Experiment: Vancomycin 0.25 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_272 and PfGW456L13_273 overlap by 21 nucleotides PfGW456L13_273 and PfGW456L13_274 are separated by 13 nucleotides PfGW456L13_274 and PfGW456L13_275 are separated by 10 nucleotides
PfGW456L13_272 - Glutamate synthase [NADPH] large chain (EC 1.4.1.13), at 316,406 to 320,851
_272
PfGW456L13_273 - hypothetical protein, at 320,831 to 321,187
_273
PfGW456L13_274 - DamX, an inner membrane protein involved in bile resistance, at 321,201 to 322,802
_274
PfGW456L13_275 - 3-dehydroquinate synthase (EC 4.2.3.4), at 322,813 to 323,913
_275
Position (kb)
321
322
323 Strain fitness (log2 ratio)
-5
-4
-3
-2
-1
0
1
2 at 320.247 kb on + strand, within PfGW456L13_272 at 320.248 kb on - strand, within PfGW456L13_272 at 320.287 kb on - strand, within PfGW456L13_272 at 320.319 kb on + strand, within PfGW456L13_272 at 320.319 kb on + strand, within PfGW456L13_272 at 320.319 kb on + strand, within PfGW456L13_272 at 320.319 kb on + strand, within PfGW456L13_272 at 320.319 kb on + strand, within PfGW456L13_272 at 320.319 kb on + strand, within PfGW456L13_272 at 320.319 kb on + strand, within PfGW456L13_272 at 320.319 kb on + strand, within PfGW456L13_272 at 320.319 kb on + strand, within PfGW456L13_272 at 320.320 kb on - strand, within PfGW456L13_272 at 320.320 kb on - strand, within PfGW456L13_272 at 320.320 kb on - strand, within PfGW456L13_272 at 320.320 kb on - strand, within PfGW456L13_272 at 320.320 kb on - strand, within PfGW456L13_272 at 320.320 kb on - strand, within PfGW456L13_272 at 320.320 kb on - strand, within PfGW456L13_272 at 320.320 kb on - strand, within PfGW456L13_272 at 320.320 kb on - strand, within PfGW456L13_272 at 320.320 kb on - strand, within PfGW456L13_272 at 320.598 kb on + strand at 320.598 kb on + strand at 320.598 kb on + strand at 320.599 kb on - strand at 320.599 kb on - strand at 320.599 kb on - strand at 320.708 kb on - strand at 320.764 kb on + strand at 320.765 kb on - strand at 320.786 kb on - strand at 320.786 kb on - strand at 320.812 kb on + strand at 320.812 kb on + strand at 320.812 kb on + strand at 320.813 kb on - strand at 320.813 kb on - strand at 320.813 kb on - strand at 320.813 kb on - strand at 320.813 kb on - strand at 320.836 kb on - strand at 320.929 kb on - strand, within PfGW456L13_273 at 320.964 kb on + strand, within PfGW456L13_273 at 320.964 kb on + strand, within PfGW456L13_273 at 320.964 kb on + strand, within PfGW456L13_273 at 320.964 kb on + strand, within PfGW456L13_273 at 320.964 kb on + strand, within PfGW456L13_273 at 320.965 kb on - strand, within PfGW456L13_273 at 320.965 kb on - strand, within PfGW456L13_273 at 320.965 kb on - strand, within PfGW456L13_273 at 320.965 kb on - strand, within PfGW456L13_273 at 321.097 kb on + strand, within PfGW456L13_273 at 321.097 kb on + strand at 321.097 kb on + strand, within PfGW456L13_273 at 321.257 kb on + strand at 321.258 kb on - strand at 321.329 kb on - strand at 321.329 kb on - strand at 321.340 kb on + strand at 321.340 kb on + strand at 321.340 kb on + strand at 321.340 kb on + strand at 321.340 kb on + strand at 321.340 kb on + strand at 321.340 kb on + strand at 321.341 kb on - strand at 321.341 kb on - strand at 321.341 kb on - strand at 321.373 kb on + strand, within PfGW456L13_274 at 321.374 kb on - strand, within PfGW456L13_274 at 321.374 kb on - strand, within PfGW456L13_274 at 321.451 kb on + strand, within PfGW456L13_274 at 321.451 kb on + strand, within PfGW456L13_274 at 321.451 kb on + strand, within PfGW456L13_274 at 321.451 kb on + strand, within PfGW456L13_274 at 321.451 kb on + strand, within PfGW456L13_274 at 321.451 kb on + strand, within PfGW456L13_274 at 321.451 kb on + strand, within PfGW456L13_274 at 321.451 kb on + strand, within PfGW456L13_274 at 321.451 kb on + strand, within PfGW456L13_274 at 321.451 kb on + strand, within PfGW456L13_274 at 321.451 kb on + strand, within PfGW456L13_274 at 321.451 kb on + strand, within PfGW456L13_274 at 321.452 kb on - strand, within PfGW456L13_274 at 321.452 kb on - strand, within PfGW456L13_274 at 321.452 kb on - strand, within PfGW456L13_274 at 321.452 kb on - strand, within PfGW456L13_274 at 321.452 kb on - strand, within PfGW456L13_274 at 321.452 kb on - strand, within PfGW456L13_274 at 321.475 kb on + strand, within PfGW456L13_274 at 321.475 kb on + strand, within PfGW456L13_274 at 321.475 kb on + strand, within PfGW456L13_274 at 321.476 kb on - strand, within PfGW456L13_274 at 321.476 kb on - strand, within PfGW456L13_274 at 321.595 kb on - strand, within PfGW456L13_274 at 321.978 kb on + strand, within PfGW456L13_274 at 322.028 kb on + strand, within PfGW456L13_274 at 322.028 kb on + strand, within PfGW456L13_274 at 322.028 kb on + strand, within PfGW456L13_274 at 322.028 kb on + strand, within PfGW456L13_274 at 322.146 kb on - strand, within PfGW456L13_274 at 322.213 kb on + strand, within PfGW456L13_274 at 322.420 kb on + strand, within PfGW456L13_274 at 322.421 kb on - strand, within PfGW456L13_274 at 322.421 kb on - strand, within PfGW456L13_274 at 322.421 kb on - strand, within PfGW456L13_274 at 322.421 kb on - strand, within PfGW456L13_274 at 322.518 kb on + strand, within PfGW456L13_274 at 322.518 kb on + strand, within PfGW456L13_274 at 322.518 kb on + strand, within PfGW456L13_274 at 322.566 kb on + strand, within PfGW456L13_274 at 322.661 kb on - strand at 322.762 kb on + strand at 322.763 kb on - strand at 322.796 kb on + strand at 322.796 kb on + strand at 322.796 kb on + strand at 322.796 kb on + strand at 322.796 kb on + strand at 322.796 kb on + strand at 322.797 kb on - strand at 322.797 kb on - strand at 322.797 kb on - strand at 322.797 kb on - strand at 322.797 kb on - strand at 322.797 kb on - strand at 322.797 kb on - strand at 322.811 kb on + strand at 322.811 kb on + strand at 322.811 kb on + strand at 322.812 kb on - strand at 322.812 kb on - strand at 322.812 kb on - strand at 322.812 kb on - strand at 322.812 kb on - strand at 322.812 kb on - strand at 322.812 kb on - strand at 322.814 kb on + strand at 322.822 kb on - strand at 322.822 kb on - strand at 322.842 kb on - strand at 322.842 kb on - strand at 322.965 kb on + strand, within PfGW456L13_275 at 322.965 kb on + strand, within PfGW456L13_275 at 322.965 kb on + strand, within PfGW456L13_275 at 323.144 kb on + strand, within PfGW456L13_275 at 323.270 kb on + strand, within PfGW456L13_275
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.25 mg/ml remove 320,247 + PfGW456L13_272 0.86 +1.9 320,248 - PfGW456L13_272 0.86 +1.5 320,287 - PfGW456L13_272 0.87 +1.8 320,319 + PfGW456L13_272 0.88 -0.1 320,319 + PfGW456L13_272 0.88 +1.7 320,319 + PfGW456L13_272 0.88 +2.6 320,319 + PfGW456L13_272 0.88 +1.6 320,319 + PfGW456L13_272 0.88 +1.5 320,319 + PfGW456L13_272 0.88 +0.1 320,319 + PfGW456L13_272 0.88 +1.5 320,319 + PfGW456L13_272 0.88 +0.9 320,319 + PfGW456L13_272 0.88 +0.3 320,320 - PfGW456L13_272 0.88 +0.6 320,320 - PfGW456L13_272 0.88 +1.2 320,320 - PfGW456L13_272 0.88 +1.2 320,320 - PfGW456L13_272 0.88 +1.0 320,320 - PfGW456L13_272 0.88 +1.1 320,320 - PfGW456L13_272 0.88 +0.2 320,320 - PfGW456L13_272 0.88 +0.6 320,320 - PfGW456L13_272 0.88 +1.4 320,320 - PfGW456L13_272 0.88 +1.3 320,320 - PfGW456L13_272 0.88 +1.3 320,598 + +1.3 320,598 + +0.8 320,598 + +1.0 320,599 - +1.1 320,599 - +1.1 320,599 - +0.2 320,708 - +1.9 320,764 + +0.4 320,765 - +1.4 320,786 - +1.4 320,786 - +0.6 320,812 + +0.9 320,812 + +0.6 320,812 + -0.2 320,813 - +0.4 320,813 - +1.1 320,813 - +0.3 320,813 - +0.2 320,813 - +0.2 320,836 - +0.4 320,929 - PfGW456L13_273 0.27 -1.1 320,964 + PfGW456L13_273 0.37 +0.2 320,964 + PfGW456L13_273 0.37 +1.2 320,964 + PfGW456L13_273 0.37 +0.7 320,964 + PfGW456L13_273 0.37 +0.8 320,964 + PfGW456L13_273 0.37 -0.0 320,965 - PfGW456L13_273 0.38 -0.2 320,965 - PfGW456L13_273 0.38 -0.0 320,965 - PfGW456L13_273 0.38 +0.0 320,965 - PfGW456L13_273 0.38 -1.8 321,097 + PfGW456L13_273 0.75 +0.9 321,097 + +1.6 321,097 + PfGW456L13_273 0.75 +0.3 321,257 + -0.9 321,258 - -1.1 321,329 - -1.0 321,329 - +0.2 321,340 + -2.3 321,340 + -2.5 321,340 + -2.2 321,340 + -2.8 321,340 + -1.9 321,340 + -3.0 321,340 + -1.6 321,341 - -0.4 321,341 - -1.1 321,341 - -2.7 321,373 + PfGW456L13_274 0.11 -3.8 321,374 - PfGW456L13_274 0.11 -2.9 321,374 - PfGW456L13_274 0.11 -2.8 321,451 + PfGW456L13_274 0.16 -0.4 321,451 + PfGW456L13_274 0.16 -0.3 321,451 + PfGW456L13_274 0.16 -1.5 321,451 + PfGW456L13_274 0.16 -2.1 321,451 + PfGW456L13_274 0.16 -0.2 321,451 + PfGW456L13_274 0.16 -3.5 321,451 + PfGW456L13_274 0.16 -0.4 321,451 + PfGW456L13_274 0.16 -2.0 321,451 + PfGW456L13_274 0.16 -1.7 321,451 + PfGW456L13_274 0.16 -2.5 321,451 + PfGW456L13_274 0.16 -1.9 321,451 + PfGW456L13_274 0.16 -2.3 321,452 - PfGW456L13_274 0.16 -1.0 321,452 - PfGW456L13_274 0.16 -0.6 321,452 - PfGW456L13_274 0.16 -1.3 321,452 - PfGW456L13_274 0.16 -2.4 321,452 - PfGW456L13_274 0.16 -2.7 321,452 - PfGW456L13_274 0.16 -1.8 321,475 + PfGW456L13_274 0.17 -2.3 321,475 + PfGW456L13_274 0.17 -1.6 321,475 + PfGW456L13_274 0.17 -2.5 321,476 - PfGW456L13_274 0.17 -1.0 321,476 - PfGW456L13_274 0.17 -2.3 321,595 - PfGW456L13_274 0.25 +0.3 321,978 + PfGW456L13_274 0.49 -2.0 322,028 + PfGW456L13_274 0.52 -2.9 322,028 + PfGW456L13_274 0.52 -1.9 322,028 + PfGW456L13_274 0.52 -2.0 322,028 + PfGW456L13_274 0.52 -2.6 322,146 - PfGW456L13_274 0.59 -1.9 322,213 + PfGW456L13_274 0.63 +0.2 322,420 + PfGW456L13_274 0.76 -2.1 322,421 - PfGW456L13_274 0.76 -3.0 322,421 - PfGW456L13_274 0.76 -0.6 322,421 - PfGW456L13_274 0.76 -0.3 322,421 - PfGW456L13_274 0.76 -1.8 322,518 + PfGW456L13_274 0.82 -4.8 322,518 + PfGW456L13_274 0.82 -2.3 322,518 + PfGW456L13_274 0.82 -1.1 322,566 + PfGW456L13_274 0.85 -2.3 322,661 - -1.5 322,762 + -1.5 322,763 - -0.9 322,796 + -2.7 322,796 + -1.4 322,796 + -1.4 322,796 + -2.4 322,796 + -1.4 322,796 + -3.0 322,797 - -2.1 322,797 - -0.9 322,797 - -1.0 322,797 - -1.8 322,797 - -1.7 322,797 - -2.6 322,797 - -1.0 322,811 + -1.0 322,811 + +0.0 322,811 + -2.1 322,812 - -1.9 322,812 - -1.6 322,812 - -0.8 322,812 - -0.6 322,812 - -3.0 322,812 - -0.4 322,812 - -1.0 322,814 + -0.9 322,822 - +1.6 322,822 - +0.5 322,842 - +0.7 322,842 - +2.2 322,965 + PfGW456L13_275 0.14 -1.8 322,965 + PfGW456L13_275 0.14 -1.4 322,965 + PfGW456L13_275 0.14 -1.1 323,144 + PfGW456L13_275 0.30 -0.4 323,270 + PfGW456L13_275 0.42 -1.4
Or see this region's nucleotide sequence