Experiment: Vancomycin 0.125 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_843 and PfGW456L13_844 are separated by 13 nucleotides PfGW456L13_844 and PfGW456L13_845 are separated by 4 nucleotides PfGW456L13_845 and PfGW456L13_846 are separated by 12 nucleotides PfGW456L13_846 and PfGW456L13_847 overlap by 18 nucleotides PfGW456L13_847 and PfGW456L13_848 overlap by 1 nucleotides
PfGW456L13_843 - Protein of unknown function DUF484, at 950,686 to 951,411
_843
PfGW456L13_844 - Diaminopimelate epimerase (EC 5.1.1.7), at 951,425 to 952,255
_844
PfGW456L13_845 - Diaminopimelate decarboxylase (EC 4.1.1.20), at 952,260 to 953,507
_845
PfGW456L13_846 - Lipoprotein LppL-related protein, at 953,520 to 953,645
_846
PfGW456L13_847 - hypothetical protein, at 953,628 to 953,906
_847
PfGW456L13_848 - Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly, at 953,906 to 954,238
_848
Position (kb) 952
953
954 Strain fitness (log2 ratio) -4
-3
-2
-1
0
1
2 at 951.270 kb on + strand, within PfGW456L13_843 at 951.338 kb on - strand, within PfGW456L13_843 at 951.338 kb on - strand, within PfGW456L13_843 at 951.447 kb on + strand at 951.447 kb on + strand at 951.447 kb on + strand at 951.447 kb on + strand at 951.448 kb on - strand at 951.448 kb on - strand at 951.448 kb on - strand at 951.448 kb on - strand at 951.449 kb on + strand at 951.449 kb on + strand at 951.449 kb on + strand at 951.450 kb on - strand at 951.450 kb on - strand at 951.450 kb on - strand at 951.450 kb on - strand at 951.450 kb on - strand at 951.450 kb on - strand at 951.450 kb on - strand at 951.450 kb on - strand at 951.450 kb on - strand at 951.450 kb on - strand at 951.450 kb on - strand at 951.450 kb on - strand at 951.450 kb on - strand at 951.450 kb on - strand at 951.450 kb on - strand at 951.450 kb on - strand at 951.537 kb on - strand, within PfGW456L13_844 at 951.835 kb on - strand, within PfGW456L13_844 at 952.240 kb on + strand at 952.240 kb on + strand at 952.240 kb on + strand at 952.241 kb on - strand at 952.262 kb on - strand at 952.288 kb on + strand at 952.288 kb on + strand at 952.288 kb on + strand at 952.288 kb on + strand at 952.288 kb on + strand at 952.289 kb on - strand at 952.289 kb on - strand at 952.289 kb on - strand at 952.289 kb on - strand at 952.289 kb on - strand at 952.289 kb on - strand at 952.289 kb on - strand at 952.289 kb on - strand at 952.289 kb on - strand at 952.289 kb on - strand at 952.289 kb on - strand at 952.289 kb on - strand at 952.375 kb on + strand at 952.375 kb on + strand at 952.376 kb on - strand at 952.376 kb on - strand at 952.376 kb on - strand at 952.562 kb on - strand, within PfGW456L13_845 at 952.562 kb on - strand, within PfGW456L13_845 at 952.562 kb on - strand, within PfGW456L13_845 at 952.637 kb on - strand, within PfGW456L13_845 at 952.744 kb on + strand, within PfGW456L13_845 at 952.744 kb on + strand, within PfGW456L13_845 at 952.745 kb on - strand, within PfGW456L13_845 at 952.745 kb on - strand, within PfGW456L13_845 at 952.745 kb on - strand, within PfGW456L13_845 at 952.745 kb on - strand, within PfGW456L13_845 at 952.819 kb on + strand, within PfGW456L13_845 at 952.819 kb on + strand, within PfGW456L13_845 at 952.820 kb on - strand, within PfGW456L13_845 at 952.820 kb on - strand, within PfGW456L13_845 at 952.820 kb on - strand, within PfGW456L13_845 at 952.820 kb on - strand, within PfGW456L13_845 at 952.820 kb on - strand, within PfGW456L13_845 at 952.820 kb on - strand, within PfGW456L13_845 at 952.963 kb on + strand, within PfGW456L13_845 at 952.963 kb on + strand, within PfGW456L13_845 at 952.963 kb on + strand, within PfGW456L13_845 at 952.963 kb on + strand, within PfGW456L13_845 at 952.964 kb on - strand, within PfGW456L13_845 at 952.964 kb on - strand, within PfGW456L13_845 at 952.964 kb on - strand, within PfGW456L13_845 at 952.964 kb on - strand, within PfGW456L13_845 at 952.964 kb on - strand, within PfGW456L13_845 at 952.964 kb on - strand, within PfGW456L13_845 at 952.964 kb on - strand, within PfGW456L13_845 at 952.964 kb on - strand, within PfGW456L13_845 at 953.026 kb on + strand, within PfGW456L13_845 at 953.339 kb on - strand, within PfGW456L13_845 at 953.377 kb on + strand, within PfGW456L13_845 at 953.378 kb on - strand, within PfGW456L13_845 at 953.387 kb on - strand at 953.387 kb on - strand at 953.387 kb on - strand at 953.387 kb on - strand at 953.419 kb on + strand at 953.419 kb on + strand at 953.420 kb on - strand at 953.420 kb on - strand at 953.420 kb on - strand at 953.420 kb on - strand at 953.420 kb on - strand at 953.420 kb on - strand at 953.429 kb on + strand at 953.492 kb on - strand at 953.495 kb on + strand at 953.496 kb on - strand at 953.496 kb on - strand at 953.496 kb on - strand at 953.518 kb on + strand at 953.518 kb on + strand at 953.518 kb on + strand at 953.519 kb on - strand at 953.519 kb on - strand at 953.519 kb on - strand at 953.522 kb on - strand at 953.522 kb on - strand at 953.522 kb on - strand at 953.527 kb on + strand at 953.527 kb on + strand at 953.528 kb on - strand at 953.528 kb on - strand at 953.528 kb on - strand at 953.720 kb on - strand, within PfGW456L13_847 at 953.720 kb on - strand, within PfGW456L13_847 at 953.720 kb on - strand, within PfGW456L13_847 at 953.734 kb on - strand, within PfGW456L13_847 at 953.735 kb on + strand, within PfGW456L13_847 at 953.759 kb on - strand, within PfGW456L13_847 at 953.830 kb on - strand, within PfGW456L13_847 at 953.858 kb on + strand, within PfGW456L13_847 at 953.859 kb on - strand, within PfGW456L13_847 at 954.122 kb on + strand, within PfGW456L13_848 at 954.190 kb on + strand, within PfGW456L13_848 at 954.190 kb on + strand, within PfGW456L13_848 at 954.191 kb on - strand, within PfGW456L13_848 at 954.191 kb on - strand, within PfGW456L13_848 at 954.283 kb on - strand at 954.283 kb on - strand at 954.380 kb on + strand at 954.380 kb on + strand at 954.381 kb on - strand at 954.381 kb on - strand at 954.381 kb on - strand at 954.413 kb on + strand at 954.413 kb on + strand at 954.414 kb on - strand at 954.460 kb on - strand at 954.460 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.125 mg/ml remove 951,270 + PfGW456L13_843 0.80 -1.0 951,338 - PfGW456L13_843 0.90 -1.2 951,338 - PfGW456L13_843 0.90 -0.4 951,447 + +0.1 951,447 + -0.2 951,447 + -0.1 951,447 + -0.3 951,448 - -0.0 951,448 - +1.2 951,448 - -0.8 951,448 - -0.1 951,449 + -1.3 951,449 + +0.3 951,449 + -0.5 951,450 - +0.2 951,450 - +1.9 951,450 - +0.4 951,450 - -0.3 951,450 - +1.5 951,450 - +0.2 951,450 - +0.0 951,450 - +0.0 951,450 - -0.6 951,450 - -0.6 951,450 - +0.1 951,450 - +0.2 951,450 - +0.4 951,450 - -0.5 951,450 - -0.6 951,450 - -0.9 951,537 - PfGW456L13_844 0.13 +0.3 951,835 - PfGW456L13_844 0.49 +0.9 952,240 + -0.1 952,240 + +0.5 952,240 + +0.6 952,241 - -0.9 952,262 - -1.0 952,288 + -1.8 952,288 + -1.9 952,288 + -2.1 952,288 + -2.1 952,288 + -2.4 952,289 - -3.0 952,289 - -4.0 952,289 - -1.6 952,289 - -1.4 952,289 - -0.7 952,289 - -3.3 952,289 - -3.0 952,289 - -2.6 952,289 - -2.0 952,289 - -0.2 952,289 - -2.1 952,289 - -2.0 952,375 + -1.8 952,375 + -0.7 952,376 - -1.8 952,376 - -1.7 952,376 - -3.6 952,562 - PfGW456L13_845 0.24 -2.0 952,562 - PfGW456L13_845 0.24 -1.4 952,562 - PfGW456L13_845 0.24 -3.2 952,637 - PfGW456L13_845 0.30 -2.5 952,744 + PfGW456L13_845 0.39 -1.9 952,744 + PfGW456L13_845 0.39 -2.3 952,745 - PfGW456L13_845 0.39 -1.7 952,745 - PfGW456L13_845 0.39 -1.0 952,745 - PfGW456L13_845 0.39 -1.3 952,745 - PfGW456L13_845 0.39 -3.5 952,819 + PfGW456L13_845 0.45 -2.3 952,819 + PfGW456L13_845 0.45 -0.1 952,820 - PfGW456L13_845 0.45 -2.2 952,820 - PfGW456L13_845 0.45 +0.5 952,820 - PfGW456L13_845 0.45 -0.9 952,820 - PfGW456L13_845 0.45 -2.9 952,820 - PfGW456L13_845 0.45 -2.6 952,820 - PfGW456L13_845 0.45 -1.8 952,963 + PfGW456L13_845 0.56 -3.4 952,963 + PfGW456L13_845 0.56 -2.6 952,963 + PfGW456L13_845 0.56 -0.7 952,963 + PfGW456L13_845 0.56 -0.9 952,964 - PfGW456L13_845 0.56 -1.9 952,964 - PfGW456L13_845 0.56 -2.8 952,964 - PfGW456L13_845 0.56 -1.7 952,964 - PfGW456L13_845 0.56 -1.0 952,964 - PfGW456L13_845 0.56 -1.5 952,964 - PfGW456L13_845 0.56 -2.6 952,964 - PfGW456L13_845 0.56 -1.1 952,964 - PfGW456L13_845 0.56 -2.6 953,026 + PfGW456L13_845 0.61 -2.8 953,339 - PfGW456L13_845 0.86 -2.0 953,377 + PfGW456L13_845 0.90 -3.1 953,378 - PfGW456L13_845 0.90 -3.6 953,387 - -1.1 953,387 - -2.1 953,387 - -1.3 953,387 - -3.2 953,419 + -0.9 953,419 + -0.9 953,420 - +1.3 953,420 - -3.6 953,420 - -2.1 953,420 - -3.4 953,420 - -2.3 953,420 - -3.4 953,429 + -0.7 953,492 - -2.7 953,495 + -1.9 953,496 - -2.9 953,496 - -3.0 953,496 - -1.9 953,518 + -2.7 953,518 + -1.3 953,518 + -0.7 953,519 - +0.3 953,519 - +0.1 953,519 - -0.1 953,522 - -0.0 953,522 - -0.1 953,522 - +0.0 953,527 + +0.5 953,527 + -1.3 953,528 - +1.4 953,528 - -0.5 953,528 - -0.6 953,720 - PfGW456L13_847 0.33 +0.1 953,720 - PfGW456L13_847 0.33 +0.0 953,720 - PfGW456L13_847 0.33 +0.7 953,734 - PfGW456L13_847 0.38 -0.4 953,735 + PfGW456L13_847 0.38 -0.3 953,759 - PfGW456L13_847 0.47 -0.4 953,830 - PfGW456L13_847 0.72 -1.3 953,858 + PfGW456L13_847 0.82 +0.7 953,859 - PfGW456L13_847 0.83 +0.8 954,122 + PfGW456L13_848 0.65 +0.6 954,190 + PfGW456L13_848 0.85 -0.5 954,190 + PfGW456L13_848 0.85 +0.9 954,191 - PfGW456L13_848 0.86 -0.9 954,191 - PfGW456L13_848 0.86 -0.9 954,283 - +0.6 954,283 - -0.6 954,380 + +1.3 954,380 + -0.1 954,381 - -0.1 954,381 - +1.4 954,381 - -0.4 954,413 + +0.2 954,413 + +0.2 954,414 - +0.0 954,460 - +0.1 954,460 - -0.1
Or see this region's nucleotide sequence