Strain Fitness in Escherichia coli ECOR38 around HEPCGN_18105

Experiment: Sodium-DL-Lactate

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntkpsM and kpsT overlap by 4 nucleotideskpsT and neuD are separated by 49 nucleotidesneuD and neuB overlap by 4 nucleotides HEPCGN_18100: kpsM - Polysialic acid transport protein, at 2,369,451 to 2,370,227 kpsM HEPCGN_18105: kpsT - Polysialic acid transport ATP-binding protein, at 2,370,224 to 2,370,883 kpsT HEPCGN_18110: neuD - NeuD protein involved in sialic acid synthesis, at 2,370,933 to 2,371,556 neuD HEPCGN_18115: neuB - N-acylneuraminate-9-phosphate synthase, at 2,371,553 to 2,372,593 neuB Position (kb) 2370 2371Strain fitness (log2 ratio) -2 -1 0 1at 2369.390 kb on - strandat 2369.421 kb on + strandat 2369.621 kb on + strand, within kpsMat 2369.684 kb on + strand, within kpsMat 2369.685 kb on - strand, within kpsMat 2369.702 kb on + strand, within kpsMat 2369.711 kb on + strand, within kpsMat 2369.762 kb on + strand, within kpsMat 2369.811 kb on + strand, within kpsMat 2369.900 kb on - strand, within kpsMat 2369.933 kb on + strand, within kpsMat 2369.933 kb on + strand, within kpsMat 2370.046 kb on - strand, within kpsMat 2370.054 kb on + strand, within kpsMat 2370.058 kb on + strand, within kpsMat 2370.059 kb on - strand, within kpsMat 2370.059 kb on - strand, within kpsMat 2370.074 kb on - strand, within kpsMat 2370.074 kb on - strand, within kpsMat 2370.107 kb on + strand, within kpsMat 2370.144 kb on + strand, within kpsMat 2370.144 kb on + strand, within kpsMat 2370.320 kb on - strand, within kpsTat 2370.385 kb on - strand, within kpsTat 2370.385 kb on - strand, within kpsTat 2370.422 kb on - strand, within kpsTat 2371.265 kb on + strand, within neuDat 2371.367 kb on + strand, within neuDat 2371.425 kb on - strand, within neuDat 2371.506 kb on - strandat 2371.563 kb on + strandat 2371.565 kb on + strandat 2371.784 kb on + strand, within neuB

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Per-strain Table

Position Strand Gene LocusTag Fraction Sodium-DL-Lactate
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2,369,390 - +0.2
2,369,421 + +1.2
2,369,621 + kpsM HEPCGN_18100 0.22 +0.2
2,369,684 + kpsM HEPCGN_18100 0.30 -0.8
2,369,685 - kpsM HEPCGN_18100 0.30 -2.1
2,369,702 + kpsM HEPCGN_18100 0.32 -1.8
2,369,711 + kpsM HEPCGN_18100 0.33 +0.4
2,369,762 + kpsM HEPCGN_18100 0.40 -0.2
2,369,811 + kpsM HEPCGN_18100 0.46 +0.6
2,369,900 - kpsM HEPCGN_18100 0.58 +0.1
2,369,933 + kpsM HEPCGN_18100 0.62 -2.0
2,369,933 + kpsM HEPCGN_18100 0.62 -1.1
2,370,046 - kpsM HEPCGN_18100 0.77 -0.1
2,370,054 + kpsM HEPCGN_18100 0.78 +0.3
2,370,058 + kpsM HEPCGN_18100 0.78 -2.7
2,370,059 - kpsM HEPCGN_18100 0.78 +0.9
2,370,059 - kpsM HEPCGN_18100 0.78 -0.2
2,370,074 - kpsM HEPCGN_18100 0.80 +1.0
2,370,074 - kpsM HEPCGN_18100 0.80 +0.3
2,370,107 + kpsM HEPCGN_18100 0.84 -0.2
2,370,144 + kpsM HEPCGN_18100 0.89 -0.1
2,370,144 + kpsM HEPCGN_18100 0.89 +0.2
2,370,320 - kpsT HEPCGN_18105 0.15 +0.8
2,370,385 - kpsT HEPCGN_18105 0.24 -0.5
2,370,385 - kpsT HEPCGN_18105 0.24 -0.3
2,370,422 - kpsT HEPCGN_18105 0.30 +0.6
2,371,265 + neuD HEPCGN_18110 0.53 +0.7
2,371,367 + neuD HEPCGN_18110 0.70 +0.6
2,371,425 - neuD HEPCGN_18110 0.79 +1.1
2,371,506 - +0.7
2,371,563 + +0.6
2,371,565 + +0.2
2,371,784 + neuB HEPCGN_18115 0.22 +0.4

Or see this region's nucleotide sequence