Experiment: Vancomycin 0.25 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_4599 and PfGW456L13_4600 are separated by 170 nucleotides PfGW456L13_4600 and PfGW456L13_4601 are separated by 460 nucleotides PfGW456L13_4601 and PfGW456L13_4602 are separated by 231 nucleotides
PfGW456L13_4599 - RNA polymerase associated protein RapA (EC 3.6.1.-), at 5,132,066 to 5,134,912
_4599
PfGW456L13_4600 - Major facilitator family transporter, at 5,135,083 to 5,136,432
_4600
PfGW456L13_4601 - Ferredoxin, at 5,136,893 to 5,137,066
_4601
PfGW456L13_4602 - Sensory box/GGDEF family protein, at 5,137,298 to 5,139,430
_4602
Position (kb)
5135
5136
5137 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2
3
4 at 5134.163 kb on + strand, within PfGW456L13_4599 at 5134.163 kb on + strand, within PfGW456L13_4599 at 5134.163 kb on + strand, within PfGW456L13_4599 at 5134.164 kb on - strand, within PfGW456L13_4599 at 5134.164 kb on - strand, within PfGW456L13_4599 at 5134.164 kb on - strand, within PfGW456L13_4599 at 5134.299 kb on - strand, within PfGW456L13_4599 at 5134.299 kb on - strand, within PfGW456L13_4599 at 5134.307 kb on - strand, within PfGW456L13_4599 at 5134.469 kb on + strand, within PfGW456L13_4599 at 5134.469 kb on + strand, within PfGW456L13_4599 at 5134.469 kb on + strand, within PfGW456L13_4599 at 5134.469 kb on + strand, within PfGW456L13_4599 at 5134.469 kb on + strand, within PfGW456L13_4599 at 5134.470 kb on - strand, within PfGW456L13_4599 at 5134.470 kb on - strand, within PfGW456L13_4599 at 5134.515 kb on - strand, within PfGW456L13_4599 at 5134.910 kb on + strand at 5134.930 kb on + strand at 5134.971 kb on - strand at 5134.984 kb on + strand at 5134.985 kb on - strand at 5135.043 kb on + strand at 5135.043 kb on - strand at 5135.044 kb on - strand at 5135.044 kb on - strand at 5135.051 kb on - strand at 5135.051 kb on - strand at 5135.051 kb on - strand at 5135.219 kb on + strand, within PfGW456L13_4600 at 5135.219 kb on + strand, within PfGW456L13_4600 at 5135.219 kb on + strand, within PfGW456L13_4600 at 5135.219 kb on + strand, within PfGW456L13_4600 at 5135.220 kb on - strand, within PfGW456L13_4600 at 5135.220 kb on - strand, within PfGW456L13_4600 at 5135.220 kb on - strand, within PfGW456L13_4600 at 5135.220 kb on - strand, within PfGW456L13_4600 at 5135.248 kb on - strand, within PfGW456L13_4600 at 5135.354 kb on + strand, within PfGW456L13_4600 at 5135.354 kb on + strand, within PfGW456L13_4600 at 5135.355 kb on - strand, within PfGW456L13_4600 at 5135.426 kb on + strand, within PfGW456L13_4600 at 5135.436 kb on + strand, within PfGW456L13_4600 at 5135.437 kb on - strand, within PfGW456L13_4600 at 5135.437 kb on - strand, within PfGW456L13_4600 at 5135.438 kb on + strand, within PfGW456L13_4600 at 5135.438 kb on + strand at 5135.438 kb on + strand, within PfGW456L13_4600 at 5135.439 kb on - strand, within PfGW456L13_4600 at 5135.439 kb on - strand, within PfGW456L13_4600 at 5135.439 kb on - strand, within PfGW456L13_4600 at 5135.447 kb on + strand, within PfGW456L13_4600 at 5135.447 kb on + strand, within PfGW456L13_4600 at 5135.448 kb on - strand, within PfGW456L13_4600 at 5135.467 kb on - strand, within PfGW456L13_4600 at 5135.474 kb on - strand, within PfGW456L13_4600 at 5135.474 kb on - strand, within PfGW456L13_4600 at 5135.653 kb on - strand, within PfGW456L13_4600 at 5135.696 kb on + strand, within PfGW456L13_4600 at 5135.696 kb on + strand, within PfGW456L13_4600 at 5135.696 kb on + strand, within PfGW456L13_4600 at 5135.696 kb on + strand, within PfGW456L13_4600 at 5135.696 kb on + strand, within PfGW456L13_4600 at 5135.696 kb on + strand, within PfGW456L13_4600 at 5135.696 kb on + strand, within PfGW456L13_4600 at 5135.697 kb on - strand, within PfGW456L13_4600 at 5135.697 kb on - strand, within PfGW456L13_4600 at 5135.697 kb on - strand, within PfGW456L13_4600 at 5135.697 kb on - strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.735 kb on + strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.736 kb on - strand, within PfGW456L13_4600 at 5135.941 kb on - strand, within PfGW456L13_4600 at 5136.255 kb on - strand, within PfGW456L13_4600 at 5136.447 kb on + strand at 5136.447 kb on + strand at 5136.487 kb on + strand at 5136.487 kb on + strand at 5136.487 kb on + strand at 5136.606 kb on + strand at 5136.644 kb on + strand at 5136.645 kb on - strand at 5136.650 kb on - strand at 5136.688 kb on + strand at 5136.688 kb on + strand at 5136.688 kb on + strand at 5136.688 kb on + strand at 5136.688 kb on + strand at 5136.688 kb on + strand at 5136.689 kb on - strand at 5136.689 kb on - strand at 5136.692 kb on + strand at 5136.692 kb on + strand at 5136.692 kb on + strand at 5136.692 kb on + strand at 5136.692 kb on + strand at 5136.693 kb on - strand at 5136.901 kb on + strand at 5136.902 kb on - strand at 5136.921 kb on - strand, within PfGW456L13_4601 at 5137.071 kb on + strand at 5137.071 kb on + strand at 5137.072 kb on - strand at 5137.072 kb on - strand at 5137.087 kb on + strand at 5137.092 kb on + strand at 5137.093 kb on - strand at 5137.093 kb on - strand at 5137.095 kb on + strand at 5137.096 kb on - strand at 5137.096 kb on - strand at 5137.151 kb on + strand at 5137.151 kb on + strand at 5137.151 kb on + strand at 5137.151 kb on + strand at 5137.152 kb on - strand at 5137.152 kb on - strand at 5137.152 kb on - strand at 5137.152 kb on - strand at 5137.152 kb on - strand at 5137.152 kb on - strand at 5137.152 kb on - strand at 5137.152 kb on - strand at 5137.152 kb on - strand at 5137.153 kb on + strand at 5137.153 kb on + strand at 5137.153 kb on + strand at 5137.154 kb on - strand at 5137.154 kb on - strand at 5137.154 kb on - strand at 5137.154 kb on - strand at 5137.154 kb on - strand at 5137.154 kb on - strand at 5137.154 kb on - strand at 5137.214 kb on - strand at 5137.214 kb on - strand at 5137.214 kb on - strand at 5137.248 kb on + strand at 5137.269 kb on + strand at 5137.269 kb on + strand at 5137.269 kb on + strand at 5137.269 kb on + strand at 5137.270 kb on - strand at 5137.270 kb on - strand at 5137.270 kb on - strand at 5137.270 kb on - strand at 5137.270 kb on - strand at 5137.270 kb on - strand at 5137.273 kb on + strand at 5137.273 kb on + strand at 5137.273 kb on + strand at 5137.273 kb on + strand at 5137.273 kb on + strand at 5137.273 kb on + strand at 5137.273 kb on + strand at 5137.273 kb on + strand at 5137.273 kb on + strand at 5137.273 kb on + strand at 5137.273 kb on + strand at 5137.273 kb on + strand at 5137.273 kb on + strand at 5137.273 kb on + strand at 5137.273 kb on + strand at 5137.273 kb on + strand at 5137.274 kb on - strand at 5137.274 kb on - strand at 5137.274 kb on - strand at 5137.274 kb on - strand at 5137.274 kb on - strand at 5137.274 kb on - strand at 5137.274 kb on - strand at 5137.274 kb on - strand at 5137.274 kb on - strand at 5137.274 kb on - strand at 5137.274 kb on - strand at 5137.274 kb on - strand at 5137.274 kb on - strand at 5137.274 kb on - strand at 5137.274 kb on - strand at 5137.274 kb on - strand at 5137.274 kb on - strand at 5137.274 kb on - strand at 5137.274 kb on - strand at 5137.311 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.25 mg/ml remove 5,134,163 + PfGW456L13_4599 0.74 -0.0 5,134,163 + PfGW456L13_4599 0.74 -2.0 5,134,163 + PfGW456L13_4599 0.74 -1.3 5,134,164 - PfGW456L13_4599 0.74 +0.4 5,134,164 - PfGW456L13_4599 0.74 -0.7 5,134,164 - PfGW456L13_4599 0.74 -2.6 5,134,299 - PfGW456L13_4599 0.78 +0.3 5,134,299 - PfGW456L13_4599 0.78 -2.4 5,134,307 - PfGW456L13_4599 0.79 -1.2 5,134,469 + PfGW456L13_4599 0.84 +0.7 5,134,469 + PfGW456L13_4599 0.84 -0.6 5,134,469 + PfGW456L13_4599 0.84 -0.7 5,134,469 + PfGW456L13_4599 0.84 -1.1 5,134,469 + PfGW456L13_4599 0.84 -0.5 5,134,470 - PfGW456L13_4599 0.84 -0.3 5,134,470 - PfGW456L13_4599 0.84 -3.2 5,134,515 - PfGW456L13_4599 0.86 -1.6 5,134,910 + -1.0 5,134,930 + +0.2 5,134,971 - +0.4 5,134,984 + -1.3 5,134,985 - +0.7 5,135,043 + +0.6 5,135,043 - +0.7 5,135,044 - +0.4 5,135,044 - -0.0 5,135,051 - +1.0 5,135,051 - +1.2 5,135,051 - -0.1 5,135,219 + PfGW456L13_4600 0.10 +0.3 5,135,219 + PfGW456L13_4600 0.10 -1.3 5,135,219 + PfGW456L13_4600 0.10 +0.3 5,135,219 + PfGW456L13_4600 0.10 -2.6 5,135,220 - PfGW456L13_4600 0.10 -0.0 5,135,220 - PfGW456L13_4600 0.10 +0.3 5,135,220 - PfGW456L13_4600 0.10 +1.4 5,135,220 - PfGW456L13_4600 0.10 -0.2 5,135,248 - PfGW456L13_4600 0.12 -1.0 5,135,354 + PfGW456L13_4600 0.20 -0.9 5,135,354 + PfGW456L13_4600 0.20 -0.2 5,135,355 - PfGW456L13_4600 0.20 -2.0 5,135,426 + PfGW456L13_4600 0.25 +0.2 5,135,436 + PfGW456L13_4600 0.26 -0.1 5,135,437 - PfGW456L13_4600 0.26 +0.5 5,135,437 - PfGW456L13_4600 0.26 -0.4 5,135,438 + PfGW456L13_4600 0.26 -0.4 5,135,438 + -1.3 5,135,438 + PfGW456L13_4600 0.26 -0.4 5,135,439 - PfGW456L13_4600 0.26 +0.8 5,135,439 - PfGW456L13_4600 0.26 +0.5 5,135,439 - PfGW456L13_4600 0.26 +0.2 5,135,447 + PfGW456L13_4600 0.27 +2.0 5,135,447 + PfGW456L13_4600 0.27 -0.0 5,135,448 - PfGW456L13_4600 0.27 +0.6 5,135,467 - PfGW456L13_4600 0.28 -0.1 5,135,474 - PfGW456L13_4600 0.29 -0.7 5,135,474 - PfGW456L13_4600 0.29 +0.4 5,135,653 - PfGW456L13_4600 0.42 +0.3 5,135,696 + PfGW456L13_4600 0.45 -2.4 5,135,696 + PfGW456L13_4600 0.45 -0.4 5,135,696 + PfGW456L13_4600 0.45 +0.9 5,135,696 + PfGW456L13_4600 0.45 -0.0 5,135,696 + PfGW456L13_4600 0.45 +0.1 5,135,696 + PfGW456L13_4600 0.45 +0.6 5,135,696 + PfGW456L13_4600 0.45 -2.2 5,135,697 - PfGW456L13_4600 0.45 -0.1 5,135,697 - PfGW456L13_4600 0.45 -0.6 5,135,697 - PfGW456L13_4600 0.45 +0.3 5,135,697 - PfGW456L13_4600 0.45 -0.1 5,135,735 + PfGW456L13_4600 0.48 -1.1 5,135,735 + PfGW456L13_4600 0.48 +0.6 5,135,735 + PfGW456L13_4600 0.48 -1.0 5,135,735 + PfGW456L13_4600 0.48 +0.1 5,135,735 + PfGW456L13_4600 0.48 -2.5 5,135,735 + PfGW456L13_4600 0.48 +0.8 5,135,735 + PfGW456L13_4600 0.48 -0.0 5,135,735 + PfGW456L13_4600 0.48 +3.8 5,135,735 + PfGW456L13_4600 0.48 -0.7 5,135,735 + PfGW456L13_4600 0.48 +0.5 5,135,735 + PfGW456L13_4600 0.48 -0.2 5,135,735 + PfGW456L13_4600 0.48 -0.2 5,135,735 + PfGW456L13_4600 0.48 +0.7 5,135,735 + PfGW456L13_4600 0.48 +0.5 5,135,735 + PfGW456L13_4600 0.48 -0.1 5,135,735 + PfGW456L13_4600 0.48 +2.2 5,135,735 + PfGW456L13_4600 0.48 +0.4 5,135,735 + PfGW456L13_4600 0.48 +0.2 5,135,735 + PfGW456L13_4600 0.48 -0.3 5,135,735 + PfGW456L13_4600 0.48 +0.3 5,135,736 - PfGW456L13_4600 0.48 +1.6 5,135,736 - PfGW456L13_4600 0.48 +0.8 5,135,736 - PfGW456L13_4600 0.48 +0.0 5,135,736 - PfGW456L13_4600 0.48 +0.1 5,135,736 - PfGW456L13_4600 0.48 -0.2 5,135,736 - PfGW456L13_4600 0.48 +0.2 5,135,736 - PfGW456L13_4600 0.48 -0.3 5,135,736 - PfGW456L13_4600 0.48 +0.7 5,135,736 - PfGW456L13_4600 0.48 +2.0 5,135,736 - PfGW456L13_4600 0.48 -1.2 5,135,736 - PfGW456L13_4600 0.48 -0.2 5,135,736 - PfGW456L13_4600 0.48 +1.1 5,135,736 - PfGW456L13_4600 0.48 +0.8 5,135,736 - PfGW456L13_4600 0.48 -1.2 5,135,736 - PfGW456L13_4600 0.48 -0.2 5,135,736 - PfGW456L13_4600 0.48 +0.7 5,135,736 - PfGW456L13_4600 0.48 +1.1 5,135,736 - PfGW456L13_4600 0.48 +0.8 5,135,736 - PfGW456L13_4600 0.48 -0.5 5,135,941 - PfGW456L13_4600 0.64 -0.0 5,136,255 - PfGW456L13_4600 0.87 +1.0 5,136,447 + +0.8 5,136,447 + -0.6 5,136,487 + -0.0 5,136,487 + -0.3 5,136,487 + +0.6 5,136,606 + -0.1 5,136,644 + -0.6 5,136,645 - -0.0 5,136,650 - -0.0 5,136,688 + +0.3 5,136,688 + -0.5 5,136,688 + +0.8 5,136,688 + -0.3 5,136,688 + -0.2 5,136,688 + +0.7 5,136,689 - +0.3 5,136,689 - +0.8 5,136,692 + +0.2 5,136,692 + +2.0 5,136,692 + +0.1 5,136,692 + -2.2 5,136,692 + -1.7 5,136,693 - +0.1 5,136,901 + -0.3 5,136,902 - +1.0 5,136,921 - PfGW456L13_4601 0.16 -2.5 5,137,071 + +0.8 5,137,071 + -0.8 5,137,072 - +0.6 5,137,072 - -0.5 5,137,087 + -0.4 5,137,092 + -0.7 5,137,093 - -0.6 5,137,093 - -0.9 5,137,095 + +2.0 5,137,096 - +0.4 5,137,096 - +0.9 5,137,151 + -1.5 5,137,151 + +1.1 5,137,151 + -0.3 5,137,151 + +1.1 5,137,152 - -0.8 5,137,152 - +1.0 5,137,152 - +0.3 5,137,152 - -0.9 5,137,152 - +1.0 5,137,152 - -2.6 5,137,152 - +0.8 5,137,152 - +0.9 5,137,152 - -0.2 5,137,153 + +0.1 5,137,153 + -0.3 5,137,153 + -0.2 5,137,154 - +0.4 5,137,154 - -0.6 5,137,154 - +0.2 5,137,154 - +0.6 5,137,154 - -0.8 5,137,154 - -0.0 5,137,154 - +0.7 5,137,214 - -0.1 5,137,214 - -0.5 5,137,214 - +1.1 5,137,248 + -0.6 5,137,269 + +0.2 5,137,269 + +0.1 5,137,269 + +0.2 5,137,269 + +0.6 5,137,270 - +0.3 5,137,270 - -0.5 5,137,270 - -1.0 5,137,270 - +0.3 5,137,270 - +1.6 5,137,270 - +1.0 5,137,273 + -0.1 5,137,273 + -0.7 5,137,273 + +0.2 5,137,273 + -1.0 5,137,273 + -1.3 5,137,273 + -0.8 5,137,273 + +0.2 5,137,273 + -0.8 5,137,273 + -1.2 5,137,273 + -1.5 5,137,273 + +1.2 5,137,273 + +0.3 5,137,273 + -0.1 5,137,273 + +0.2 5,137,273 + -0.1 5,137,273 + -0.4 5,137,274 - +1.6 5,137,274 - +0.5 5,137,274 - +0.2 5,137,274 - +0.7 5,137,274 - +0.1 5,137,274 - +0.3 5,137,274 - -0.0 5,137,274 - +0.2 5,137,274 - -0.0 5,137,274 - -1.3 5,137,274 - -0.1 5,137,274 - +0.4 5,137,274 - +0.5 5,137,274 - +0.4 5,137,274 - -0.8 5,137,274 - +1.1 5,137,274 - +0.0 5,137,274 - +0.6 5,137,274 - +0.1 5,137,311 - -1.0
Or see this region's nucleotide sequence