Experiment: Vancomycin 0.125 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_2148 and PfGW456L13_2149 are separated by 64 nucleotides PfGW456L13_2149 and PfGW456L13_2150 are separated by 154 nucleotides PfGW456L13_2150 and PfGW456L13_2151 are separated by 5 nucleotides PfGW456L13_2151 and PfGW456L13_2152 are separated by 201 nucleotides
PfGW456L13_2148 - Oxidoreductase, short chain dehydrogenase/reductase family, at 2,350,267 to 2,351,082
_2148
PfGW456L13_2149 - Protein of unknown function UPF0060, at 2,351,147 to 2,351,479
_2149
PfGW456L13_2150 - Carbon storage regulator, at 2,351,634 to 2,351,819
_2150
PfGW456L13_2151 - FIG00953242: hypothetical protein, at 2,351,825 to 2,352,052
_2151
PfGW456L13_2152 - Deblocking aminopeptidase (EC 3.4.11.-) @ Cyanophycinase 2 (EC 3.4.15.6), at 2,352,254 to 2,353,444
_2152
Position (kb)
2351
2352 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 2350.714 kb on + strand, within PfGW456L13_2148 at 2350.714 kb on + strand, within PfGW456L13_2148 at 2350.714 kb on + strand, within PfGW456L13_2148 at 2350.714 kb on + strand, within PfGW456L13_2148 at 2350.715 kb on - strand, within PfGW456L13_2148 at 2350.715 kb on - strand, within PfGW456L13_2148 at 2350.715 kb on - strand at 2350.715 kb on - strand, within PfGW456L13_2148 at 2350.715 kb on - strand, within PfGW456L13_2148 at 2350.715 kb on - strand, within PfGW456L13_2148 at 2350.715 kb on - strand, within PfGW456L13_2148 at 2350.715 kb on - strand, within PfGW456L13_2148 at 2350.921 kb on + strand, within PfGW456L13_2148 at 2350.921 kb on + strand, within PfGW456L13_2148 at 2350.921 kb on + strand, within PfGW456L13_2148 at 2350.921 kb on + strand, within PfGW456L13_2148 at 2350.922 kb on - strand, within PfGW456L13_2148 at 2350.922 kb on - strand, within PfGW456L13_2148 at 2350.922 kb on - strand, within PfGW456L13_2148 at 2350.922 kb on - strand, within PfGW456L13_2148 at 2350.922 kb on - strand, within PfGW456L13_2148 at 2350.922 kb on - strand, within PfGW456L13_2148 at 2350.927 kb on + strand, within PfGW456L13_2148 at 2350.927 kb on + strand, within PfGW456L13_2148 at 2350.927 kb on + strand, within PfGW456L13_2148 at 2350.927 kb on + strand, within PfGW456L13_2148 at 2350.928 kb on - strand, within PfGW456L13_2148 at 2350.928 kb on - strand, within PfGW456L13_2148 at 2350.928 kb on - strand, within PfGW456L13_2148 at 2350.928 kb on - strand, within PfGW456L13_2148 at 2350.928 kb on - strand, within PfGW456L13_2148 at 2350.928 kb on - strand, within PfGW456L13_2148 at 2350.928 kb on - strand, within PfGW456L13_2148 at 2350.928 kb on - strand, within PfGW456L13_2148 at 2350.928 kb on - strand, within PfGW456L13_2148 at 2351.020 kb on + strand at 2351.152 kb on + strand at 2351.152 kb on + strand at 2351.152 kb on + strand at 2351.152 kb on + strand at 2351.152 kb on + strand at 2351.152 kb on + strand at 2351.152 kb on + strand at 2351.152 kb on + strand at 2351.153 kb on - strand at 2351.153 kb on - strand at 2351.153 kb on - strand at 2351.153 kb on - strand at 2351.153 kb on - strand at 2351.153 kb on - strand at 2351.153 kb on - strand at 2351.156 kb on + strand at 2351.156 kb on + strand at 2351.156 kb on + strand at 2351.156 kb on + strand at 2351.157 kb on - strand at 2351.157 kb on - strand at 2351.157 kb on - strand at 2351.157 kb on - strand at 2351.157 kb on - strand at 2351.157 kb on - strand at 2351.157 kb on - strand at 2351.157 kb on - strand at 2351.230 kb on + strand, within PfGW456L13_2149 at 2351.231 kb on - strand, within PfGW456L13_2149 at 2351.309 kb on + strand, within PfGW456L13_2149 at 2351.309 kb on + strand, within PfGW456L13_2149 at 2351.309 kb on + strand, within PfGW456L13_2149 at 2351.345 kb on + strand, within PfGW456L13_2149 at 2351.345 kb on + strand, within PfGW456L13_2149 at 2351.345 kb on + strand, within PfGW456L13_2149 at 2351.345 kb on + strand, within PfGW456L13_2149 at 2351.345 kb on + strand, within PfGW456L13_2149 at 2351.345 kb on + strand, within PfGW456L13_2149 at 2351.345 kb on + strand, within PfGW456L13_2149 at 2351.345 kb on + strand, within PfGW456L13_2149 at 2351.345 kb on + strand, within PfGW456L13_2149 at 2351.345 kb on + strand, within PfGW456L13_2149 at 2351.345 kb on + strand, within PfGW456L13_2149 at 2351.345 kb on + strand, within PfGW456L13_2149 at 2351.345 kb on + strand, within PfGW456L13_2149 at 2351.345 kb on + strand, within PfGW456L13_2149 at 2351.345 kb on + strand, within PfGW456L13_2149 at 2351.346 kb on - strand, within PfGW456L13_2149 at 2351.346 kb on - strand, within PfGW456L13_2149 at 2351.346 kb on - strand, within PfGW456L13_2149 at 2351.346 kb on - strand, within PfGW456L13_2149 at 2351.346 kb on - strand, within PfGW456L13_2149 at 2351.491 kb on + strand at 2351.492 kb on - strand at 2351.492 kb on - strand at 2351.492 kb on - strand at 2351.521 kb on + strand at 2351.521 kb on + strand at 2351.522 kb on - strand at 2351.576 kb on + strand at 2351.576 kb on + strand at 2351.576 kb on + strand at 2351.576 kb on + strand at 2351.576 kb on + strand at 2351.576 kb on + strand at 2351.577 kb on - strand at 2351.577 kb on - strand at 2351.577 kb on - strand at 2351.577 kb on - strand at 2351.641 kb on + strand at 2351.641 kb on + strand at 2351.641 kb on + strand at 2351.642 kb on - strand at 2351.642 kb on - strand at 2351.642 kb on - strand at 2351.775 kb on + strand, within PfGW456L13_2150 at 2351.776 kb on - strand, within PfGW456L13_2150 at 2351.776 kb on - strand, within PfGW456L13_2150 at 2352.052 kb on + strand at 2352.052 kb on + strand at 2352.053 kb on - strand at 2352.053 kb on - strand at 2352.228 kb on + strand at 2352.228 kb on + strand at 2352.228 kb on + strand at 2352.230 kb on + strand at 2352.230 kb on + strand at 2352.230 kb on + strand at 2352.230 kb on + strand at 2352.231 kb on - strand at 2352.231 kb on - strand at 2352.231 kb on - strand at 2352.231 kb on - strand at 2352.231 kb on - strand at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.408 kb on + strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.409 kb on - strand, within PfGW456L13_2152 at 2352.549 kb on + strand, within PfGW456L13_2152 at 2352.550 kb on - strand, within PfGW456L13_2152 at 2352.552 kb on + strand, within PfGW456L13_2152 at 2352.553 kb on - strand, within PfGW456L13_2152 at 2352.624 kb on + strand, within PfGW456L13_2152 at 2352.624 kb on + strand, within PfGW456L13_2152 at 2352.624 kb on + strand, within PfGW456L13_2152 at 2352.624 kb on + strand, within PfGW456L13_2152 at 2352.624 kb on + strand, within PfGW456L13_2152 at 2352.625 kb on - strand, within PfGW456L13_2152 at 2352.625 kb on - strand, within PfGW456L13_2152 at 2352.625 kb on - strand, within PfGW456L13_2152
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.125 mg/ml remove 2,350,714 + PfGW456L13_2148 0.55 +1.2 2,350,714 + PfGW456L13_2148 0.55 +0.8 2,350,714 + PfGW456L13_2148 0.55 -0.2 2,350,714 + PfGW456L13_2148 0.55 -1.6 2,350,715 - PfGW456L13_2148 0.55 -0.6 2,350,715 - PfGW456L13_2148 0.55 -0.6 2,350,715 - +0.7 2,350,715 - PfGW456L13_2148 0.55 +0.9 2,350,715 - PfGW456L13_2148 0.55 +0.7 2,350,715 - PfGW456L13_2148 0.55 -0.1 2,350,715 - PfGW456L13_2148 0.55 -0.7 2,350,715 - PfGW456L13_2148 0.55 -1.3 2,350,921 + PfGW456L13_2148 0.80 +0.5 2,350,921 + PfGW456L13_2148 0.80 -2.4 2,350,921 + PfGW456L13_2148 0.80 -0.0 2,350,921 + PfGW456L13_2148 0.80 -2.7 2,350,922 - PfGW456L13_2148 0.80 +0.0 2,350,922 - PfGW456L13_2148 0.80 -1.3 2,350,922 - PfGW456L13_2148 0.80 -0.5 2,350,922 - PfGW456L13_2148 0.80 +0.7 2,350,922 - PfGW456L13_2148 0.80 -0.6 2,350,922 - PfGW456L13_2148 0.80 -0.1 2,350,927 + PfGW456L13_2148 0.81 +0.8 2,350,927 + PfGW456L13_2148 0.81 +0.3 2,350,927 + PfGW456L13_2148 0.81 +0.2 2,350,927 + PfGW456L13_2148 0.81 +0.3 2,350,928 - PfGW456L13_2148 0.81 +0.1 2,350,928 - PfGW456L13_2148 0.81 -0.1 2,350,928 - PfGW456L13_2148 0.81 -0.0 2,350,928 - PfGW456L13_2148 0.81 +0.2 2,350,928 - PfGW456L13_2148 0.81 -0.1 2,350,928 - PfGW456L13_2148 0.81 +0.7 2,350,928 - PfGW456L13_2148 0.81 +0.2 2,350,928 - PfGW456L13_2148 0.81 -0.7 2,350,928 - PfGW456L13_2148 0.81 -0.6 2,351,020 + -0.9 2,351,152 + +0.5 2,351,152 + -1.8 2,351,152 + -0.9 2,351,152 + -1.7 2,351,152 + +0.4 2,351,152 + +0.4 2,351,152 + +0.6 2,351,152 + -1.0 2,351,153 - +0.0 2,351,153 - +1.6 2,351,153 - -0.4 2,351,153 - -0.1 2,351,153 - +0.7 2,351,153 - -0.3 2,351,153 - -0.0 2,351,156 + -0.8 2,351,156 + -0.4 2,351,156 + -0.1 2,351,156 + +0.0 2,351,157 - -0.8 2,351,157 - -1.4 2,351,157 - +0.4 2,351,157 - +0.8 2,351,157 - -0.3 2,351,157 - +0.5 2,351,157 - +1.0 2,351,157 - +0.1 2,351,230 + PfGW456L13_2149 0.25 -0.2 2,351,231 - PfGW456L13_2149 0.25 +0.6 2,351,309 + PfGW456L13_2149 0.49 +0.4 2,351,309 + PfGW456L13_2149 0.49 -0.6 2,351,309 + PfGW456L13_2149 0.49 -1.5 2,351,345 + PfGW456L13_2149 0.59 -0.5 2,351,345 + PfGW456L13_2149 0.59 -0.8 2,351,345 + PfGW456L13_2149 0.59 +0.5 2,351,345 + PfGW456L13_2149 0.59 -0.6 2,351,345 + PfGW456L13_2149 0.59 +0.1 2,351,345 + PfGW456L13_2149 0.59 +0.8 2,351,345 + PfGW456L13_2149 0.59 -0.6 2,351,345 + PfGW456L13_2149 0.59 -0.1 2,351,345 + PfGW456L13_2149 0.59 +0.3 2,351,345 + PfGW456L13_2149 0.59 -0.7 2,351,345 + PfGW456L13_2149 0.59 -0.9 2,351,345 + PfGW456L13_2149 0.59 +0.2 2,351,345 + PfGW456L13_2149 0.59 +0.6 2,351,345 + PfGW456L13_2149 0.59 -1.1 2,351,345 + PfGW456L13_2149 0.59 -0.4 2,351,346 - PfGW456L13_2149 0.60 +0.2 2,351,346 - PfGW456L13_2149 0.60 +0.9 2,351,346 - PfGW456L13_2149 0.60 +0.6 2,351,346 - PfGW456L13_2149 0.60 -0.4 2,351,346 - PfGW456L13_2149 0.60 +0.7 2,351,491 + +0.2 2,351,492 - +0.0 2,351,492 - -1.9 2,351,492 - -0.9 2,351,521 + -0.0 2,351,521 + -1.9 2,351,522 - +1.2 2,351,576 + -0.0 2,351,576 + +0.4 2,351,576 + +0.4 2,351,576 + +0.6 2,351,576 + +1.0 2,351,576 + -0.0 2,351,577 - +0.6 2,351,577 - +0.2 2,351,577 - +1.2 2,351,577 - -0.4 2,351,641 + -2.1 2,351,641 + +0.6 2,351,641 + -0.7 2,351,642 - -0.5 2,351,642 - +0.1 2,351,642 - -1.0 2,351,775 + PfGW456L13_2150 0.76 -0.9 2,351,776 - PfGW456L13_2150 0.76 -0.7 2,351,776 - PfGW456L13_2150 0.76 -1.6 2,352,052 + +0.3 2,352,052 + -1.4 2,352,053 - +0.8 2,352,053 - +0.0 2,352,228 + +0.4 2,352,228 + +1.0 2,352,228 + -0.4 2,352,230 + -0.5 2,352,230 + +1.3 2,352,230 + +0.0 2,352,230 + -0.3 2,352,231 - +1.0 2,352,231 - -1.0 2,352,231 - +0.3 2,352,231 - +0.7 2,352,231 - +1.4 2,352,408 + PfGW456L13_2152 0.13 +0.4 2,352,408 + PfGW456L13_2152 0.13 +0.3 2,352,408 + PfGW456L13_2152 0.13 -1.3 2,352,408 + PfGW456L13_2152 0.13 -0.0 2,352,408 + PfGW456L13_2152 0.13 -0.3 2,352,408 + PfGW456L13_2152 0.13 +1.5 2,352,408 + PfGW456L13_2152 0.13 +2.2 2,352,408 + PfGW456L13_2152 0.13 -0.7 2,352,408 + PfGW456L13_2152 0.13 -1.7 2,352,408 + PfGW456L13_2152 0.13 +1.0 2,352,408 + PfGW456L13_2152 0.13 +1.3 2,352,408 + PfGW456L13_2152 0.13 -0.3 2,352,408 + PfGW456L13_2152 0.13 +1.1 2,352,408 + PfGW456L13_2152 0.13 +1.5 2,352,408 + PfGW456L13_2152 0.13 -0.4 2,352,408 + PfGW456L13_2152 0.13 -0.4 2,352,408 + PfGW456L13_2152 0.13 -0.0 2,352,408 + PfGW456L13_2152 0.13 +0.3 2,352,408 + PfGW456L13_2152 0.13 -0.4 2,352,408 + PfGW456L13_2152 0.13 -0.1 2,352,408 + PfGW456L13_2152 0.13 +0.8 2,352,408 + -0.3 2,352,408 + PfGW456L13_2152 0.13 -0.2 2,352,408 + PfGW456L13_2152 0.13 +1.3 2,352,408 + PfGW456L13_2152 0.13 -0.3 2,352,408 + PfGW456L13_2152 0.13 -0.3 2,352,408 + PfGW456L13_2152 0.13 +0.6 2,352,408 + PfGW456L13_2152 0.13 -0.2 2,352,409 - PfGW456L13_2152 0.13 +0.1 2,352,409 - PfGW456L13_2152 0.13 +0.4 2,352,409 - PfGW456L13_2152 0.13 +0.1 2,352,409 - PfGW456L13_2152 0.13 -0.4 2,352,409 - PfGW456L13_2152 0.13 -0.4 2,352,409 - PfGW456L13_2152 0.13 +1.7 2,352,409 - PfGW456L13_2152 0.13 -0.6 2,352,409 - PfGW456L13_2152 0.13 -0.5 2,352,409 - PfGW456L13_2152 0.13 -1.4 2,352,409 - PfGW456L13_2152 0.13 +0.1 2,352,409 - PfGW456L13_2152 0.13 -1.2 2,352,409 - PfGW456L13_2152 0.13 -0.0 2,352,409 - PfGW456L13_2152 0.13 +0.4 2,352,409 - PfGW456L13_2152 0.13 -1.0 2,352,409 - PfGW456L13_2152 0.13 -0.2 2,352,409 - PfGW456L13_2152 0.13 +0.9 2,352,409 - PfGW456L13_2152 0.13 +1.2 2,352,409 - PfGW456L13_2152 0.13 -0.4 2,352,409 - PfGW456L13_2152 0.13 -1.1 2,352,409 - PfGW456L13_2152 0.13 -0.6 2,352,409 - PfGW456L13_2152 0.13 -0.2 2,352,409 - PfGW456L13_2152 0.13 -1.1 2,352,409 - PfGW456L13_2152 0.13 -0.9 2,352,409 - PfGW456L13_2152 0.13 +0.5 2,352,409 - PfGW456L13_2152 0.13 +0.6 2,352,409 - PfGW456L13_2152 0.13 +0.5 2,352,409 - PfGW456L13_2152 0.13 -0.1 2,352,409 - PfGW456L13_2152 0.13 -0.2 2,352,409 - PfGW456L13_2152 0.13 +0.9 2,352,409 - PfGW456L13_2152 0.13 +0.4 2,352,409 - PfGW456L13_2152 0.13 +0.2 2,352,409 - PfGW456L13_2152 0.13 -1.6 2,352,409 - PfGW456L13_2152 0.13 -0.1 2,352,409 - PfGW456L13_2152 0.13 -0.6 2,352,409 - PfGW456L13_2152 0.13 +1.5 2,352,409 - PfGW456L13_2152 0.13 -0.9 2,352,409 - PfGW456L13_2152 0.13 -0.1 2,352,549 + PfGW456L13_2152 0.25 +0.4 2,352,550 - PfGW456L13_2152 0.25 +0.9 2,352,552 + PfGW456L13_2152 0.25 +0.1 2,352,553 - PfGW456L13_2152 0.25 +0.8 2,352,624 + PfGW456L13_2152 0.31 -0.3 2,352,624 + PfGW456L13_2152 0.31 -0.1 2,352,624 + PfGW456L13_2152 0.31 -0.2 2,352,624 + PfGW456L13_2152 0.31 -0.4 2,352,624 + PfGW456L13_2152 0.31 +0.3 2,352,625 - PfGW456L13_2152 0.31 -2.2 2,352,625 - PfGW456L13_2152 0.31 -1.8 2,352,625 - PfGW456L13_2152 0.31 +2.1
Or see this region's nucleotide sequence