Strain Fitness in Escherichia coli ECRC101 around MCAODC_20430

Experiment: WM_Bas09

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 nthisD and hisC overlap by 4 nucleotideshisC and hisB overlap by 1 nucleotides MCAODC_20425: hisD - Histidinol dehydrogenase, at 891,052 to 892,356 hisD MCAODC_20430: hisC - histidinol-phosphate transaminase, at 892,353 to 893,423 hisC MCAODC_20435: hisB - bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB, at 893,423 to 894,490 hisB Position (kb) 892 893 894Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 891.372 kb on - strand, within hisDat 891.377 kb on + strand, within hisDat 891.377 kb on + strand, within hisDat 891.377 kb on + strand, within hisDat 891.378 kb on - strand, within hisDat 891.439 kb on + strand, within hisDat 891.440 kb on - strand, within hisDat 891.440 kb on - strand, within hisDat 891.440 kb on - strand, within hisDat 891.476 kb on + strand, within hisDat 891.477 kb on - strand, within hisDat 891.479 kb on + strand, within hisDat 891.480 kb on - strand, within hisDat 891.502 kb on - strand, within hisDat 892.094 kb on + strand, within hisDat 892.094 kb on + strand, within hisDat 892.166 kb on - strand, within hisDat 892.320 kb on + strandat 892.321 kb on - strandat 892.342 kb on - strandat 892.367 kb on + strandat 892.367 kb on + strandat 892.378 kb on + strandat 892.468 kb on - strand, within hisCat 892.494 kb on - strand, within hisCat 892.560 kb on + strand, within hisCat 892.561 kb on - strand, within hisCat 892.614 kb on - strand, within hisCat 892.614 kb on - strand, within hisCat 892.680 kb on + strand, within hisCat 892.762 kb on + strand, within hisCat 892.763 kb on - strand, within hisCat 892.803 kb on + strand, within hisCat 892.804 kb on - strand, within hisCat 892.911 kb on + strand, within hisCat 892.912 kb on - strand, within hisCat 892.912 kb on - strand, within hisCat 892.912 kb on - strand, within hisCat 892.912 kb on - strand, within hisCat 892.912 kb on - strand, within hisCat 892.973 kb on + strand, within hisCat 893.027 kb on + strand, within hisCat 893.027 kb on + strand, within hisCat 893.028 kb on - strand, within hisCat 893.028 kb on - strand, within hisCat 893.168 kb on + strand, within hisCat 893.247 kb on + strand, within hisCat 893.248 kb on - strand, within hisCat 893.248 kb on - strand, within hisCat 893.310 kb on - strand, within hisCat 893.405 kb on - strandat 893.677 kb on - strand, within hisBat 893.798 kb on + strand, within hisBat 893.798 kb on + strand, within hisBat 893.941 kb on + strand, within hisBat 893.945 kb on - strand, within hisBat 894.004 kb on + strand, within hisBat 894.263 kb on + strand, within hisBat 894.265 kb on + strand, within hisBat 894.266 kb on - strand, within hisBat 894.341 kb on + strand, within hisBat 894.341 kb on + strand, within hisBat 894.341 kb on + strand, within hisBat 894.342 kb on - strand, within hisBat 894.379 kb on + strand, within hisBat 894.400 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction WM_Bas09
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891,372 - hisD MCAODC_20425 0.25 -2.8
891,377 + hisD MCAODC_20425 0.25 -1.1
891,377 + hisD MCAODC_20425 0.25 -1.3
891,377 + hisD MCAODC_20425 0.25 +0.4
891,378 - hisD MCAODC_20425 0.25 -1.3
891,439 + hisD MCAODC_20425 0.30 -1.4
891,440 - hisD MCAODC_20425 0.30 -1.2
891,440 - hisD MCAODC_20425 0.30 -0.4
891,440 - hisD MCAODC_20425 0.30 -1.4
891,476 + hisD MCAODC_20425 0.32 -0.7
891,477 - hisD MCAODC_20425 0.33 -0.8
891,479 + hisD MCAODC_20425 0.33 -0.7
891,480 - hisD MCAODC_20425 0.33 -0.4
891,502 - hisD MCAODC_20425 0.34 +0.6
892,094 + hisD MCAODC_20425 0.80 -1.9
892,094 + hisD MCAODC_20425 0.80 -2.3
892,166 - hisD MCAODC_20425 0.85 +0.1
892,320 + -0.1
892,321 - -0.3
892,342 - +0.9
892,367 + -2.8
892,367 + +0.2
892,378 + -1.1
892,468 - hisC MCAODC_20430 0.11 -0.7
892,494 - hisC MCAODC_20430 0.13 +0.9
892,560 + hisC MCAODC_20430 0.19 +0.3
892,561 - hisC MCAODC_20430 0.19 -2.7
892,614 - hisC MCAODC_20430 0.24 -1.8
892,614 - hisC MCAODC_20430 0.24 -0.3
892,680 + hisC MCAODC_20430 0.31 -1.0
892,762 + hisC MCAODC_20430 0.38 +2.6
892,763 - hisC MCAODC_20430 0.38 +1.4
892,803 + hisC MCAODC_20430 0.42 -0.8
892,804 - hisC MCAODC_20430 0.42 +0.0
892,911 + hisC MCAODC_20430 0.52 +1.1
892,912 - hisC MCAODC_20430 0.52 -1.9
892,912 - hisC MCAODC_20430 0.52 +0.2
892,912 - hisC MCAODC_20430 0.52 -0.4
892,912 - hisC MCAODC_20430 0.52 -2.1
892,912 - hisC MCAODC_20430 0.52 -0.4
892,973 + hisC MCAODC_20430 0.58 +0.2
893,027 + hisC MCAODC_20430 0.63 -1.2
893,027 + hisC MCAODC_20430 0.63 -0.6
893,028 - hisC MCAODC_20430 0.63 -1.4
893,028 - hisC MCAODC_20430 0.63 -1.8
893,168 + hisC MCAODC_20430 0.76 +0.8
893,247 + hisC MCAODC_20430 0.83 -1.7
893,248 - hisC MCAODC_20430 0.84 -0.4
893,248 - hisC MCAODC_20430 0.84 -0.6
893,310 - hisC MCAODC_20430 0.89 -2.8
893,405 - -1.3
893,677 - hisB MCAODC_20435 0.24 -0.6
893,798 + hisB MCAODC_20435 0.35 +0.6
893,798 + hisB MCAODC_20435 0.35 -1.4
893,941 + hisB MCAODC_20435 0.49 -0.0
893,945 - hisB MCAODC_20435 0.49 -1.7
894,004 + hisB MCAODC_20435 0.54 -0.9
894,263 + hisB MCAODC_20435 0.79 -3.3
894,265 + hisB MCAODC_20435 0.79 -1.8
894,266 - hisB MCAODC_20435 0.79 -0.3
894,341 + hisB MCAODC_20435 0.86 -0.2
894,341 + hisB MCAODC_20435 0.86 -0.4
894,341 + hisB MCAODC_20435 0.86 +0.6
894,342 - hisB MCAODC_20435 0.86 -2.6
894,379 + hisB MCAODC_20435 0.90 -2.3
894,400 - -2.6

Or see this region's nucleotide sequence