Strain Fitness in Escherichia coli ECOR27 around NOLOHH_15835

Experiment: Sodium-DL-Lactate

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 nthisD and hisG are separated by 5 nucleotideshisG and hisL are separated by 145 nucleotideshisL and yefM are separated by 282 nucleotidesyefM and yoeB overlap by 4 nucleotides NOLOHH_15830: hisD - Histidinol dehydrogenase, at 3,120,789 to 3,122,093 hisD NOLOHH_15835: hisG - ATP phosphoribosyltransferase, at 3,122,099 to 3,122,998 hisG NOLOHH_15840: hisL - his operon leader peptide, at 3,123,144 to 3,123,194 hisL NOLOHH_15845: yefM - YoeB-YefM toxin-antitoxin system antitoxin YefM, at 3,123,477 to 3,123,728 yefM NOLOHH_15850: yoeB - type II toxin-antitoxin system mRNA interferase toxin YoeB, at 3,123,725 to 3,123,979 yoeB Position (kb) 3122 3123Strain fitness (log2 ratio) -6 -5 -4 -3 -2 -1 0 1at 3121.353 kb on - strand, within hisDat 3121.548 kb on - strand, within hisDat 3121.666 kb on - strand, within hisDat 3121.669 kb on - strand, within hisDat 3121.669 kb on - strand, within hisDat 3121.669 kb on - strand, within hisDat 3121.704 kb on - strand, within hisDat 3121.705 kb on + strand, within hisDat 3121.705 kb on + strand, within hisDat 3121.706 kb on - strand, within hisDat 3121.706 kb on - strand, within hisDat 3121.706 kb on - strand, within hisDat 3121.706 kb on - strand, within hisDat 3121.767 kb on + strand, within hisDat 3121.768 kb on - strand, within hisDat 3121.768 kb on - strand, within hisDat 3121.768 kb on - strand, within hisDat 3121.843 kb on - strand, within hisDat 3122.211 kb on - strand, within hisGat 3122.211 kb on - strand, within hisGat 3122.316 kb on + strand, within hisGat 3122.317 kb on - strand, within hisGat 3122.317 kb on - strand, within hisGat 3122.350 kb on + strand, within hisGat 3122.633 kb on + strand, within hisGat 3122.949 kb on - strandat 3123.005 kb on - strandat 3123.015 kb on - strandat 3123.233 kb on - strandat 3123.238 kb on - strandat 3123.272 kb on + strandat 3123.276 kb on + strandat 3123.328 kb on - strandat 3123.363 kb on + strandat 3123.396 kb on - strandat 3123.405 kb on + strandat 3123.416 kb on + strandat 3123.419 kb on + strandat 3123.419 kb on + strandat 3123.419 kb on + strandat 3123.423 kb on + strandat 3123.732 kb on + strandat 3123.732 kb on + strandat 3123.761 kb on + strand, within yoeBat 3123.784 kb on + strand, within yoeBat 3123.784 kb on + strand, within yoeBat 3123.924 kb on + strand, within yoeBat 3123.926 kb on + strand, within yoeBat 3123.993 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Sodium-DL-Lactate
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3,121,353 - hisD NOLOHH_15830 0.43 -4.4
3,121,548 - hisD NOLOHH_15830 0.58 -6.2
3,121,666 - hisD NOLOHH_15830 0.67 -2.9
3,121,669 - hisD NOLOHH_15830 0.67 -3.0
3,121,669 - hisD NOLOHH_15830 0.67 -3.4
3,121,669 - hisD NOLOHH_15830 0.67 -3.7
3,121,704 - hisD NOLOHH_15830 0.70 -3.6
3,121,705 + hisD NOLOHH_15830 0.70 -2.1
3,121,705 + hisD NOLOHH_15830 0.70 -2.6
3,121,706 - hisD NOLOHH_15830 0.70 -4.0
3,121,706 - hisD NOLOHH_15830 0.70 -4.4
3,121,706 - hisD NOLOHH_15830 0.70 -2.5
3,121,706 - hisD NOLOHH_15830 0.70 -4.2
3,121,767 + hisD NOLOHH_15830 0.75 -1.9
3,121,768 - hisD NOLOHH_15830 0.75 -5.4
3,121,768 - hisD NOLOHH_15830 0.75 -3.3
3,121,768 - hisD NOLOHH_15830 0.75 -4.8
3,121,843 - hisD NOLOHH_15830 0.81 -5.2
3,122,211 - hisG NOLOHH_15835 0.12 -2.6
3,122,211 - hisG NOLOHH_15835 0.12 -2.7
3,122,316 + hisG NOLOHH_15835 0.24 -0.9
3,122,317 - hisG NOLOHH_15835 0.24 -1.2
3,122,317 - hisG NOLOHH_15835 0.24 -0.2
3,122,350 + hisG NOLOHH_15835 0.28 -3.6
3,122,633 + hisG NOLOHH_15835 0.59 -1.1
3,122,949 - -5.2
3,123,005 - -1.7
3,123,015 - +0.3
3,123,233 - -0.3
3,123,238 - -1.0
3,123,272 + -0.1
3,123,276 + -0.1
3,123,328 - +0.9
3,123,363 + +0.2
3,123,396 - -1.8
3,123,405 + -0.5
3,123,416 + -0.3
3,123,419 + +1.4
3,123,419 + -0.9
3,123,419 + +0.8
3,123,423 + +1.5
3,123,732 + +0.0
3,123,732 + -0.0
3,123,761 + yoeB NOLOHH_15850 0.14 -0.1
3,123,784 + yoeB NOLOHH_15850 0.23 -0.3
3,123,784 + yoeB NOLOHH_15850 0.23 +0.1
3,123,924 + yoeB NOLOHH_15850 0.78 -0.2
3,123,926 + yoeB NOLOHH_15850 0.79 +0.2
3,123,993 + +0.7

Or see this region's nucleotide sequence