Experiment: Vancomycin 0.125 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_1888 and PfGW456L13_1889 are separated by 220 nucleotides PfGW456L13_1889 and PfGW456L13_1890 overlap by 4 nucleotides
PfGW456L13_1888 - NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12), at 2,079,577 to 2,080,578
_1888
PfGW456L13_1889 - Phosphogluconate dehydratase (EC 4.2.1.12), at 2,080,799 to 2,082,625
_1889
PfGW456L13_1890 - Glucokinase (EC 2.7.1.2), at 2,082,622 to 2,083,581
_1890
Position (kb)
2080
2081
2082
2083 Strain fitness (log2 ratio)
-2
-1
0
1
2
3 at 2079.856 kb on + strand, within PfGW456L13_1888 at 2079.856 kb on + strand, within PfGW456L13_1888 at 2079.856 kb on + strand, within PfGW456L13_1888 at 2079.856 kb on + strand, within PfGW456L13_1888 at 2079.856 kb on + strand, within PfGW456L13_1888 at 2079.857 kb on - strand, within PfGW456L13_1888 at 2079.857 kb on - strand, within PfGW456L13_1888 at 2079.857 kb on - strand at 2079.857 kb on - strand, within PfGW456L13_1888 at 2079.857 kb on - strand, within PfGW456L13_1888 at 2080.001 kb on + strand, within PfGW456L13_1888 at 2080.001 kb on + strand, within PfGW456L13_1888 at 2080.001 kb on + strand, within PfGW456L13_1888 at 2080.002 kb on - strand, within PfGW456L13_1888 at 2080.029 kb on + strand, within PfGW456L13_1888 at 2080.029 kb on + strand, within PfGW456L13_1888 at 2080.029 kb on + strand, within PfGW456L13_1888 at 2080.030 kb on - strand, within PfGW456L13_1888 at 2080.030 kb on - strand, within PfGW456L13_1888 at 2080.030 kb on - strand, within PfGW456L13_1888 at 2080.030 kb on - strand, within PfGW456L13_1888 at 2080.031 kb on + strand, within PfGW456L13_1888 at 2080.031 kb on + strand, within PfGW456L13_1888 at 2080.031 kb on + strand, within PfGW456L13_1888 at 2080.031 kb on + strand, within PfGW456L13_1888 at 2080.032 kb on - strand, within PfGW456L13_1888 at 2080.032 kb on - strand, within PfGW456L13_1888 at 2080.032 kb on - strand, within PfGW456L13_1888 at 2080.032 kb on - strand, within PfGW456L13_1888 at 2080.032 kb on - strand, within PfGW456L13_1888 at 2080.032 kb on - strand, within PfGW456L13_1888 at 2080.176 kb on - strand, within PfGW456L13_1888 at 2080.215 kb on + strand, within PfGW456L13_1888 at 2080.215 kb on + strand, within PfGW456L13_1888 at 2080.216 kb on - strand, within PfGW456L13_1888 at 2080.216 kb on - strand, within PfGW456L13_1888 at 2080.216 kb on - strand at 2080.216 kb on - strand, within PfGW456L13_1888 at 2080.239 kb on + strand, within PfGW456L13_1888 at 2080.239 kb on + strand, within PfGW456L13_1888 at 2080.242 kb on + strand, within PfGW456L13_1888 at 2080.242 kb on + strand, within PfGW456L13_1888 at 2080.242 kb on + strand, within PfGW456L13_1888 at 2080.243 kb on - strand, within PfGW456L13_1888 at 2080.243 kb on - strand, within PfGW456L13_1888 at 2080.243 kb on - strand, within PfGW456L13_1888 at 2080.243 kb on - strand, within PfGW456L13_1888 at 2080.356 kb on + strand, within PfGW456L13_1888 at 2080.356 kb on + strand, within PfGW456L13_1888 at 2080.431 kb on - strand, within PfGW456L13_1888 at 2080.431 kb on - strand, within PfGW456L13_1888 at 2080.503 kb on - strand at 2080.514 kb on + strand at 2080.514 kb on + strand at 2080.514 kb on + strand at 2080.620 kb on + strand at 2080.756 kb on + strand at 2080.756 kb on + strand at 2080.756 kb on + strand at 2080.756 kb on + strand at 2080.756 kb on + strand at 2080.757 kb on - strand at 2080.794 kb on + strand at 2080.795 kb on - strand at 2081.020 kb on + strand, within PfGW456L13_1889 at 2081.020 kb on + strand, within PfGW456L13_1889 at 2081.021 kb on - strand, within PfGW456L13_1889 at 2081.021 kb on - strand, within PfGW456L13_1889 at 2081.021 kb on - strand, within PfGW456L13_1889 at 2081.170 kb on + strand, within PfGW456L13_1889 at 2081.170 kb on + strand, within PfGW456L13_1889 at 2081.387 kb on + strand, within PfGW456L13_1889 at 2081.388 kb on + strand, within PfGW456L13_1889 at 2081.940 kb on - strand, within PfGW456L13_1889 at 2082.411 kb on + strand, within PfGW456L13_1889 at 2082.598 kb on + strand at 2082.599 kb on - strand at 2082.619 kb on + strand at 2082.620 kb on - strand at 2082.620 kb on - strand at 2082.744 kb on + strand, within PfGW456L13_1890 at 2082.744 kb on + strand, within PfGW456L13_1890 at 2082.744 kb on + strand, within PfGW456L13_1890 at 2082.744 kb on + strand, within PfGW456L13_1890 at 2082.744 kb on + strand, within PfGW456L13_1890 at 2082.745 kb on - strand, within PfGW456L13_1890 at 2082.745 kb on - strand, within PfGW456L13_1890 at 2082.745 kb on - strand, within PfGW456L13_1890 at 2082.745 kb on - strand, within PfGW456L13_1890 at 2082.754 kb on + strand, within PfGW456L13_1890 at 2082.754 kb on + strand, within PfGW456L13_1890 at 2082.754 kb on + strand, within PfGW456L13_1890 at 2082.754 kb on + strand, within PfGW456L13_1890 at 2082.849 kb on + strand, within PfGW456L13_1890 at 2082.850 kb on - strand, within PfGW456L13_1890 at 2083.396 kb on + strand, within PfGW456L13_1890 at 2083.396 kb on + strand, within PfGW456L13_1890 at 2083.396 kb on + strand, within PfGW456L13_1890 at 2083.396 kb on + strand, within PfGW456L13_1890 at 2083.397 kb on - strand, within PfGW456L13_1890 at 2083.397 kb on - strand, within PfGW456L13_1890 at 2083.397 kb on - strand, within PfGW456L13_1890 at 2083.397 kb on - strand, within PfGW456L13_1890 at 2083.397 kb on - strand at 2083.397 kb on - strand, within PfGW456L13_1890 at 2083.397 kb on - strand, within PfGW456L13_1890 at 2083.489 kb on + strand at 2083.490 kb on - strand at 2083.528 kb on + strand at 2083.528 kb on + strand at 2083.590 kb on + strand at 2083.597 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.125 mg/ml remove 2,079,856 + PfGW456L13_1888 0.28 -0.1 2,079,856 + PfGW456L13_1888 0.28 -0.6 2,079,856 + PfGW456L13_1888 0.28 -0.8 2,079,856 + PfGW456L13_1888 0.28 -0.4 2,079,856 + PfGW456L13_1888 0.28 +0.3 2,079,857 - PfGW456L13_1888 0.28 -0.2 2,079,857 - PfGW456L13_1888 0.28 -0.3 2,079,857 - -1.6 2,079,857 - PfGW456L13_1888 0.28 -0.6 2,079,857 - PfGW456L13_1888 0.28 +0.6 2,080,001 + PfGW456L13_1888 0.42 -0.0 2,080,001 + PfGW456L13_1888 0.42 +0.9 2,080,001 + PfGW456L13_1888 0.42 -0.1 2,080,002 - PfGW456L13_1888 0.42 +0.8 2,080,029 + PfGW456L13_1888 0.45 +0.8 2,080,029 + PfGW456L13_1888 0.45 -0.3 2,080,029 + PfGW456L13_1888 0.45 -0.7 2,080,030 - PfGW456L13_1888 0.45 -0.9 2,080,030 - PfGW456L13_1888 0.45 +1.1 2,080,030 - PfGW456L13_1888 0.45 -0.8 2,080,030 - PfGW456L13_1888 0.45 -0.5 2,080,031 + PfGW456L13_1888 0.45 -0.3 2,080,031 + PfGW456L13_1888 0.45 -0.2 2,080,031 + PfGW456L13_1888 0.45 -0.7 2,080,031 + PfGW456L13_1888 0.45 +0.0 2,080,032 - PfGW456L13_1888 0.45 -0.7 2,080,032 - PfGW456L13_1888 0.45 +0.6 2,080,032 - PfGW456L13_1888 0.45 +0.6 2,080,032 - PfGW456L13_1888 0.45 +0.9 2,080,032 - PfGW456L13_1888 0.45 +0.6 2,080,032 - PfGW456L13_1888 0.45 -0.1 2,080,176 - PfGW456L13_1888 0.60 +0.4 2,080,215 + PfGW456L13_1888 0.64 -0.0 2,080,215 + PfGW456L13_1888 0.64 +0.8 2,080,216 - PfGW456L13_1888 0.64 +0.6 2,080,216 - PfGW456L13_1888 0.64 -0.2 2,080,216 - +0.3 2,080,216 - PfGW456L13_1888 0.64 +0.7 2,080,239 + PfGW456L13_1888 0.66 -0.2 2,080,239 + PfGW456L13_1888 0.66 -0.4 2,080,242 + PfGW456L13_1888 0.66 -0.2 2,080,242 + PfGW456L13_1888 0.66 -0.7 2,080,242 + PfGW456L13_1888 0.66 +0.0 2,080,243 - PfGW456L13_1888 0.66 +0.6 2,080,243 - PfGW456L13_1888 0.66 +1.2 2,080,243 - PfGW456L13_1888 0.66 +0.0 2,080,243 - PfGW456L13_1888 0.66 -1.0 2,080,356 + PfGW456L13_1888 0.78 +0.3 2,080,356 + PfGW456L13_1888 0.78 -1.3 2,080,431 - PfGW456L13_1888 0.85 +0.8 2,080,431 - PfGW456L13_1888 0.85 -0.1 2,080,503 - +0.4 2,080,514 + +0.3 2,080,514 + -0.1 2,080,514 + +1.7 2,080,620 + -0.8 2,080,756 + -1.9 2,080,756 + -0.9 2,080,756 + +0.1 2,080,756 + +0.7 2,080,756 + -1.7 2,080,757 - -1.3 2,080,794 + +0.4 2,080,795 - -0.8 2,081,020 + PfGW456L13_1889 0.12 -2.3 2,081,020 + PfGW456L13_1889 0.12 -1.3 2,081,021 - PfGW456L13_1889 0.12 +1.4 2,081,021 - PfGW456L13_1889 0.12 -0.9 2,081,021 - PfGW456L13_1889 0.12 -1.6 2,081,170 + PfGW456L13_1889 0.20 -1.6 2,081,170 + PfGW456L13_1889 0.20 -1.3 2,081,387 + PfGW456L13_1889 0.32 +1.1 2,081,388 + PfGW456L13_1889 0.32 -1.9 2,081,940 - PfGW456L13_1889 0.62 -0.9 2,082,411 + PfGW456L13_1889 0.88 -0.1 2,082,598 + -2.6 2,082,599 - -1.0 2,082,619 + -0.1 2,082,620 - +0.5 2,082,620 - -1.2 2,082,744 + PfGW456L13_1890 0.13 -0.0 2,082,744 + PfGW456L13_1890 0.13 +1.4 2,082,744 + PfGW456L13_1890 0.13 +0.0 2,082,744 + PfGW456L13_1890 0.13 +0.0 2,082,744 + PfGW456L13_1890 0.13 -0.1 2,082,745 - PfGW456L13_1890 0.13 -0.1 2,082,745 - PfGW456L13_1890 0.13 -0.4 2,082,745 - PfGW456L13_1890 0.13 +1.4 2,082,745 - PfGW456L13_1890 0.13 -0.5 2,082,754 + PfGW456L13_1890 0.14 -0.9 2,082,754 + PfGW456L13_1890 0.14 +0.2 2,082,754 + PfGW456L13_1890 0.14 +1.0 2,082,754 + PfGW456L13_1890 0.14 -0.8 2,082,849 + PfGW456L13_1890 0.24 -2.1 2,082,850 - PfGW456L13_1890 0.24 -0.3 2,083,396 + PfGW456L13_1890 0.81 +0.4 2,083,396 + PfGW456L13_1890 0.81 +0.0 2,083,396 + PfGW456L13_1890 0.81 -0.5 2,083,396 + PfGW456L13_1890 0.81 -0.4 2,083,397 - PfGW456L13_1890 0.81 -0.2 2,083,397 - PfGW456L13_1890 0.81 +0.1 2,083,397 - PfGW456L13_1890 0.81 +0.6 2,083,397 - PfGW456L13_1890 0.81 -0.2 2,083,397 - +3.0 2,083,397 - PfGW456L13_1890 0.81 +1.2 2,083,397 - PfGW456L13_1890 0.81 -1.3 2,083,489 + -0.1 2,083,490 - +0.4 2,083,528 + -0.6 2,083,528 + +0.3 2,083,590 + +0.0 2,083,597 - +0.9
Or see this region's nucleotide sequence