Experiment: a-Ketoglutaric (C)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_2594 and PfGW456L13_2595 are separated by 146 nucleotides PfGW456L13_2595 and PfGW456L13_2596 are separated by 205 nucleotides
PfGW456L13_2594 - Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4), at 2,882,370 to 2,883,269
_2594
PfGW456L13_2595 - Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family, at 2,883,416 to 2,883,817
_2595
PfGW456L13_2596 - Transcriptional regulator, LysR family, at 2,884,023 to 2,884,952
_2596
Position (kb)
2883
2884 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2
3 at 2882.500 kb on + strand, within PfGW456L13_2594 at 2882.500 kb on + strand, within PfGW456L13_2594 at 2882.611 kb on + strand, within PfGW456L13_2594 at 2882.612 kb on - strand, within PfGW456L13_2594 at 2882.612 kb on - strand, within PfGW456L13_2594 at 2882.615 kb on + strand, within PfGW456L13_2594 at 2882.615 kb on + strand, within PfGW456L13_2594 at 2882.616 kb on - strand, within PfGW456L13_2594 at 2882.635 kb on + strand, within PfGW456L13_2594 at 2882.635 kb on + strand, within PfGW456L13_2594 at 2882.635 kb on + strand, within PfGW456L13_2594 at 2882.636 kb on - strand, within PfGW456L13_2594 at 2882.636 kb on - strand, within PfGW456L13_2594 at 2882.756 kb on - strand, within PfGW456L13_2594 at 2882.770 kb on + strand, within PfGW456L13_2594 at 2882.771 kb on - strand, within PfGW456L13_2594 at 2882.822 kb on - strand, within PfGW456L13_2594 at 2882.849 kb on - strand, within PfGW456L13_2594 at 2882.971 kb on - strand, within PfGW456L13_2594 at 2883.040 kb on + strand, within PfGW456L13_2594 at 2883.139 kb on + strand, within PfGW456L13_2594 at 2883.140 kb on - strand, within PfGW456L13_2594 at 2883.140 kb on - strand, within PfGW456L13_2594 at 2883.183 kb on - strand at 2883.250 kb on - strand at 2883.250 kb on - strand at 2883.250 kb on - strand at 2883.306 kb on + strand at 2883.306 kb on + strand at 2883.307 kb on - strand at 2883.307 kb on - strand at 2883.400 kb on + strand at 2883.400 kb on + strand at 2883.400 kb on + strand at 2883.401 kb on - strand at 2883.401 kb on - strand at 2883.401 kb on - strand at 2883.417 kb on + strand at 2883.418 kb on - strand at 2883.600 kb on + strand, within PfGW456L13_2595 at 2883.601 kb on - strand, within PfGW456L13_2595 at 2883.694 kb on - strand, within PfGW456L13_2595 at 2883.694 kb on - strand, within PfGW456L13_2595 at 2883.744 kb on + strand, within PfGW456L13_2595 at 2883.745 kb on - strand, within PfGW456L13_2595 at 2883.801 kb on + strand at 2883.801 kb on + strand at 2883.802 kb on - strand at 2883.802 kb on - strand at 2883.802 kb on - strand at 2883.845 kb on + strand at 2883.850 kb on + strand at 2883.851 kb on - strand at 2883.851 kb on - strand at 2883.954 kb on + strand at 2883.954 kb on + strand at 2883.954 kb on + strand at 2883.954 kb on + strand at 2883.954 kb on + strand at 2883.954 kb on + strand at 2883.954 kb on + strand at 2883.954 kb on + strand at 2883.954 kb on + strand at 2883.954 kb on + strand at 2883.954 kb on + strand at 2883.954 kb on + strand at 2883.954 kb on + strand at 2883.954 kb on + strand at 2883.955 kb on - strand at 2883.955 kb on - strand at 2883.955 kb on - strand at 2883.955 kb on - strand at 2883.955 kb on - strand at 2883.955 kb on - strand at 2883.955 kb on - strand at 2883.955 kb on - strand at 2883.955 kb on - strand at 2883.974 kb on + strand at 2883.974 kb on + strand at 2883.974 kb on + strand at 2883.974 kb on + strand at 2883.974 kb on + strand at 2883.974 kb on + strand at 2883.975 kb on - strand at 2883.975 kb on - strand at 2883.975 kb on - strand at 2883.975 kb on - strand at 2883.975 kb on - strand at 2883.975 kb on - strand at 2883.975 kb on - strand at 2884.132 kb on + strand, within PfGW456L13_2596 at 2884.133 kb on - strand, within PfGW456L13_2596 at 2884.133 kb on - strand, within PfGW456L13_2596 at 2884.155 kb on + strand, within PfGW456L13_2596 at 2884.155 kb on + strand, within PfGW456L13_2596 at 2884.156 kb on - strand, within PfGW456L13_2596 at 2884.156 kb on - strand, within PfGW456L13_2596 at 2884.156 kb on - strand, within PfGW456L13_2596 at 2884.174 kb on + strand, within PfGW456L13_2596 at 2884.175 kb on - strand, within PfGW456L13_2596 at 2884.175 kb on - strand, within PfGW456L13_2596 at 2884.175 kb on - strand, within PfGW456L13_2596 at 2884.175 kb on - strand, within PfGW456L13_2596 at 2884.264 kb on + strand, within PfGW456L13_2596 at 2884.264 kb on + strand at 2884.265 kb on - strand, within PfGW456L13_2596 at 2884.328 kb on - strand, within PfGW456L13_2596 at 2884.355 kb on + strand, within PfGW456L13_2596 at 2884.355 kb on + strand, within PfGW456L13_2596 at 2884.355 kb on + strand, within PfGW456L13_2596 at 2884.356 kb on - strand, within PfGW456L13_2596 at 2884.356 kb on - strand, within PfGW456L13_2596 at 2884.379 kb on - strand, within PfGW456L13_2596 at 2884.379 kb on - strand, within PfGW456L13_2596 at 2884.442 kb on - strand, within PfGW456L13_2596 at 2884.658 kb on - strand, within PfGW456L13_2596 at 2884.658 kb on - strand, within PfGW456L13_2596
Per-strain Table
Position Strand Gene LocusTag Fraction a-Ketoglutaric (C) remove 2,882,500 + PfGW456L13_2594 0.14 +0.6 2,882,500 + PfGW456L13_2594 0.14 -3.4 2,882,611 + PfGW456L13_2594 0.27 -3.5 2,882,612 - PfGW456L13_2594 0.27 +1.6 2,882,612 - PfGW456L13_2594 0.27 -0.7 2,882,615 + PfGW456L13_2594 0.27 +0.2 2,882,615 + PfGW456L13_2594 0.27 +1.4 2,882,616 - PfGW456L13_2594 0.27 +1.3 2,882,635 + PfGW456L13_2594 0.29 +1.1 2,882,635 + PfGW456L13_2594 0.29 -0.3 2,882,635 + PfGW456L13_2594 0.29 -3.0 2,882,636 - PfGW456L13_2594 0.30 -0.0 2,882,636 - PfGW456L13_2594 0.30 -1.4 2,882,756 - PfGW456L13_2594 0.43 -0.9 2,882,770 + PfGW456L13_2594 0.44 +2.7 2,882,771 - PfGW456L13_2594 0.45 -1.0 2,882,822 - PfGW456L13_2594 0.50 -1.2 2,882,849 - PfGW456L13_2594 0.53 +0.8 2,882,971 - PfGW456L13_2594 0.67 +0.7 2,883,040 + PfGW456L13_2594 0.74 -1.2 2,883,139 + PfGW456L13_2594 0.85 +1.9 2,883,140 - PfGW456L13_2594 0.86 +0.7 2,883,140 - PfGW456L13_2594 0.86 -1.5 2,883,183 - +0.8 2,883,250 - +3.3 2,883,250 - -1.9 2,883,250 - -3.0 2,883,306 + -0.4 2,883,306 + -1.5 2,883,307 - -1.5 2,883,307 - +2.3 2,883,400 + -1.0 2,883,400 + +1.0 2,883,400 + +3.2 2,883,401 - -3.2 2,883,401 - +2.0 2,883,401 - +0.0 2,883,417 + +0.4 2,883,418 - +0.3 2,883,600 + PfGW456L13_2595 0.46 -3.7 2,883,601 - PfGW456L13_2595 0.46 -2.7 2,883,694 - PfGW456L13_2595 0.69 -0.6 2,883,694 - PfGW456L13_2595 0.69 -2.5 2,883,744 + PfGW456L13_2595 0.82 -2.8 2,883,745 - PfGW456L13_2595 0.82 -2.6 2,883,801 + +1.2 2,883,801 + -1.0 2,883,802 - -1.9 2,883,802 - +1.2 2,883,802 - +0.2 2,883,845 + -1.7 2,883,850 + -2.0 2,883,851 - +2.1 2,883,851 - +1.4 2,883,954 + -2.2 2,883,954 + -3.0 2,883,954 + -4.1 2,883,954 + -2.8 2,883,954 + -1.1 2,883,954 + +2.4 2,883,954 + +2.3 2,883,954 + +0.3 2,883,954 + +0.3 2,883,954 + -1.7 2,883,954 + -1.3 2,883,954 + +0.9 2,883,954 + -0.6 2,883,954 + -2.8 2,883,955 - -0.1 2,883,955 - +1.6 2,883,955 - -2.5 2,883,955 - +2.1 2,883,955 - -0.7 2,883,955 - -1.7 2,883,955 - +1.4 2,883,955 - -1.0 2,883,955 - -2.0 2,883,974 + +1.1 2,883,974 + -1.5 2,883,974 + +1.7 2,883,974 + +0.1 2,883,974 + +2.6 2,883,974 + -1.8 2,883,975 - +2.4 2,883,975 - +1.0 2,883,975 - +1.6 2,883,975 - +2.9 2,883,975 - -1.3 2,883,975 - +1.1 2,883,975 - +0.2 2,884,132 + PfGW456L13_2596 0.12 -0.9 2,884,133 - PfGW456L13_2596 0.12 -0.6 2,884,133 - PfGW456L13_2596 0.12 -1.0 2,884,155 + PfGW456L13_2596 0.14 +2.6 2,884,155 + PfGW456L13_2596 0.14 -1.9 2,884,156 - PfGW456L13_2596 0.14 +1.6 2,884,156 - PfGW456L13_2596 0.14 -3.5 2,884,156 - PfGW456L13_2596 0.14 +2.3 2,884,174 + PfGW456L13_2596 0.16 -1.5 2,884,175 - PfGW456L13_2596 0.16 +0.8 2,884,175 - PfGW456L13_2596 0.16 -2.6 2,884,175 - PfGW456L13_2596 0.16 +1.6 2,884,175 - PfGW456L13_2596 0.16 -1.2 2,884,264 + PfGW456L13_2596 0.26 -0.2 2,884,264 + +0.3 2,884,265 - PfGW456L13_2596 0.26 -0.9 2,884,328 - PfGW456L13_2596 0.33 +0.5 2,884,355 + PfGW456L13_2596 0.36 +0.8 2,884,355 + PfGW456L13_2596 0.36 +2.7 2,884,355 + PfGW456L13_2596 0.36 -1.0 2,884,356 - PfGW456L13_2596 0.36 +0.3 2,884,356 - PfGW456L13_2596 0.36 +0.8 2,884,379 - PfGW456L13_2596 0.38 -0.0 2,884,379 - PfGW456L13_2596 0.38 +1.4 2,884,442 - PfGW456L13_2596 0.45 -2.5 2,884,658 - PfGW456L13_2596 0.68 +1.2 2,884,658 - PfGW456L13_2596 0.68 +3.6
Or see this region's nucleotide sequence