Experiment: Vancomycin 0.25 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_2126 and PfGW456L13_2127 are separated by 19 nucleotides PfGW456L13_2127 and PfGW456L13_2128 are separated by 48 nucleotides
PfGW456L13_2126 - 2-dehydro-3-deoxygalactonokinase (EC 2.7.1.58), at 2,330,528 to 2,331,520
_2126
PfGW456L13_2127 - 2-dehydro-3-deoxyphosphogalactonate aldolase (EC 4.1.2.21), at 2,331,540 to 2,332,160
_2127
PfGW456L13_2128 - Galactonate dehydratase (EC 4.2.1.6), at 2,332,209 to 2,333,357
_2128
Position (kb)
2331
2332
2333 Strain fitness (log2 ratio)
-2
-1
0
1
2
3
4 at 2330.571 kb on + strand at 2330.571 kb on + strand at 2330.571 kb on + strand at 2330.571 kb on + strand at 2330.571 kb on + strand at 2330.571 kb on + strand at 2330.571 kb on + strand at 2330.572 kb on - strand at 2330.572 kb on - strand at 2330.572 kb on - strand at 2330.572 kb on - strand at 2330.579 kb on + strand at 2330.579 kb on + strand at 2330.580 kb on - strand at 2330.801 kb on + strand, within PfGW456L13_2126 at 2330.836 kb on + strand, within PfGW456L13_2126 at 2330.836 kb on + strand, within PfGW456L13_2126 at 2330.836 kb on + strand, within PfGW456L13_2126 at 2330.947 kb on - strand, within PfGW456L13_2126 at 2331.275 kb on + strand, within PfGW456L13_2126 at 2331.275 kb on + strand, within PfGW456L13_2126 at 2331.275 kb on + strand, within PfGW456L13_2126 at 2331.275 kb on + strand, within PfGW456L13_2126 at 2331.275 kb on + strand, within PfGW456L13_2126 at 2331.275 kb on + strand, within PfGW456L13_2126 at 2331.276 kb on - strand, within PfGW456L13_2126 at 2331.276 kb on - strand, within PfGW456L13_2126 at 2331.276 kb on - strand, within PfGW456L13_2126 at 2331.631 kb on - strand, within PfGW456L13_2127 at 2331.690 kb on - strand at 2331.707 kb on + strand, within PfGW456L13_2127 at 2331.707 kb on + strand, within PfGW456L13_2127 at 2331.708 kb on - strand, within PfGW456L13_2127 at 2331.708 kb on - strand at 2331.708 kb on - strand, within PfGW456L13_2127 at 2331.708 kb on - strand, within PfGW456L13_2127 at 2331.852 kb on + strand, within PfGW456L13_2127 at 2331.852 kb on + strand, within PfGW456L13_2127 at 2331.852 kb on + strand, within PfGW456L13_2127 at 2331.852 kb on + strand, within PfGW456L13_2127 at 2331.852 kb on + strand, within PfGW456L13_2127 at 2331.852 kb on + strand, within PfGW456L13_2127 at 2331.976 kb on + strand, within PfGW456L13_2127 at 2332.103 kb on + strand at 2332.103 kb on + strand at 2332.131 kb on + strand at 2332.131 kb on + strand at 2332.131 kb on + strand at 2332.132 kb on - strand at 2332.132 kb on - strand at 2332.132 kb on - strand at 2332.158 kb on + strand at 2332.159 kb on - strand at 2332.191 kb on + strand at 2332.191 kb on + strand at 2332.191 kb on + strand at 2332.192 kb on - strand at 2332.192 kb on - strand at 2332.192 kb on - strand at 2332.192 kb on - strand at 2332.192 kb on - strand at 2332.192 kb on - strand at 2332.192 kb on - strand at 2332.192 kb on - strand at 2332.194 kb on + strand at 2332.194 kb on + strand at 2332.194 kb on + strand at 2332.194 kb on + strand at 2332.194 kb on + strand at 2332.194 kb on + strand at 2332.194 kb on + strand at 2332.195 kb on - strand at 2332.195 kb on - strand at 2332.195 kb on - strand at 2332.195 kb on - strand at 2332.195 kb on - strand at 2332.360 kb on - strand, within PfGW456L13_2128 at 2332.557 kb on + strand, within PfGW456L13_2128 at 2332.558 kb on - strand, within PfGW456L13_2128 at 2332.747 kb on + strand, within PfGW456L13_2128 at 2332.748 kb on - strand, within PfGW456L13_2128 at 2332.748 kb on - strand, within PfGW456L13_2128 at 2332.815 kb on + strand, within PfGW456L13_2128 at 2332.816 kb on - strand, within PfGW456L13_2128 at 2332.857 kb on + strand at 2332.857 kb on + strand, within PfGW456L13_2128 at 2332.857 kb on + strand, within PfGW456L13_2128 at 2332.858 kb on - strand, within PfGW456L13_2128 at 2332.959 kb on + strand, within PfGW456L13_2128 at 2332.959 kb on + strand, within PfGW456L13_2128 at 2332.959 kb on + strand, within PfGW456L13_2128 at 2332.959 kb on + strand, within PfGW456L13_2128 at 2332.960 kb on - strand, within PfGW456L13_2128 at 2333.041 kb on - strand, within PfGW456L13_2128 at 2333.118 kb on + strand, within PfGW456L13_2128 at 2333.118 kb on + strand, within PfGW456L13_2128 at 2333.118 kb on + strand, within PfGW456L13_2128 at 2333.118 kb on + strand, within PfGW456L13_2128 at 2333.119 kb on - strand, within PfGW456L13_2128 at 2333.119 kb on - strand, within PfGW456L13_2128 at 2333.120 kb on + strand, within PfGW456L13_2128 at 2333.157 kb on + strand, within PfGW456L13_2128 at 2333.157 kb on + strand, within PfGW456L13_2128 at 2333.157 kb on + strand, within PfGW456L13_2128 at 2333.157 kb on + strand, within PfGW456L13_2128 at 2333.157 kb on + strand, within PfGW456L13_2128 at 2333.157 kb on + strand, within PfGW456L13_2128 at 2333.158 kb on - strand, within PfGW456L13_2128
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.25 mg/ml remove 2,330,571 + -0.4 2,330,571 + -0.4 2,330,571 + +0.4 2,330,571 + -1.0 2,330,571 + -0.3 2,330,571 + -0.3 2,330,571 + +0.0 2,330,572 - -1.2 2,330,572 - +0.9 2,330,572 - -0.4 2,330,572 - -0.7 2,330,579 + -0.1 2,330,579 + +0.7 2,330,580 - -1.7 2,330,801 + PfGW456L13_2126 0.27 -0.2 2,330,836 + PfGW456L13_2126 0.31 +0.9 2,330,836 + PfGW456L13_2126 0.31 +0.9 2,330,836 + PfGW456L13_2126 0.31 +0.2 2,330,947 - PfGW456L13_2126 0.42 -0.2 2,331,275 + PfGW456L13_2126 0.75 +1.7 2,331,275 + PfGW456L13_2126 0.75 -0.8 2,331,275 + PfGW456L13_2126 0.75 +0.8 2,331,275 + PfGW456L13_2126 0.75 +0.3 2,331,275 + PfGW456L13_2126 0.75 +0.1 2,331,275 + PfGW456L13_2126 0.75 +0.1 2,331,276 - PfGW456L13_2126 0.75 -0.9 2,331,276 - PfGW456L13_2126 0.75 +0.1 2,331,276 - PfGW456L13_2126 0.75 +0.7 2,331,631 - PfGW456L13_2127 0.15 -0.4 2,331,690 - -1.9 2,331,707 + PfGW456L13_2127 0.27 -0.2 2,331,707 + PfGW456L13_2127 0.27 -1.4 2,331,708 - PfGW456L13_2127 0.27 +0.3 2,331,708 - +0.9 2,331,708 - PfGW456L13_2127 0.27 -0.6 2,331,708 - PfGW456L13_2127 0.27 -0.1 2,331,852 + PfGW456L13_2127 0.50 -1.0 2,331,852 + PfGW456L13_2127 0.50 -0.4 2,331,852 + PfGW456L13_2127 0.50 +0.2 2,331,852 + PfGW456L13_2127 0.50 -0.8 2,331,852 + PfGW456L13_2127 0.50 +0.1 2,331,852 + PfGW456L13_2127 0.50 -1.4 2,331,976 + PfGW456L13_2127 0.70 -0.1 2,332,103 + -0.8 2,332,103 + +1.0 2,332,131 + -0.1 2,332,131 + -0.6 2,332,131 + -0.3 2,332,132 - -0.3 2,332,132 - +0.1 2,332,132 - +1.1 2,332,158 + +0.3 2,332,159 - +0.1 2,332,191 + +0.0 2,332,191 + -1.6 2,332,191 + +1.3 2,332,192 - -1.0 2,332,192 - -1.2 2,332,192 - -0.6 2,332,192 - -0.5 2,332,192 - -0.2 2,332,192 - +0.4 2,332,192 - -0.7 2,332,192 - -1.3 2,332,194 + +0.7 2,332,194 + -2.1 2,332,194 + +1.1 2,332,194 + +1.9 2,332,194 + -0.6 2,332,194 + -0.7 2,332,194 + +0.9 2,332,195 - -0.2 2,332,195 - -0.6 2,332,195 - +1.5 2,332,195 - -0.4 2,332,195 - +1.3 2,332,360 - PfGW456L13_2128 0.13 +0.5 2,332,557 + PfGW456L13_2128 0.30 +0.0 2,332,558 - PfGW456L13_2128 0.30 +0.2 2,332,747 + PfGW456L13_2128 0.47 -0.9 2,332,748 - PfGW456L13_2128 0.47 +1.2 2,332,748 - PfGW456L13_2128 0.47 -1.1 2,332,815 + PfGW456L13_2128 0.53 +0.3 2,332,816 - PfGW456L13_2128 0.53 +0.9 2,332,857 + +0.2 2,332,857 + PfGW456L13_2128 0.56 -1.0 2,332,857 + PfGW456L13_2128 0.56 +0.6 2,332,858 - PfGW456L13_2128 0.56 -2.6 2,332,959 + PfGW456L13_2128 0.65 +0.9 2,332,959 + PfGW456L13_2128 0.65 -0.3 2,332,959 + PfGW456L13_2128 0.65 -0.4 2,332,959 + PfGW456L13_2128 0.65 +0.8 2,332,960 - PfGW456L13_2128 0.65 +0.9 2,333,041 - PfGW456L13_2128 0.72 -0.9 2,333,118 + PfGW456L13_2128 0.79 -0.1 2,333,118 + PfGW456L13_2128 0.79 +0.7 2,333,118 + PfGW456L13_2128 0.79 -0.4 2,333,118 + PfGW456L13_2128 0.79 +0.9 2,333,119 - PfGW456L13_2128 0.79 -0.4 2,333,119 - PfGW456L13_2128 0.79 -0.3 2,333,120 + PfGW456L13_2128 0.79 +0.6 2,333,157 + PfGW456L13_2128 0.83 +3.9 2,333,157 + PfGW456L13_2128 0.83 -1.8 2,333,157 + PfGW456L13_2128 0.83 -0.5 2,333,157 + PfGW456L13_2128 0.83 -0.7 2,333,157 + PfGW456L13_2128 0.83 -0.4 2,333,157 + PfGW456L13_2128 0.83 -1.8 2,333,158 - PfGW456L13_2128 0.83 -1.1
Or see this region's nucleotide sequence