Strain Fitness in Escherichia coli ECOR27 around NOLOHH_15825

Experiment: Sodium-DL-Lactate

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 nthisB and hisC overlap by 1 nucleotideshisC and hisD overlap by 4 nucleotides NOLOHH_15820: hisB - bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB, at 3,118,655 to 3,119,722 hisB NOLOHH_15825: hisC - histidinol-phosphate transaminase, at 3,119,722 to 3,120,792 hisC NOLOHH_15830: hisD - Histidinol dehydrogenase, at 3,120,789 to 3,122,093 hisD Position (kb) 3119 3120 3121Strain fitness (log2 ratio) -6 -5 -4 -3 -2 -1 0 1at 3118.766 kb on - strand, within hisBat 3118.880 kb on - strand, within hisBat 3118.880 kb on - strand, within hisBat 3118.880 kb on - strand, within hisBat 3118.907 kb on - strand, within hisBat 3119.050 kb on - strand, within hisBat 3119.141 kb on - strand, within hisBat 3119.346 kb on + strand, within hisBat 3119.346 kb on + strand, within hisBat 3119.347 kb on - strand, within hisBat 3119.741 kb on - strandat 3119.818 kb on - strandat 3119.831 kb on - strand, within hisCat 3119.860 kb on - strand, within hisCat 3119.898 kb on - strand, within hisCat 3119.961 kb on - strand, within hisCat 3120.166 kb on + strand, within hisCat 3120.233 kb on + strand, within hisCat 3120.234 kb on - strand, within hisCat 3120.234 kb on - strand, within hisCat 3120.341 kb on + strand, within hisCat 3120.341 kb on + strand, within hisCat 3120.342 kb on - strand, within hisCat 3120.382 kb on + strand, within hisCat 3120.575 kb on - strand, within hisCat 3120.734 kb on + strandat 3120.735 kb on - strandat 3120.777 kb on + strandat 3120.778 kb on - strandat 3120.804 kb on - strandat 3120.926 kb on + strand, within hisDat 3120.926 kb on + strand, within hisDat 3120.980 kb on - strand, within hisDat 3120.980 kb on - strand, within hisDat 3120.990 kb on + strand, within hisDat 3121.353 kb on - strand, within hisDat 3121.548 kb on - strand, within hisDat 3121.666 kb on - strand, within hisDat 3121.669 kb on - strand, within hisDat 3121.669 kb on - strand, within hisDat 3121.669 kb on - strand, within hisDat 3121.704 kb on - strand, within hisDat 3121.705 kb on + strand, within hisDat 3121.705 kb on + strand, within hisDat 3121.706 kb on - strand, within hisDat 3121.706 kb on - strand, within hisDat 3121.706 kb on - strand, within hisDat 3121.706 kb on - strand, within hisDat 3121.767 kb on + strand, within hisDat 3121.768 kb on - strand, within hisDat 3121.768 kb on - strand, within hisDat 3121.768 kb on - strand, within hisD

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Per-strain Table

Position Strand Gene LocusTag Fraction Sodium-DL-Lactate
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3,118,766 - hisB NOLOHH_15820 0.10 -2.9
3,118,880 - hisB NOLOHH_15820 0.21 -2.4
3,118,880 - hisB NOLOHH_15820 0.21 -3.9
3,118,880 - hisB NOLOHH_15820 0.21 -2.6
3,118,907 - hisB NOLOHH_15820 0.24 -5.4
3,119,050 - hisB NOLOHH_15820 0.37 -3.9
3,119,141 - hisB NOLOHH_15820 0.46 -5.2
3,119,346 + hisB NOLOHH_15820 0.65 -1.5
3,119,346 + hisB NOLOHH_15820 0.65 -1.8
3,119,347 - hisB NOLOHH_15820 0.65 -3.5
3,119,741 - -0.0
3,119,818 - -4.3
3,119,831 - hisC NOLOHH_15825 0.10 -1.7
3,119,860 - hisC NOLOHH_15825 0.13 -4.3
3,119,898 - hisC NOLOHH_15825 0.16 -3.0
3,119,961 - hisC NOLOHH_15825 0.22 -3.9
3,120,166 + hisC NOLOHH_15825 0.41 -2.9
3,120,233 + hisC NOLOHH_15825 0.48 -4.9
3,120,234 - hisC NOLOHH_15825 0.48 -3.7
3,120,234 - hisC NOLOHH_15825 0.48 -2.6
3,120,341 + hisC NOLOHH_15825 0.58 -1.7
3,120,341 + hisC NOLOHH_15825 0.58 -4.3
3,120,342 - hisC NOLOHH_15825 0.58 -4.1
3,120,382 + hisC NOLOHH_15825 0.62 -3.5
3,120,575 - hisC NOLOHH_15825 0.80 -5.7
3,120,734 + -4.2
3,120,735 - -2.3
3,120,777 + -3.5
3,120,778 - -1.7
3,120,804 - -0.8
3,120,926 + hisD NOLOHH_15830 0.10 -1.8
3,120,926 + hisD NOLOHH_15830 0.10 -4.0
3,120,980 - hisD NOLOHH_15830 0.15 -4.1
3,120,980 - hisD NOLOHH_15830 0.15 -3.5
3,120,990 + hisD NOLOHH_15830 0.15 -4.7
3,121,353 - hisD NOLOHH_15830 0.43 -4.4
3,121,548 - hisD NOLOHH_15830 0.58 -6.2
3,121,666 - hisD NOLOHH_15830 0.67 -2.9
3,121,669 - hisD NOLOHH_15830 0.67 -3.0
3,121,669 - hisD NOLOHH_15830 0.67 -3.4
3,121,669 - hisD NOLOHH_15830 0.67 -3.7
3,121,704 - hisD NOLOHH_15830 0.70 -3.6
3,121,705 + hisD NOLOHH_15830 0.70 -2.1
3,121,705 + hisD NOLOHH_15830 0.70 -2.6
3,121,706 - hisD NOLOHH_15830 0.70 -4.0
3,121,706 - hisD NOLOHH_15830 0.70 -4.4
3,121,706 - hisD NOLOHH_15830 0.70 -2.5
3,121,706 - hisD NOLOHH_15830 0.70 -4.2
3,121,767 + hisD NOLOHH_15830 0.75 -1.9
3,121,768 - hisD NOLOHH_15830 0.75 -5.4
3,121,768 - hisD NOLOHH_15830 0.75 -3.3
3,121,768 - hisD NOLOHH_15830 0.75 -4.8

Or see this region's nucleotide sequence