Experiment: Vancomycin 0.125 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_2223 and PfGW456L13_2224 are separated by 87 nucleotides PfGW456L13_2224 and PfGW456L13_2225 are separated by 187 nucleotides PfGW456L13_2225 and PfGW456L13_2226 are separated by 208 nucleotides
PfGW456L13_2223 - Glutamate synthase [NADPH] large chain (EC 1.4.1.13), at 2,441,151 to 2,441,438
_2223
PfGW456L13_2224 - 2-keto-3-deoxy-D-arabino-heptulosonate-7- phosphate synthase I alpha (EC 2.5.1.54), at 2,441,526 to 2,442,602
_2224
PfGW456L13_2225 - FIG00958794: hypothetical protein, at 2,442,790 to 2,443,074
_2225
PfGW456L13_2226 - Possible periplasmic thiredoxin, at 2,443,283 to 2,443,618
_2226
Position (kb)
2441
2442
2443 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2
3 at 2440.534 kb on + strand at 2440.535 kb on - strand at 2440.535 kb on - strand at 2440.535 kb on - strand at 2440.537 kb on + strand at 2440.538 kb on - strand at 2440.538 kb on - strand at 2440.538 kb on - strand at 2440.541 kb on + strand at 2440.541 kb on + strand at 2440.541 kb on + strand at 2440.541 kb on + strand at 2440.541 kb on + strand at 2440.542 kb on - strand at 2440.542 kb on - strand at 2440.542 kb on - strand at 2440.542 kb on - strand at 2440.542 kb on - strand at 2440.542 kb on - strand at 2440.542 kb on - strand at 2440.545 kb on + strand at 2440.545 kb on + strand at 2440.545 kb on + strand at 2440.545 kb on + strand at 2440.545 kb on + strand at 2440.546 kb on - strand at 2440.546 kb on - strand at 2440.546 kb on - strand at 2440.546 kb on - strand at 2440.546 kb on - strand at 2440.546 kb on - strand at 2440.575 kb on + strand at 2440.575 kb on + strand at 2440.576 kb on - strand at 2440.576 kb on - strand at 2440.579 kb on + strand at 2440.579 kb on + strand at 2440.579 kb on + strand at 2440.579 kb on + strand at 2440.579 kb on + strand at 2440.579 kb on + strand at 2440.580 kb on - strand at 2440.580 kb on - strand at 2440.580 kb on - strand at 2440.580 kb on - strand at 2440.580 kb on - strand at 2440.580 kb on - strand at 2440.580 kb on - strand at 2440.583 kb on - strand at 2440.583 kb on - strand at 2440.589 kb on + strand at 2440.589 kb on + strand at 2440.590 kb on - strand at 2440.590 kb on - strand at 2440.595 kb on + strand at 2440.595 kb on + strand at 2440.595 kb on + strand at 2440.595 kb on + strand at 2440.595 kb on + strand at 2440.596 kb on - strand at 2440.596 kb on - strand at 2440.596 kb on - strand at 2440.598 kb on + strand at 2440.598 kb on + strand at 2440.599 kb on - strand at 2440.599 kb on - strand at 2440.599 kb on - strand at 2440.603 kb on - strand at 2440.638 kb on - strand at 2440.666 kb on + strand at 2440.776 kb on + strand at 2440.776 kb on + strand at 2440.777 kb on - strand at 2440.827 kb on - strand at 2440.853 kb on - strand at 2440.871 kb on + strand at 2440.871 kb on + strand at 2440.872 kb on - strand at 2440.872 kb on - strand at 2440.872 kb on - strand at 2440.872 kb on - strand at 2441.010 kb on - strand at 2441.012 kb on + strand at 2441.012 kb on + strand at 2441.012 kb on + strand at 2441.012 kb on + strand at 2441.012 kb on + strand at 2441.012 kb on + strand at 2441.012 kb on + strand at 2441.012 kb on + strand at 2441.013 kb on - strand at 2441.013 kb on - strand at 2441.013 kb on - strand at 2441.013 kb on - strand at 2441.013 kb on - strand at 2441.013 kb on - strand at 2441.013 kb on - strand at 2441.013 kb on - strand at 2441.018 kb on + strand at 2441.018 kb on + strand at 2441.018 kb on + strand at 2441.019 kb on - strand at 2441.019 kb on - strand at 2441.019 kb on - strand at 2441.082 kb on + strand at 2441.082 kb on + strand at 2441.082 kb on + strand at 2441.082 kb on + strand at 2441.082 kb on + strand at 2441.082 kb on + strand at 2441.082 kb on + strand at 2441.082 kb on + strand at 2441.082 kb on + strand at 2441.082 kb on + strand at 2441.082 kb on + strand at 2441.082 kb on + strand at 2441.082 kb on + strand at 2441.082 kb on + strand at 2441.082 kb on + strand at 2441.083 kb on - strand at 2441.083 kb on - strand at 2441.083 kb on - strand at 2441.083 kb on - strand at 2441.083 kb on - strand at 2441.083 kb on - strand at 2441.112 kb on - strand at 2441.117 kb on - strand at 2441.117 kb on - strand at 2441.146 kb on + strand at 2441.146 kb on + strand at 2441.146 kb on + strand at 2441.146 kb on + strand at 2441.147 kb on - strand at 2441.147 kb on - strand at 2441.227 kb on - strand, within PfGW456L13_2223 at 2441.227 kb on - strand, within PfGW456L13_2223 at 2441.227 kb on - strand, within PfGW456L13_2223 at 2441.235 kb on + strand, within PfGW456L13_2223 at 2441.235 kb on + strand, within PfGW456L13_2223 at 2441.235 kb on + strand, within PfGW456L13_2223 at 2441.235 kb on + strand, within PfGW456L13_2223 at 2441.235 kb on + strand, within PfGW456L13_2223 at 2441.235 kb on + strand, within PfGW456L13_2223 at 2441.235 kb on + strand, within PfGW456L13_2223 at 2441.235 kb on + strand, within PfGW456L13_2223 at 2441.235 kb on + strand, within PfGW456L13_2223 at 2441.235 kb on + strand, within PfGW456L13_2223 at 2441.235 kb on + strand, within PfGW456L13_2223 at 2441.235 kb on + strand, within PfGW456L13_2223 at 2441.235 kb on + strand, within PfGW456L13_2223 at 2441.235 kb on + strand, within PfGW456L13_2223 at 2441.235 kb on + strand at 2441.236 kb on - strand, within PfGW456L13_2223 at 2441.236 kb on - strand, within PfGW456L13_2223 at 2441.236 kb on - strand, within PfGW456L13_2223 at 2441.236 kb on - strand, within PfGW456L13_2223 at 2441.236 kb on - strand, within PfGW456L13_2223 at 2441.238 kb on - strand, within PfGW456L13_2223 at 2441.238 kb on - strand, within PfGW456L13_2223 at 2441.264 kb on + strand, within PfGW456L13_2223 at 2441.264 kb on + strand, within PfGW456L13_2223 at 2441.264 kb on + strand, within PfGW456L13_2223 at 2441.264 kb on + strand, within PfGW456L13_2223 at 2441.264 kb on + strand, within PfGW456L13_2223 at 2441.265 kb on - strand, within PfGW456L13_2223 at 2441.265 kb on - strand, within PfGW456L13_2223 at 2441.268 kb on + strand, within PfGW456L13_2223 at 2441.268 kb on + strand, within PfGW456L13_2223 at 2441.268 kb on + strand, within PfGW456L13_2223 at 2441.269 kb on - strand, within PfGW456L13_2223 at 2441.269 kb on - strand, within PfGW456L13_2223 at 2441.269 kb on - strand, within PfGW456L13_2223 at 2441.269 kb on - strand, within PfGW456L13_2223 at 2441.269 kb on - strand, within PfGW456L13_2223 at 2441.340 kb on + strand, within PfGW456L13_2223 at 2441.340 kb on + strand, within PfGW456L13_2223 at 2441.340 kb on + strand, within PfGW456L13_2223 at 2441.358 kb on + strand, within PfGW456L13_2223 at 2441.359 kb on - strand, within PfGW456L13_2223 at 2441.359 kb on - strand, within PfGW456L13_2223 at 2441.382 kb on + strand, within PfGW456L13_2223 at 2441.382 kb on + strand, within PfGW456L13_2223 at 2441.382 kb on + strand, within PfGW456L13_2223 at 2441.382 kb on + strand, within PfGW456L13_2223 at 2441.382 kb on + strand, within PfGW456L13_2223 at 2441.382 kb on + strand, within PfGW456L13_2223 at 2441.382 kb on + strand, within PfGW456L13_2223 at 2441.383 kb on - strand, within PfGW456L13_2223 at 2441.383 kb on - strand, within PfGW456L13_2223 at 2441.383 kb on - strand, within PfGW456L13_2223 at 2441.394 kb on + strand, within PfGW456L13_2223 at 2441.394 kb on + strand, within PfGW456L13_2223 at 2441.395 kb on - strand, within PfGW456L13_2223 at 2441.395 kb on - strand at 2441.395 kb on - strand, within PfGW456L13_2223 at 2441.459 kb on + strand at 2441.459 kb on + strand at 2441.459 kb on + strand at 2441.460 kb on - strand at 2441.543 kb on + strand at 2441.636 kb on - strand, within PfGW456L13_2224 at 2441.875 kb on + strand, within PfGW456L13_2224 at 2441.876 kb on - strand, within PfGW456L13_2224 at 2441.917 kb on + strand, within PfGW456L13_2224 at 2442.145 kb on + strand, within PfGW456L13_2224 at 2442.145 kb on + strand, within PfGW456L13_2224 at 2442.145 kb on + strand, within PfGW456L13_2224 at 2442.266 kb on - strand, within PfGW456L13_2224 at 2442.302 kb on + strand, within PfGW456L13_2224 at 2442.302 kb on + strand, within PfGW456L13_2224 at 2442.302 kb on + strand, within PfGW456L13_2224 at 2442.303 kb on - strand, within PfGW456L13_2224 at 2442.303 kb on - strand, within PfGW456L13_2224 at 2442.303 kb on - strand, within PfGW456L13_2224 at 2442.303 kb on - strand, within PfGW456L13_2224 at 2442.320 kb on - strand, within PfGW456L13_2224 at 2442.320 kb on - strand, within PfGW456L13_2224 at 2442.330 kb on - strand, within PfGW456L13_2224 at 2442.337 kb on + strand, within PfGW456L13_2224 at 2442.338 kb on - strand, within PfGW456L13_2224 at 2442.338 kb on - strand, within PfGW456L13_2224 at 2442.338 kb on - strand, within PfGW456L13_2224 at 2442.338 kb on - strand, within PfGW456L13_2224 at 2442.385 kb on + strand, within PfGW456L13_2224 at 2442.386 kb on - strand, within PfGW456L13_2224 at 2442.525 kb on - strand at 2442.576 kb on + strand at 2442.667 kb on - strand at 2442.792 kb on - strand at 2442.923 kb on + strand, within PfGW456L13_2225 at 2442.997 kb on + strand, within PfGW456L13_2225 at 2442.997 kb on + strand, within PfGW456L13_2225 at 2443.037 kb on + strand, within PfGW456L13_2225 at 2443.038 kb on - strand, within PfGW456L13_2225 at 2443.038 kb on - strand, within PfGW456L13_2225 at 2443.047 kb on - strand at 2443.078 kb on + strand at 2443.078 kb on + strand at 2443.078 kb on + strand at 2443.078 kb on + strand at 2443.079 kb on - strand at 2443.115 kb on + strand at 2443.143 kb on + strand at 2443.144 kb on - strand at 2443.144 kb on - strand at 2443.144 kb on - strand at 2443.144 kb on - strand at 2443.189 kb on + strand at 2443.190 kb on - strand at 2443.279 kb on + strand at 2443.279 kb on + strand at 2443.280 kb on - strand at 2443.280 kb on - strand at 2443.280 kb on - strand at 2443.280 kb on - strand at 2443.281 kb on + strand at 2443.281 kb on + strand at 2443.281 kb on + strand at 2443.281 kb on + strand at 2443.282 kb on - strand at 2443.282 kb on - strand at 2443.282 kb on - strand at 2443.282 kb on - strand at 2443.282 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.125 mg/ml remove 2,440,534 + -0.8 2,440,535 - +0.9 2,440,535 - -0.1 2,440,535 - -0.1 2,440,537 + +3.1 2,440,538 - +0.5 2,440,538 - -0.1 2,440,538 - +0.3 2,440,541 + -0.4 2,440,541 + -1.1 2,440,541 + -0.4 2,440,541 + +0.0 2,440,541 + -1.9 2,440,542 - +0.5 2,440,542 - +1.0 2,440,542 - +0.2 2,440,542 - +0.4 2,440,542 - +0.8 2,440,542 - +0.6 2,440,542 - -0.1 2,440,545 + -0.6 2,440,545 + +0.8 2,440,545 + +0.3 2,440,545 + -0.3 2,440,545 + +1.2 2,440,546 - +0.3 2,440,546 - -0.4 2,440,546 - -0.3 2,440,546 - +0.2 2,440,546 - +0.6 2,440,546 - -0.0 2,440,575 + -0.3 2,440,575 + +1.8 2,440,576 - -2.2 2,440,576 - +0.5 2,440,579 + +0.6 2,440,579 + +0.2 2,440,579 + -0.7 2,440,579 + +1.0 2,440,579 + -0.7 2,440,579 + +0.1 2,440,580 - +0.6 2,440,580 - +0.2 2,440,580 - +0.2 2,440,580 - +0.6 2,440,580 - +1.1 2,440,580 - +0.9 2,440,580 - +0.8 2,440,583 - +0.7 2,440,583 - +1.4 2,440,589 + -1.4 2,440,589 + -0.4 2,440,590 - +0.9 2,440,590 - -0.6 2,440,595 + -0.2 2,440,595 + +0.4 2,440,595 + -0.4 2,440,595 + +0.6 2,440,595 + +0.2 2,440,596 - -1.2 2,440,596 - -2.1 2,440,596 - -0.4 2,440,598 + -0.7 2,440,598 + -0.5 2,440,599 - -1.2 2,440,599 - +0.1 2,440,599 - +0.3 2,440,603 - -0.1 2,440,638 - +0.7 2,440,666 + -1.6 2,440,776 + -0.9 2,440,776 + +0.5 2,440,777 - +0.5 2,440,827 - +0.2 2,440,853 - -1.0 2,440,871 + -0.1 2,440,871 + -0.4 2,440,872 - -0.5 2,440,872 - -0.5 2,440,872 - +2.6 2,440,872 - +0.4 2,441,010 - -0.5 2,441,012 + -0.1 2,441,012 + +0.5 2,441,012 + +0.6 2,441,012 + +0.4 2,441,012 + +0.5 2,441,012 + +0.8 2,441,012 + -0.7 2,441,012 + +1.3 2,441,013 - +0.3 2,441,013 - -0.3 2,441,013 - +0.8 2,441,013 - -0.0 2,441,013 - +0.8 2,441,013 - -0.2 2,441,013 - +0.2 2,441,013 - +0.3 2,441,018 + +1.0 2,441,018 + +0.3 2,441,018 + -0.4 2,441,019 - +0.1 2,441,019 - +0.3 2,441,019 - -0.1 2,441,082 + +0.1 2,441,082 + +0.4 2,441,082 + -0.3 2,441,082 + +0.2 2,441,082 + -0.2 2,441,082 + +0.2 2,441,082 + +0.4 2,441,082 + +0.1 2,441,082 + +0.2 2,441,082 + +0.4 2,441,082 + +0.3 2,441,082 + +0.3 2,441,082 + +0.6 2,441,082 + -0.3 2,441,082 + +0.0 2,441,083 - +0.5 2,441,083 - -0.6 2,441,083 - +0.4 2,441,083 - -1.4 2,441,083 - -0.6 2,441,083 - -0.7 2,441,112 - +0.4 2,441,117 - -0.3 2,441,117 - +1.2 2,441,146 + +1.0 2,441,146 + -0.2 2,441,146 + +0.1 2,441,146 + -0.6 2,441,147 - -0.8 2,441,147 - -0.3 2,441,227 - PfGW456L13_2223 0.26 +0.6 2,441,227 - PfGW456L13_2223 0.26 -1.4 2,441,227 - PfGW456L13_2223 0.26 -0.6 2,441,235 + PfGW456L13_2223 0.29 +0.7 2,441,235 + PfGW456L13_2223 0.29 -1.4 2,441,235 + PfGW456L13_2223 0.29 -0.1 2,441,235 + PfGW456L13_2223 0.29 +0.1 2,441,235 + PfGW456L13_2223 0.29 -1.2 2,441,235 + PfGW456L13_2223 0.29 +0.4 2,441,235 + PfGW456L13_2223 0.29 +1.1 2,441,235 + PfGW456L13_2223 0.29 -0.7 2,441,235 + PfGW456L13_2223 0.29 +0.8 2,441,235 + PfGW456L13_2223 0.29 -0.4 2,441,235 + PfGW456L13_2223 0.29 +0.1 2,441,235 + PfGW456L13_2223 0.29 +0.2 2,441,235 + PfGW456L13_2223 0.29 -0.7 2,441,235 + PfGW456L13_2223 0.29 -0.6 2,441,235 + +1.6 2,441,236 - PfGW456L13_2223 0.30 +0.2 2,441,236 - PfGW456L13_2223 0.30 -0.6 2,441,236 - PfGW456L13_2223 0.30 +0.8 2,441,236 - PfGW456L13_2223 0.30 +0.1 2,441,236 - PfGW456L13_2223 0.30 -0.4 2,441,238 - PfGW456L13_2223 0.30 +0.2 2,441,238 - PfGW456L13_2223 0.30 +0.6 2,441,264 + PfGW456L13_2223 0.39 +0.0 2,441,264 + PfGW456L13_2223 0.39 +1.2 2,441,264 + PfGW456L13_2223 0.39 +1.5 2,441,264 + PfGW456L13_2223 0.39 +0.3 2,441,264 + PfGW456L13_2223 0.39 -0.2 2,441,265 - PfGW456L13_2223 0.40 +0.5 2,441,265 - PfGW456L13_2223 0.40 -1.1 2,441,268 + PfGW456L13_2223 0.41 -0.4 2,441,268 + PfGW456L13_2223 0.41 +1.1 2,441,268 + PfGW456L13_2223 0.41 -0.6 2,441,269 - PfGW456L13_2223 0.41 +1.4 2,441,269 - PfGW456L13_2223 0.41 +1.0 2,441,269 - PfGW456L13_2223 0.41 -0.7 2,441,269 - PfGW456L13_2223 0.41 -0.4 2,441,269 - PfGW456L13_2223 0.41 +0.2 2,441,340 + PfGW456L13_2223 0.66 -0.3 2,441,340 + PfGW456L13_2223 0.66 +0.6 2,441,340 + PfGW456L13_2223 0.66 -1.0 2,441,358 + PfGW456L13_2223 0.72 +0.2 2,441,359 - PfGW456L13_2223 0.72 +0.2 2,441,359 - PfGW456L13_2223 0.72 -0.4 2,441,382 + PfGW456L13_2223 0.80 +1.3 2,441,382 + PfGW456L13_2223 0.80 -1.3 2,441,382 + PfGW456L13_2223 0.80 +0.0 2,441,382 + PfGW456L13_2223 0.80 +1.0 2,441,382 + PfGW456L13_2223 0.80 +1.0 2,441,382 + PfGW456L13_2223 0.80 +1.1 2,441,382 + PfGW456L13_2223 0.80 +0.8 2,441,383 - PfGW456L13_2223 0.81 -0.7 2,441,383 - PfGW456L13_2223 0.81 -2.8 2,441,383 - PfGW456L13_2223 0.81 -1.5 2,441,394 + PfGW456L13_2223 0.84 +0.9 2,441,394 + PfGW456L13_2223 0.84 +0.5 2,441,395 - PfGW456L13_2223 0.85 -0.6 2,441,395 - -1.7 2,441,395 - PfGW456L13_2223 0.85 +0.3 2,441,459 + +0.1 2,441,459 + +1.4 2,441,459 + +1.6 2,441,460 - -0.5 2,441,543 + +0.1 2,441,636 - PfGW456L13_2224 0.10 -1.8 2,441,875 + PfGW456L13_2224 0.32 +0.2 2,441,876 - PfGW456L13_2224 0.32 -0.4 2,441,917 + PfGW456L13_2224 0.36 +0.9 2,442,145 + PfGW456L13_2224 0.57 -0.8 2,442,145 + PfGW456L13_2224 0.57 -0.4 2,442,145 + PfGW456L13_2224 0.57 +1.4 2,442,266 - PfGW456L13_2224 0.69 -0.9 2,442,302 + PfGW456L13_2224 0.72 -0.4 2,442,302 + PfGW456L13_2224 0.72 -0.7 2,442,302 + PfGW456L13_2224 0.72 -0.7 2,442,303 - PfGW456L13_2224 0.72 -0.0 2,442,303 - PfGW456L13_2224 0.72 -1.5 2,442,303 - PfGW456L13_2224 0.72 -0.6 2,442,303 - PfGW456L13_2224 0.72 -0.5 2,442,320 - PfGW456L13_2224 0.74 +0.6 2,442,320 - PfGW456L13_2224 0.74 -0.2 2,442,330 - PfGW456L13_2224 0.75 -0.2 2,442,337 + PfGW456L13_2224 0.75 -0.7 2,442,338 - PfGW456L13_2224 0.75 -2.0 2,442,338 - PfGW456L13_2224 0.75 -1.5 2,442,338 - PfGW456L13_2224 0.75 -1.9 2,442,338 - PfGW456L13_2224 0.75 -0.8 2,442,385 + PfGW456L13_2224 0.80 +0.4 2,442,386 - PfGW456L13_2224 0.80 -0.1 2,442,525 - +0.4 2,442,576 + +0.3 2,442,667 - +0.1 2,442,792 - +1.1 2,442,923 + PfGW456L13_2225 0.47 +2.6 2,442,997 + PfGW456L13_2225 0.73 +0.7 2,442,997 + PfGW456L13_2225 0.73 -0.1 2,443,037 + PfGW456L13_2225 0.87 -0.5 2,443,038 - PfGW456L13_2225 0.87 +1.6 2,443,038 - PfGW456L13_2225 0.87 +0.5 2,443,047 - -0.1 2,443,078 + +0.2 2,443,078 + +0.5 2,443,078 + -0.2 2,443,078 + -0.1 2,443,079 - +0.3 2,443,115 + -0.2 2,443,143 + -0.3 2,443,144 - -0.2 2,443,144 - -0.6 2,443,144 - +1.2 2,443,144 - -0.2 2,443,189 + -1.2 2,443,190 - -1.4 2,443,279 + +0.6 2,443,279 + +0.8 2,443,280 - +0.1 2,443,280 - -0.0 2,443,280 - -2.7 2,443,280 - +1.6 2,443,281 + -0.3 2,443,281 + +0.4 2,443,281 + -1.0 2,443,281 + +0.1 2,443,282 - +1.3 2,443,282 - +0.6 2,443,282 - -0.5 2,443,282 - +0.5 2,443,282 - -1.0
Or see this region's nucleotide sequence