Experiment: Vancomycin 0.125 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_1158 and PfGW456L13_1159 are separated by 287 nucleotides PfGW456L13_1159 and PfGW456L13_1160 overlap by 8 nucleotides PfGW456L13_1160 and PfGW456L13_1161 are separated by 83 nucleotides PfGW456L13_1161 and PfGW456L13_1162 are separated by 77 nucleotides
PfGW456L13_1158 - Acetylornithine aminotransferase (EC 2.6.1.11), at 1,289,282 to 1,290,565
_1158
PfGW456L13_1159 - Putative cytoplasmic protein, at 1,290,853 to 1,291,173
_1159
PfGW456L13_1160 - Putative DNA-binding protein in cluster with Type I restriction-modification system, at 1,291,166 to 1,291,486
_1160
PfGW456L13_1161 - Stress induced hydrophobic peptide, at 1,291,570 to 1,291,728
_1161
PfGW456L13_1162 - Mobile element protein, at 1,291,806 to 1,292,642
_1162
Position (kb)
1291
1292 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 1290.459 kb on + strand at 1290.460 kb on - strand at 1290.460 kb on - strand at 1290.580 kb on + strand at 1290.580 kb on + strand at 1290.580 kb on + strand at 1290.580 kb on + strand at 1290.580 kb on + strand at 1290.580 kb on + strand at 1290.581 kb on - strand at 1290.581 kb on - strand at 1290.581 kb on - strand at 1290.608 kb on + strand at 1290.608 kb on + strand at 1290.608 kb on + strand at 1290.608 kb on + strand at 1290.608 kb on + strand at 1290.609 kb on - strand at 1290.701 kb on + strand at 1290.701 kb on + strand at 1290.712 kb on + strand at 1290.713 kb on - strand at 1290.988 kb on - strand, within PfGW456L13_1159 at 1291.018 kb on + strand, within PfGW456L13_1159 at 1291.019 kb on - strand, within PfGW456L13_1159 at 1291.053 kb on + strand, within PfGW456L13_1159 at 1291.053 kb on + strand, within PfGW456L13_1159 at 1291.054 kb on - strand, within PfGW456L13_1159 at 1291.054 kb on - strand, within PfGW456L13_1159 at 1291.054 kb on - strand, within PfGW456L13_1159 at 1291.054 kb on - strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.099 kb on + strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.100 kb on - strand, within PfGW456L13_1159 at 1291.160 kb on + strand at 1291.160 kb on + strand at 1291.161 kb on - strand at 1291.161 kb on - strand at 1291.163 kb on + strand at 1291.163 kb on + strand at 1291.163 kb on + strand at 1291.163 kb on + strand at 1291.163 kb on + strand at 1291.163 kb on + strand at 1291.163 kb on + strand at 1291.163 kb on + strand at 1291.163 kb on + strand at 1291.163 kb on + strand at 1291.163 kb on + strand at 1291.163 kb on + strand at 1291.163 kb on + strand at 1291.164 kb on - strand at 1291.164 kb on - strand at 1291.164 kb on - strand at 1291.164 kb on - strand at 1291.164 kb on - strand at 1291.164 kb on - strand at 1291.164 kb on - strand at 1291.164 kb on - strand at 1291.226 kb on + strand, within PfGW456L13_1160 at 1291.226 kb on + strand, within PfGW456L13_1160 at 1291.226 kb on + strand, within PfGW456L13_1160 at 1291.226 kb on + strand, within PfGW456L13_1160 at 1291.226 kb on + strand, within PfGW456L13_1160 at 1291.226 kb on + strand, within PfGW456L13_1160 at 1291.226 kb on + strand, within PfGW456L13_1160 at 1291.227 kb on - strand, within PfGW456L13_1160 at 1291.227 kb on - strand, within PfGW456L13_1160 at 1291.227 kb on - strand, within PfGW456L13_1160 at 1291.227 kb on - strand, within PfGW456L13_1160 at 1291.227 kb on - strand, within PfGW456L13_1160 at 1291.233 kb on + strand, within PfGW456L13_1160 at 1291.233 kb on + strand, within PfGW456L13_1160 at 1291.367 kb on + strand, within PfGW456L13_1160 at 1291.476 kb on + strand at 1291.477 kb on - strand at 1291.525 kb on + strand at 1291.525 kb on + strand at 1291.525 kb on + strand at 1291.525 kb on + strand at 1291.526 kb on - strand at 1291.532 kb on - strand at 1291.631 kb on + strand, within PfGW456L13_1161 at 1291.631 kb on + strand, within PfGW456L13_1161 at 1291.631 kb on + strand, within PfGW456L13_1161 at 1291.631 kb on + strand, within PfGW456L13_1161 at 1291.632 kb on - strand, within PfGW456L13_1161 at 1291.659 kb on + strand, within PfGW456L13_1161 at 1291.660 kb on - strand, within PfGW456L13_1161 at 1291.660 kb on - strand, within PfGW456L13_1161 at 1291.681 kb on + strand, within PfGW456L13_1161 at 1291.682 kb on - strand, within PfGW456L13_1161 at 1291.708 kb on + strand, within PfGW456L13_1161 at 1291.708 kb on + strand, within PfGW456L13_1161 at 1291.708 kb on + strand, within PfGW456L13_1161 at 1291.708 kb on + strand, within PfGW456L13_1161 at 1291.708 kb on + strand, within PfGW456L13_1161 at 1291.708 kb on + strand, within PfGW456L13_1161 at 1291.709 kb on - strand, within PfGW456L13_1161 at 1291.709 kb on - strand, within PfGW456L13_1161 at 1291.709 kb on - strand, within PfGW456L13_1161 at 1291.709 kb on - strand, within PfGW456L13_1161 at 1291.709 kb on - strand, within PfGW456L13_1161 at 1291.709 kb on - strand, within PfGW456L13_1161 at 1291.743 kb on - strand at 1291.782 kb on - strand at 1291.782 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.125 mg/ml remove 1,290,459 + -0.6 1,290,460 - +0.9 1,290,460 - -0.7 1,290,580 + -1.2 1,290,580 + +0.7 1,290,580 + +0.2 1,290,580 + +0.9 1,290,580 + +0.2 1,290,580 + +0.9 1,290,581 - -0.0 1,290,581 - +0.5 1,290,581 - -0.0 1,290,608 + -0.1 1,290,608 + +0.7 1,290,608 + +0.8 1,290,608 + -1.0 1,290,608 + +0.3 1,290,609 - +0.2 1,290,701 + -0.6 1,290,701 + -1.2 1,290,712 + +0.1 1,290,713 - -0.1 1,290,988 - PfGW456L13_1159 0.42 -3.0 1,291,018 + PfGW456L13_1159 0.51 +1.1 1,291,019 - PfGW456L13_1159 0.52 +0.5 1,291,053 + PfGW456L13_1159 0.62 +0.4 1,291,053 + PfGW456L13_1159 0.62 +1.0 1,291,054 - PfGW456L13_1159 0.63 +0.1 1,291,054 - PfGW456L13_1159 0.63 +0.4 1,291,054 - PfGW456L13_1159 0.63 +1.1 1,291,054 - PfGW456L13_1159 0.63 +0.8 1,291,099 + PfGW456L13_1159 0.77 +1.0 1,291,099 + PfGW456L13_1159 0.77 +1.0 1,291,099 + PfGW456L13_1159 0.77 -0.7 1,291,099 + PfGW456L13_1159 0.77 -0.3 1,291,099 + PfGW456L13_1159 0.77 -0.5 1,291,099 + PfGW456L13_1159 0.77 -1.0 1,291,099 + PfGW456L13_1159 0.77 -0.2 1,291,099 + PfGW456L13_1159 0.77 +0.5 1,291,099 + PfGW456L13_1159 0.77 +0.4 1,291,099 + PfGW456L13_1159 0.77 -2.1 1,291,099 + PfGW456L13_1159 0.77 -0.4 1,291,099 + PfGW456L13_1159 0.77 +0.6 1,291,099 + PfGW456L13_1159 0.77 -0.2 1,291,099 + PfGW456L13_1159 0.77 +0.3 1,291,099 + PfGW456L13_1159 0.77 -0.7 1,291,099 + PfGW456L13_1159 0.77 -1.9 1,291,099 + PfGW456L13_1159 0.77 -0.2 1,291,099 + PfGW456L13_1159 0.77 -0.1 1,291,099 + PfGW456L13_1159 0.77 +0.1 1,291,099 + PfGW456L13_1159 0.77 -0.4 1,291,099 + PfGW456L13_1159 0.77 -2.6 1,291,099 + PfGW456L13_1159 0.77 +1.1 1,291,099 + PfGW456L13_1159 0.77 -0.6 1,291,099 + PfGW456L13_1159 0.77 -0.6 1,291,100 - PfGW456L13_1159 0.77 +0.2 1,291,100 - PfGW456L13_1159 0.77 +0.3 1,291,100 - PfGW456L13_1159 0.77 -1.3 1,291,100 - PfGW456L13_1159 0.77 +1.7 1,291,100 - PfGW456L13_1159 0.77 -0.1 1,291,100 - +0.8 1,291,100 - PfGW456L13_1159 0.77 +0.3 1,291,100 - +0.3 1,291,100 - PfGW456L13_1159 0.77 +0.2 1,291,100 - PfGW456L13_1159 0.77 -1.4 1,291,100 - PfGW456L13_1159 0.77 -0.7 1,291,100 - PfGW456L13_1159 0.77 -0.0 1,291,100 - PfGW456L13_1159 0.77 +0.0 1,291,100 - PfGW456L13_1159 0.77 -0.7 1,291,100 - PfGW456L13_1159 0.77 -1.4 1,291,100 - PfGW456L13_1159 0.77 +0.4 1,291,100 - PfGW456L13_1159 0.77 -1.1 1,291,100 - PfGW456L13_1159 0.77 +1.1 1,291,100 - PfGW456L13_1159 0.77 -0.3 1,291,100 - PfGW456L13_1159 0.77 +0.3 1,291,100 - PfGW456L13_1159 0.77 +0.0 1,291,100 - PfGW456L13_1159 0.77 -0.3 1,291,100 - PfGW456L13_1159 0.77 +0.4 1,291,100 - PfGW456L13_1159 0.77 -0.1 1,291,160 + -1.4 1,291,160 + +1.0 1,291,161 - -0.2 1,291,161 - +0.7 1,291,163 + -0.3 1,291,163 + +0.2 1,291,163 + +0.3 1,291,163 + -1.0 1,291,163 + +0.1 1,291,163 + +1.2 1,291,163 + +0.6 1,291,163 + -0.6 1,291,163 + +2.1 1,291,163 + -0.0 1,291,163 + -0.5 1,291,163 + -0.8 1,291,163 + -0.5 1,291,164 - +0.9 1,291,164 - +0.7 1,291,164 - -1.5 1,291,164 - -0.2 1,291,164 - -1.2 1,291,164 - -0.5 1,291,164 - +0.3 1,291,164 - +0.8 1,291,226 + PfGW456L13_1160 0.19 -2.6 1,291,226 + PfGW456L13_1160 0.19 -1.0 1,291,226 + PfGW456L13_1160 0.19 +0.0 1,291,226 + PfGW456L13_1160 0.19 -0.7 1,291,226 + PfGW456L13_1160 0.19 -0.2 1,291,226 + PfGW456L13_1160 0.19 -0.9 1,291,226 + PfGW456L13_1160 0.19 -2.9 1,291,227 - PfGW456L13_1160 0.19 -0.2 1,291,227 - PfGW456L13_1160 0.19 -1.2 1,291,227 - PfGW456L13_1160 0.19 -0.4 1,291,227 - PfGW456L13_1160 0.19 -0.5 1,291,227 - PfGW456L13_1160 0.19 -0.7 1,291,233 + PfGW456L13_1160 0.21 -0.8 1,291,233 + PfGW456L13_1160 0.21 -0.0 1,291,367 + PfGW456L13_1160 0.63 -0.6 1,291,476 + -0.3 1,291,477 - +0.1 1,291,525 + -2.0 1,291,525 + +0.6 1,291,525 + +1.0 1,291,525 + +1.1 1,291,526 - +0.9 1,291,532 - +0.5 1,291,631 + PfGW456L13_1161 0.38 -0.3 1,291,631 + PfGW456L13_1161 0.38 -0.6 1,291,631 + PfGW456L13_1161 0.38 +0.0 1,291,631 + PfGW456L13_1161 0.38 -0.6 1,291,632 - PfGW456L13_1161 0.39 +0.6 1,291,659 + PfGW456L13_1161 0.56 +0.7 1,291,660 - PfGW456L13_1161 0.57 -1.0 1,291,660 - PfGW456L13_1161 0.57 +0.2 1,291,681 + PfGW456L13_1161 0.70 -0.5 1,291,682 - PfGW456L13_1161 0.70 -0.2 1,291,708 + PfGW456L13_1161 0.87 -0.6 1,291,708 + PfGW456L13_1161 0.87 +0.3 1,291,708 + PfGW456L13_1161 0.87 +0.8 1,291,708 + PfGW456L13_1161 0.87 -1.7 1,291,708 + PfGW456L13_1161 0.87 +0.5 1,291,708 + PfGW456L13_1161 0.87 +0.5 1,291,709 - PfGW456L13_1161 0.87 +0.3 1,291,709 - PfGW456L13_1161 0.87 +0.6 1,291,709 - PfGW456L13_1161 0.87 -0.2 1,291,709 - PfGW456L13_1161 0.87 -0.0 1,291,709 - PfGW456L13_1161 0.87 +0.6 1,291,709 - PfGW456L13_1161 0.87 +1.7 1,291,743 - -1.2 1,291,782 - -0.3 1,291,782 - +0.6
Or see this region's nucleotide sequence