Experiment: Sodium-DL-Lactate
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt polB and rapA are separated by 163 nucleotides rapA and rluA are separated by 11 nucleotides
MCAODC_01310: polB - DNA polymerase II, at 246,499 to 248,850
polB
MCAODC_01315: rapA - RNA polymerase-associated protein RapA, at 249,014 to 251,920
rapA
MCAODC_01320: rluA - bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA, at 251,932 to 252,591
rluA
Position (kb) 249
250
251
252 Strain fitness (log2 ratio) -4
-3
-2
-1
0
1
2
3 at 248.126 kb on - strand, within polB at 248.278 kb on + strand, within polB at 248.455 kb on + strand, within polB at 248.456 kb on - strand, within polB at 248.456 kb on - strand, within polB at 248.456 kb on - strand, within polB at 248.463 kb on + strand, within polB at 248.464 kb on - strand, within polB at 248.492 kb on - strand, within polB at 248.492 kb on - strand, within polB at 248.589 kb on + strand, within polB at 248.590 kb on - strand, within polB at 248.590 kb on - strand, within polB at 248.606 kb on + strand, within polB at 248.606 kb on + strand, within polB at 248.607 kb on - strand, within polB at 248.607 kb on - strand, within polB at 248.662 kb on + strand at 248.682 kb on + strand at 248.682 kb on + strand at 248.683 kb on - strand at 248.683 kb on - strand at 248.686 kb on + strand at 248.686 kb on + strand at 248.687 kb on - strand at 248.687 kb on - strand at 248.687 kb on - strand at 248.687 kb on - strand at 248.690 kb on + strand at 248.690 kb on + strand at 248.690 kb on + strand at 248.690 kb on + strand at 248.690 kb on + strand at 248.690 kb on + strand at 248.690 kb on + strand at 248.691 kb on - strand at 248.691 kb on - strand at 248.723 kb on - strand at 248.743 kb on + strand at 248.752 kb on + strand at 248.752 kb on + strand at 248.752 kb on + strand at 248.753 kb on - strand at 248.768 kb on + strand at 248.768 kb on + strand at 248.769 kb on - strand at 248.789 kb on + strand at 248.789 kb on + strand at 248.789 kb on + strand at 248.817 kb on + strand at 248.818 kb on - strand at 248.823 kb on + strand at 248.823 kb on + strand at 248.823 kb on + strand at 248.823 kb on + strand at 248.824 kb on - strand at 248.824 kb on - strand at 248.824 kb on - strand at 248.824 kb on - strand at 248.824 kb on - strand at 248.824 kb on - strand at 248.909 kb on + strand at 248.909 kb on + strand at 248.910 kb on - strand at 248.958 kb on + strand at 248.958 kb on + strand at 248.958 kb on + strand at 248.958 kb on + strand at 248.958 kb on + strand at 248.959 kb on - strand at 248.978 kb on + strand at 248.991 kb on + strand at 248.992 kb on - strand at 248.992 kb on - strand at 248.997 kb on + strand at 248.997 kb on + strand at 248.999 kb on + strand at 248.999 kb on + strand at 249.000 kb on - strand at 249.000 kb on - strand at 249.000 kb on - strand at 249.013 kb on + strand at 249.013 kb on + strand at 249.013 kb on + strand at 249.014 kb on - strand at 249.014 kb on - strand at 249.023 kb on - strand at 249.023 kb on - strand at 249.023 kb on - strand at 249.121 kb on + strand at 249.121 kb on + strand at 249.121 kb on + strand at 249.122 kb on - strand at 249.234 kb on + strand at 249.235 kb on - strand at 249.235 kb on - strand at 249.260 kb on + strand at 249.260 kb on + strand at 249.261 kb on - strand at 249.261 kb on - strand at 249.322 kb on + strand, within rapA at 249.322 kb on + strand, within rapA at 249.413 kb on - strand, within rapA at 249.413 kb on - strand, within rapA at 249.416 kb on + strand, within rapA at 249.444 kb on - strand, within rapA at 249.646 kb on - strand, within rapA at 249.663 kb on + strand, within rapA at 249.740 kb on + strand, within rapA at 249.740 kb on + strand, within rapA at 249.740 kb on + strand, within rapA at 249.740 kb on + strand, within rapA at 249.740 kb on + strand, within rapA at 249.740 kb on + strand, within rapA at 249.741 kb on - strand, within rapA at 249.741 kb on - strand, within rapA at 249.741 kb on - strand, within rapA at 249.907 kb on + strand, within rapA at 249.907 kb on + strand, within rapA at 250.355 kb on - strand, within rapA at 250.358 kb on - strand, within rapA at 250.429 kb on + strand, within rapA at 250.578 kb on + strand, within rapA at 250.579 kb on - strand, within rapA at 250.598 kb on - strand, within rapA at 250.624 kb on + strand, within rapA at 250.625 kb on - strand, within rapA at 250.625 kb on - strand, within rapA at 250.625 kb on - strand, within rapA at 250.625 kb on - strand, within rapA at 250.690 kb on - strand, within rapA at 250.723 kb on + strand, within rapA at 250.723 kb on + strand, within rapA at 250.723 kb on + strand, within rapA at 250.724 kb on - strand, within rapA at 250.724 kb on - strand, within rapA at 250.792 kb on + strand, within rapA at 250.811 kb on - strand, within rapA at 250.847 kb on + strand, within rapA at 250.847 kb on + strand, within rapA at 250.887 kb on - strand, within rapA at 250.936 kb on + strand, within rapA at 250.940 kb on + strand, within rapA at 250.940 kb on + strand, within rapA at 250.941 kb on - strand, within rapA at 250.941 kb on - strand, within rapA at 250.941 kb on - strand, within rapA at 250.950 kb on + strand, within rapA at 250.950 kb on + strand, within rapA at 250.950 kb on + strand, within rapA at 250.950 kb on + strand, within rapA at 250.950 kb on + strand, within rapA at 250.951 kb on - strand, within rapA at 250.952 kb on + strand, within rapA at 250.952 kb on + strand, within rapA at 250.952 kb on + strand, within rapA at 250.953 kb on - strand, within rapA at 250.966 kb on + strand, within rapA at 250.967 kb on - strand, within rapA at 250.970 kb on + strand, within rapA at 250.970 kb on + strand, within rapA at 250.970 kb on + strand, within rapA at 250.971 kb on - strand, within rapA at 250.971 kb on - strand, within rapA at 250.971 kb on - strand, within rapA at 251.248 kb on + strand, within rapA at 251.248 kb on + strand, within rapA at 251.249 kb on - strand, within rapA at 251.342 kb on - strand, within rapA at 251.344 kb on + strand, within rapA at 251.344 kb on + strand, within rapA at 251.471 kb on + strand, within rapA at 251.471 kb on + strand, within rapA at 251.539 kb on + strand, within rapA at 251.539 kb on + strand, within rapA at 251.539 kb on + strand, within rapA at 251.539 kb on + strand, within rapA at 251.539 kb on + strand, within rapA at 251.540 kb on - strand, within rapA at 251.540 kb on - strand, within rapA at 251.540 kb on - strand, within rapA at 251.540 kb on - strand, within rapA at 251.540 kb on - strand, within rapA at 251.540 kb on - strand, within rapA at 251.608 kb on + strand, within rapA at 251.608 kb on + strand, within rapA at 251.671 kb on + strand at 251.850 kb on + strand at 251.850 kb on + strand at 251.850 kb on + strand at 251.850 kb on + strand at 251.851 kb on - strand at 251.908 kb on - strand at 251.919 kb on - strand at 251.976 kb on + strand at 251.983 kb on + strand at 251.984 kb on - strand at 251.997 kb on + strand at 251.997 kb on + strand at 251.997 kb on + strand at 251.997 kb on + strand at 251.998 kb on - strand, within rluA at 251.998 kb on - strand, within rluA at 251.998 kb on - strand, within rluA at 251.998 kb on - strand, within rluA at 251.998 kb on - strand, within rluA at 252.000 kb on + strand, within rluA at 252.001 kb on - strand, within rluA at 252.001 kb on - strand, within rluA at 252.001 kb on - strand, within rluA at 252.147 kb on - strand, within rluA at 252.179 kb on + strand, within rluA at 252.179 kb on + strand, within rluA at 252.217 kb on + strand, within rluA at 252.217 kb on + strand, within rluA at 252.218 kb on - strand, within rluA at 252.218 kb on - strand, within rluA at 252.218 kb on - strand, within rluA at 252.218 kb on - strand, within rluA at 252.316 kb on + strand, within rluA at 252.361 kb on + strand, within rluA at 252.362 kb on - strand, within rluA at 252.362 kb on - strand, within rluA at 252.433 kb on - strand, within rluA at 252.433 kb on - strand, within rluA at 252.473 kb on - strand, within rluA at 252.515 kb on + strand, within rluA at 252.515 kb on + strand, within rluA at 252.515 kb on + strand, within rluA at 252.516 kb on - strand, within rluA at 252.516 kb on - strand, within rluA at 252.551 kb on - strand at 252.558 kb on + strand at 252.558 kb on + strand at 252.558 kb on + strand at 252.558 kb on + strand at 252.558 kb on + strand at 252.559 kb on - strand at 252.561 kb on + strand at 252.562 kb on - strand at 252.571 kb on - strand at 252.607 kb on + strand at 252.607 kb on + strand at 252.607 kb on + strand at 252.610 kb on - strand at 252.610 kb on - strand at 252.621 kb on - strand at 252.636 kb on + strand at 252.640 kb on + strand at 252.640 kb on + strand at 252.640 kb on + strand at 252.640 kb on + strand at 252.640 kb on + strand at 252.640 kb on + strand at 252.641 kb on - strand at 252.641 kb on - strand at 252.641 kb on - strand at 252.641 kb on - strand at 252.641 kb on - strand at 252.641 kb on - strand at 252.702 kb on + strand at 252.779 kb on + strand at 252.779 kb on + strand at 252.779 kb on + strand at 252.780 kb on - strand at 252.781 kb on + strand at 252.782 kb on - strand at 252.804 kb on - strand at 252.823 kb on - strand at 252.834 kb on - strand at 252.838 kb on - strand at 252.879 kb on + strand at 252.899 kb on + strand at 252.911 kb on + strand at 252.912 kb on - strand at 252.912 kb on - strand at 252.912 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Sodium-DL-Lactate remove 248,126 - polB MCAODC_01310 0.69 +0.9 248,278 + polB MCAODC_01310 0.76 +0.8 248,455 + polB MCAODC_01310 0.83 +0.6 248,456 - polB MCAODC_01310 0.83 -0.1 248,456 - polB MCAODC_01310 0.83 +0.7 248,456 - polB MCAODC_01310 0.83 -1.1 248,463 + polB MCAODC_01310 0.84 +0.1 248,464 - polB MCAODC_01310 0.84 -0.3 248,492 - polB MCAODC_01310 0.85 +0.7 248,492 - polB MCAODC_01310 0.85 +0.4 248,589 + polB MCAODC_01310 0.89 -1.6 248,590 - polB MCAODC_01310 0.89 -0.8 248,590 - polB MCAODC_01310 0.89 +1.0 248,606 + polB MCAODC_01310 0.90 +0.2 248,606 + polB MCAODC_01310 0.90 -2.2 248,607 - polB MCAODC_01310 0.90 +0.6 248,607 - polB MCAODC_01310 0.90 -0.4 248,662 + +0.6 248,682 + +0.1 248,682 + -0.7 248,683 - +1.1 248,683 - +1.2 248,686 + +0.2 248,686 + +0.8 248,687 - +0.1 248,687 - -1.9 248,687 - +0.3 248,687 - +0.2 248,690 + +0.3 248,690 + -0.0 248,690 + +0.3 248,690 + -0.7 248,690 + +1.0 248,690 + -1.4 248,690 + +0.4 248,691 - -0.9 248,691 - +0.3 248,723 - -0.8 248,743 + +0.2 248,752 + -0.8 248,752 + +2.5 248,752 + -0.4 248,753 - +0.3 248,768 + +0.8 248,768 + -0.6 248,769 - -0.4 248,789 + +0.4 248,789 + -1.8 248,789 + +0.9 248,817 + +0.5 248,818 - -0.1 248,823 + -0.0 248,823 + +0.2 248,823 + +1.6 248,823 + +0.3 248,824 - +0.5 248,824 - -1.2 248,824 - +0.1 248,824 - -0.2 248,824 - +0.2 248,824 - +0.4 248,909 + +0.1 248,909 + +0.7 248,910 - -2.5 248,958 + +1.6 248,958 + -1.5 248,958 + +0.4 248,958 + -0.5 248,958 + +0.9 248,959 - -0.3 248,978 + -1.1 248,991 + -0.3 248,992 - -0.8 248,992 - +0.5 248,997 + +0.3 248,997 + +1.0 248,999 + +0.5 248,999 + +0.3 249,000 - +0.3 249,000 - +1.1 249,000 - +0.2 249,013 + -2.2 249,013 + -0.8 249,013 + -0.7 249,014 - -0.5 249,014 - +1.2 249,023 - -1.0 249,023 - -0.2 249,023 - -0.4 249,121 + -4.4 249,121 + +2.0 249,121 + -1.1 249,122 - +0.3 249,234 + -0.5 249,235 - +0.3 249,235 - -0.1 249,260 + -1.7 249,260 + +1.3 249,261 - +1.1 249,261 - -0.6 249,322 + rapA MCAODC_01315 0.11 -0.8 249,322 + rapA MCAODC_01315 0.11 -0.2 249,413 - rapA MCAODC_01315 0.14 +0.1 249,413 - rapA MCAODC_01315 0.14 +0.0 249,416 + rapA MCAODC_01315 0.14 +1.2 249,444 - rapA MCAODC_01315 0.15 -0.3 249,646 - rapA MCAODC_01315 0.22 -1.0 249,663 + rapA MCAODC_01315 0.22 -0.1 249,740 + rapA MCAODC_01315 0.25 -0.1 249,740 + rapA MCAODC_01315 0.25 -1.4 249,740 + rapA MCAODC_01315 0.25 -0.2 249,740 + rapA MCAODC_01315 0.25 +0.8 249,740 + rapA MCAODC_01315 0.25 +0.2 249,740 + rapA MCAODC_01315 0.25 +1.0 249,741 - rapA MCAODC_01315 0.25 -1.7 249,741 - rapA MCAODC_01315 0.25 +1.2 249,741 - rapA MCAODC_01315 0.25 -1.0 249,907 + rapA MCAODC_01315 0.31 -0.1 249,907 + rapA MCAODC_01315 0.31 +0.7 250,355 - rapA MCAODC_01315 0.46 +2.9 250,358 - rapA MCAODC_01315 0.46 -1.5 250,429 + rapA MCAODC_01315 0.49 -1.0 250,578 + rapA MCAODC_01315 0.54 -2.7 250,579 - rapA MCAODC_01315 0.54 +1.0 250,598 - rapA MCAODC_01315 0.54 +1.1 250,624 + rapA MCAODC_01315 0.55 -0.1 250,625 - rapA MCAODC_01315 0.55 -0.1 250,625 - rapA MCAODC_01315 0.55 -1.4 250,625 - rapA MCAODC_01315 0.55 -0.9 250,625 - rapA MCAODC_01315 0.55 +1.1 250,690 - rapA MCAODC_01315 0.58 +1.2 250,723 + rapA MCAODC_01315 0.59 -0.4 250,723 + rapA MCAODC_01315 0.59 -0.2 250,723 + rapA MCAODC_01315 0.59 -0.0 250,724 - rapA MCAODC_01315 0.59 -1.4 250,724 - rapA MCAODC_01315 0.59 -2.7 250,792 + rapA MCAODC_01315 0.61 -0.3 250,811 - rapA MCAODC_01315 0.62 -0.7 250,847 + rapA MCAODC_01315 0.63 -0.1 250,847 + rapA MCAODC_01315 0.63 +0.4 250,887 - rapA MCAODC_01315 0.64 -0.2 250,936 + rapA MCAODC_01315 0.66 -1.1 250,940 + rapA MCAODC_01315 0.66 -0.5 250,940 + rapA MCAODC_01315 0.66 -0.5 250,941 - rapA MCAODC_01315 0.66 -0.2 250,941 - rapA MCAODC_01315 0.66 -1.1 250,941 - rapA MCAODC_01315 0.66 +0.3 250,950 + rapA MCAODC_01315 0.67 +0.9 250,950 + rapA MCAODC_01315 0.67 -0.2 250,950 + rapA MCAODC_01315 0.67 +0.4 250,950 + rapA MCAODC_01315 0.67 +0.1 250,950 + rapA MCAODC_01315 0.67 +1.1 250,951 - rapA MCAODC_01315 0.67 -0.2 250,952 + rapA MCAODC_01315 0.67 -1.2 250,952 + rapA MCAODC_01315 0.67 -0.2 250,952 + rapA MCAODC_01315 0.67 +0.8 250,953 - rapA MCAODC_01315 0.67 +0.6 250,966 + rapA MCAODC_01315 0.67 -0.6 250,967 - rapA MCAODC_01315 0.67 +0.6 250,970 + rapA MCAODC_01315 0.67 +1.8 250,970 + rapA MCAODC_01315 0.67 +0.2 250,970 + rapA MCAODC_01315 0.67 -1.0 250,971 - rapA MCAODC_01315 0.67 +0.8 250,971 - rapA MCAODC_01315 0.67 -0.6 250,971 - rapA MCAODC_01315 0.67 -0.8 251,248 + rapA MCAODC_01315 0.77 +0.2 251,248 + rapA MCAODC_01315 0.77 +0.1 251,249 - rapA MCAODC_01315 0.77 +0.8 251,342 - rapA MCAODC_01315 0.80 -2.4 251,344 + rapA MCAODC_01315 0.80 -0.1 251,344 + rapA MCAODC_01315 0.80 +0.3 251,471 + rapA MCAODC_01315 0.85 -3.2 251,471 + rapA MCAODC_01315 0.85 +0.7 251,539 + rapA MCAODC_01315 0.87 -1.7 251,539 + rapA MCAODC_01315 0.87 +0.1 251,539 + rapA MCAODC_01315 0.87 -0.5 251,539 + rapA MCAODC_01315 0.87 -0.3 251,539 + rapA MCAODC_01315 0.87 -0.2 251,540 - rapA MCAODC_01315 0.87 -0.7 251,540 - rapA MCAODC_01315 0.87 -0.8 251,540 - rapA MCAODC_01315 0.87 -2.2 251,540 - rapA MCAODC_01315 0.87 +0.1 251,540 - rapA MCAODC_01315 0.87 -1.4 251,540 - rapA MCAODC_01315 0.87 +1.2 251,608 + rapA MCAODC_01315 0.89 -0.2 251,608 + rapA MCAODC_01315 0.89 +0.3 251,671 + -0.1 251,850 + -0.1 251,850 + +2.1 251,850 + +0.4 251,850 + -0.2 251,851 - +0.5 251,908 - -0.5 251,919 - -0.1 251,976 + -0.4 251,983 + -1.8 251,984 - -0.2 251,997 + -0.0 251,997 + +0.6 251,997 + +0.6 251,997 + +0.7 251,998 - rluA MCAODC_01320 0.10 -1.6 251,998 - rluA MCAODC_01320 0.10 -0.4 251,998 - rluA MCAODC_01320 0.10 -0.1 251,998 - rluA MCAODC_01320 0.10 +0.7 251,998 - rluA MCAODC_01320 0.10 -0.3 252,000 + rluA MCAODC_01320 0.10 -3.2 252,001 - rluA MCAODC_01320 0.10 -0.5 252,001 - rluA MCAODC_01320 0.10 +1.5 252,001 - rluA MCAODC_01320 0.10 +1.3 252,147 - rluA MCAODC_01320 0.33 +1.6 252,179 + rluA MCAODC_01320 0.37 -0.4 252,179 + rluA MCAODC_01320 0.37 +0.3 252,217 + rluA MCAODC_01320 0.43 -0.2 252,217 + rluA MCAODC_01320 0.43 -1.1 252,218 - rluA MCAODC_01320 0.43 +0.0 252,218 - rluA MCAODC_01320 0.43 +0.0 252,218 - rluA MCAODC_01320 0.43 +1.0 252,218 - rluA MCAODC_01320 0.43 +1.0 252,316 + rluA MCAODC_01320 0.58 +1.5 252,361 + rluA MCAODC_01320 0.65 +1.3 252,362 - rluA MCAODC_01320 0.65 +0.5 252,362 - rluA MCAODC_01320 0.65 +0.6 252,433 - rluA MCAODC_01320 0.76 +0.8 252,433 - rluA MCAODC_01320 0.76 -0.2 252,473 - rluA MCAODC_01320 0.82 +0.4 252,515 + rluA MCAODC_01320 0.88 +1.5 252,515 + rluA MCAODC_01320 0.88 -0.2 252,515 + rluA MCAODC_01320 0.88 -0.4 252,516 - rluA MCAODC_01320 0.88 -0.3 252,516 - rluA MCAODC_01320 0.88 +2.2 252,551 - +0.3 252,558 + +0.4 252,558 + +0.5 252,558 + -3.9 252,558 + +1.9 252,558 + -0.2 252,559 - -0.8 252,561 + -1.2 252,562 - +0.2 252,571 - -0.3 252,607 + -0.9 252,607 + -0.0 252,607 + -0.3 252,610 - +0.9 252,610 - -0.4 252,621 - -0.5 252,636 + -1.2 252,640 + +1.1 252,640 + +0.1 252,640 + +0.4 252,640 + +1.6 252,640 + +0.4 252,640 + -0.8 252,641 - +2.5 252,641 - -0.1 252,641 - +0.2 252,641 - -1.9 252,641 - +1.0 252,641 - +1.2 252,702 + -1.2 252,779 + +0.1 252,779 + -0.3 252,779 + -0.8 252,780 - -1.1 252,781 + -1.1 252,782 - -1.2 252,804 - -0.6 252,823 - +0.3 252,834 - +0.1 252,838 - -0.0 252,879 + -0.7 252,899 + -0.6 252,911 + -2.5 252,912 - +1.3 252,912 - +0.8 252,912 - -0.3
Or see this region's nucleotide sequence