Experiment: Vancomycin 0.25 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_34 and PfGW456L13_35 are separated by 108 nucleotides PfGW456L13_35 and PfGW456L13_36 are separated by 55 nucleotides PfGW456L13_36 and PfGW456L13_37 are separated by 12 nucleotides
PfGW456L13_34 - Sensory box histidine kinase, at 39,849 to 42,536
_34
PfGW456L13_35 - Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1), at 42,645 to 43,208
_35
PfGW456L13_36 - lipoprotein, putative, at 43,264 to 43,872
_36
PfGW456L13_37 - 3-demethylubiquinone-9 3-methyltransferase (EC 2.1.1.64), at 43,885 to 44,634
_37
Position (kb) 42
43
44 Strain fitness (log2 ratio) -2
-1
0
1
2
3 at 41.662 kb on + strand, within PfGW456L13_34 at 41.662 kb on + strand, within PfGW456L13_34 at 41.662 kb on + strand, within PfGW456L13_34 at 41.662 kb on + strand, within PfGW456L13_34 at 41.662 kb on + strand, within PfGW456L13_34 at 41.662 kb on + strand, within PfGW456L13_34 at 41.663 kb on - strand, within PfGW456L13_34 at 41.663 kb on - strand, within PfGW456L13_34 at 41.663 kb on - strand, within PfGW456L13_34 at 41.663 kb on - strand at 41.663 kb on - strand, within PfGW456L13_34 at 41.896 kb on + strand, within PfGW456L13_34 at 41.896 kb on + strand, within PfGW456L13_34 at 41.897 kb on - strand, within PfGW456L13_34 at 41.897 kb on - strand, within PfGW456L13_34 at 41.923 kb on + strand, within PfGW456L13_34 at 41.923 kb on + strand, within PfGW456L13_34 at 41.923 kb on + strand, within PfGW456L13_34 at 41.923 kb on + strand, within PfGW456L13_34 at 41.924 kb on - strand, within PfGW456L13_34 at 41.924 kb on - strand, within PfGW456L13_34 at 41.924 kb on - strand, within PfGW456L13_34 at 41.935 kb on - strand, within PfGW456L13_34 at 42.095 kb on - strand, within PfGW456L13_34 at 42.149 kb on - strand, within PfGW456L13_34 at 42.178 kb on + strand, within PfGW456L13_34 at 42.178 kb on + strand, within PfGW456L13_34 at 42.178 kb on + strand, within PfGW456L13_34 at 42.178 kb on + strand, within PfGW456L13_34 at 42.179 kb on - strand, within PfGW456L13_34 at 42.179 kb on - strand, within PfGW456L13_34 at 42.179 kb on - strand, within PfGW456L13_34 at 42.179 kb on - strand, within PfGW456L13_34 at 42.179 kb on - strand, within PfGW456L13_34 at 42.179 kb on - strand, within PfGW456L13_34 at 42.179 kb on - strand, within PfGW456L13_34 at 42.264 kb on + strand, within PfGW456L13_34 at 42.264 kb on + strand, within PfGW456L13_34 at 42.279 kb on - strand at 42.411 kb on + strand at 42.411 kb on + strand at 42.411 kb on + strand at 42.411 kb on + strand at 42.411 kb on + strand at 42.412 kb on - strand at 42.412 kb on - strand at 42.412 kb on - strand at 42.412 kb on - strand at 42.412 kb on - strand at 42.481 kb on + strand at 42.481 kb on + strand at 42.482 kb on - strand at 42.482 kb on - strand at 42.615 kb on - strand at 42.646 kb on + strand at 42.646 kb on + strand at 42.646 kb on + strand at 42.646 kb on + strand at 42.647 kb on - strand at 42.647 kb on - strand at 42.647 kb on - strand at 42.647 kb on - strand at 42.647 kb on - strand at 42.665 kb on - strand at 42.665 kb on - strand at 42.738 kb on + strand, within PfGW456L13_35 at 42.738 kb on + strand, within PfGW456L13_35 at 42.738 kb on + strand, within PfGW456L13_35 at 42.738 kb on + strand, within PfGW456L13_35 at 42.738 kb on + strand, within PfGW456L13_35 at 42.739 kb on - strand, within PfGW456L13_35 at 42.739 kb on - strand, within PfGW456L13_35 at 42.739 kb on - strand, within PfGW456L13_35 at 42.739 kb on - strand, within PfGW456L13_35 at 42.818 kb on - strand, within PfGW456L13_35 at 42.818 kb on - strand, within PfGW456L13_35 at 42.841 kb on + strand, within PfGW456L13_35 at 42.841 kb on + strand, within PfGW456L13_35 at 42.841 kb on + strand, within PfGW456L13_35 at 42.841 kb on + strand, within PfGW456L13_35 at 42.841 kb on + strand, within PfGW456L13_35 at 42.841 kb on + strand, within PfGW456L13_35 at 42.841 kb on + strand, within PfGW456L13_35 at 42.841 kb on + strand, within PfGW456L13_35 at 42.841 kb on + strand, within PfGW456L13_35 at 42.841 kb on + strand, within PfGW456L13_35 at 42.842 kb on - strand, within PfGW456L13_35 at 42.842 kb on - strand, within PfGW456L13_35 at 42.842 kb on - strand, within PfGW456L13_35 at 42.842 kb on - strand, within PfGW456L13_35 at 42.842 kb on - strand, within PfGW456L13_35 at 42.842 kb on - strand, within PfGW456L13_35 at 42.842 kb on - strand, within PfGW456L13_35 at 42.842 kb on - strand, within PfGW456L13_35 at 42.842 kb on - strand, within PfGW456L13_35 at 42.842 kb on - strand, within PfGW456L13_35 at 42.842 kb on - strand, within PfGW456L13_35 at 42.842 kb on - strand, within PfGW456L13_35 at 42.845 kb on + strand, within PfGW456L13_35 at 42.845 kb on + strand, within PfGW456L13_35 at 42.845 kb on + strand, within PfGW456L13_35 at 42.845 kb on + strand, within PfGW456L13_35 at 42.845 kb on + strand, within PfGW456L13_35 at 42.845 kb on + strand, within PfGW456L13_35 at 42.846 kb on - strand, within PfGW456L13_35 at 42.846 kb on - strand, within PfGW456L13_35 at 42.846 kb on - strand, within PfGW456L13_35 at 42.856 kb on + strand, within PfGW456L13_35 at 42.860 kb on - strand, within PfGW456L13_35 at 42.860 kb on - strand, within PfGW456L13_35 at 42.860 kb on - strand, within PfGW456L13_35 at 42.866 kb on - strand, within PfGW456L13_35 at 42.892 kb on + strand, within PfGW456L13_35 at 42.892 kb on + strand, within PfGW456L13_35 at 42.892 kb on + strand, within PfGW456L13_35 at 42.893 kb on - strand, within PfGW456L13_35 at 42.893 kb on - strand, within PfGW456L13_35 at 42.893 kb on - strand, within PfGW456L13_35 at 42.934 kb on + strand, within PfGW456L13_35 at 42.935 kb on - strand, within PfGW456L13_35 at 42.935 kb on - strand, within PfGW456L13_35 at 42.935 kb on - strand, within PfGW456L13_35 at 43.069 kb on + strand, within PfGW456L13_35 at 43.106 kb on - strand, within PfGW456L13_35 at 43.189 kb on - strand at 43.251 kb on + strand at 43.252 kb on - strand at 43.252 kb on - strand at 43.252 kb on - strand at 43.252 kb on - strand at 43.256 kb on - strand at 43.265 kb on + strand at 43.265 kb on + strand at 43.266 kb on - strand at 43.269 kb on + strand at 43.269 kb on + strand at 43.269 kb on + strand at 43.269 kb on + strand at 43.269 kb on + strand at 43.269 kb on + strand at 43.269 kb on + strand at 43.269 kb on + strand at 43.270 kb on - strand at 43.270 kb on - strand at 43.270 kb on - strand at 43.270 kb on - strand at 43.278 kb on - strand at 43.398 kb on + strand, within PfGW456L13_36 at 43.398 kb on + strand, within PfGW456L13_36 at 43.398 kb on + strand, within PfGW456L13_36 at 43.398 kb on + strand, within PfGW456L13_36 at 43.399 kb on - strand, within PfGW456L13_36 at 43.399 kb on - strand, within PfGW456L13_36 at 43.399 kb on - strand, within PfGW456L13_36 at 43.399 kb on - strand, within PfGW456L13_36 at 43.430 kb on + strand, within PfGW456L13_36 at 43.430 kb on + strand, within PfGW456L13_36 at 43.430 kb on + strand, within PfGW456L13_36 at 43.430 kb on + strand, within PfGW456L13_36 at 43.430 kb on + strand, within PfGW456L13_36 at 43.431 kb on - strand, within PfGW456L13_36 at 43.434 kb on + strand, within PfGW456L13_36 at 43.435 kb on - strand, within PfGW456L13_36 at 43.435 kb on - strand, within PfGW456L13_36 at 43.435 kb on - strand, within PfGW456L13_36 at 43.447 kb on + strand, within PfGW456L13_36 at 43.447 kb on + strand, within PfGW456L13_36 at 43.447 kb on + strand, within PfGW456L13_36 at 43.478 kb on + strand, within PfGW456L13_36 at 43.488 kb on - strand, within PfGW456L13_36 at 43.488 kb on - strand, within PfGW456L13_36 at 43.488 kb on - strand, within PfGW456L13_36 at 43.511 kb on + strand, within PfGW456L13_36 at 43.511 kb on + strand, within PfGW456L13_36 at 43.512 kb on - strand, within PfGW456L13_36 at 43.522 kb on + strand, within PfGW456L13_36 at 43.715 kb on + strand, within PfGW456L13_36 at 43.805 kb on + strand, within PfGW456L13_36 at 43.806 kb on - strand, within PfGW456L13_36 at 43.806 kb on - strand, within PfGW456L13_36 at 43.806 kb on - strand, within PfGW456L13_36 at 43.853 kb on - strand at 43.853 kb on - strand at 43.913 kb on + strand at 44.012 kb on + strand, within PfGW456L13_37 at 44.012 kb on + strand, within PfGW456L13_37 at 44.012 kb on + strand, within PfGW456L13_37 at 44.012 kb on + strand, within PfGW456L13_37 at 44.012 kb on + strand, within PfGW456L13_37 at 44.012 kb on + strand, within PfGW456L13_37 at 44.012 kb on + strand, within PfGW456L13_37 at 44.012 kb on + strand, within PfGW456L13_37 at 44.012 kb on + strand, within PfGW456L13_37 at 44.012 kb on + strand, within PfGW456L13_37 at 44.012 kb on + strand, within PfGW456L13_37 at 44.013 kb on - strand, within PfGW456L13_37 at 44.013 kb on - strand, within PfGW456L13_37 at 44.013 kb on - strand, within PfGW456L13_37 at 44.013 kb on - strand, within PfGW456L13_37 at 44.013 kb on - strand, within PfGW456L13_37 at 44.180 kb on + strand, within PfGW456L13_37 at 44.180 kb on + strand, within PfGW456L13_37 at 44.180 kb on + strand, within PfGW456L13_37 at 44.181 kb on - strand, within PfGW456L13_37 at 44.181 kb on - strand, within PfGW456L13_37 at 44.181 kb on - strand, within PfGW456L13_37 at 44.182 kb on + strand, within PfGW456L13_37 at 44.182 kb on + strand, within PfGW456L13_37 at 44.182 kb on + strand, within PfGW456L13_37 at 44.183 kb on - strand, within PfGW456L13_37 at 44.183 kb on - strand, within PfGW456L13_37 at 44.183 kb on - strand, within PfGW456L13_37 at 44.183 kb on - strand, within PfGW456L13_37 at 44.183 kb on - strand, within PfGW456L13_37 at 44.183 kb on - strand, within PfGW456L13_37 at 44.201 kb on + strand, within PfGW456L13_37 at 44.202 kb on - strand, within PfGW456L13_37 at 44.202 kb on - strand, within PfGW456L13_37 at 44.202 kb on - strand, within PfGW456L13_37
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.25 mg/ml remove 41,662 + PfGW456L13_34 0.67 +0.9 41,662 + PfGW456L13_34 0.67 +1.2 41,662 + PfGW456L13_34 0.67 +0.1 41,662 + PfGW456L13_34 0.67 +1.0 41,662 + PfGW456L13_34 0.67 -1.1 41,662 + PfGW456L13_34 0.67 -0.4 41,663 - PfGW456L13_34 0.67 -1.0 41,663 - PfGW456L13_34 0.67 -0.1 41,663 - PfGW456L13_34 0.67 -0.0 41,663 - -0.4 41,663 - PfGW456L13_34 0.67 -1.5 41,896 + PfGW456L13_34 0.76 -0.1 41,896 + PfGW456L13_34 0.76 +0.3 41,897 - PfGW456L13_34 0.76 +1.2 41,897 - PfGW456L13_34 0.76 +0.4 41,923 + PfGW456L13_34 0.77 -1.2 41,923 + PfGW456L13_34 0.77 +0.6 41,923 + PfGW456L13_34 0.77 -0.3 41,923 + PfGW456L13_34 0.77 +0.4 41,924 - PfGW456L13_34 0.77 +0.4 41,924 - PfGW456L13_34 0.77 +0.7 41,924 - PfGW456L13_34 0.77 -0.1 41,935 - PfGW456L13_34 0.78 -0.6 42,095 - PfGW456L13_34 0.84 -0.6 42,149 - PfGW456L13_34 0.86 +0.9 42,178 + PfGW456L13_34 0.87 -0.3 42,178 + PfGW456L13_34 0.87 -0.3 42,178 + PfGW456L13_34 0.87 +0.5 42,178 + PfGW456L13_34 0.87 +0.4 42,179 - PfGW456L13_34 0.87 +0.2 42,179 - PfGW456L13_34 0.87 +0.5 42,179 - PfGW456L13_34 0.87 +2.3 42,179 - PfGW456L13_34 0.87 +0.0 42,179 - PfGW456L13_34 0.87 -0.4 42,179 - PfGW456L13_34 0.87 +0.5 42,179 - PfGW456L13_34 0.87 -0.7 42,264 + PfGW456L13_34 0.90 +0.3 42,264 + PfGW456L13_34 0.90 -0.2 42,279 - -0.3 42,411 + -0.4 42,411 + -0.4 42,411 + +0.0 42,411 + -0.8 42,411 + -0.7 42,412 - +0.7 42,412 - -0.1 42,412 - +1.0 42,412 - -0.7 42,412 - -0.3 42,481 + -0.6 42,481 + -0.2 42,482 - -0.7 42,482 - -0.3 42,615 - +0.1 42,646 + +0.2 42,646 + +0.4 42,646 + -1.2 42,646 + +0.4 42,647 - +0.3 42,647 - +0.0 42,647 - -0.0 42,647 - -0.5 42,647 - -0.5 42,665 - +0.0 42,665 - -0.3 42,738 + PfGW456L13_35 0.16 -0.2 42,738 + PfGW456L13_35 0.16 +0.6 42,738 + PfGW456L13_35 0.16 +1.0 42,738 + PfGW456L13_35 0.16 -0.9 42,738 + PfGW456L13_35 0.16 -1.2 42,739 - PfGW456L13_35 0.17 -0.2 42,739 - PfGW456L13_35 0.17 +1.2 42,739 - PfGW456L13_35 0.17 -0.0 42,739 - PfGW456L13_35 0.17 -1.2 42,818 - PfGW456L13_35 0.31 -0.6 42,818 - PfGW456L13_35 0.31 +0.7 42,841 + PfGW456L13_35 0.35 -0.2 42,841 + PfGW456L13_35 0.35 +0.5 42,841 + PfGW456L13_35 0.35 -0.4 42,841 + PfGW456L13_35 0.35 -0.7 42,841 + PfGW456L13_35 0.35 -0.1 42,841 + PfGW456L13_35 0.35 -0.5 42,841 + PfGW456L13_35 0.35 -0.0 42,841 + PfGW456L13_35 0.35 +0.5 42,841 + PfGW456L13_35 0.35 -0.4 42,841 + PfGW456L13_35 0.35 +0.5 42,842 - PfGW456L13_35 0.35 -0.4 42,842 - PfGW456L13_35 0.35 +0.7 42,842 - PfGW456L13_35 0.35 -0.1 42,842 - PfGW456L13_35 0.35 -0.2 42,842 - PfGW456L13_35 0.35 +0.9 42,842 - PfGW456L13_35 0.35 -1.3 42,842 - PfGW456L13_35 0.35 -1.3 42,842 - PfGW456L13_35 0.35 +0.0 42,842 - PfGW456L13_35 0.35 -0.2 42,842 - PfGW456L13_35 0.35 +1.7 42,842 - PfGW456L13_35 0.35 -1.7 42,842 - PfGW456L13_35 0.35 -0.3 42,845 + PfGW456L13_35 0.35 -0.8 42,845 + PfGW456L13_35 0.35 -1.0 42,845 + PfGW456L13_35 0.35 -0.8 42,845 + PfGW456L13_35 0.35 +0.6 42,845 + PfGW456L13_35 0.35 -1.6 42,845 + PfGW456L13_35 0.35 -1.8 42,846 - PfGW456L13_35 0.36 +0.3 42,846 - PfGW456L13_35 0.36 +0.5 42,846 - PfGW456L13_35 0.36 +0.2 42,856 + PfGW456L13_35 0.37 +0.3 42,860 - PfGW456L13_35 0.38 +0.7 42,860 - PfGW456L13_35 0.38 -1.2 42,860 - PfGW456L13_35 0.38 -1.4 42,866 - PfGW456L13_35 0.39 +0.5 42,892 + PfGW456L13_35 0.44 -1.7 42,892 + PfGW456L13_35 0.44 -0.5 42,892 + PfGW456L13_35 0.44 +0.3 42,893 - PfGW456L13_35 0.44 -0.7 42,893 - PfGW456L13_35 0.44 -0.5 42,893 - PfGW456L13_35 0.44 +0.3 42,934 + PfGW456L13_35 0.51 -0.3 42,935 - PfGW456L13_35 0.51 -0.8 42,935 - PfGW456L13_35 0.51 -0.5 42,935 - PfGW456L13_35 0.51 -0.4 43,069 + PfGW456L13_35 0.75 -0.1 43,106 - PfGW456L13_35 0.82 -0.1 43,189 - -0.1 43,251 + -1.1 43,252 - +0.5 43,252 - +0.5 43,252 - -1.5 43,252 - +0.5 43,256 - -0.7 43,265 + -2.5 43,265 + -0.8 43,266 - -1.8 43,269 + -0.9 43,269 + -0.4 43,269 + -0.8 43,269 + +0.6 43,269 + +0.3 43,269 + -0.2 43,269 + -0.3 43,269 + -0.8 43,270 - -1.6 43,270 - +0.3 43,270 - +0.8 43,270 - -0.4 43,278 - +0.4 43,398 + PfGW456L13_36 0.22 +0.1 43,398 + PfGW456L13_36 0.22 +0.2 43,398 + PfGW456L13_36 0.22 -0.1 43,398 + PfGW456L13_36 0.22 -1.7 43,399 - PfGW456L13_36 0.22 -0.8 43,399 - PfGW456L13_36 0.22 -0.1 43,399 - PfGW456L13_36 0.22 -0.2 43,399 - PfGW456L13_36 0.22 +0.3 43,430 + PfGW456L13_36 0.27 -1.2 43,430 + PfGW456L13_36 0.27 +0.6 43,430 + PfGW456L13_36 0.27 -0.4 43,430 + PfGW456L13_36 0.27 +0.7 43,430 + PfGW456L13_36 0.27 +1.1 43,431 - PfGW456L13_36 0.27 -0.2 43,434 + PfGW456L13_36 0.28 -0.3 43,435 - PfGW456L13_36 0.28 -0.3 43,435 - PfGW456L13_36 0.28 -0.2 43,435 - PfGW456L13_36 0.28 -0.1 43,447 + PfGW456L13_36 0.30 +0.6 43,447 + PfGW456L13_36 0.30 -0.0 43,447 + PfGW456L13_36 0.30 +0.2 43,478 + PfGW456L13_36 0.35 +0.1 43,488 - PfGW456L13_36 0.37 -0.7 43,488 - PfGW456L13_36 0.37 +0.8 43,488 - PfGW456L13_36 0.37 -0.5 43,511 + PfGW456L13_36 0.41 +0.6 43,511 + PfGW456L13_36 0.41 -0.7 43,512 - PfGW456L13_36 0.41 +1.0 43,522 + PfGW456L13_36 0.42 +0.0 43,715 + PfGW456L13_36 0.74 +0.2 43,805 + PfGW456L13_36 0.89 +1.0 43,806 - PfGW456L13_36 0.89 +0.2 43,806 - PfGW456L13_36 0.89 +0.5 43,806 - PfGW456L13_36 0.89 +0.2 43,853 - +0.8 43,853 - -2.1 43,913 + +0.9 44,012 + PfGW456L13_37 0.17 +0.4 44,012 + PfGW456L13_37 0.17 +0.2 44,012 + PfGW456L13_37 0.17 +0.2 44,012 + PfGW456L13_37 0.17 +1.0 44,012 + PfGW456L13_37 0.17 +0.2 44,012 + PfGW456L13_37 0.17 +0.8 44,012 + PfGW456L13_37 0.17 -0.4 44,012 + PfGW456L13_37 0.17 +1.2 44,012 + PfGW456L13_37 0.17 -1.2 44,012 + PfGW456L13_37 0.17 -0.5 44,012 + PfGW456L13_37 0.17 +1.7 44,013 - PfGW456L13_37 0.17 -0.5 44,013 - PfGW456L13_37 0.17 +1.1 44,013 - PfGW456L13_37 0.17 +1.5 44,013 - PfGW456L13_37 0.17 -0.8 44,013 - PfGW456L13_37 0.17 +0.2 44,180 + PfGW456L13_37 0.39 -0.4 44,180 + PfGW456L13_37 0.39 +3.3 44,180 + PfGW456L13_37 0.39 -0.1 44,181 - PfGW456L13_37 0.39 +0.6 44,181 - PfGW456L13_37 0.39 -0.3 44,181 - PfGW456L13_37 0.39 -1.5 44,182 + PfGW456L13_37 0.40 -0.7 44,182 + PfGW456L13_37 0.40 -0.3 44,182 + PfGW456L13_37 0.40 +0.5 44,183 - PfGW456L13_37 0.40 +0.9 44,183 - PfGW456L13_37 0.40 +1.0 44,183 - PfGW456L13_37 0.40 -0.1 44,183 - PfGW456L13_37 0.40 -0.3 44,183 - PfGW456L13_37 0.40 -0.6 44,183 - PfGW456L13_37 0.40 +1.4 44,201 + PfGW456L13_37 0.42 +0.3 44,202 - PfGW456L13_37 0.42 -0.0 44,202 - PfGW456L13_37 0.42 -1.6 44,202 - PfGW456L13_37 0.42 -0.4
Or see this region's nucleotide sequence