Experiment: Vancomycin 0.125 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_2344 and PfGW456L13_2345 are separated by 74 nucleotides PfGW456L13_2345 and PfGW456L13_2346 are separated by 46 nucleotides PfGW456L13_2346 and PfGW456L13_2347 are separated by 64 nucleotides PfGW456L13_2347 and PfGW456L13_2348 are separated by 46 nucleotides
PfGW456L13_2344 - SAM-dependent methyltransferases, at 2,577,071 to 2,577,904
_2344
PfGW456L13_2345 - 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100), at 2,577,979 to 2,578,767
_2345
PfGW456L13_2346 - glutamine ABC transporter ATP-binding component, at 2,578,814 to 2,580,361
_2346
PfGW456L13_2347 - Arginine ABC transporter, periplasmic arginine-binding protein ArtJ, at 2,580,426 to 2,581,220
_2347
PfGW456L13_2348 - 2-Oxobutyrate oxidase, putative, at 2,581,267 to 2,582,337
_2348
Position (kb)
2578
2579
2580
2581 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 2577.912 kb on + strand at 2577.912 kb on + strand at 2577.956 kb on + strand at 2577.967 kb on - strand at 2577.967 kb on - strand at 2577.967 kb on - strand at 2578.276 kb on - strand, within PfGW456L13_2345 at 2578.386 kb on + strand, within PfGW456L13_2345 at 2578.595 kb on - strand, within PfGW456L13_2345 at 2578.732 kb on + strand at 2578.754 kb on - strand at 2578.803 kb on + strand at 2578.803 kb on + strand at 2578.804 kb on - strand at 2578.804 kb on - strand at 2578.812 kb on - strand at 2578.812 kb on - strand at 2578.812 kb on - strand at 2578.933 kb on + strand at 2578.934 kb on - strand at 2578.934 kb on - strand at 2578.936 kb on + strand at 2578.936 kb on + strand at 2578.937 kb on - strand at 2578.937 kb on - strand at 2578.952 kb on + strand at 2578.953 kb on - strand at 2578.953 kb on - strand at 2579.175 kb on + strand, within PfGW456L13_2346 at 2579.176 kb on - strand, within PfGW456L13_2346 at 2579.220 kb on + strand, within PfGW456L13_2346 at 2579.221 kb on - strand, within PfGW456L13_2346 at 2579.221 kb on - strand, within PfGW456L13_2346 at 2579.657 kb on + strand, within PfGW456L13_2346 at 2579.757 kb on + strand, within PfGW456L13_2346 at 2579.757 kb on + strand, within PfGW456L13_2346 at 2579.757 kb on + strand, within PfGW456L13_2346 at 2579.757 kb on + strand, within PfGW456L13_2346 at 2579.758 kb on - strand, within PfGW456L13_2346 at 2579.758 kb on - strand, within PfGW456L13_2346 at 2579.758 kb on - strand, within PfGW456L13_2346 at 2579.758 kb on - strand, within PfGW456L13_2346 at 2579.760 kb on + strand, within PfGW456L13_2346 at 2579.760 kb on + strand, within PfGW456L13_2346 at 2579.761 kb on - strand, within PfGW456L13_2346 at 2579.761 kb on - strand, within PfGW456L13_2346 at 2579.761 kb on - strand, within PfGW456L13_2346 at 2579.808 kb on + strand, within PfGW456L13_2346 at 2579.809 kb on - strand, within PfGW456L13_2346 at 2579.886 kb on + strand, within PfGW456L13_2346 at 2579.886 kb on + strand, within PfGW456L13_2346 at 2579.886 kb on + strand, within PfGW456L13_2346 at 2579.886 kb on + strand, within PfGW456L13_2346 at 2579.886 kb on + strand, within PfGW456L13_2346 at 2579.886 kb on + strand, within PfGW456L13_2346 at 2579.886 kb on + strand, within PfGW456L13_2346 at 2579.887 kb on - strand, within PfGW456L13_2346 at 2579.887 kb on - strand, within PfGW456L13_2346 at 2579.887 kb on - strand, within PfGW456L13_2346 at 2579.887 kb on - strand, within PfGW456L13_2346 at 2579.887 kb on - strand, within PfGW456L13_2346 at 2579.914 kb on + strand, within PfGW456L13_2346 at 2579.915 kb on - strand, within PfGW456L13_2346 at 2579.915 kb on - strand, within PfGW456L13_2346 at 2580.039 kb on + strand, within PfGW456L13_2346 at 2580.039 kb on + strand, within PfGW456L13_2346 at 2580.039 kb on + strand, within PfGW456L13_2346 at 2580.039 kb on + strand, within PfGW456L13_2346 at 2580.039 kb on + strand, within PfGW456L13_2346 at 2580.040 kb on - strand, within PfGW456L13_2346 at 2580.040 kb on - strand, within PfGW456L13_2346 at 2580.040 kb on - strand, within PfGW456L13_2346 at 2580.079 kb on - strand, within PfGW456L13_2346 at 2580.079 kb on - strand, within PfGW456L13_2346 at 2580.079 kb on - strand, within PfGW456L13_2346 at 2580.132 kb on + strand, within PfGW456L13_2346 at 2580.132 kb on + strand, within PfGW456L13_2346 at 2580.133 kb on - strand, within PfGW456L13_2346 at 2580.133 kb on - strand, within PfGW456L13_2346 at 2580.183 kb on + strand, within PfGW456L13_2346 at 2580.183 kb on + strand, within PfGW456L13_2346 at 2580.183 kb on + strand, within PfGW456L13_2346 at 2580.184 kb on - strand, within PfGW456L13_2346 at 2580.184 kb on - strand, within PfGW456L13_2346 at 2580.184 kb on - strand, within PfGW456L13_2346 at 2580.184 kb on - strand, within PfGW456L13_2346 at 2580.342 kb on + strand at 2580.342 kb on + strand at 2580.342 kb on + strand at 2580.342 kb on + strand at 2580.342 kb on + strand at 2580.411 kb on + strand at 2580.412 kb on - strand at 2580.412 kb on - strand at 2580.412 kb on - strand at 2580.412 kb on - strand at 2580.428 kb on - strand at 2580.428 kb on - strand at 2580.428 kb on - strand at 2580.454 kb on + strand at 2580.454 kb on + strand at 2580.455 kb on - strand at 2580.455 kb on - strand at 2580.571 kb on + strand, within PfGW456L13_2347 at 2580.572 kb on - strand, within PfGW456L13_2347 at 2580.749 kb on - strand, within PfGW456L13_2347 at 2580.749 kb on - strand, within PfGW456L13_2347 at 2580.931 kb on + strand, within PfGW456L13_2347 at 2580.931 kb on + strand, within PfGW456L13_2347 at 2580.931 kb on + strand, within PfGW456L13_2347 at 2580.931 kb on + strand, within PfGW456L13_2347 at 2580.931 kb on + strand, within PfGW456L13_2347 at 2580.931 kb on + strand, within PfGW456L13_2347 at 2580.931 kb on + strand, within PfGW456L13_2347 at 2580.931 kb on + strand, within PfGW456L13_2347 at 2580.931 kb on + strand, within PfGW456L13_2347 at 2580.931 kb on + strand, within PfGW456L13_2347 at 2580.931 kb on + strand, within PfGW456L13_2347 at 2580.931 kb on + strand, within PfGW456L13_2347 at 2580.931 kb on + strand, within PfGW456L13_2347 at 2580.931 kb on + strand, within PfGW456L13_2347 at 2580.931 kb on + strand, within PfGW456L13_2347 at 2580.932 kb on - strand, within PfGW456L13_2347 at 2580.932 kb on - strand, within PfGW456L13_2347 at 2580.932 kb on - strand, within PfGW456L13_2347 at 2580.932 kb on - strand, within PfGW456L13_2347 at 2580.932 kb on - strand, within PfGW456L13_2347 at 2580.932 kb on - strand, within PfGW456L13_2347 at 2580.932 kb on - strand, within PfGW456L13_2347 at 2580.932 kb on - strand, within PfGW456L13_2347 at 2580.932 kb on - strand, within PfGW456L13_2347 at 2580.932 kb on - strand, within PfGW456L13_2347 at 2580.932 kb on - strand, within PfGW456L13_2347 at 2580.932 kb on - strand, within PfGW456L13_2347 at 2581.087 kb on + strand, within PfGW456L13_2347 at 2581.087 kb on + strand, within PfGW456L13_2347 at 2581.087 kb on + strand, within PfGW456L13_2347 at 2581.087 kb on + strand, within PfGW456L13_2347 at 2581.088 kb on - strand, within PfGW456L13_2347 at 2581.088 kb on - strand, within PfGW456L13_2347 at 2581.105 kb on + strand, within PfGW456L13_2347 at 2581.105 kb on + strand, within PfGW456L13_2347 at 2581.106 kb on - strand, within PfGW456L13_2347 at 2581.106 kb on - strand, within PfGW456L13_2347 at 2581.106 kb on - strand at 2581.182 kb on + strand at 2581.182 kb on + strand at 2581.183 kb on - strand at 2581.225 kb on + strand at 2581.225 kb on + strand at 2581.225 kb on + strand at 2581.225 kb on + strand at 2581.226 kb on - strand at 2581.226 kb on - strand at 2581.226 kb on - strand at 2581.226 kb on - strand at 2581.226 kb on - strand at 2581.226 kb on - strand at 2581.239 kb on + strand at 2581.240 kb on - strand at 2581.244 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.125 mg/ml remove 2,577,912 + -0.4 2,577,912 + -0.6 2,577,956 + +1.1 2,577,967 - -0.1 2,577,967 - +1.2 2,577,967 - -0.9 2,578,276 - PfGW456L13_2345 0.38 +0.4 2,578,386 + PfGW456L13_2345 0.52 +1.4 2,578,595 - PfGW456L13_2345 0.78 +0.9 2,578,732 + +0.5 2,578,754 - +0.0 2,578,803 + -1.5 2,578,803 + -0.6 2,578,804 - -0.8 2,578,804 - +2.0 2,578,812 - +0.4 2,578,812 - +0.3 2,578,812 - -1.2 2,578,933 + +1.4 2,578,934 - +0.6 2,578,934 - -0.6 2,578,936 + +0.6 2,578,936 + -0.7 2,578,937 - -0.6 2,578,937 - -1.2 2,578,952 + +0.2 2,578,953 - +0.4 2,578,953 - +0.4 2,579,175 + PfGW456L13_2346 0.23 +0.6 2,579,176 - PfGW456L13_2346 0.23 +0.8 2,579,220 + PfGW456L13_2346 0.26 -1.6 2,579,221 - PfGW456L13_2346 0.26 +1.3 2,579,221 - PfGW456L13_2346 0.26 -0.7 2,579,657 + PfGW456L13_2346 0.54 -0.1 2,579,757 + PfGW456L13_2346 0.61 +0.4 2,579,757 + PfGW456L13_2346 0.61 -0.3 2,579,757 + PfGW456L13_2346 0.61 +0.9 2,579,757 + PfGW456L13_2346 0.61 +0.0 2,579,758 - PfGW456L13_2346 0.61 -0.6 2,579,758 - PfGW456L13_2346 0.61 +0.4 2,579,758 - PfGW456L13_2346 0.61 -0.5 2,579,758 - PfGW456L13_2346 0.61 +0.2 2,579,760 + PfGW456L13_2346 0.61 +0.2 2,579,760 + PfGW456L13_2346 0.61 +0.6 2,579,761 - PfGW456L13_2346 0.61 -0.1 2,579,761 - PfGW456L13_2346 0.61 -0.2 2,579,761 - PfGW456L13_2346 0.61 -0.4 2,579,808 + PfGW456L13_2346 0.64 +0.2 2,579,809 - PfGW456L13_2346 0.64 +0.5 2,579,886 + PfGW456L13_2346 0.69 -0.4 2,579,886 + PfGW456L13_2346 0.69 -0.4 2,579,886 + PfGW456L13_2346 0.69 -1.4 2,579,886 + PfGW456L13_2346 0.69 -0.1 2,579,886 + PfGW456L13_2346 0.69 -1.3 2,579,886 + PfGW456L13_2346 0.69 -1.5 2,579,886 + PfGW456L13_2346 0.69 -0.1 2,579,887 - PfGW456L13_2346 0.69 -0.8 2,579,887 - PfGW456L13_2346 0.69 +0.8 2,579,887 - PfGW456L13_2346 0.69 +1.4 2,579,887 - PfGW456L13_2346 0.69 +0.2 2,579,887 - PfGW456L13_2346 0.69 +0.1 2,579,914 + PfGW456L13_2346 0.71 +0.0 2,579,915 - PfGW456L13_2346 0.71 +0.0 2,579,915 - PfGW456L13_2346 0.71 -0.7 2,580,039 + PfGW456L13_2346 0.79 -0.1 2,580,039 + PfGW456L13_2346 0.79 -0.5 2,580,039 + PfGW456L13_2346 0.79 -0.5 2,580,039 + PfGW456L13_2346 0.79 -0.4 2,580,039 + PfGW456L13_2346 0.79 -1.1 2,580,040 - PfGW456L13_2346 0.79 -0.1 2,580,040 - PfGW456L13_2346 0.79 +0.7 2,580,040 - PfGW456L13_2346 0.79 +0.8 2,580,079 - PfGW456L13_2346 0.82 +1.0 2,580,079 - PfGW456L13_2346 0.82 -0.7 2,580,079 - PfGW456L13_2346 0.82 -0.4 2,580,132 + PfGW456L13_2346 0.85 -0.3 2,580,132 + PfGW456L13_2346 0.85 -0.1 2,580,133 - PfGW456L13_2346 0.85 +0.6 2,580,133 - PfGW456L13_2346 0.85 -0.8 2,580,183 + PfGW456L13_2346 0.88 -0.2 2,580,183 + PfGW456L13_2346 0.88 -1.4 2,580,183 + PfGW456L13_2346 0.88 -0.2 2,580,184 - PfGW456L13_2346 0.89 +0.2 2,580,184 - PfGW456L13_2346 0.89 -0.6 2,580,184 - PfGW456L13_2346 0.89 -0.8 2,580,184 - PfGW456L13_2346 0.89 +0.8 2,580,342 + -0.1 2,580,342 + -0.1 2,580,342 + +0.3 2,580,342 + -0.1 2,580,342 + -0.9 2,580,411 + +0.8 2,580,412 - +0.9 2,580,412 - -2.6 2,580,412 - +1.0 2,580,412 - +2.0 2,580,428 - +0.6 2,580,428 - -0.3 2,580,428 - +0.5 2,580,454 + -1.0 2,580,454 + +0.3 2,580,455 - +0.0 2,580,455 - -0.9 2,580,571 + PfGW456L13_2347 0.18 +0.3 2,580,572 - PfGW456L13_2347 0.18 -0.1 2,580,749 - PfGW456L13_2347 0.41 -0.1 2,580,749 - PfGW456L13_2347 0.41 -0.5 2,580,931 + PfGW456L13_2347 0.64 -0.5 2,580,931 + PfGW456L13_2347 0.64 -0.7 2,580,931 + PfGW456L13_2347 0.64 +0.6 2,580,931 + PfGW456L13_2347 0.64 +0.1 2,580,931 + PfGW456L13_2347 0.64 +0.3 2,580,931 + PfGW456L13_2347 0.64 -0.1 2,580,931 + PfGW456L13_2347 0.64 -1.0 2,580,931 + PfGW456L13_2347 0.64 -1.2 2,580,931 + PfGW456L13_2347 0.64 +0.4 2,580,931 + PfGW456L13_2347 0.64 -2.3 2,580,931 + PfGW456L13_2347 0.64 +0.0 2,580,931 + PfGW456L13_2347 0.64 +0.0 2,580,931 + PfGW456L13_2347 0.64 +0.4 2,580,931 + PfGW456L13_2347 0.64 +0.2 2,580,931 + PfGW456L13_2347 0.64 +0.0 2,580,932 - PfGW456L13_2347 0.64 -1.2 2,580,932 - PfGW456L13_2347 0.64 -0.2 2,580,932 - PfGW456L13_2347 0.64 +0.2 2,580,932 - PfGW456L13_2347 0.64 +0.2 2,580,932 - PfGW456L13_2347 0.64 +0.2 2,580,932 - PfGW456L13_2347 0.64 -0.4 2,580,932 - PfGW456L13_2347 0.64 -0.6 2,580,932 - PfGW456L13_2347 0.64 +0.2 2,580,932 - PfGW456L13_2347 0.64 -0.1 2,580,932 - PfGW456L13_2347 0.64 -0.3 2,580,932 - PfGW456L13_2347 0.64 +0.6 2,580,932 - PfGW456L13_2347 0.64 +0.3 2,581,087 + PfGW456L13_2347 0.83 -0.1 2,581,087 + PfGW456L13_2347 0.83 +0.9 2,581,087 + PfGW456L13_2347 0.83 +0.0 2,581,087 + PfGW456L13_2347 0.83 -0.9 2,581,088 - PfGW456L13_2347 0.83 -0.8 2,581,088 - PfGW456L13_2347 0.83 -0.7 2,581,105 + PfGW456L13_2347 0.85 -0.1 2,581,105 + PfGW456L13_2347 0.85 -0.1 2,581,106 - PfGW456L13_2347 0.86 -0.1 2,581,106 - PfGW456L13_2347 0.86 +0.0 2,581,106 - +2.2 2,581,182 + +0.5 2,581,182 + +0.8 2,581,183 - -1.1 2,581,225 + -2.4 2,581,225 + -0.6 2,581,225 + -0.7 2,581,225 + -0.4 2,581,226 - +0.6 2,581,226 - -0.3 2,581,226 - -0.5 2,581,226 - -2.1 2,581,226 - +0.1 2,581,226 - +1.6 2,581,239 + +0.4 2,581,240 - -0.3 2,581,244 - -0.7
Or see this region's nucleotide sequence