Experiment: Vancomycin 0.125 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_4579 and PfGW456L13_4580 are separated by 278 nucleotides PfGW456L13_4580 and PfGW456L13_4581 are separated by 3 nucleotides
PfGW456L13_4579 - Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family, at 5,108,607 to 5,109,239
_4579
PfGW456L13_4580 - Multidrug efflux RND membrane fusion protein MexC, at 5,109,518 to 5,110,675
_4580
PfGW456L13_4581 - RND efflux system, inner membrane transporter CmeB, at 5,110,679 to 5,113,840
_4581
Position (kb)
5109
5110
5111 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 5108.547 kb on + strand at 5108.547 kb on + strand at 5108.595 kb on + strand at 5108.596 kb on - strand at 5108.729 kb on + strand, within PfGW456L13_4579 at 5108.729 kb on + strand, within PfGW456L13_4579 at 5108.729 kb on + strand, within PfGW456L13_4579 at 5108.729 kb on + strand, within PfGW456L13_4579 at 5108.730 kb on - strand, within PfGW456L13_4579 at 5108.730 kb on - strand, within PfGW456L13_4579 at 5108.730 kb on - strand, within PfGW456L13_4579 at 5108.730 kb on - strand, within PfGW456L13_4579 at 5108.730 kb on - strand, within PfGW456L13_4579 at 5108.730 kb on - strand, within PfGW456L13_4579 at 5108.730 kb on - strand, within PfGW456L13_4579 at 5108.730 kb on - strand, within PfGW456L13_4579 at 5108.730 kb on - strand, within PfGW456L13_4579 at 5108.730 kb on - strand, within PfGW456L13_4579 at 5108.730 kb on - strand, within PfGW456L13_4579 at 5108.730 kb on - strand, within PfGW456L13_4579 at 5108.731 kb on + strand, within PfGW456L13_4579 at 5108.731 kb on + strand, within PfGW456L13_4579 at 5108.731 kb on + strand, within PfGW456L13_4579 at 5108.731 kb on + strand, within PfGW456L13_4579 at 5108.731 kb on + strand, within PfGW456L13_4579 at 5108.731 kb on + strand, within PfGW456L13_4579 at 5108.731 kb on + strand, within PfGW456L13_4579 at 5108.731 kb on + strand, within PfGW456L13_4579 at 5108.732 kb on - strand, within PfGW456L13_4579 at 5108.732 kb on - strand, within PfGW456L13_4579 at 5108.732 kb on - strand, within PfGW456L13_4579 at 5108.732 kb on - strand, within PfGW456L13_4579 at 5108.732 kb on - strand, within PfGW456L13_4579 at 5108.732 kb on - strand, within PfGW456L13_4579 at 5108.732 kb on - strand, within PfGW456L13_4579 at 5108.732 kb on - strand, within PfGW456L13_4579 at 5108.732 kb on - strand, within PfGW456L13_4579 at 5108.732 kb on - strand, within PfGW456L13_4579 at 5108.732 kb on - strand, within PfGW456L13_4579 at 5108.732 kb on - strand, within PfGW456L13_4579 at 5108.732 kb on - strand, within PfGW456L13_4579 at 5108.802 kb on - strand, within PfGW456L13_4579 at 5108.802 kb on - strand, within PfGW456L13_4579 at 5108.895 kb on - strand, within PfGW456L13_4579 at 5109.094 kb on + strand, within PfGW456L13_4579 at 5109.094 kb on + strand, within PfGW456L13_4579 at 5109.094 kb on + strand, within PfGW456L13_4579 at 5109.095 kb on - strand, within PfGW456L13_4579 at 5109.095 kb on - strand, within PfGW456L13_4579 at 5109.227 kb on + strand at 5109.245 kb on + strand at 5109.245 kb on + strand at 5109.246 kb on - strand at 5109.246 kb on - strand at 5109.246 kb on - strand at 5109.246 kb on - strand at 5109.246 kb on - strand at 5109.246 kb on - strand at 5109.246 kb on - strand at 5109.246 kb on - strand at 5109.246 kb on - strand at 5109.246 kb on - strand at 5109.246 kb on - strand at 5109.292 kb on + strand at 5109.293 kb on - strand at 5109.332 kb on + strand at 5109.333 kb on - strand at 5109.398 kb on - strand at 5109.415 kb on + strand at 5109.415 kb on + strand at 5109.415 kb on + strand at 5109.415 kb on + strand at 5109.416 kb on - strand at 5109.440 kb on + strand at 5109.441 kb on - strand at 5109.441 kb on - strand at 5109.444 kb on + strand at 5109.483 kb on - strand at 5109.483 kb on - strand at 5109.483 kb on - strand at 5109.685 kb on + strand, within PfGW456L13_4580 at 5109.788 kb on + strand, within PfGW456L13_4580 at 5109.809 kb on + strand, within PfGW456L13_4580 at 5109.810 kb on - strand, within PfGW456L13_4580 at 5109.810 kb on - strand, within PfGW456L13_4580 at 5109.915 kb on - strand, within PfGW456L13_4580 at 5109.915 kb on - strand, within PfGW456L13_4580 at 5109.983 kb on + strand, within PfGW456L13_4580 at 5109.995 kb on + strand, within PfGW456L13_4580 at 5109.995 kb on + strand, within PfGW456L13_4580 at 5109.995 kb on + strand, within PfGW456L13_4580 at 5109.995 kb on + strand, within PfGW456L13_4580 at 5109.995 kb on + strand, within PfGW456L13_4580 at 5110.103 kb on + strand, within PfGW456L13_4580 at 5110.104 kb on - strand, within PfGW456L13_4580 at 5110.104 kb on - strand, within PfGW456L13_4580 at 5110.104 kb on - strand, within PfGW456L13_4580 at 5110.229 kb on + strand, within PfGW456L13_4580 at 5110.230 kb on - strand, within PfGW456L13_4580 at 5110.345 kb on - strand, within PfGW456L13_4580 at 5110.611 kb on + strand at 5110.612 kb on - strand at 5110.641 kb on + strand at 5110.641 kb on + strand at 5110.641 kb on + strand at 5110.641 kb on + strand at 5110.642 kb on - strand at 5110.642 kb on - strand at 5110.673 kb on + strand at 5110.673 kb on + strand at 5110.673 kb on + strand at 5110.674 kb on - strand at 5110.719 kb on + strand at 5110.719 kb on + strand at 5110.720 kb on - strand at 5110.907 kb on + strand at 5110.907 kb on + strand at 5110.907 kb on + strand at 5110.907 kb on + strand at 5110.908 kb on - strand at 5110.924 kb on + strand at 5110.924 kb on + strand at 5110.924 kb on + strand at 5111.056 kb on + strand, within PfGW456L13_4581 at 5111.057 kb on - strand, within PfGW456L13_4581 at 5111.057 kb on - strand, within PfGW456L13_4581 at 5111.057 kb on - strand, within PfGW456L13_4581 at 5111.057 kb on - strand, within PfGW456L13_4581 at 5111.147 kb on + strand, within PfGW456L13_4581 at 5111.147 kb on + strand, within PfGW456L13_4581 at 5111.147 kb on + strand, within PfGW456L13_4581 at 5111.148 kb on - strand, within PfGW456L13_4581 at 5111.148 kb on - strand, within PfGW456L13_4581 at 5111.148 kb on - strand, within PfGW456L13_4581 at 5111.148 kb on - strand, within PfGW456L13_4581 at 5111.148 kb on - strand, within PfGW456L13_4581 at 5111.148 kb on - strand, within PfGW456L13_4581 at 5111.148 kb on - strand, within PfGW456L13_4581 at 5111.222 kb on + strand, within PfGW456L13_4581 at 5111.501 kb on + strand, within PfGW456L13_4581 at 5111.501 kb on + strand, within PfGW456L13_4581 at 5111.501 kb on + strand, within PfGW456L13_4581 at 5111.501 kb on + strand, within PfGW456L13_4581 at 5111.501 kb on + strand, within PfGW456L13_4581 at 5111.501 kb on + strand, within PfGW456L13_4581 at 5111.502 kb on - strand, within PfGW456L13_4581 at 5111.502 kb on - strand, within PfGW456L13_4581 at 5111.658 kb on - strand, within PfGW456L13_4581
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.125 mg/ml remove 5,108,547 + +0.2 5,108,547 + +0.4 5,108,595 + +1.3 5,108,596 - +0.1 5,108,729 + PfGW456L13_4579 0.19 +0.6 5,108,729 + PfGW456L13_4579 0.19 +1.3 5,108,729 + PfGW456L13_4579 0.19 +0.7 5,108,729 + PfGW456L13_4579 0.19 +0.7 5,108,730 - PfGW456L13_4579 0.19 +0.9 5,108,730 - PfGW456L13_4579 0.19 +0.9 5,108,730 - PfGW456L13_4579 0.19 +1.1 5,108,730 - PfGW456L13_4579 0.19 -0.8 5,108,730 - PfGW456L13_4579 0.19 -0.9 5,108,730 - PfGW456L13_4579 0.19 +0.1 5,108,730 - PfGW456L13_4579 0.19 -1.1 5,108,730 - PfGW456L13_4579 0.19 -0.7 5,108,730 - PfGW456L13_4579 0.19 +1.2 5,108,730 - PfGW456L13_4579 0.19 +1.0 5,108,730 - PfGW456L13_4579 0.19 -1.9 5,108,730 - PfGW456L13_4579 0.19 +0.0 5,108,731 + PfGW456L13_4579 0.20 -0.5 5,108,731 + PfGW456L13_4579 0.20 +0.9 5,108,731 + PfGW456L13_4579 0.20 +0.7 5,108,731 + PfGW456L13_4579 0.20 -0.3 5,108,731 + PfGW456L13_4579 0.20 +0.7 5,108,731 + PfGW456L13_4579 0.20 +1.1 5,108,731 + PfGW456L13_4579 0.20 -0.5 5,108,731 + PfGW456L13_4579 0.20 -0.1 5,108,732 - PfGW456L13_4579 0.20 +0.3 5,108,732 - PfGW456L13_4579 0.20 +0.3 5,108,732 - PfGW456L13_4579 0.20 +0.3 5,108,732 - PfGW456L13_4579 0.20 -0.6 5,108,732 - PfGW456L13_4579 0.20 +0.7 5,108,732 - PfGW456L13_4579 0.20 +0.1 5,108,732 - PfGW456L13_4579 0.20 +0.0 5,108,732 - PfGW456L13_4579 0.20 -0.5 5,108,732 - PfGW456L13_4579 0.20 +0.2 5,108,732 - PfGW456L13_4579 0.20 +0.4 5,108,732 - PfGW456L13_4579 0.20 +0.5 5,108,732 - PfGW456L13_4579 0.20 -0.1 5,108,732 - PfGW456L13_4579 0.20 +0.7 5,108,802 - PfGW456L13_4579 0.31 +1.4 5,108,802 - PfGW456L13_4579 0.31 +1.4 5,108,895 - PfGW456L13_4579 0.45 -1.1 5,109,094 + PfGW456L13_4579 0.77 -0.1 5,109,094 + PfGW456L13_4579 0.77 +1.0 5,109,094 + PfGW456L13_4579 0.77 -0.1 5,109,095 - PfGW456L13_4579 0.77 +0.6 5,109,095 - PfGW456L13_4579 0.77 +0.1 5,109,227 + +0.3 5,109,245 + -0.1 5,109,245 + +0.4 5,109,246 - +0.5 5,109,246 - -0.3 5,109,246 - +1.0 5,109,246 - -0.1 5,109,246 - +0.3 5,109,246 - -0.5 5,109,246 - -0.9 5,109,246 - -0.6 5,109,246 - +1.3 5,109,246 - +0.1 5,109,246 - -1.0 5,109,292 + +0.5 5,109,293 - -0.5 5,109,332 + +0.2 5,109,333 - +0.4 5,109,398 - +0.1 5,109,415 + -0.1 5,109,415 + +1.5 5,109,415 + +0.4 5,109,415 + +0.0 5,109,416 - -0.7 5,109,440 + +0.4 5,109,441 - -1.3 5,109,441 - -0.5 5,109,444 + +1.5 5,109,483 - -0.7 5,109,483 - -0.9 5,109,483 - -3.0 5,109,685 + PfGW456L13_4580 0.14 -1.9 5,109,788 + PfGW456L13_4580 0.23 -0.9 5,109,809 + PfGW456L13_4580 0.25 -2.6 5,109,810 - PfGW456L13_4580 0.25 -0.6 5,109,810 - PfGW456L13_4580 0.25 -1.8 5,109,915 - PfGW456L13_4580 0.34 -0.8 5,109,915 - PfGW456L13_4580 0.34 -1.4 5,109,983 + PfGW456L13_4580 0.40 -1.3 5,109,995 + PfGW456L13_4580 0.41 -0.9 5,109,995 + PfGW456L13_4580 0.41 +0.4 5,109,995 + PfGW456L13_4580 0.41 -1.1 5,109,995 + PfGW456L13_4580 0.41 -0.6 5,109,995 + PfGW456L13_4580 0.41 -1.1 5,110,103 + PfGW456L13_4580 0.51 +2.7 5,110,104 - PfGW456L13_4580 0.51 -1.4 5,110,104 - PfGW456L13_4580 0.51 -0.3 5,110,104 - PfGW456L13_4580 0.51 -2.3 5,110,229 + PfGW456L13_4580 0.61 -1.5 5,110,230 - PfGW456L13_4580 0.61 -0.3 5,110,345 - PfGW456L13_4580 0.71 -1.1 5,110,611 + -0.1 5,110,612 - +0.1 5,110,641 + -0.2 5,110,641 + -0.4 5,110,641 + +0.2 5,110,641 + -1.8 5,110,642 - -1.0 5,110,642 - -1.1 5,110,673 + -0.4 5,110,673 + -0.2 5,110,673 + -3.3 5,110,674 - +1.4 5,110,719 + -0.3 5,110,719 + +0.1 5,110,720 - -0.1 5,110,907 + -0.7 5,110,907 + -2.1 5,110,907 + -0.9 5,110,907 + -1.0 5,110,908 - -0.5 5,110,924 + -0.6 5,110,924 + -1.6 5,110,924 + -0.5 5,111,056 + PfGW456L13_4581 0.12 +0.4 5,111,057 - PfGW456L13_4581 0.12 +0.4 5,111,057 - PfGW456L13_4581 0.12 -1.3 5,111,057 - PfGW456L13_4581 0.12 -2.3 5,111,057 - PfGW456L13_4581 0.12 +0.2 5,111,147 + PfGW456L13_4581 0.15 -0.6 5,111,147 + PfGW456L13_4581 0.15 +0.0 5,111,147 + PfGW456L13_4581 0.15 -1.6 5,111,148 - PfGW456L13_4581 0.15 +0.3 5,111,148 - PfGW456L13_4581 0.15 -0.1 5,111,148 - PfGW456L13_4581 0.15 +0.7 5,111,148 - PfGW456L13_4581 0.15 -0.5 5,111,148 - PfGW456L13_4581 0.15 -1.3 5,111,148 - PfGW456L13_4581 0.15 -0.3 5,111,148 - PfGW456L13_4581 0.15 -0.2 5,111,222 + PfGW456L13_4581 0.17 -0.3 5,111,501 + PfGW456L13_4581 0.26 -1.3 5,111,501 + PfGW456L13_4581 0.26 -1.1 5,111,501 + PfGW456L13_4581 0.26 -0.3 5,111,501 + PfGW456L13_4581 0.26 -1.3 5,111,501 + PfGW456L13_4581 0.26 -3.3 5,111,501 + PfGW456L13_4581 0.26 +0.2 5,111,502 - PfGW456L13_4581 0.26 +0.3 5,111,502 - PfGW456L13_4581 0.26 -1.5 5,111,658 - PfGW456L13_4581 0.31 -1.2
Or see this region's nucleotide sequence