Experiment: Vancomycin 0.25 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_1308 and PfGW456L13_1309 are separated by 18 nucleotides PfGW456L13_1309 and PfGW456L13_1310 are separated by 0 nucleotides PfGW456L13_1310 and PfGW456L13_1311 overlap by 4 nucleotides PfGW456L13_1311 and PfGW456L13_1312 are separated by 127 nucleotides PfGW456L13_1312 and PfGW456L13_1313 overlap by 4 nucleotides
PfGW456L13_1308 - FIG000875: Thioredoxin domain-containing protein EC-YbbN, at 1,450,601 to 1,451,473
_1308
PfGW456L13_1309 - hypothetical protein, at 1,451,492 to 1,451,656
_1309
PfGW456L13_1310 - Glutamate synthase [NADPH] large chain (EC 1.4.1.13), at 1,451,657 to 1,452,310
_1310
PfGW456L13_1311 - Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1), at 1,452,307 to 1,452,771
_1311
PfGW456L13_1312 - Ribonucleotide reductase transcriptional regulator NrdR, at 1,452,899 to 1,453,363
_1312
PfGW456L13_1313 - Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) / 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193), at 1,453,360 to 1,454,493
_1313
Position (kb)
1452
1453 Strain fitness (log2 ratio)
-3
-2
-1
0
1 at 1451.310 kb on + strand, within PfGW456L13_1308 at 1451.310 kb on + strand, within PfGW456L13_1308 at 1451.310 kb on + strand, within PfGW456L13_1308 at 1451.310 kb on + strand, within PfGW456L13_1308 at 1451.310 kb on + strand, within PfGW456L13_1308 at 1451.310 kb on + strand, within PfGW456L13_1308 at 1451.310 kb on + strand, within PfGW456L13_1308 at 1451.310 kb on + strand, within PfGW456L13_1308 at 1451.311 kb on - strand, within PfGW456L13_1308 at 1451.311 kb on - strand, within PfGW456L13_1308 at 1451.311 kb on - strand, within PfGW456L13_1308 at 1451.311 kb on - strand, within PfGW456L13_1308 at 1451.454 kb on + strand at 1451.454 kb on + strand at 1451.455 kb on - strand at 1451.455 kb on - strand at 1451.455 kb on - strand at 1451.455 kb on - strand at 1451.455 kb on - strand at 1451.455 kb on - strand at 1451.455 kb on - strand at 1451.485 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.506 kb on + strand at 1451.507 kb on - strand at 1451.507 kb on - strand at 1451.507 kb on - strand at 1451.507 kb on - strand at 1451.507 kb on - strand at 1451.507 kb on - strand at 1451.507 kb on - strand at 1451.507 kb on - strand at 1451.507 kb on - strand at 1451.507 kb on - strand at 1451.507 kb on - strand at 1451.507 kb on - strand at 1451.507 kb on - strand at 1451.508 kb on + strand at 1451.508 kb on + strand at 1451.508 kb on + strand at 1451.508 kb on + strand at 1451.508 kb on + strand at 1451.509 kb on - strand, within PfGW456L13_1309 at 1451.509 kb on - strand, within PfGW456L13_1309 at 1451.509 kb on - strand, within PfGW456L13_1309 at 1451.509 kb on - strand, within PfGW456L13_1309 at 1451.509 kb on - strand, within PfGW456L13_1309 at 1451.547 kb on + strand, within PfGW456L13_1309 at 1451.548 kb on - strand, within PfGW456L13_1309 at 1451.654 kb on + strand at 1451.654 kb on + strand at 1451.655 kb on - strand at 1451.655 kb on - strand at 1451.655 kb on - strand at 1451.655 kb on - strand at 1451.655 kb on - strand at 1451.655 kb on - strand at 1451.659 kb on - strand at 1451.673 kb on + strand at 1451.673 kb on + strand at 1451.674 kb on - strand at 1451.674 kb on - strand at 1451.752 kb on - strand, within PfGW456L13_1310 at 1451.850 kb on + strand, within PfGW456L13_1310 at 1451.850 kb on + strand, within PfGW456L13_1310 at 1451.850 kb on + strand, within PfGW456L13_1310 at 1451.851 kb on - strand, within PfGW456L13_1310 at 1451.851 kb on - strand, within PfGW456L13_1310 at 1451.851 kb on - strand, within PfGW456L13_1310 at 1451.851 kb on - strand, within PfGW456L13_1310 at 1451.855 kb on + strand, within PfGW456L13_1310 at 1451.855 kb on + strand, within PfGW456L13_1310 at 1451.855 kb on + strand, within PfGW456L13_1310 at 1451.855 kb on + strand, within PfGW456L13_1310 at 1451.856 kb on - strand, within PfGW456L13_1310 at 1451.856 kb on - strand, within PfGW456L13_1310 at 1451.856 kb on - strand, within PfGW456L13_1310 at 1451.856 kb on - strand, within PfGW456L13_1310 at 1451.856 kb on - strand, within PfGW456L13_1310 at 1451.856 kb on - strand, within PfGW456L13_1310 at 1451.856 kb on - strand, within PfGW456L13_1310 at 1451.913 kb on + strand, within PfGW456L13_1310 at 1451.914 kb on - strand, within PfGW456L13_1310 at 1451.914 kb on - strand, within PfGW456L13_1310 at 1451.924 kb on + strand, within PfGW456L13_1310 at 1451.924 kb on + strand, within PfGW456L13_1310 at 1451.924 kb on + strand, within PfGW456L13_1310 at 1451.924 kb on + strand, within PfGW456L13_1310 at 1451.925 kb on - strand, within PfGW456L13_1310 at 1451.925 kb on - strand, within PfGW456L13_1310 at 1451.925 kb on - strand, within PfGW456L13_1310 at 1451.925 kb on - strand, within PfGW456L13_1310 at 1451.925 kb on - strand, within PfGW456L13_1310 at 1451.925 kb on - strand, within PfGW456L13_1310 at 1451.925 kb on - strand, within PfGW456L13_1310 at 1451.990 kb on + strand, within PfGW456L13_1310 at 1451.991 kb on - strand, within PfGW456L13_1310 at 1451.991 kb on - strand, within PfGW456L13_1310 at 1452.139 kb on - strand, within PfGW456L13_1310 at 1452.237 kb on - strand, within PfGW456L13_1310 at 1452.360 kb on + strand, within PfGW456L13_1311 at 1452.534 kb on + strand, within PfGW456L13_1311 at 1452.763 kb on + strand at 1452.764 kb on - strand at 1452.783 kb on + strand at 1452.822 kb on + strand at 1452.822 kb on + strand at 1452.822 kb on + strand at 1452.822 kb on + strand at 1452.823 kb on - strand at 1452.823 kb on - strand at 1452.836 kb on + strand at 1452.837 kb on - strand at 1452.837 kb on - strand at 1452.864 kb on + strand at 1453.268 kb on + strand, within PfGW456L13_1312 at 1453.268 kb on + strand, within PfGW456L13_1312 at 1453.268 kb on + strand, within PfGW456L13_1312 at 1453.268 kb on + strand, within PfGW456L13_1312 at 1453.268 kb on + strand, within PfGW456L13_1312 at 1453.289 kb on + strand, within PfGW456L13_1312
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.25 mg/ml remove 1,451,310 + PfGW456L13_1308 0.81 -0.3 1,451,310 + PfGW456L13_1308 0.81 -0.7 1,451,310 + PfGW456L13_1308 0.81 -1.7 1,451,310 + PfGW456L13_1308 0.81 -1.8 1,451,310 + PfGW456L13_1308 0.81 -0.6 1,451,310 + PfGW456L13_1308 0.81 +1.5 1,451,310 + PfGW456L13_1308 0.81 +0.2 1,451,310 + PfGW456L13_1308 0.81 -0.5 1,451,311 - PfGW456L13_1308 0.81 +0.2 1,451,311 - PfGW456L13_1308 0.81 +0.6 1,451,311 - PfGW456L13_1308 0.81 -2.0 1,451,311 - PfGW456L13_1308 0.81 -0.4 1,451,454 + -0.7 1,451,454 + -0.4 1,451,455 - -1.2 1,451,455 - +1.3 1,451,455 - -1.5 1,451,455 - +0.5 1,451,455 - +0.1 1,451,455 - +0.7 1,451,455 - -0.6 1,451,485 + -0.0 1,451,506 + -2.9 1,451,506 + +0.8 1,451,506 + +0.1 1,451,506 + -0.2 1,451,506 + +0.0 1,451,506 + -1.6 1,451,506 + +0.6 1,451,506 + +0.7 1,451,506 + +0.3 1,451,506 + -1.2 1,451,506 + -0.4 1,451,506 + -0.9 1,451,506 + -0.1 1,451,506 + +1.5 1,451,506 + +0.8 1,451,506 + -3.6 1,451,506 + +0.1 1,451,506 + +1.1 1,451,506 + -0.6 1,451,506 + -1.1 1,451,506 + -0.3 1,451,506 + +0.6 1,451,506 + -0.4 1,451,506 + -0.2 1,451,506 + +1.2 1,451,506 + -0.8 1,451,506 + +0.4 1,451,507 - +0.6 1,451,507 - +0.2 1,451,507 - +0.1 1,451,507 - +0.9 1,451,507 - +0.2 1,451,507 - -0.4 1,451,507 - +0.1 1,451,507 - -0.4 1,451,507 - -0.4 1,451,507 - -1.0 1,451,507 - -0.7 1,451,507 - +1.2 1,451,507 - -1.2 1,451,508 + +0.1 1,451,508 + -0.0 1,451,508 + -0.1 1,451,508 + -1.9 1,451,508 + +0.7 1,451,509 - PfGW456L13_1309 0.10 +0.2 1,451,509 - PfGW456L13_1309 0.10 -0.1 1,451,509 - PfGW456L13_1309 0.10 +0.6 1,451,509 - PfGW456L13_1309 0.10 +0.6 1,451,509 - PfGW456L13_1309 0.10 +1.0 1,451,547 + PfGW456L13_1309 0.33 +0.4 1,451,548 - PfGW456L13_1309 0.34 -0.2 1,451,654 + +0.8 1,451,654 + +0.3 1,451,655 - -0.8 1,451,655 - +0.1 1,451,655 - +0.2 1,451,655 - -0.0 1,451,655 - -2.0 1,451,655 - -0.0 1,451,659 - +0.5 1,451,673 + -0.1 1,451,673 + -0.1 1,451,674 - -0.2 1,451,674 - +0.5 1,451,752 - PfGW456L13_1310 0.15 -0.1 1,451,850 + PfGW456L13_1310 0.30 +1.1 1,451,850 + PfGW456L13_1310 0.30 +0.2 1,451,850 + PfGW456L13_1310 0.30 -0.1 1,451,851 - PfGW456L13_1310 0.30 -0.9 1,451,851 - PfGW456L13_1310 0.30 -1.2 1,451,851 - PfGW456L13_1310 0.30 -0.6 1,451,851 - PfGW456L13_1310 0.30 +0.8 1,451,855 + PfGW456L13_1310 0.30 +0.1 1,451,855 + PfGW456L13_1310 0.30 +0.1 1,451,855 + PfGW456L13_1310 0.30 +0.1 1,451,855 + PfGW456L13_1310 0.30 +0.9 1,451,856 - PfGW456L13_1310 0.30 +0.0 1,451,856 - PfGW456L13_1310 0.30 -0.6 1,451,856 - PfGW456L13_1310 0.30 +1.0 1,451,856 - PfGW456L13_1310 0.30 +0.3 1,451,856 - PfGW456L13_1310 0.30 -0.2 1,451,856 - PfGW456L13_1310 0.30 -0.3 1,451,856 - PfGW456L13_1310 0.30 +0.2 1,451,913 + PfGW456L13_1310 0.39 -0.2 1,451,914 - PfGW456L13_1310 0.39 -0.3 1,451,914 - PfGW456L13_1310 0.39 +0.5 1,451,924 + PfGW456L13_1310 0.41 -2.0 1,451,924 + PfGW456L13_1310 0.41 +1.2 1,451,924 + PfGW456L13_1310 0.41 +1.0 1,451,924 + PfGW456L13_1310 0.41 -1.5 1,451,925 - PfGW456L13_1310 0.41 +0.1 1,451,925 - PfGW456L13_1310 0.41 -0.5 1,451,925 - PfGW456L13_1310 0.41 -0.0 1,451,925 - PfGW456L13_1310 0.41 -0.1 1,451,925 - PfGW456L13_1310 0.41 -1.0 1,451,925 - PfGW456L13_1310 0.41 -0.9 1,451,925 - PfGW456L13_1310 0.41 +0.2 1,451,990 + PfGW456L13_1310 0.51 -0.7 1,451,991 - PfGW456L13_1310 0.51 -0.3 1,451,991 - PfGW456L13_1310 0.51 +0.2 1,452,139 - PfGW456L13_1310 0.74 -0.0 1,452,237 - PfGW456L13_1310 0.89 +0.4 1,452,360 + PfGW456L13_1311 0.11 +0.3 1,452,534 + PfGW456L13_1311 0.49 +1.4 1,452,763 + -1.3 1,452,764 - +0.2 1,452,783 + +0.3 1,452,822 + -0.9 1,452,822 + +0.6 1,452,822 + -0.8 1,452,822 + -0.5 1,452,823 - +0.3 1,452,823 - +0.5 1,452,836 + +0.3 1,452,837 - +0.1 1,452,837 - -0.4 1,452,864 + +0.8 1,453,268 + PfGW456L13_1312 0.79 -1.1 1,453,268 + PfGW456L13_1312 0.79 +0.0 1,453,268 + PfGW456L13_1312 0.79 -0.1 1,453,268 + PfGW456L13_1312 0.79 -0.7 1,453,268 + PfGW456L13_1312 0.79 -0.8 1,453,289 + PfGW456L13_1312 0.84 -1.3
Or see this region's nucleotide sequence