Experiment: Vancomycin 0.125 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_4959 and PfGW456L13_4960 are separated by 57 nucleotides PfGW456L13_4960 and PfGW456L13_4961 are separated by 12 nucleotides PfGW456L13_4961 and PfGW456L13_4962 are separated by 3 nucleotides
PfGW456L13_4959 - Protein sirB1, at 5,537,423 to 5,538,226
_4959
PfGW456L13_4960 - Maleylacetoacetate isomerase (EC 5.2.1.2) @ Glutathione S-transferase, zeta (EC 2.5.1.18), at 5,538,284 to 5,538,919
_4960
PfGW456L13_4961 - Fumarylacetoacetase (EC 3.7.1.2), at 5,538,932 to 5,540,236
_4961
PfGW456L13_4962 - Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (from data) , at 5,540,240 to 5,541,544
_4962
Position (kb)
5538
5539
5540
5541 Strain fitness (log2 ratio)
-2
-1
0
1
2
3 at 5537.990 kb on + strand, within PfGW456L13_4959 at 5537.990 kb on + strand, within PfGW456L13_4959 at 5537.990 kb on + strand, within PfGW456L13_4959 at 5537.990 kb on + strand, within PfGW456L13_4959 at 5537.991 kb on - strand, within PfGW456L13_4959 at 5537.991 kb on - strand, within PfGW456L13_4959 at 5537.991 kb on - strand, within PfGW456L13_4959 at 5537.991 kb on - strand, within PfGW456L13_4959 at 5538.071 kb on + strand, within PfGW456L13_4959 at 5538.072 kb on - strand, within PfGW456L13_4959 at 5538.093 kb on - strand, within PfGW456L13_4959 at 5538.372 kb on + strand, within PfGW456L13_4960 at 5538.426 kb on + strand, within PfGW456L13_4960 at 5538.426 kb on + strand, within PfGW456L13_4960 at 5538.427 kb on - strand, within PfGW456L13_4960 at 5538.427 kb on - strand, within PfGW456L13_4960 at 5538.843 kb on + strand, within PfGW456L13_4960 at 5538.900 kb on + strand at 5538.900 kb on + strand at 5538.903 kb on + strand at 5538.903 kb on + strand at 5538.903 kb on + strand at 5538.903 kb on + strand at 5538.903 kb on + strand at 5538.903 kb on + strand at 5538.904 kb on - strand at 5538.904 kb on - strand at 5538.904 kb on - strand at 5538.904 kb on - strand at 5538.904 kb on - strand at 5538.904 kb on - strand at 5538.904 kb on - strand at 5538.904 kb on - strand at 5538.904 kb on - strand at 5538.904 kb on - strand at 5538.907 kb on + strand at 5538.907 kb on + strand at 5538.907 kb on + strand at 5538.907 kb on + strand at 5538.907 kb on + strand at 5538.907 kb on + strand at 5538.908 kb on - strand at 5538.908 kb on - strand at 5538.908 kb on - strand at 5538.908 kb on - strand at 5538.908 kb on - strand at 5538.908 kb on - strand at 5538.908 kb on - strand at 5538.909 kb on + strand at 5538.909 kb on + strand at 5538.909 kb on + strand at 5538.909 kb on + strand at 5538.909 kb on + strand at 5538.909 kb on + strand at 5538.909 kb on + strand at 5538.910 kb on - strand at 5538.910 kb on - strand at 5538.910 kb on - strand at 5538.910 kb on - strand at 5538.910 kb on - strand at 5538.910 kb on - strand at 5538.910 kb on - strand at 5538.910 kb on - strand at 5538.910 kb on - strand at 5538.910 kb on - strand at 5538.910 kb on - strand at 5539.042 kb on + strand at 5539.042 kb on + strand at 5539.042 kb on + strand at 5539.218 kb on + strand, within PfGW456L13_4961 at 5539.218 kb on + strand, within PfGW456L13_4961 at 5539.218 kb on + strand, within PfGW456L13_4961 at 5539.218 kb on + strand, within PfGW456L13_4961 at 5539.295 kb on + strand, within PfGW456L13_4961 at 5539.295 kb on + strand, within PfGW456L13_4961 at 5539.295 kb on + strand, within PfGW456L13_4961 at 5539.296 kb on - strand, within PfGW456L13_4961 at 5539.296 kb on - strand, within PfGW456L13_4961 at 5539.296 kb on - strand, within PfGW456L13_4961 at 5539.485 kb on + strand, within PfGW456L13_4961 at 5539.755 kb on + strand, within PfGW456L13_4961 at 5539.755 kb on + strand, within PfGW456L13_4961 at 5539.756 kb on - strand, within PfGW456L13_4961 at 5539.756 kb on - strand, within PfGW456L13_4961 at 5539.756 kb on - strand, within PfGW456L13_4961 at 5539.756 kb on - strand, within PfGW456L13_4961 at 5539.756 kb on - strand, within PfGW456L13_4961 at 5539.761 kb on + strand, within PfGW456L13_4961 at 5539.830 kb on + strand, within PfGW456L13_4961 at 5539.830 kb on + strand, within PfGW456L13_4961 at 5539.831 kb on - strand, within PfGW456L13_4961 at 5539.831 kb on - strand, within PfGW456L13_4961 at 5539.843 kb on - strand, within PfGW456L13_4961 at 5539.843 kb on - strand, within PfGW456L13_4961 at 5539.843 kb on - strand, within PfGW456L13_4961 at 5539.843 kb on - strand, within PfGW456L13_4961 at 5539.843 kb on - strand, within PfGW456L13_4961 at 5540.099 kb on - strand, within PfGW456L13_4961 at 5540.099 kb on - strand, within PfGW456L13_4961 at 5540.292 kb on + strand at 5540.292 kb on + strand at 5540.292 kb on + strand at 5540.292 kb on + strand at 5540.292 kb on + strand at 5540.293 kb on - strand at 5540.293 kb on - strand at 5540.293 kb on - strand at 5540.293 kb on - strand at 5540.396 kb on + strand, within PfGW456L13_4962 at 5540.506 kb on - strand, within PfGW456L13_4962 at 5540.724 kb on + strand at 5540.724 kb on + strand, within PfGW456L13_4962 at 5540.724 kb on + strand, within PfGW456L13_4962 at 5540.725 kb on - strand, within PfGW456L13_4962 at 5540.730 kb on + strand, within PfGW456L13_4962 at 5540.731 kb on - strand, within PfGW456L13_4962 at 5540.731 kb on - strand, within PfGW456L13_4962 at 5540.952 kb on + strand, within PfGW456L13_4962 at 5541.142 kb on - strand, within PfGW456L13_4962 at 5541.147 kb on + strand, within PfGW456L13_4962 at 5541.147 kb on + strand, within PfGW456L13_4962 at 5541.147 kb on + strand, within PfGW456L13_4962 at 5541.147 kb on + strand, within PfGW456L13_4962 at 5541.147 kb on + strand, within PfGW456L13_4962 at 5541.148 kb on - strand, within PfGW456L13_4962 at 5541.148 kb on - strand, within PfGW456L13_4962 at 5541.148 kb on - strand, within PfGW456L13_4962 at 5541.148 kb on - strand, within PfGW456L13_4962 at 5541.148 kb on - strand, within PfGW456L13_4962 at 5541.148 kb on - strand, within PfGW456L13_4962 at 5541.148 kb on - strand, within PfGW456L13_4962 at 5541.148 kb on - strand, within PfGW456L13_4962 at 5541.148 kb on - strand, within PfGW456L13_4962 at 5541.148 kb on - strand, within PfGW456L13_4962 at 5541.148 kb on - strand, within PfGW456L13_4962 at 5541.148 kb on - strand, within PfGW456L13_4962 at 5541.148 kb on - strand, within PfGW456L13_4962 at 5541.148 kb on - strand, within PfGW456L13_4962 at 5541.148 kb on - strand, within PfGW456L13_4962
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.125 mg/ml remove 5,537,990 + PfGW456L13_4959 0.71 +2.1 5,537,990 + PfGW456L13_4959 0.71 +0.4 5,537,990 + PfGW456L13_4959 0.71 +0.8 5,537,990 + PfGW456L13_4959 0.71 +0.7 5,537,991 - PfGW456L13_4959 0.71 +1.2 5,537,991 - PfGW456L13_4959 0.71 -0.1 5,537,991 - PfGW456L13_4959 0.71 +0.4 5,537,991 - PfGW456L13_4959 0.71 -0.2 5,538,071 + PfGW456L13_4959 0.81 -0.1 5,538,072 - PfGW456L13_4959 0.81 +0.5 5,538,093 - PfGW456L13_4959 0.83 -0.7 5,538,372 + PfGW456L13_4960 0.14 -0.2 5,538,426 + PfGW456L13_4960 0.22 -0.2 5,538,426 + PfGW456L13_4960 0.22 +1.5 5,538,427 - PfGW456L13_4960 0.22 +1.7 5,538,427 - PfGW456L13_4960 0.22 -0.2 5,538,843 + PfGW456L13_4960 0.88 +0.7 5,538,900 + -0.1 5,538,900 + -0.5 5,538,903 + +0.8 5,538,903 + +0.2 5,538,903 + -0.1 5,538,903 + -0.0 5,538,903 + -0.9 5,538,903 + -0.2 5,538,904 - -0.6 5,538,904 - +0.2 5,538,904 - +2.5 5,538,904 - -0.4 5,538,904 - -0.6 5,538,904 - +1.0 5,538,904 - -1.1 5,538,904 - -1.2 5,538,904 - -0.4 5,538,904 - +0.1 5,538,907 + -0.9 5,538,907 + +0.1 5,538,907 + -1.8 5,538,907 + +0.8 5,538,907 + -0.2 5,538,907 + +0.4 5,538,908 - +0.7 5,538,908 - -0.0 5,538,908 - +0.7 5,538,908 - -0.0 5,538,908 - -2.5 5,538,908 - -0.1 5,538,908 - -0.8 5,538,909 + +0.1 5,538,909 + -0.9 5,538,909 + -0.9 5,538,909 + -0.1 5,538,909 + +2.4 5,538,909 + -0.0 5,538,909 + +1.0 5,538,910 - +1.1 5,538,910 - +0.2 5,538,910 - -0.0 5,538,910 - -0.8 5,538,910 - -0.8 5,538,910 - -0.0 5,538,910 - +0.3 5,538,910 - +0.2 5,538,910 - -0.3 5,538,910 - +0.2 5,538,910 - +0.3 5,539,042 + -0.2 5,539,042 + +0.6 5,539,042 + -1.2 5,539,218 + PfGW456L13_4961 0.22 +1.0 5,539,218 + PfGW456L13_4961 0.22 -0.8 5,539,218 + PfGW456L13_4961 0.22 -0.2 5,539,218 + PfGW456L13_4961 0.22 -0.7 5,539,295 + PfGW456L13_4961 0.28 -0.8 5,539,295 + PfGW456L13_4961 0.28 -0.4 5,539,295 + PfGW456L13_4961 0.28 -1.1 5,539,296 - PfGW456L13_4961 0.28 -0.2 5,539,296 - PfGW456L13_4961 0.28 -2.6 5,539,296 - PfGW456L13_4961 0.28 -1.8 5,539,485 + PfGW456L13_4961 0.42 -0.3 5,539,755 + PfGW456L13_4961 0.63 -0.4 5,539,755 + PfGW456L13_4961 0.63 +0.3 5,539,756 - PfGW456L13_4961 0.63 -2.0 5,539,756 - PfGW456L13_4961 0.63 -0.6 5,539,756 - PfGW456L13_4961 0.63 -0.5 5,539,756 - PfGW456L13_4961 0.63 +0.0 5,539,756 - PfGW456L13_4961 0.63 +0.1 5,539,761 + PfGW456L13_4961 0.64 -0.2 5,539,830 + PfGW456L13_4961 0.69 -2.5 5,539,830 + PfGW456L13_4961 0.69 -2.1 5,539,831 - PfGW456L13_4961 0.69 -0.9 5,539,831 - PfGW456L13_4961 0.69 -1.8 5,539,843 - PfGW456L13_4961 0.70 -0.8 5,539,843 - PfGW456L13_4961 0.70 -2.6 5,539,843 - PfGW456L13_4961 0.70 -2.0 5,539,843 - PfGW456L13_4961 0.70 -2.0 5,539,843 - PfGW456L13_4961 0.70 -1.1 5,540,099 - PfGW456L13_4961 0.89 -0.8 5,540,099 - PfGW456L13_4961 0.89 -1.1 5,540,292 + -0.5 5,540,292 + +0.0 5,540,292 + -0.6 5,540,292 + -0.3 5,540,292 + +0.1 5,540,293 - -0.5 5,540,293 - +0.2 5,540,293 - -0.1 5,540,293 - -0.1 5,540,396 + PfGW456L13_4962 0.12 +0.2 5,540,506 - PfGW456L13_4962 0.20 +0.7 5,540,724 + +2.1 5,540,724 + PfGW456L13_4962 0.37 -2.2 5,540,724 + PfGW456L13_4962 0.37 -1.9 5,540,725 - PfGW456L13_4962 0.37 -2.6 5,540,730 + PfGW456L13_4962 0.38 +2.8 5,540,731 - PfGW456L13_4962 0.38 +0.5 5,540,731 - PfGW456L13_4962 0.38 +2.0 5,540,952 + PfGW456L13_4962 0.55 +0.5 5,541,142 - PfGW456L13_4962 0.69 +1.2 5,541,147 + PfGW456L13_4962 0.70 -0.5 5,541,147 + PfGW456L13_4962 0.70 -0.1 5,541,147 + PfGW456L13_4962 0.70 +0.1 5,541,147 + PfGW456L13_4962 0.70 +0.8 5,541,147 + PfGW456L13_4962 0.70 -0.1 5,541,148 - PfGW456L13_4962 0.70 +0.1 5,541,148 - PfGW456L13_4962 0.70 -1.1 5,541,148 - PfGW456L13_4962 0.70 +1.7 5,541,148 - PfGW456L13_4962 0.70 -0.1 5,541,148 - PfGW456L13_4962 0.70 -0.5 5,541,148 - PfGW456L13_4962 0.70 +1.5 5,541,148 - PfGW456L13_4962 0.70 +0.9 5,541,148 - PfGW456L13_4962 0.70 -1.0 5,541,148 - PfGW456L13_4962 0.70 +0.6 5,541,148 - PfGW456L13_4962 0.70 +0.3 5,541,148 - PfGW456L13_4962 0.70 -0.1 5,541,148 - PfGW456L13_4962 0.70 -0.6 5,541,148 - PfGW456L13_4962 0.70 -0.9 5,541,148 - PfGW456L13_4962 0.70 -1.6 5,541,148 - PfGW456L13_4962 0.70 -0.2
Or see this region's nucleotide sequence