Experiment: Vancomycin 0.5 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_1190 and PfGW456L13_1191 are separated by 83 nucleotides PfGW456L13_1191 and PfGW456L13_1192 overlap by 10 nucleotides PfGW456L13_1192 and PfGW456L13_1193 are separated by 81 nucleotides
PfGW456L13_1190 - Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY, at 1,328,719 to 1,329,288
_1190
PfGW456L13_1191 - Dihydroneopterin aldolase (EC 4.1.2.25), at 1,329,372 to 1,329,719
_1191
PfGW456L13_1192 - 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3), at 1,329,710 to 1,330,228
_1192
PfGW456L13_1193 - tRNA nucleotidyltransferase (EC 2.7.7.21) (EC 2.7.7.25), at 1,330,310 to 1,331,539
_1193
Position (kb)
1329
1330
1331 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 1328.755 kb on + strand at 1328.756 kb on - strand at 1328.883 kb on + strand, within PfGW456L13_1190 at 1328.894 kb on + strand, within PfGW456L13_1190 at 1328.894 kb on + strand, within PfGW456L13_1190 at 1328.894 kb on + strand, within PfGW456L13_1190 at 1328.895 kb on - strand, within PfGW456L13_1190 at 1328.895 kb on - strand, within PfGW456L13_1190 at 1328.895 kb on - strand, within PfGW456L13_1190 at 1328.895 kb on - strand, within PfGW456L13_1190 at 1328.943 kb on - strand, within PfGW456L13_1190 at 1329.002 kb on + strand, within PfGW456L13_1190 at 1329.002 kb on + strand, within PfGW456L13_1190 at 1329.002 kb on + strand, within PfGW456L13_1190 at 1329.003 kb on - strand, within PfGW456L13_1190 at 1329.003 kb on - strand, within PfGW456L13_1190 at 1329.003 kb on - strand, within PfGW456L13_1190 at 1329.032 kb on + strand, within PfGW456L13_1190 at 1329.032 kb on + strand, within PfGW456L13_1190 at 1329.032 kb on + strand, within PfGW456L13_1190 at 1329.032 kb on + strand, within PfGW456L13_1190 at 1329.033 kb on - strand, within PfGW456L13_1190 at 1329.033 kb on - strand, within PfGW456L13_1190 at 1329.261 kb on - strand at 1329.278 kb on - strand at 1329.291 kb on + strand at 1329.291 kb on + strand at 1329.292 kb on - strand at 1329.292 kb on - strand at 1329.292 kb on - strand at 1329.292 kb on - strand at 1329.292 kb on - strand at 1329.292 kb on - strand at 1329.292 kb on - strand at 1329.295 kb on + strand at 1329.295 kb on + strand at 1329.296 kb on - strand at 1329.296 kb on - strand at 1329.296 kb on - strand at 1329.296 kb on - strand at 1329.296 kb on - strand at 1329.728 kb on + strand at 1329.728 kb on + strand at 1329.729 kb on - strand at 1329.729 kb on - strand at 1329.729 kb on - strand at 1329.729 kb on - strand at 1329.742 kb on + strand at 1329.888 kb on - strand, within PfGW456L13_1192 at 1329.888 kb on - strand, within PfGW456L13_1192 at 1329.993 kb on + strand, within PfGW456L13_1192 at 1329.993 kb on + strand, within PfGW456L13_1192 at 1329.993 kb on + strand, within PfGW456L13_1192 at 1329.993 kb on + strand, within PfGW456L13_1192 at 1329.994 kb on - strand, within PfGW456L13_1192 at 1329.994 kb on - strand, within PfGW456L13_1192 at 1330.180 kb on - strand at 1330.231 kb on + strand at 1330.231 kb on + strand at 1330.231 kb on + strand at 1330.232 kb on - strand at 1330.232 kb on - strand at 1330.232 kb on - strand at 1330.263 kb on - strand at 1330.275 kb on + strand at 1330.275 kb on + strand at 1330.332 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.5 mg/ml remove 1,328,755 + -1.3 1,328,756 - -0.5 1,328,883 + PfGW456L13_1190 0.29 -0.4 1,328,894 + PfGW456L13_1190 0.31 -0.6 1,328,894 + PfGW456L13_1190 0.31 +0.2 1,328,894 + PfGW456L13_1190 0.31 -1.7 1,328,895 - PfGW456L13_1190 0.31 -0.2 1,328,895 - PfGW456L13_1190 0.31 +0.7 1,328,895 - PfGW456L13_1190 0.31 +0.5 1,328,895 - PfGW456L13_1190 0.31 +1.1 1,328,943 - PfGW456L13_1190 0.39 -2.4 1,329,002 + PfGW456L13_1190 0.50 -1.3 1,329,002 + PfGW456L13_1190 0.50 -0.5 1,329,002 + PfGW456L13_1190 0.50 -0.8 1,329,003 - PfGW456L13_1190 0.50 +0.8 1,329,003 - PfGW456L13_1190 0.50 +0.3 1,329,003 - PfGW456L13_1190 0.50 -0.4 1,329,032 + PfGW456L13_1190 0.55 -0.5 1,329,032 + PfGW456L13_1190 0.55 +0.4 1,329,032 + PfGW456L13_1190 0.55 -0.7 1,329,032 + PfGW456L13_1190 0.55 +0.0 1,329,033 - PfGW456L13_1190 0.55 +0.0 1,329,033 - PfGW456L13_1190 0.55 +0.5 1,329,261 - -0.4 1,329,278 - -2.6 1,329,291 + -0.8 1,329,291 + +1.3 1,329,292 - -0.9 1,329,292 - +0.6 1,329,292 - +0.7 1,329,292 - -0.8 1,329,292 - +0.1 1,329,292 - -0.2 1,329,292 - -0.4 1,329,295 + -0.9 1,329,295 + -0.7 1,329,296 - -0.8 1,329,296 - +0.8 1,329,296 - -0.2 1,329,296 - -2.4 1,329,296 - -1.8 1,329,728 + -1.3 1,329,728 + -1.6 1,329,729 - -2.0 1,329,729 - -1.3 1,329,729 - -2.6 1,329,729 - +0.0 1,329,742 + -1.6 1,329,888 - PfGW456L13_1192 0.34 -2.0 1,329,888 - PfGW456L13_1192 0.34 -2.9 1,329,993 + PfGW456L13_1192 0.55 -1.2 1,329,993 + PfGW456L13_1192 0.55 -0.1 1,329,993 + PfGW456L13_1192 0.55 -3.1 1,329,993 + PfGW456L13_1192 0.55 -1.2 1,329,994 - PfGW456L13_1192 0.55 -3.1 1,329,994 - PfGW456L13_1192 0.55 -2.0 1,330,180 - -2.0 1,330,231 + +1.8 1,330,231 + -1.4 1,330,231 + -0.7 1,330,232 - +1.0 1,330,232 - -1.8 1,330,232 - +0.4 1,330,263 - +0.4 1,330,275 + -1.0 1,330,275 + +0.8 1,330,332 + -0.5
Or see this region's nucleotide sequence