Experiment: D-Glucose
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt uacR and xdhC are separated by 39 nucleotides xdhC and xdhB overlap by 4 nucleotides xdhB and xdhA are separated by 10 nucleotides
MCAODC_10220: uacR - Putative uric acid sigma-54-dependent transcriptional regulator UacR, at 2,040,680 to 2,042,458
uacR
MCAODC_10225: xdhC - xanthine dehydrogenase iron sulfur-binding subunit XdhC, at 2,042,498 to 2,042,977
xdhC
MCAODC_10230: xdhB - xanthine dehydrogenase FAD-binding subunit XdhB, at 2,042,974 to 2,043,852
xdhB
MCAODC_10235: xdhA - xanthine dehydrogenase molybdenum-binding subunit XdhA, at 2,043,863 to 2,046,160
xdhA
Position (kb)
2042
2043
2044 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2
3 at 2041.974 kb on - strand, within uacR at 2041.974 kb on - strand, within uacR at 2041.974 kb on - strand, within uacR at 2041.974 kb on - strand, within uacR at 2041.981 kb on + strand, within uacR at 2041.981 kb on + strand, within uacR at 2041.981 kb on + strand, within uacR at 2041.982 kb on - strand, within uacR at 2041.982 kb on - strand, within uacR at 2041.982 kb on - strand, within uacR at 2042.030 kb on - strand, within uacR at 2042.037 kb on + strand, within uacR at 2042.038 kb on - strand, within uacR at 2042.048 kb on + strand, within uacR at 2042.048 kb on + strand, within uacR at 2042.049 kb on - strand, within uacR at 2042.065 kb on + strand, within uacR at 2042.119 kb on - strand, within uacR at 2042.206 kb on + strand, within uacR at 2042.207 kb on - strand, within uacR at 2042.207 kb on - strand, within uacR at 2042.242 kb on + strand, within uacR at 2042.268 kb on + strand, within uacR at 2042.269 kb on - strand, within uacR at 2042.269 kb on - strand, within uacR at 2042.269 kb on - strand, within uacR at 2042.269 kb on - strand, within uacR at 2042.279 kb on - strand, within uacR at 2042.368 kb on + strand at 2042.368 kb on + strand at 2042.368 kb on + strand at 2042.413 kb on + strand at 2042.438 kb on + strand at 2042.456 kb on + strand at 2042.457 kb on - strand at 2042.457 kb on - strand at 2042.527 kb on + strand at 2042.527 kb on + strand at 2042.527 kb on + strand at 2042.528 kb on - strand at 2042.531 kb on + strand at 2042.531 kb on + strand at 2042.531 kb on + strand at 2042.531 kb on + strand at 2042.532 kb on - strand at 2042.532 kb on - strand at 2042.532 kb on - strand at 2042.644 kb on + strand, within xdhC at 2042.645 kb on - strand, within xdhC at 2042.660 kb on - strand, within xdhC at 2042.781 kb on + strand, within xdhC at 2042.781 kb on + strand, within xdhC at 2042.781 kb on + strand, within xdhC at 2042.781 kb on + strand, within xdhC at 2042.782 kb on - strand, within xdhC at 2042.782 kb on - strand, within xdhC at 2042.782 kb on - strand, within xdhC at 2042.783 kb on + strand, within xdhC at 2042.783 kb on + strand, within xdhC at 2042.795 kb on + strand, within xdhC at 2042.796 kb on - strand, within xdhC at 2042.796 kb on - strand, within xdhC at 2042.864 kb on + strand, within xdhC at 2042.864 kb on + strand, within xdhC at 2042.864 kb on + strand, within xdhC at 2042.864 kb on + strand, within xdhC at 2042.864 kb on + strand, within xdhC at 2042.865 kb on - strand, within xdhC at 2042.865 kb on - strand, within xdhC at 2042.885 kb on + strand, within xdhC at 2042.956 kb on + strand at 2042.957 kb on - strand at 2042.957 kb on - strand at 2043.114 kb on + strand, within xdhB at 2043.137 kb on - strand, within xdhB at 2043.214 kb on + strand, within xdhB at 2043.296 kb on + strand, within xdhB at 2043.296 kb on + strand, within xdhB at 2043.296 kb on + strand, within xdhB at 2043.297 kb on - strand, within xdhB at 2043.297 kb on - strand, within xdhB at 2043.300 kb on + strand, within xdhB at 2043.301 kb on - strand, within xdhB at 2043.301 kb on - strand, within xdhB at 2043.461 kb on + strand, within xdhB at 2043.461 kb on + strand, within xdhB at 2043.511 kb on - strand, within xdhB at 2043.522 kb on - strand, within xdhB at 2043.522 kb on - strand, within xdhB at 2043.600 kb on + strand, within xdhB at 2043.601 kb on - strand, within xdhB at 2043.601 kb on - strand, within xdhB at 2043.601 kb on - strand, within xdhB at 2043.613 kb on + strand, within xdhB at 2043.613 kb on + strand, within xdhB at 2043.613 kb on + strand, within xdhB at 2043.614 kb on - strand, within xdhB at 2043.621 kb on + strand, within xdhB at 2043.621 kb on + strand, within xdhB at 2043.646 kb on + strand, within xdhB at 2043.647 kb on - strand, within xdhB at 2043.669 kb on + strand, within xdhB at 2043.694 kb on - strand, within xdhB at 2043.700 kb on - strand, within xdhB at 2043.709 kb on - strand, within xdhB at 2043.748 kb on + strand, within xdhB at 2043.833 kb on + strand at 2043.834 kb on - strand at 2043.834 kb on - strand at 2043.894 kb on + strand at 2043.894 kb on + strand at 2043.894 kb on + strand at 2043.894 kb on + strand at 2043.895 kb on - strand at 2043.895 kb on - strand at 2043.895 kb on - strand at 2043.895 kb on - strand at 2043.922 kb on + strand at 2043.922 kb on + strand at 2043.923 kb on - strand at 2043.965 kb on - strand at 2044.006 kb on + strand at 2044.006 kb on + strand at 2044.006 kb on + strand at 2044.006 kb on + strand at 2044.006 kb on + strand at 2044.006 kb on + strand at 2044.007 kb on - strand at 2044.007 kb on - strand at 2044.007 kb on - strand at 2044.007 kb on - strand at 2044.007 kb on - strand at 2044.007 kb on - strand at 2044.007 kb on - strand at 2044.007 kb on - strand at 2044.014 kb on + strand at 2044.089 kb on + strand at 2044.152 kb on - strand, within xdhA at 2044.187 kb on + strand, within xdhA at 2044.188 kb on - strand, within xdhA at 2044.188 kb on - strand, within xdhA at 2044.206 kb on - strand, within xdhA at 2044.301 kb on - strand, within xdhA at 2044.378 kb on - strand, within xdhA at 2044.454 kb on + strand, within xdhA at 2044.454 kb on + strand, within xdhA at 2044.454 kb on + strand, within xdhA at 2044.455 kb on - strand, within xdhA at 2044.455 kb on - strand, within xdhA at 2044.524 kb on - strand, within xdhA at 2044.524 kb on - strand, within xdhA at 2044.524 kb on - strand, within xdhA at 2044.560 kb on + strand, within xdhA at 2044.561 kb on - strand, within xdhA at 2044.561 kb on - strand, within xdhA at 2044.561 kb on - strand, within xdhA at 2044.601 kb on - strand, within xdhA at 2044.766 kb on + strand, within xdhA at 2044.766 kb on + strand, within xdhA at 2044.772 kb on + strand, within xdhA at 2044.792 kb on + strand, within xdhA at 2044.801 kb on - strand, within xdhA at 2044.801 kb on - strand, within xdhA at 2044.801 kb on - strand, within xdhA at 2044.801 kb on - strand, within xdhA
Per-strain Table
Position Strand Gene LocusTag Fraction D-Glucose remove 2,041,974 - uacR MCAODC_10220 0.73 -0.6 2,041,974 - uacR MCAODC_10220 0.73 -1.1 2,041,974 - uacR MCAODC_10220 0.73 +0.6 2,041,974 - uacR MCAODC_10220 0.73 -0.1 2,041,981 + uacR MCAODC_10220 0.73 -0.6 2,041,981 + uacR MCAODC_10220 0.73 +0.0 2,041,981 + uacR MCAODC_10220 0.73 +0.7 2,041,982 - uacR MCAODC_10220 0.73 -1.0 2,041,982 - uacR MCAODC_10220 0.73 +1.2 2,041,982 - uacR MCAODC_10220 0.73 +0.2 2,042,030 - uacR MCAODC_10220 0.76 -2.1 2,042,037 + uacR MCAODC_10220 0.76 -1.0 2,042,038 - uacR MCAODC_10220 0.76 -0.6 2,042,048 + uacR MCAODC_10220 0.77 -4.5 2,042,048 + uacR MCAODC_10220 0.77 +0.3 2,042,049 - uacR MCAODC_10220 0.77 -1.8 2,042,065 + uacR MCAODC_10220 0.78 +0.4 2,042,119 - uacR MCAODC_10220 0.81 -0.7 2,042,206 + uacR MCAODC_10220 0.86 -2.5 2,042,207 - uacR MCAODC_10220 0.86 -0.6 2,042,207 - uacR MCAODC_10220 0.86 -0.7 2,042,242 + uacR MCAODC_10220 0.88 -0.2 2,042,268 + uacR MCAODC_10220 0.89 -2.4 2,042,269 - uacR MCAODC_10220 0.89 -1.4 2,042,269 - uacR MCAODC_10220 0.89 -0.1 2,042,269 - uacR MCAODC_10220 0.89 -0.0 2,042,269 - uacR MCAODC_10220 0.89 -2.3 2,042,279 - uacR MCAODC_10220 0.90 +0.5 2,042,368 + -0.4 2,042,368 + +1.6 2,042,368 + -0.7 2,042,413 + +0.3 2,042,438 + +0.4 2,042,456 + -2.5 2,042,457 - +0.2 2,042,457 - +0.9 2,042,527 + -0.6 2,042,527 + -0.7 2,042,527 + -0.1 2,042,528 - +0.5 2,042,531 + -1.9 2,042,531 + -0.4 2,042,531 + -0.0 2,042,531 + +0.3 2,042,532 - -1.2 2,042,532 - -0.9 2,042,532 - +0.7 2,042,644 + xdhC MCAODC_10225 0.30 -0.0 2,042,645 - xdhC MCAODC_10225 0.31 -0.2 2,042,660 - xdhC MCAODC_10225 0.34 +0.1 2,042,781 + xdhC MCAODC_10225 0.59 -0.3 2,042,781 + xdhC MCAODC_10225 0.59 +0.7 2,042,781 + xdhC MCAODC_10225 0.59 +0.2 2,042,781 + xdhC MCAODC_10225 0.59 -1.7 2,042,782 - xdhC MCAODC_10225 0.59 -1.1 2,042,782 - xdhC MCAODC_10225 0.59 -1.1 2,042,782 - xdhC MCAODC_10225 0.59 +0.3 2,042,783 + xdhC MCAODC_10225 0.59 +0.5 2,042,783 + xdhC MCAODC_10225 0.59 -2.1 2,042,795 + xdhC MCAODC_10225 0.62 +1.6 2,042,796 - xdhC MCAODC_10225 0.62 -0.9 2,042,796 - xdhC MCAODC_10225 0.62 -0.2 2,042,864 + xdhC MCAODC_10225 0.76 +0.3 2,042,864 + xdhC MCAODC_10225 0.76 -0.0 2,042,864 + xdhC MCAODC_10225 0.76 -0.0 2,042,864 + xdhC MCAODC_10225 0.76 +0.4 2,042,864 + xdhC MCAODC_10225 0.76 -2.9 2,042,865 - xdhC MCAODC_10225 0.76 +0.8 2,042,865 - xdhC MCAODC_10225 0.76 +0.7 2,042,885 + xdhC MCAODC_10225 0.81 +1.2 2,042,956 + +0.4 2,042,957 - -0.3 2,042,957 - +1.1 2,043,114 + xdhB MCAODC_10230 0.16 +0.4 2,043,137 - xdhB MCAODC_10230 0.19 +0.4 2,043,214 + xdhB MCAODC_10230 0.27 -3.6 2,043,296 + xdhB MCAODC_10230 0.37 -0.6 2,043,296 + xdhB MCAODC_10230 0.37 -0.7 2,043,296 + xdhB MCAODC_10230 0.37 +0.4 2,043,297 - xdhB MCAODC_10230 0.37 +0.7 2,043,297 - xdhB MCAODC_10230 0.37 -0.7 2,043,300 + xdhB MCAODC_10230 0.37 +0.0 2,043,301 - xdhB MCAODC_10230 0.37 +0.4 2,043,301 - xdhB MCAODC_10230 0.37 +0.6 2,043,461 + xdhB MCAODC_10230 0.55 +2.8 2,043,461 + xdhB MCAODC_10230 0.55 +0.0 2,043,511 - xdhB MCAODC_10230 0.61 +0.5 2,043,522 - xdhB MCAODC_10230 0.62 +0.4 2,043,522 - xdhB MCAODC_10230 0.62 -0.3 2,043,600 + xdhB MCAODC_10230 0.71 +0.6 2,043,601 - xdhB MCAODC_10230 0.71 -0.1 2,043,601 - xdhB MCAODC_10230 0.71 -0.9 2,043,601 - xdhB MCAODC_10230 0.71 +0.2 2,043,613 + xdhB MCAODC_10230 0.73 +1.1 2,043,613 + xdhB MCAODC_10230 0.73 +0.7 2,043,613 + xdhB MCAODC_10230 0.73 -0.2 2,043,614 - xdhB MCAODC_10230 0.73 +0.2 2,043,621 + xdhB MCAODC_10230 0.74 +1.6 2,043,621 + xdhB MCAODC_10230 0.74 +0.9 2,043,646 + xdhB MCAODC_10230 0.76 +0.4 2,043,647 - xdhB MCAODC_10230 0.77 -0.2 2,043,669 + xdhB MCAODC_10230 0.79 -0.2 2,043,694 - xdhB MCAODC_10230 0.82 -1.3 2,043,700 - xdhB MCAODC_10230 0.83 +0.2 2,043,709 - xdhB MCAODC_10230 0.84 +0.6 2,043,748 + xdhB MCAODC_10230 0.88 +1.3 2,043,833 + -1.3 2,043,834 - -0.5 2,043,834 - -1.1 2,043,894 + +0.1 2,043,894 + -0.2 2,043,894 + -0.8 2,043,894 + -2.7 2,043,895 - -1.2 2,043,895 - -0.9 2,043,895 - +0.0 2,043,895 - +0.1 2,043,922 + +0.5 2,043,922 + +1.1 2,043,923 - -0.5 2,043,965 - +0.5 2,044,006 + +0.4 2,044,006 + -0.4 2,044,006 + -1.2 2,044,006 + +0.2 2,044,006 + -2.6 2,044,006 + +2.9 2,044,007 - +0.3 2,044,007 - -1.3 2,044,007 - +0.6 2,044,007 - -0.1 2,044,007 - +0.2 2,044,007 - +0.8 2,044,007 - -1.9 2,044,007 - -0.2 2,044,014 + +1.0 2,044,089 + +0.5 2,044,152 - xdhA MCAODC_10235 0.13 -0.6 2,044,187 + xdhA MCAODC_10235 0.14 -0.8 2,044,188 - xdhA MCAODC_10235 0.14 -0.7 2,044,188 - xdhA MCAODC_10235 0.14 -0.4 2,044,206 - xdhA MCAODC_10235 0.15 -0.1 2,044,301 - xdhA MCAODC_10235 0.19 +1.8 2,044,378 - xdhA MCAODC_10235 0.22 -1.0 2,044,454 + xdhA MCAODC_10235 0.26 +0.4 2,044,454 + xdhA MCAODC_10235 0.26 +0.8 2,044,454 + xdhA MCAODC_10235 0.26 -1.5 2,044,455 - xdhA MCAODC_10235 0.26 -0.3 2,044,455 - xdhA MCAODC_10235 0.26 +1.0 2,044,524 - xdhA MCAODC_10235 0.29 -0.6 2,044,524 - xdhA MCAODC_10235 0.29 -0.0 2,044,524 - xdhA MCAODC_10235 0.29 +0.8 2,044,560 + xdhA MCAODC_10235 0.30 +0.7 2,044,561 - xdhA MCAODC_10235 0.30 -0.5 2,044,561 - xdhA MCAODC_10235 0.30 -3.9 2,044,561 - xdhA MCAODC_10235 0.30 +0.4 2,044,601 - xdhA MCAODC_10235 0.32 -0.5 2,044,766 + xdhA MCAODC_10235 0.39 +0.4 2,044,766 + xdhA MCAODC_10235 0.39 -0.3 2,044,772 + xdhA MCAODC_10235 0.40 +0.4 2,044,792 + xdhA MCAODC_10235 0.40 -0.3 2,044,801 - xdhA MCAODC_10235 0.41 -0.6 2,044,801 - xdhA MCAODC_10235 0.41 +0.3 2,044,801 - xdhA MCAODC_10235 0.41 +0.5 2,044,801 - xdhA MCAODC_10235 0.41 +1.1
Or see this region's nucleotide sequence