Experiment: Vancomycin 0.125 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_1007 and PfGW456L13_1008 are separated by 181 nucleotides PfGW456L13_1008 and PfGW456L13_1009 are separated by 4 nucleotides PfGW456L13_1009 and PfGW456L13_1010 are separated by 10 nucleotides PfGW456L13_1010 and PfGW456L13_1011 are separated by 35 nucleotides
PfGW456L13_1007 - Homoserine O-acetyltransferase (EC 2.3.1.31), at 1,119,650 to 1,120,789
_1007
PfGW456L13_1008 - COG1872, at 1,120,971 to 1,121,267
_1008
PfGW456L13_1009 - Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock), at 1,121,272 to 1,121,862
_1009
PfGW456L13_1010 - Pyrroline-5-carboxylate reductase (EC 1.5.1.2), at 1,121,873 to 1,122,691
_1010
PfGW456L13_1011 - Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC, at 1,122,727 to 1,123,413
_1011
Position (kb)
1121
1122 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2
3 at 1120.281 kb on + strand, within PfGW456L13_1007 at 1120.281 kb on + strand, within PfGW456L13_1007 at 1120.281 kb on + strand, within PfGW456L13_1007 at 1120.281 kb on + strand, within PfGW456L13_1007 at 1120.282 kb on - strand, within PfGW456L13_1007 at 1120.282 kb on - strand, within PfGW456L13_1007 at 1120.282 kb on - strand, within PfGW456L13_1007 at 1120.406 kb on + strand, within PfGW456L13_1007 at 1120.665 kb on + strand, within PfGW456L13_1007 at 1120.665 kb on + strand, within PfGW456L13_1007 at 1120.666 kb on - strand, within PfGW456L13_1007 at 1120.666 kb on - strand, within PfGW456L13_1007 at 1120.666 kb on - strand, within PfGW456L13_1007 at 1120.674 kb on + strand, within PfGW456L13_1007 at 1120.674 kb on + strand, within PfGW456L13_1007 at 1120.674 kb on + strand, within PfGW456L13_1007 at 1120.674 kb on + strand, within PfGW456L13_1007 at 1120.675 kb on - strand, within PfGW456L13_1007 at 1120.675 kb on - strand, within PfGW456L13_1007 at 1120.675 kb on - strand, within PfGW456L13_1007 at 1120.686 kb on + strand at 1120.687 kb on - strand at 1120.752 kb on - strand at 1120.817 kb on + strand at 1120.817 kb on + strand at 1120.817 kb on + strand at 1120.817 kb on + strand at 1120.817 kb on + strand at 1120.818 kb on - strand at 1120.818 kb on - strand at 1120.818 kb on - strand at 1120.818 kb on - strand at 1120.818 kb on - strand at 1120.823 kb on + strand at 1120.824 kb on - strand at 1120.824 kb on - strand at 1121.119 kb on + strand, within PfGW456L13_1008 at 1121.119 kb on + strand, within PfGW456L13_1008 at 1121.119 kb on + strand, within PfGW456L13_1008 at 1121.119 kb on + strand, within PfGW456L13_1008 at 1121.120 kb on - strand, within PfGW456L13_1008 at 1121.120 kb on - strand, within PfGW456L13_1008 at 1121.120 kb on - strand, within PfGW456L13_1008 at 1121.467 kb on - strand, within PfGW456L13_1009 at 1121.678 kb on - strand, within PfGW456L13_1009 at 1121.753 kb on + strand, within PfGW456L13_1009 at 1121.753 kb on + strand, within PfGW456L13_1009 at 1121.754 kb on - strand, within PfGW456L13_1009 at 1121.779 kb on + strand, within PfGW456L13_1009 at 1121.834 kb on + strand at 1121.834 kb on + strand at 1121.834 kb on + strand at 1121.847 kb on + strand at 1122.018 kb on - strand, within PfGW456L13_1010 at 1122.052 kb on + strand, within PfGW456L13_1010 at 1122.052 kb on + strand, within PfGW456L13_1010 at 1122.053 kb on - strand, within PfGW456L13_1010 at 1122.053 kb on - strand, within PfGW456L13_1010 at 1122.053 kb on - strand, within PfGW456L13_1010 at 1122.053 kb on - strand, within PfGW456L13_1010 at 1122.053 kb on - strand, within PfGW456L13_1010 at 1122.159 kb on + strand, within PfGW456L13_1010 at 1122.160 kb on - strand, within PfGW456L13_1010 at 1122.221 kb on + strand, within PfGW456L13_1010 at 1122.222 kb on - strand, within PfGW456L13_1010 at 1122.318 kb on - strand, within PfGW456L13_1010 at 1122.318 kb on - strand, within PfGW456L13_1010 at 1122.539 kb on + strand, within PfGW456L13_1010 at 1122.540 kb on - strand, within PfGW456L13_1010 at 1122.540 kb on - strand, within PfGW456L13_1010 at 1122.540 kb on - strand, within PfGW456L13_1010 at 1122.676 kb on + strand at 1122.676 kb on + strand at 1122.676 kb on + strand at 1122.676 kb on + strand at 1122.676 kb on + strand at 1122.676 kb on + strand at 1122.677 kb on - strand at 1122.677 kb on - strand at 1122.677 kb on - strand at 1122.677 kb on - strand at 1122.677 kb on - strand at 1122.677 kb on - strand at 1122.677 kb on - strand at 1122.702 kb on + strand at 1122.702 kb on + strand at 1122.702 kb on + strand at 1122.702 kb on + strand at 1122.702 kb on + strand at 1122.702 kb on + strand at 1122.703 kb on - strand at 1122.703 kb on - strand at 1122.703 kb on - strand at 1122.703 kb on - strand at 1122.703 kb on - strand at 1122.703 kb on - strand at 1122.703 kb on - strand at 1122.703 kb on - strand at 1122.703 kb on - strand at 1122.704 kb on + strand at 1122.704 kb on + strand at 1122.705 kb on - strand at 1122.740 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.125 mg/ml remove 1,120,281 + PfGW456L13_1007 0.55 -0.1 1,120,281 + PfGW456L13_1007 0.55 -0.1 1,120,281 + PfGW456L13_1007 0.55 +0.4 1,120,281 + PfGW456L13_1007 0.55 +0.1 1,120,282 - PfGW456L13_1007 0.55 +0.2 1,120,282 - PfGW456L13_1007 0.55 +0.6 1,120,282 - PfGW456L13_1007 0.55 +0.6 1,120,406 + PfGW456L13_1007 0.66 +0.3 1,120,665 + PfGW456L13_1007 0.89 -0.2 1,120,665 + PfGW456L13_1007 0.89 -1.5 1,120,666 - PfGW456L13_1007 0.89 -0.9 1,120,666 - PfGW456L13_1007 0.89 -0.1 1,120,666 - PfGW456L13_1007 0.89 +0.6 1,120,674 + PfGW456L13_1007 0.90 -0.3 1,120,674 + PfGW456L13_1007 0.90 +1.1 1,120,674 + PfGW456L13_1007 0.90 +0.5 1,120,674 + PfGW456L13_1007 0.90 -0.5 1,120,675 - PfGW456L13_1007 0.90 +0.5 1,120,675 - PfGW456L13_1007 0.90 +0.6 1,120,675 - PfGW456L13_1007 0.90 -0.2 1,120,686 + -0.1 1,120,687 - +0.7 1,120,752 - -0.4 1,120,817 + +0.5 1,120,817 + +0.4 1,120,817 + -1.4 1,120,817 + -0.4 1,120,817 + +0.2 1,120,818 - -0.2 1,120,818 - +0.5 1,120,818 - +1.4 1,120,818 - -1.2 1,120,818 - +0.3 1,120,823 + +0.7 1,120,824 - -0.3 1,120,824 - -0.3 1,121,119 + PfGW456L13_1008 0.50 +0.6 1,121,119 + PfGW456L13_1008 0.50 +0.9 1,121,119 + PfGW456L13_1008 0.50 +0.3 1,121,119 + PfGW456L13_1008 0.50 +0.3 1,121,120 - PfGW456L13_1008 0.50 -0.4 1,121,120 - PfGW456L13_1008 0.50 +0.2 1,121,120 - PfGW456L13_1008 0.50 +0.0 1,121,467 - PfGW456L13_1009 0.33 -0.2 1,121,678 - PfGW456L13_1009 0.69 +0.2 1,121,753 + PfGW456L13_1009 0.81 -3.3 1,121,753 + PfGW456L13_1009 0.81 -1.9 1,121,754 - PfGW456L13_1009 0.82 -2.1 1,121,779 + PfGW456L13_1009 0.86 +0.9 1,121,834 + -0.7 1,121,834 + -1.7 1,121,834 + +0.3 1,121,847 + -0.4 1,122,018 - PfGW456L13_1010 0.18 +0.1 1,122,052 + PfGW456L13_1010 0.22 -1.0 1,122,052 + PfGW456L13_1010 0.22 -0.2 1,122,053 - PfGW456L13_1010 0.22 +0.2 1,122,053 - PfGW456L13_1010 0.22 -1.1 1,122,053 - PfGW456L13_1010 0.22 -0.2 1,122,053 - PfGW456L13_1010 0.22 -1.1 1,122,053 - PfGW456L13_1010 0.22 -0.4 1,122,159 + PfGW456L13_1010 0.35 +0.1 1,122,160 - PfGW456L13_1010 0.35 +0.3 1,122,221 + PfGW456L13_1010 0.42 +0.2 1,122,222 - PfGW456L13_1010 0.43 +0.0 1,122,318 - PfGW456L13_1010 0.54 -1.2 1,122,318 - PfGW456L13_1010 0.54 +0.7 1,122,539 + PfGW456L13_1010 0.81 -1.1 1,122,540 - PfGW456L13_1010 0.81 +1.0 1,122,540 - PfGW456L13_1010 0.81 -0.5 1,122,540 - PfGW456L13_1010 0.81 +0.8 1,122,676 + +1.1 1,122,676 + +3.2 1,122,676 + +0.9 1,122,676 + +0.5 1,122,676 + +0.4 1,122,676 + -1.1 1,122,677 - -3.4 1,122,677 - -0.5 1,122,677 - -0.2 1,122,677 - -0.2 1,122,677 - -0.8 1,122,677 - -0.9 1,122,677 - -0.6 1,122,702 + -0.4 1,122,702 + -0.5 1,122,702 + -0.8 1,122,702 + +0.1 1,122,702 + -0.9 1,122,702 + -1.1 1,122,703 - -1.4 1,122,703 - +0.4 1,122,703 - -1.0 1,122,703 - +0.2 1,122,703 - +0.1 1,122,703 - -0.9 1,122,703 - +0.1 1,122,703 - -0.3 1,122,703 - +2.1 1,122,704 + +0.5 1,122,704 + +0.9 1,122,705 - +1.7 1,122,740 + +0.0
Or see this region's nucleotide sequence