Strain Fitness in Escherichia coli ECRC100 around OKFHMN_24505

Experiment: Sodium-DL-Lactate

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 nthisA and hisH overlap by 1 nucleotideshisH and hisB overlap by 1 nucleotideshisB and hisC overlap by 1 nucleotides OKFHMN_24495: hisA - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)me thylideneamino]imidazole-4-carboxamide isomerase, at 4,787,867 to 4,788,604 hisA OKFHMN_24500: hisH - imidazole glycerol phosphate synthase subunit HisH, at 4,788,604 to 4,789,194 hisH OKFHMN_24505: hisB - bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB, at 4,789,194 to 4,790,261 hisB OKFHMN_24510: hisC - histidinol-phosphate transaminase, at 4,790,261 to 4,791,331 hisC Position (kb) 4789 4790 4791Strain fitness (log2 ratio) -5 -4 -3 -2 -1 0 1at 4788.723 kb on + strand, within hisHat 4788.724 kb on - strand, within hisHat 4788.849 kb on + strand, within hisHat 4789.285 kb on - strandat 4789.304 kb on + strand, within hisBat 4789.343 kb on - strand, within hisBat 4789.534 kb on - strand, within hisBat 4789.742 kb on + strand, within hisBat 4789.742 kb on + strand, within hisBat 4789.885 kb on + strand, within hisBat 4790.026 kb on - strand, within hisBat 4790.436 kb on + strand, within hisCat 4790.546 kb on - strand, within hisCat 4790.657 kb on - strand, within hisCat 4790.772 kb on + strand, within hisCat 4790.773 kb on - strand, within hisCat 4790.995 kb on - strand, within hisCat 4791.191 kb on - strand, within hisC

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction Sodium-DL-Lactate
remove
4,788,723 + hisH OKFHMN_24500 0.20 -2.8
4,788,724 - hisH OKFHMN_24500 0.20 -2.0
4,788,849 + hisH OKFHMN_24500 0.41 -2.4
4,789,285 - -4.8
4,789,304 + hisB OKFHMN_24505 0.10 -2.9
4,789,343 - hisB OKFHMN_24505 0.14 -1.8
4,789,534 - hisB OKFHMN_24505 0.32 -0.2
4,789,742 + hisB OKFHMN_24505 0.51 -3.6
4,789,742 + hisB OKFHMN_24505 0.51 -3.1
4,789,885 + hisB OKFHMN_24505 0.65 -3.8
4,790,026 - hisB OKFHMN_24505 0.78 -2.0
4,790,436 + hisC OKFHMN_24510 0.16 -2.5
4,790,546 - hisC OKFHMN_24510 0.27 -4.1
4,790,657 - hisC OKFHMN_24510 0.37 -2.1
4,790,772 + hisC OKFHMN_24510 0.48 -2.6
4,790,773 - hisC OKFHMN_24510 0.48 -3.3
4,790,995 - hisC OKFHMN_24510 0.69 -2.0
4,791,191 - hisC OKFHMN_24510 0.87 -4.0

Or see this region's nucleotide sequence