Experiment: Vancomycin 0.125 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_2049 and PfGW456L13_2050 are separated by 32 nucleotides PfGW456L13_2050 and PfGW456L13_2051 are separated by 113 nucleotides PfGW456L13_2051 and PfGW456L13_2052 overlap by 4 nucleotides
PfGW456L13_2049 - Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3), at 2,252,171 to 2,253,838
_2049
PfGW456L13_2050 - FIG002571: 4-hydroxybenzoyl-CoA thioesterase domain protein, at 2,253,871 to 2,254,314
_2050
PfGW456L13_2051 - FIG00955363: hypothetical protein, at 2,254,428 to 2,255,234
_2051
PfGW456L13_2052 - hydrolase, alpha/beta fold family, at 2,255,231 to 2,256,085
_2052
Position (kb)
2253
2254
2255 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 2252.899 kb on + strand, within PfGW456L13_2049 at 2252.984 kb on + strand, within PfGW456L13_2049 at 2252.984 kb on + strand, within PfGW456L13_2049 at 2252.985 kb on - strand, within PfGW456L13_2049 at 2252.985 kb on - strand, within PfGW456L13_2049 at 2253.055 kb on + strand, within PfGW456L13_2049 at 2253.055 kb on + strand, within PfGW456L13_2049 at 2253.056 kb on - strand, within PfGW456L13_2049 at 2253.056 kb on - strand, within PfGW456L13_2049 at 2253.056 kb on - strand, within PfGW456L13_2049 at 2253.141 kb on - strand, within PfGW456L13_2049 at 2253.173 kb on + strand, within PfGW456L13_2049 at 2253.173 kb on + strand, within PfGW456L13_2049 at 2253.173 kb on + strand, within PfGW456L13_2049 at 2253.173 kb on + strand, within PfGW456L13_2049 at 2253.174 kb on - strand, within PfGW456L13_2049 at 2253.326 kb on + strand, within PfGW456L13_2049 at 2253.326 kb on + strand, within PfGW456L13_2049 at 2253.326 kb on + strand, within PfGW456L13_2049 at 2253.327 kb on - strand, within PfGW456L13_2049 at 2253.389 kb on - strand, within PfGW456L13_2049 at 2253.467 kb on + strand, within PfGW456L13_2049 at 2253.467 kb on + strand, within PfGW456L13_2049 at 2253.467 kb on + strand, within PfGW456L13_2049 at 2253.467 kb on + strand, within PfGW456L13_2049 at 2253.468 kb on - strand, within PfGW456L13_2049 at 2253.468 kb on - strand, within PfGW456L13_2049 at 2253.468 kb on - strand, within PfGW456L13_2049 at 2253.780 kb on - strand at 2254.084 kb on + strand, within PfGW456L13_2050 at 2254.084 kb on + strand, within PfGW456L13_2050 at 2254.085 kb on - strand, within PfGW456L13_2050 at 2254.085 kb on - strand, within PfGW456L13_2050 at 2254.085 kb on - strand, within PfGW456L13_2050 at 2254.085 kb on - strand, within PfGW456L13_2050 at 2254.325 kb on + strand at 2254.325 kb on + strand at 2254.325 kb on + strand at 2254.326 kb on - strand at 2254.326 kb on - strand at 2254.326 kb on - strand at 2254.326 kb on - strand at 2254.326 kb on - strand at 2254.360 kb on - strand at 2254.374 kb on - strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.397 kb on + strand at 2254.398 kb on - strand at 2254.398 kb on - strand at 2254.398 kb on - strand at 2254.398 kb on - strand at 2254.398 kb on - strand at 2254.398 kb on - strand at 2254.398 kb on - strand at 2254.427 kb on + strand at 2254.427 kb on + strand at 2254.427 kb on + strand at 2254.427 kb on + strand at 2254.428 kb on - strand at 2254.428 kb on - strand at 2254.428 kb on - strand at 2254.428 kb on - strand at 2254.428 kb on - strand at 2254.428 kb on - strand at 2254.575 kb on + strand, within PfGW456L13_2051 at 2254.575 kb on + strand, within PfGW456L13_2051 at 2254.575 kb on + strand, within PfGW456L13_2051 at 2254.576 kb on - strand, within PfGW456L13_2051 at 2254.753 kb on + strand, within PfGW456L13_2051 at 2254.753 kb on + strand, within PfGW456L13_2051 at 2254.753 kb on + strand, within PfGW456L13_2051 at 2254.753 kb on + strand, within PfGW456L13_2051 at 2254.806 kb on - strand, within PfGW456L13_2051 at 2254.806 kb on - strand, within PfGW456L13_2051 at 2254.806 kb on - strand, within PfGW456L13_2051 at 2254.854 kb on + strand, within PfGW456L13_2051 at 2254.855 kb on - strand, within PfGW456L13_2051 at 2254.855 kb on - strand, within PfGW456L13_2051 at 2254.855 kb on - strand, within PfGW456L13_2051 at 2254.855 kb on - strand, within PfGW456L13_2051 at 2254.855 kb on - strand, within PfGW456L13_2051 at 2254.908 kb on + strand, within PfGW456L13_2051 at 2254.908 kb on + strand, within PfGW456L13_2051 at 2254.908 kb on + strand, within PfGW456L13_2051 at 2254.908 kb on + strand, within PfGW456L13_2051 at 2254.909 kb on - strand, within PfGW456L13_2051 at 2254.909 kb on - strand, within PfGW456L13_2051 at 2254.909 kb on - strand, within PfGW456L13_2051 at 2254.909 kb on - strand, within PfGW456L13_2051 at 2254.979 kb on + strand, within PfGW456L13_2051 at 2254.979 kb on + strand, within PfGW456L13_2051 at 2254.979 kb on + strand, within PfGW456L13_2051 at 2254.980 kb on - strand, within PfGW456L13_2051 at 2254.980 kb on - strand, within PfGW456L13_2051 at 2254.980 kb on - strand, within PfGW456L13_2051 at 2254.980 kb on - strand, within PfGW456L13_2051 at 2254.983 kb on + strand, within PfGW456L13_2051 at 2254.983 kb on + strand, within PfGW456L13_2051 at 2254.984 kb on - strand, within PfGW456L13_2051 at 2254.984 kb on - strand, within PfGW456L13_2051 at 2254.994 kb on - strand, within PfGW456L13_2051 at 2255.047 kb on + strand, within PfGW456L13_2051 at 2255.177 kb on + strand at 2255.177 kb on + strand at 2255.177 kb on + strand at 2255.177 kb on + strand at 2255.178 kb on - strand at 2255.178 kb on - strand at 2255.196 kb on + strand at 2255.196 kb on + strand at 2255.196 kb on + strand at 2255.197 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.125 mg/ml remove 2,252,899 + PfGW456L13_2049 0.44 +0.1 2,252,984 + PfGW456L13_2049 0.49 +0.9 2,252,984 + PfGW456L13_2049 0.49 +0.0 2,252,985 - PfGW456L13_2049 0.49 +0.1 2,252,985 - PfGW456L13_2049 0.49 -0.2 2,253,055 + PfGW456L13_2049 0.53 +1.2 2,253,055 + PfGW456L13_2049 0.53 +0.6 2,253,056 - PfGW456L13_2049 0.53 -0.1 2,253,056 - PfGW456L13_2049 0.53 +0.6 2,253,056 - PfGW456L13_2049 0.53 +0.1 2,253,141 - PfGW456L13_2049 0.58 +1.8 2,253,173 + PfGW456L13_2049 0.60 -1.7 2,253,173 + PfGW456L13_2049 0.60 +0.1 2,253,173 + PfGW456L13_2049 0.60 -1.2 2,253,173 + PfGW456L13_2049 0.60 -0.7 2,253,174 - PfGW456L13_2049 0.60 -0.9 2,253,326 + PfGW456L13_2049 0.69 -0.7 2,253,326 + PfGW456L13_2049 0.69 +1.3 2,253,326 + PfGW456L13_2049 0.69 +0.6 2,253,327 - PfGW456L13_2049 0.69 +0.8 2,253,389 - PfGW456L13_2049 0.73 -0.7 2,253,467 + PfGW456L13_2049 0.78 -0.7 2,253,467 + PfGW456L13_2049 0.78 +1.1 2,253,467 + PfGW456L13_2049 0.78 +0.1 2,253,467 + PfGW456L13_2049 0.78 +0.2 2,253,468 - PfGW456L13_2049 0.78 +0.2 2,253,468 - PfGW456L13_2049 0.78 -0.1 2,253,468 - PfGW456L13_2049 0.78 +1.4 2,253,780 - +0.4 2,254,084 + PfGW456L13_2050 0.48 +0.0 2,254,084 + PfGW456L13_2050 0.48 -2.1 2,254,085 - PfGW456L13_2050 0.48 -0.6 2,254,085 - PfGW456L13_2050 0.48 -0.7 2,254,085 - PfGW456L13_2050 0.48 +0.0 2,254,085 - PfGW456L13_2050 0.48 -0.7 2,254,325 + +0.6 2,254,325 + -0.8 2,254,325 + -1.1 2,254,326 - +0.1 2,254,326 - +0.2 2,254,326 - -0.2 2,254,326 - +0.2 2,254,326 - +0.1 2,254,360 - -1.5 2,254,374 - -0.4 2,254,397 + +0.7 2,254,397 + +0.3 2,254,397 + -0.5 2,254,397 + -0.8 2,254,397 + -0.5 2,254,397 + -0.2 2,254,397 + +1.9 2,254,397 + +1.3 2,254,397 + -0.1 2,254,397 + +0.5 2,254,397 + +0.2 2,254,397 + +1.2 2,254,397 + +0.4 2,254,398 - -0.9 2,254,398 - -2.5 2,254,398 - -0.7 2,254,398 - +0.0 2,254,398 - +0.7 2,254,398 - -0.0 2,254,398 - +0.8 2,254,427 + -1.9 2,254,427 + -1.2 2,254,427 + +0.7 2,254,427 + +0.7 2,254,428 - -0.3 2,254,428 - -0.6 2,254,428 - +0.3 2,254,428 - -0.2 2,254,428 - +1.6 2,254,428 - -1.3 2,254,575 + PfGW456L13_2051 0.18 +1.3 2,254,575 + PfGW456L13_2051 0.18 -0.1 2,254,575 + PfGW456L13_2051 0.18 +0.0 2,254,576 - PfGW456L13_2051 0.18 -1.9 2,254,753 + PfGW456L13_2051 0.40 -0.1 2,254,753 + PfGW456L13_2051 0.40 +0.7 2,254,753 + PfGW456L13_2051 0.40 -0.5 2,254,753 + PfGW456L13_2051 0.40 +0.7 2,254,806 - PfGW456L13_2051 0.47 -0.7 2,254,806 - PfGW456L13_2051 0.47 +0.7 2,254,806 - PfGW456L13_2051 0.47 +0.7 2,254,854 + PfGW456L13_2051 0.53 +0.6 2,254,855 - PfGW456L13_2051 0.53 +0.6 2,254,855 - PfGW456L13_2051 0.53 -0.5 2,254,855 - PfGW456L13_2051 0.53 +0.8 2,254,855 - PfGW456L13_2051 0.53 -0.0 2,254,855 - PfGW456L13_2051 0.53 -0.6 2,254,908 + PfGW456L13_2051 0.59 +0.9 2,254,908 + PfGW456L13_2051 0.59 -0.5 2,254,908 + PfGW456L13_2051 0.59 +0.5 2,254,908 + PfGW456L13_2051 0.59 -0.3 2,254,909 - PfGW456L13_2051 0.60 +0.7 2,254,909 - PfGW456L13_2051 0.60 -0.8 2,254,909 - PfGW456L13_2051 0.60 +0.4 2,254,909 - PfGW456L13_2051 0.60 +1.8 2,254,979 + PfGW456L13_2051 0.68 -0.8 2,254,979 + PfGW456L13_2051 0.68 -1.2 2,254,979 + PfGW456L13_2051 0.68 -0.2 2,254,980 - PfGW456L13_2051 0.68 -0.6 2,254,980 - PfGW456L13_2051 0.68 +0.2 2,254,980 - PfGW456L13_2051 0.68 +0.7 2,254,980 - PfGW456L13_2051 0.68 +1.1 2,254,983 + PfGW456L13_2051 0.69 -0.7 2,254,983 + PfGW456L13_2051 0.69 +0.7 2,254,984 - PfGW456L13_2051 0.69 -1.0 2,254,984 - PfGW456L13_2051 0.69 +0.3 2,254,994 - PfGW456L13_2051 0.70 +0.6 2,255,047 + PfGW456L13_2051 0.77 +0.4 2,255,177 + +0.5 2,255,177 + +0.1 2,255,177 + +0.6 2,255,177 + -0.4 2,255,178 - -1.0 2,255,178 - +1.3 2,255,196 + +0.1 2,255,196 + -0.7 2,255,196 + +0.0 2,255,197 - +2.1
Or see this region's nucleotide sequence