Experiment: Vancomycin 0.5 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_1049 and PfGW456L13_1050 are separated by 193 nucleotides PfGW456L13_1050 and PfGW456L13_1051 are separated by 158 nucleotides
PfGW456L13_1049 - periplasmic binding protein, putative, at 1,163,570 to 1,164,385
_1049
PfGW456L13_1050 - 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20), at 1,164,579 to 1,165,424
_1050
PfGW456L13_1051 - Adenosylhomocysteinase (EC 3.3.1.1), at 1,165,583 to 1,166,992
_1051
Position (kb)
1164
1165
1166 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 1163.967 kb on + strand, within PfGW456L13_1049 at 1163.967 kb on + strand, within PfGW456L13_1049 at 1164.048 kb on + strand, within PfGW456L13_1049 at 1164.049 kb on - strand, within PfGW456L13_1049 at 1164.049 kb on - strand, within PfGW456L13_1049 at 1164.091 kb on - strand, within PfGW456L13_1049 at 1164.091 kb on - strand, within PfGW456L13_1049 at 1164.243 kb on + strand, within PfGW456L13_1049 at 1164.243 kb on + strand, within PfGW456L13_1049 at 1164.276 kb on + strand, within PfGW456L13_1049 at 1164.276 kb on + strand, within PfGW456L13_1049 at 1164.276 kb on + strand, within PfGW456L13_1049 at 1164.277 kb on - strand, within PfGW456L13_1049 at 1164.277 kb on - strand, within PfGW456L13_1049 at 1164.277 kb on - strand, within PfGW456L13_1049 at 1164.277 kb on - strand, within PfGW456L13_1049 at 1164.282 kb on + strand, within PfGW456L13_1049 at 1164.282 kb on + strand, within PfGW456L13_1049 at 1164.282 kb on + strand, within PfGW456L13_1049 at 1164.282 kb on + strand, within PfGW456L13_1049 at 1164.283 kb on - strand, within PfGW456L13_1049 at 1164.283 kb on - strand, within PfGW456L13_1049 at 1164.283 kb on - strand, within PfGW456L13_1049 at 1164.365 kb on + strand at 1164.365 kb on + strand at 1164.366 kb on - strand at 1164.366 kb on - strand at 1164.385 kb on + strand at 1164.385 kb on + strand at 1164.385 kb on + strand at 1164.385 kb on + strand at 1164.385 kb on + strand at 1164.385 kb on + strand at 1164.385 kb on + strand at 1164.386 kb on - strand at 1164.386 kb on - strand at 1164.386 kb on - strand at 1164.386 kb on - strand at 1164.441 kb on + strand at 1164.441 kb on + strand at 1164.441 kb on + strand at 1164.442 kb on - strand at 1164.464 kb on + strand at 1164.464 kb on + strand at 1164.464 kb on + strand at 1164.465 kb on - strand at 1164.465 kb on - strand at 1164.465 kb on - strand at 1164.465 kb on - strand at 1164.467 kb on + strand at 1164.467 kb on + strand at 1164.467 kb on + strand at 1164.467 kb on + strand at 1164.467 kb on + strand at 1164.509 kb on + strand at 1164.531 kb on + strand at 1164.532 kb on - strand at 1164.558 kb on + strand at 1164.559 kb on - strand at 1164.740 kb on - strand, within PfGW456L13_1050 at 1164.740 kb on - strand, within PfGW456L13_1050 at 1164.814 kb on + strand, within PfGW456L13_1050 at 1164.814 kb on + strand, within PfGW456L13_1050 at 1164.815 kb on - strand, within PfGW456L13_1050 at 1164.815 kb on - strand, within PfGW456L13_1050 at 1164.815 kb on - strand, within PfGW456L13_1050 at 1164.892 kb on + strand, within PfGW456L13_1050 at 1164.892 kb on + strand, within PfGW456L13_1050 at 1164.893 kb on - strand, within PfGW456L13_1050 at 1164.893 kb on - strand, within PfGW456L13_1050 at 1164.893 kb on - strand, within PfGW456L13_1050 at 1164.893 kb on - strand, within PfGW456L13_1050 at 1164.913 kb on + strand, within PfGW456L13_1050 at 1164.913 kb on + strand, within PfGW456L13_1050 at 1164.913 kb on + strand, within PfGW456L13_1050 at 1164.914 kb on - strand, within PfGW456L13_1050 at 1164.914 kb on - strand, within PfGW456L13_1050 at 1164.914 kb on - strand, within PfGW456L13_1050 at 1164.914 kb on - strand, within PfGW456L13_1050 at 1164.914 kb on - strand, within PfGW456L13_1050 at 1164.914 kb on - strand, within PfGW456L13_1050 at 1165.162 kb on + strand, within PfGW456L13_1050 at 1165.163 kb on - strand, within PfGW456L13_1050 at 1165.163 kb on - strand, within PfGW456L13_1050 at 1165.163 kb on - strand, within PfGW456L13_1050 at 1165.163 kb on - strand, within PfGW456L13_1050 at 1165.196 kb on + strand, within PfGW456L13_1050 at 1165.300 kb on + strand, within PfGW456L13_1050 at 1165.327 kb on + strand, within PfGW456L13_1050 at 1165.327 kb on + strand, within PfGW456L13_1050 at 1165.327 kb on + strand, within PfGW456L13_1050 at 1165.327 kb on + strand, within PfGW456L13_1050 at 1165.328 kb on - strand, within PfGW456L13_1050 at 1165.328 kb on - strand, within PfGW456L13_1050 at 1165.328 kb on - strand, within PfGW456L13_1050 at 1165.328 kb on - strand, within PfGW456L13_1050 at 1165.430 kb on + strand at 1165.431 kb on - strand at 1165.431 kb on - strand at 1165.431 kb on - strand at 1165.431 kb on - strand at 1165.446 kb on + strand at 1165.447 kb on - strand at 1165.468 kb on + strand at 1165.468 kb on + strand at 1165.562 kb on + strand at 1165.562 kb on + strand at 1165.563 kb on - strand at 1165.563 kb on - strand at 1165.581 kb on + strand at 1165.582 kb on - strand at 1165.582 kb on - strand at 1165.582 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.5 mg/ml remove 1,163,967 + PfGW456L13_1049 0.49 -0.3 1,163,967 + PfGW456L13_1049 0.49 +0.1 1,164,048 + PfGW456L13_1049 0.59 -0.3 1,164,049 - PfGW456L13_1049 0.59 +0.2 1,164,049 - PfGW456L13_1049 0.59 +0.5 1,164,091 - PfGW456L13_1049 0.64 +0.4 1,164,091 - PfGW456L13_1049 0.64 -0.1 1,164,243 + PfGW456L13_1049 0.82 +0.1 1,164,243 + PfGW456L13_1049 0.82 +0.3 1,164,276 + PfGW456L13_1049 0.87 +1.8 1,164,276 + PfGW456L13_1049 0.87 +0.5 1,164,276 + PfGW456L13_1049 0.87 -0.2 1,164,277 - PfGW456L13_1049 0.87 -0.1 1,164,277 - PfGW456L13_1049 0.87 -1.0 1,164,277 - PfGW456L13_1049 0.87 -0.5 1,164,277 - PfGW456L13_1049 0.87 +0.2 1,164,282 + PfGW456L13_1049 0.87 -0.6 1,164,282 + PfGW456L13_1049 0.87 -0.8 1,164,282 + PfGW456L13_1049 0.87 -1.4 1,164,282 + PfGW456L13_1049 0.87 +0.0 1,164,283 - PfGW456L13_1049 0.87 -1.4 1,164,283 - PfGW456L13_1049 0.87 +1.7 1,164,283 - PfGW456L13_1049 0.87 -1.6 1,164,365 + +0.5 1,164,365 + +0.5 1,164,366 - -0.7 1,164,366 - -0.3 1,164,385 + +0.1 1,164,385 + -1.1 1,164,385 + -0.5 1,164,385 + -0.5 1,164,385 + +0.7 1,164,385 + -0.8 1,164,385 + +0.4 1,164,386 - +1.1 1,164,386 - -0.2 1,164,386 - +2.1 1,164,386 - -2.7 1,164,441 + -0.6 1,164,441 + +0.3 1,164,441 + +0.1 1,164,442 - +0.6 1,164,464 + -0.0 1,164,464 + +1.2 1,164,464 + -0.5 1,164,465 - +0.2 1,164,465 - -0.2 1,164,465 - +0.1 1,164,465 - +0.2 1,164,467 + +0.9 1,164,467 + +0.5 1,164,467 + -1.6 1,164,467 + -0.7 1,164,467 + +0.3 1,164,509 + +0.0 1,164,531 + +0.1 1,164,532 - +0.7 1,164,558 + +0.8 1,164,559 - -0.2 1,164,740 - PfGW456L13_1050 0.19 -2.4 1,164,740 - PfGW456L13_1050 0.19 +0.2 1,164,814 + PfGW456L13_1050 0.28 -1.0 1,164,814 + PfGW456L13_1050 0.28 -1.1 1,164,815 - PfGW456L13_1050 0.28 -2.4 1,164,815 - PfGW456L13_1050 0.28 -1.9 1,164,815 - PfGW456L13_1050 0.28 +0.2 1,164,892 + PfGW456L13_1050 0.37 -2.6 1,164,892 + PfGW456L13_1050 0.37 -1.5 1,164,893 - PfGW456L13_1050 0.37 -0.8 1,164,893 - PfGW456L13_1050 0.37 -1.3 1,164,893 - PfGW456L13_1050 0.37 -2.1 1,164,893 - PfGW456L13_1050 0.37 -0.8 1,164,913 + PfGW456L13_1050 0.39 -1.7 1,164,913 + PfGW456L13_1050 0.39 +0.1 1,164,913 + PfGW456L13_1050 0.39 -2.8 1,164,914 - PfGW456L13_1050 0.40 -0.9 1,164,914 - PfGW456L13_1050 0.40 -1.1 1,164,914 - PfGW456L13_1050 0.40 -0.6 1,164,914 - PfGW456L13_1050 0.40 -1.6 1,164,914 - PfGW456L13_1050 0.40 -1.1 1,164,914 - PfGW456L13_1050 0.40 -1.3 1,165,162 + PfGW456L13_1050 0.69 -0.6 1,165,163 - PfGW456L13_1050 0.69 -0.8 1,165,163 - PfGW456L13_1050 0.69 -1.4 1,165,163 - PfGW456L13_1050 0.69 -2.1 1,165,163 - PfGW456L13_1050 0.69 -0.3 1,165,196 + PfGW456L13_1050 0.73 +0.1 1,165,300 + PfGW456L13_1050 0.85 -3.0 1,165,327 + PfGW456L13_1050 0.88 -2.2 1,165,327 + PfGW456L13_1050 0.88 -1.5 1,165,327 + PfGW456L13_1050 0.88 -1.8 1,165,327 + PfGW456L13_1050 0.88 -0.2 1,165,328 - PfGW456L13_1050 0.89 -1.1 1,165,328 - PfGW456L13_1050 0.89 -0.7 1,165,328 - PfGW456L13_1050 0.89 -0.5 1,165,328 - PfGW456L13_1050 0.89 -1.0 1,165,430 + -1.8 1,165,431 - +0.8 1,165,431 - +0.3 1,165,431 - -1.5 1,165,431 - -1.0 1,165,446 + -0.2 1,165,447 - +0.4 1,165,468 + -0.5 1,165,468 + -0.9 1,165,562 + -1.2 1,165,562 + -1.1 1,165,563 - +0.5 1,165,563 - -0.5 1,165,581 + +0.1 1,165,582 - -0.1 1,165,582 - +0.7 1,165,582 - +1.1
Or see this region's nucleotide sequence