Strain Fitness in Escherichia coli ECRC102 around NIAGMN_18435

Experiment: Sodium-DL-Lactate

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntgutQ and srlR overlap by 8 nucleotidessrlR and gutM are separated by 66 nucleotidesgutM and srlD are separated by 105 nucleotidessrlD and srlB are separated by 3 nucleotides NIAGMN_18425: gutQ - arabinose-5-phosphate isomerase GutQ, at 3,646,967 to 3,647,932 gutQ NIAGMN_18430: srlR - glucitol operon DNA-binding transcriptional repressor SrlR, at 3,647,925 to 3,648,698 srlR NIAGMN_18435: gutM - transcriptional regulator GutM, at 3,648,765 to 3,649,124 gutM NIAGMN_18440: srlD - sorbitol-6-phosphate dehydrogenase, at 3,649,230 to 3,650,009 srlD NIAGMN_18445: srlB - PTS glucitol/sorbitol transporter subunit IIA, at 3,650,013 to 3,650,384 srlB Position (kb) 3648 3649 3650Strain fitness (log2 ratio) -3 -2 -1 0 1 2 3at 3647.918 kb on + strandat 3647.919 kb on - strandat 3647.947 kb on - strandat 3648.045 kb on + strand, within srlRat 3648.045 kb on + strand, within srlRat 3648.045 kb on + strand, within srlRat 3648.046 kb on - strand, within srlRat 3648.046 kb on - strand, within srlRat 3648.046 kb on - strand, within srlRat 3648.122 kb on + strand, within srlRat 3648.133 kb on + strand, within srlRat 3648.133 kb on + strand, within srlRat 3648.134 kb on - strand, within srlRat 3648.134 kb on - strand, within srlRat 3648.134 kb on - strand, within srlRat 3648.134 kb on - strand, within srlRat 3648.134 kb on - strand, within srlRat 3648.134 kb on - strand, within srlRat 3648.134 kb on - strand, within srlRat 3648.134 kb on - strand, within srlRat 3648.287 kb on + strand, within srlRat 3648.357 kb on - strand, within srlRat 3648.359 kb on + strand, within srlRat 3648.435 kb on - strand, within srlRat 3648.435 kb on - strand, within srlRat 3648.435 kb on - strand, within srlRat 3648.456 kb on + strand, within srlRat 3648.456 kb on + strand, within srlRat 3648.491 kb on + strand, within srlRat 3648.542 kb on - strand, within srlRat 3648.542 kb on - strand, within srlRat 3648.545 kb on + strand, within srlRat 3648.546 kb on - strand, within srlRat 3648.546 kb on - strand, within srlRat 3648.546 kb on - strand, within srlRat 3648.546 kb on - strand, within srlRat 3648.594 kb on - strand, within srlRat 3648.594 kb on - strand, within srlRat 3648.662 kb on - strandat 3648.662 kb on - strandat 3648.766 kb on + strandat 3648.796 kb on - strandat 3648.866 kb on + strand, within gutMat 3648.866 kb on + strand, within gutMat 3648.866 kb on + strand, within gutMat 3648.866 kb on + strand, within gutMat 3648.867 kb on - strand, within gutMat 3648.915 kb on - strand, within gutMat 3649.023 kb on + strand, within gutMat 3649.023 kb on + strand, within gutMat 3649.024 kb on - strand, within gutMat 3649.024 kb on - strand, within gutMat 3649.024 kb on - strand, within gutMat 3649.024 kb on - strand, within gutMat 3649.124 kb on + strandat 3649.124 kb on + strandat 3649.125 kb on - strandat 3649.135 kb on + strandat 3649.136 kb on - strandat 3649.140 kb on + strandat 3649.141 kb on - strandat 3649.157 kb on + strandat 3649.157 kb on + strandat 3649.158 kb on - strandat 3649.189 kb on + strandat 3649.190 kb on - strandat 3649.190 kb on - strandat 3649.193 kb on - strandat 3649.193 kb on - strandat 3649.289 kb on + strandat 3649.300 kb on + strandat 3649.301 kb on - strandat 3649.301 kb on - strandat 3649.301 kb on - strandat 3649.314 kb on - strand, within srlDat 3649.314 kb on - strand, within srlDat 3649.314 kb on - strand, within srlDat 3649.366 kb on + strand, within srlDat 3649.367 kb on - strand, within srlDat 3649.367 kb on - strand, within srlDat 3649.367 kb on - strand, within srlDat 3649.367 kb on - strand, within srlDat 3649.367 kb on - strand, within srlDat 3649.367 kb on - strand, within srlDat 3649.367 kb on - strand, within srlDat 3649.369 kb on + strand, within srlDat 3649.369 kb on + strand, within srlDat 3649.412 kb on - strand, within srlDat 3649.479 kb on - strand, within srlDat 3649.548 kb on - strand, within srlDat 3649.664 kb on - strand, within srlDat 3649.750 kb on + strand, within srlDat 3649.751 kb on - strand, within srlDat 3649.751 kb on - strand, within srlDat 3649.759 kb on - strand, within srlDat 3649.786 kb on - strand, within srlDat 3649.843 kb on + strand, within srlDat 3649.844 kb on - strand, within srlDat 3649.844 kb on - strand, within srlDat 3649.844 kb on - strand, within srlDat 3649.844 kb on - strand, within srlDat 3649.968 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction Sodium-DL-Lactate
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3,647,918 + -0.2
3,647,919 - +0.8
3,647,947 - +1.3
3,648,045 + srlR NIAGMN_18430 0.16 +2.0
3,648,045 + srlR NIAGMN_18430 0.16 -0.5
3,648,045 + srlR NIAGMN_18430 0.16 -0.9
3,648,046 - srlR NIAGMN_18430 0.16 -0.4
3,648,046 - srlR NIAGMN_18430 0.16 -0.6
3,648,046 - srlR NIAGMN_18430 0.16 +0.5
3,648,122 + srlR NIAGMN_18430 0.25 +0.5
3,648,133 + srlR NIAGMN_18430 0.27 +0.4
3,648,133 + srlR NIAGMN_18430 0.27 -1.7
3,648,134 - srlR NIAGMN_18430 0.27 +0.3
3,648,134 - srlR NIAGMN_18430 0.27 -1.3
3,648,134 - srlR NIAGMN_18430 0.27 +0.3
3,648,134 - srlR NIAGMN_18430 0.27 -0.5
3,648,134 - srlR NIAGMN_18430 0.27 -0.4
3,648,134 - srlR NIAGMN_18430 0.27 +1.2
3,648,134 - srlR NIAGMN_18430 0.27 -0.4
3,648,134 - srlR NIAGMN_18430 0.27 -1.0
3,648,287 + srlR NIAGMN_18430 0.47 +0.3
3,648,357 - srlR NIAGMN_18430 0.56 -0.3
3,648,359 + srlR NIAGMN_18430 0.56 +0.4
3,648,435 - srlR NIAGMN_18430 0.66 +0.2
3,648,435 - srlR NIAGMN_18430 0.66 +1.2
3,648,435 - srlR NIAGMN_18430 0.66 +0.4
3,648,456 + srlR NIAGMN_18430 0.69 +0.2
3,648,456 + srlR NIAGMN_18430 0.69 -2.3
3,648,491 + srlR NIAGMN_18430 0.73 -2.1
3,648,542 - srlR NIAGMN_18430 0.80 -0.9
3,648,542 - srlR NIAGMN_18430 0.80 +0.7
3,648,545 + srlR NIAGMN_18430 0.80 -1.9
3,648,546 - srlR NIAGMN_18430 0.80 +1.0
3,648,546 - srlR NIAGMN_18430 0.80 -1.2
3,648,546 - srlR NIAGMN_18430 0.80 +0.0
3,648,546 - srlR NIAGMN_18430 0.80 +0.4
3,648,594 - srlR NIAGMN_18430 0.86 +0.6
3,648,594 - srlR NIAGMN_18430 0.86 -2.5
3,648,662 - +0.8
3,648,662 - +0.5
3,648,766 + -0.3
3,648,796 - -2.2
3,648,866 + gutM NIAGMN_18435 0.28 +0.0
3,648,866 + gutM NIAGMN_18435 0.28 +1.0
3,648,866 + gutM NIAGMN_18435 0.28 -0.1
3,648,866 + gutM NIAGMN_18435 0.28 +0.7
3,648,867 - gutM NIAGMN_18435 0.28 +0.4
3,648,915 - gutM NIAGMN_18435 0.42 -1.0
3,649,023 + gutM NIAGMN_18435 0.72 +0.5
3,649,023 + gutM NIAGMN_18435 0.72 +1.3
3,649,024 - gutM NIAGMN_18435 0.72 -2.1
3,649,024 - gutM NIAGMN_18435 0.72 -0.1
3,649,024 - gutM NIAGMN_18435 0.72 -0.2
3,649,024 - gutM NIAGMN_18435 0.72 +1.5
3,649,124 + +0.1
3,649,124 + -0.8
3,649,125 - -0.6
3,649,135 + +0.4
3,649,136 - -0.1
3,649,140 + -0.5
3,649,141 - -0.1
3,649,157 + -0.8
3,649,157 + -0.9
3,649,158 - +1.5
3,649,189 + -1.8
3,649,190 - +1.3
3,649,190 - -0.8
3,649,193 - -2.9
3,649,193 - +1.4
3,649,289 + +1.3
3,649,300 + +0.2
3,649,301 - -0.3
3,649,301 - -1.9
3,649,301 - +0.2
3,649,314 - srlD NIAGMN_18440 0.11 -0.3
3,649,314 - srlD NIAGMN_18440 0.11 -0.1
3,649,314 - srlD NIAGMN_18440 0.11 -1.0
3,649,366 + srlD NIAGMN_18440 0.17 -0.5
3,649,367 - srlD NIAGMN_18440 0.18 -1.0
3,649,367 - srlD NIAGMN_18440 0.18 +2.1
3,649,367 - srlD NIAGMN_18440 0.18 -0.9
3,649,367 - srlD NIAGMN_18440 0.18 -0.4
3,649,367 - srlD NIAGMN_18440 0.18 -0.5
3,649,367 - srlD NIAGMN_18440 0.18 -0.8
3,649,367 - srlD NIAGMN_18440 0.18 -0.4
3,649,369 + srlD NIAGMN_18440 0.18 +0.3
3,649,369 + srlD NIAGMN_18440 0.18 +2.9
3,649,412 - srlD NIAGMN_18440 0.23 +0.3
3,649,479 - srlD NIAGMN_18440 0.32 +0.3
3,649,548 - srlD NIAGMN_18440 0.41 +2.1
3,649,664 - srlD NIAGMN_18440 0.56 -1.2
3,649,750 + srlD NIAGMN_18440 0.67 -0.0
3,649,751 - srlD NIAGMN_18440 0.67 +3.4
3,649,751 - srlD NIAGMN_18440 0.67 +0.5
3,649,759 - srlD NIAGMN_18440 0.68 -0.3
3,649,786 - srlD NIAGMN_18440 0.71 -0.3
3,649,843 + srlD NIAGMN_18440 0.79 -0.9
3,649,844 - srlD NIAGMN_18440 0.79 +0.1
3,649,844 - srlD NIAGMN_18440 0.79 +1.2
3,649,844 - srlD NIAGMN_18440 0.79 -0.2
3,649,844 - srlD NIAGMN_18440 0.79 +1.7
3,649,968 + -1.4

Or see this region's nucleotide sequence