -1.1 1,693,937 + PfGW456L13_1539 0.65 -2.1 1,693,937 + PfGW456L13_1539 0.65 +0.8 1,693,937 + PfGW456L13_1539 0.65 +0.1 1,693,938 - PfGW456L13_1539 0.65 -1.5 1,693,938 - PfGW456L13_1539 0.65 -1.1 1,693,938 - PfGW456L13_1539 0.65 -1.2 1,693,938 - PfGW456L13_1539 0.65 -2.3 1,693,973 + PfGW456L13_1539 0.73 -2.4 1,693,973 + PfGW456L13_1539 0.73 +0.2 1,693,973 + PfGW456L13_1539 0.73 -0.7 1,693,974 - PfGW456L13_1539 0.73 -1.8 1,693,974 - PfGW456L13_1539 0.73 -1.9 1,693,974 - PfGW456L13_1539 0.73 -1.1 1,693,974 - PfGW456L13_1539 0.73 -2.6 1,693,974 - PfGW456L13_1539 0.73 -1.3 1,693,974 - PfGW456L13_1539 0.73 -1.8 1,693,974 - PfGW456L13_1539 0.73 -2.3 1,693,974 - PfGW456L13_1539 0.73 -2.3 1,693,976 - PfGW456L13_1539 0.73 -3.1 1,694,094 + +0.2 1,694,094 + -0.5 1,694,094 + +0.1 1,694,094 + -0.9 1,694,094 + -0.0 1,694,094 + +0.9 1,694,094 + -0.8 1,694,095 - +0.7 1,694,095 - +3.0 1,694,095 - +0.6 1,694,095 - -2.3 1,694,095 - +0.1 1,694,095 - +0.4 1,694,095 - +0.9 1,694,106 - +0.1 1,694,106 - -2.0 1,694,139 + -0.0 1,694,139 + -0.5 1,694,139 + -0.0 1,694,139 + -0.8 1,694,139 + -0.6 1,694,140 - -0.2 1,694,140 - -0.9 1,694,141 + -0.6 1,694,141 + +0.3 1,694,141 + -0.0 1,694,141 + +1.1 1,694,142 - -0.5 1,694,142 - +0.2 1,694,142 - -0.2 1,694,142 - -0.1 1,694,222 + +0.5 1,694,293 + PfGW456L13_1540 0.14 -0.6 1,694,417 + PfGW456L13_1540 0.26 +1.7 1,694,417 + PfGW456L13_1540 0.26 -0.0 1,694,418 - PfGW456L13_1540 0.26 +0.4 1,694,418 - PfGW456L13_1540 0.26 -0.3 1,694,418 - PfGW456L13_1540 0.26 +0.2 1,694,418 - PfGW456L13_1540 0.26 -0.7 1,694,489 + PfGW456L13_1540 0.33 -0.9 1,694,490 - PfGW456L13_1540 0.33 +0.2 1,694,490 - PfGW456L13_1540 0.33 -0.2 1,694,490 - PfGW456L13_1540 0.33 -0.2 1,694,559 + PfGW456L13_1540 0.40 -1.0 1,694,559 + PfGW456L13_1540 0.40 +0.7 1,694,559 + PfGW456L13_1540 0.40 +2.2 1,694,559 + PfGW456L13_1540 0.40 +1.4 1,694,559 + PfGW456L13_1540 0.40 +0.6 1,694,559 + PfGW456L13_1540 0.40 +0.7 1,694,559 + PfGW456L13_1540 0.40 +0.4 1,694,560 - PfGW456L13_1540 0.40 +0.2 1,694,560 - PfGW456L13_1540 0.40 -1.3 1,694,560 - PfGW456L13_1540 0.40 -1.6 1,694,560 - PfGW456L13_1540 0.40 +0.1 1,694,560 - PfGW456L13_1540 0.40 +0.3 1,694,560 - PfGW456L13_1540 0.40 +0.6 1,694,560 - PfGW456L13_1540 0.40 +0.4 1,694,560 - PfGW456L13_1540 0.40 +0.9 1,694,605 + PfGW456L13_1540 0.44 +1.3 1,694,610 - PfGW456L13_1540 0.45 +0.0 1,694,651 + PfGW456L13_1540 0.49 +0.5 1,694,651 + PfGW456L13_1540 0.49 -0.0 1,694,804 + PfGW456L13_1540 0.64 +0.5 1,694,823 - PfGW456L13_1540 0.66 -1.4 1,694,823 - PfGW456L13_1540 0.66 -0.0 1,694,823 - PfGW456L13_1540 0.66 -0.0 1,694,867 + PfGW456L13_1540 0.70 +0.5 1,694,867 + PfGW456L13_1540 0.70 -0.4 1,694,867 + PfGW456L13_1540 0.70 -0.5 1,694,867 + PfGW456L13_1540 0.70 -0.6 1,694,867 + PfGW456L13_1540 0.70 +0.6 1,694,867 + PfGW456L13_1540 0.70 +0.2 1,694,867 + PfGW456L13_1540 0.70 -2.0 1,694,867 + PfGW456L13_1540 0.70 +0.5 1,694,868 - PfGW456L13_1540 0.70 -1.0 1,694,868 - PfGW456L13_1540 0.70 +0.1 1,694,894 + PfGW456L13_1540 0.73 +0.8 1,694,894 + PfGW456L13_1540 0.73 -0.9 1,694,894 + PfGW456L13_1540 0.73 +0.2 1,694,895 - PfGW456L13_1540 0.73 +0.8 1,694,895 - PfGW456L13_1540 0.73 -0.4 1,694,895 - PfGW456L13_1540 0.73 -1.1 1,694,895 - PfGW456L13_1540 0.73 -1.6 1,694,895 - PfGW456L13_1540 0.73 +0.3 1,694,895 - PfGW456L13_1540 0.73 +0.4 1,694,927 + PfGW456L13_1540 0.76 +0.5 1,694,927 + PfGW456L13_1540 0.76 +0.3 1,694,992 + PfGW456L13_1540 0.82 +1.1 1,694,993 - PfGW456L13_1540 0.83 -2.7 1,695,009 - PfGW456L13_1540 0.84 -2.0 1,695,070 + +0.5 1,695,070 + -0.3
Or see this region's nucleotide sequence