Experiment: a-Ketoglutaric (C)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_2319 and PfGW456L13_2320 are separated by 93 nucleotides PfGW456L13_2320 and PfGW456L13_2321 are separated by 14 nucleotides PfGW456L13_2321 and PfGW456L13_2322 are separated by 169 nucleotides
PfGW456L13_2319 - Short-chain dehydrogenase, associated with 2-hydroxychromene-2-carboxylate isomerase family protein, at 2,544,228 to 2,544,956
_2319
PfGW456L13_2320 - Transcriptional regulator, TetR family, in cluster with 2-hydroxychromene-2-carboxylate isomerase family protein, glutathione-dependent, at 2,545,050 to 2,545,610
_2320
PfGW456L13_2321 - Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1), at 2,545,625 to 2,545,906
_2321
PfGW456L13_2322 - Threonine and homoserine efflux system, at 2,546,076 to 2,546,900
_2322
Position (kb)
2545
2546 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2
3
4
5
6 at 2544.643 kb on + strand, within PfGW456L13_2319 at 2544.644 kb on - strand, within PfGW456L13_2319 at 2544.644 kb on - strand, within PfGW456L13_2319 at 2544.732 kb on + strand, within PfGW456L13_2319 at 2544.732 kb on + strand, within PfGW456L13_2319 at 2544.732 kb on + strand, within PfGW456L13_2319 at 2544.732 kb on + strand, within PfGW456L13_2319 at 2544.733 kb on - strand, within PfGW456L13_2319 at 2544.733 kb on - strand, within PfGW456L13_2319 at 2544.733 kb on - strand, within PfGW456L13_2319 at 2544.733 kb on - strand, within PfGW456L13_2319 at 2544.753 kb on + strand, within PfGW456L13_2319 at 2544.753 kb on + strand, within PfGW456L13_2319 at 2544.754 kb on - strand, within PfGW456L13_2319 at 2544.754 kb on - strand, within PfGW456L13_2319 at 2544.754 kb on - strand, within PfGW456L13_2319 at 2544.814 kb on - strand, within PfGW456L13_2319 at 2544.933 kb on - strand at 2544.933 kb on - strand at 2544.950 kb on + strand at 2544.951 kb on - strand at 2544.960 kb on + strand at 2544.961 kb on - strand at 2545.056 kb on + strand at 2545.057 kb on - strand at 2545.191 kb on + strand, within PfGW456L13_2320 at 2545.191 kb on + strand, within PfGW456L13_2320 at 2545.191 kb on + strand, within PfGW456L13_2320 at 2545.191 kb on + strand, within PfGW456L13_2320 at 2545.191 kb on + strand, within PfGW456L13_2320 at 2545.191 kb on + strand, within PfGW456L13_2320 at 2545.191 kb on + strand, within PfGW456L13_2320 at 2545.192 kb on - strand, within PfGW456L13_2320 at 2545.192 kb on - strand, within PfGW456L13_2320 at 2545.192 kb on - strand, within PfGW456L13_2320 at 2545.192 kb on - strand, within PfGW456L13_2320 at 2545.192 kb on - strand, within PfGW456L13_2320 at 2545.192 kb on - strand, within PfGW456L13_2320 at 2545.192 kb on - strand, within PfGW456L13_2320 at 2545.314 kb on + strand, within PfGW456L13_2320 at 2545.322 kb on + strand, within PfGW456L13_2320 at 2545.322 kb on + strand, within PfGW456L13_2320 at 2545.322 kb on + strand, within PfGW456L13_2320 at 2545.322 kb on + strand, within PfGW456L13_2320 at 2545.322 kb on + strand, within PfGW456L13_2320 at 2545.323 kb on - strand, within PfGW456L13_2320 at 2545.323 kb on - strand, within PfGW456L13_2320 at 2545.499 kb on + strand, within PfGW456L13_2320 at 2545.499 kb on + strand, within PfGW456L13_2320 at 2545.499 kb on + strand, within PfGW456L13_2320 at 2545.500 kb on - strand, within PfGW456L13_2320 at 2545.569 kb on + strand at 2545.569 kb on + strand at 2545.570 kb on - strand at 2545.626 kb on + strand at 2545.626 kb on + strand at 2545.626 kb on + strand at 2545.627 kb on - strand at 2545.657 kb on + strand at 2545.658 kb on - strand, within PfGW456L13_2321 at 2545.734 kb on + strand, within PfGW456L13_2321 at 2545.734 kb on + strand, within PfGW456L13_2321 at 2545.735 kb on - strand, within PfGW456L13_2321 at 2545.735 kb on - strand, within PfGW456L13_2321 at 2545.735 kb on - strand, within PfGW456L13_2321 at 2545.735 kb on - strand, within PfGW456L13_2321 at 2545.878 kb on - strand at 2545.907 kb on + strand at 2545.908 kb on - strand at 2545.916 kb on + strand at 2545.916 kb on + strand at 2545.916 kb on + strand at 2545.916 kb on + strand at 2545.916 kb on + strand at 2545.916 kb on + strand at 2545.917 kb on - strand at 2545.917 kb on - strand at 2545.918 kb on + strand at 2545.918 kb on + strand at 2545.919 kb on - strand at 2545.919 kb on - strand at 2545.919 kb on - strand at 2545.919 kb on - strand at 2545.919 kb on - strand at 2545.919 kb on - strand at 2545.919 kb on - strand at 2545.986 kb on - strand at 2546.036 kb on + strand at 2546.036 kb on + strand at 2546.036 kb on + strand at 2546.037 kb on - strand at 2546.037 kb on - strand at 2546.037 kb on - strand at 2546.037 kb on - strand at 2546.051 kb on + strand at 2546.052 kb on - strand at 2546.052 kb on - strand at 2546.052 kb on - strand at 2546.067 kb on + strand at 2546.067 kb on + strand at 2546.067 kb on + strand at 2546.068 kb on - strand at 2546.068 kb on - strand at 2546.068 kb on - strand at 2546.068 kb on - strand at 2546.106 kb on - strand at 2546.106 kb on - strand at 2546.106 kb on - strand at 2546.182 kb on + strand, within PfGW456L13_2322 at 2546.182 kb on + strand, within PfGW456L13_2322 at 2546.182 kb on + strand, within PfGW456L13_2322 at 2546.182 kb on + strand, within PfGW456L13_2322 at 2546.182 kb on + strand, within PfGW456L13_2322 at 2546.183 kb on - strand, within PfGW456L13_2322 at 2546.183 kb on - strand, within PfGW456L13_2322 at 2546.231 kb on + strand, within PfGW456L13_2322 at 2546.293 kb on + strand, within PfGW456L13_2322 at 2546.293 kb on + strand, within PfGW456L13_2322 at 2546.293 kb on + strand, within PfGW456L13_2322 at 2546.293 kb on + strand, within PfGW456L13_2322 at 2546.331 kb on + strand, within PfGW456L13_2322 at 2546.331 kb on + strand, within PfGW456L13_2322 at 2546.334 kb on - strand, within PfGW456L13_2322 at 2546.334 kb on - strand, within PfGW456L13_2322 at 2546.378 kb on + strand, within PfGW456L13_2322 at 2546.412 kb on + strand, within PfGW456L13_2322 at 2546.413 kb on - strand, within PfGW456L13_2322 at 2546.474 kb on - strand, within PfGW456L13_2322 at 2546.474 kb on - strand, within PfGW456L13_2322 at 2546.474 kb on - strand, within PfGW456L13_2322 at 2546.517 kb on + strand, within PfGW456L13_2322 at 2546.517 kb on + strand, within PfGW456L13_2322 at 2546.565 kb on + strand, within PfGW456L13_2322 at 2546.566 kb on - strand, within PfGW456L13_2322 at 2546.566 kb on - strand, within PfGW456L13_2322 at 2546.566 kb on - strand, within PfGW456L13_2322 at 2546.566 kb on - strand, within PfGW456L13_2322 at 2546.566 kb on - strand, within PfGW456L13_2322 at 2546.566 kb on - strand, within PfGW456L13_2322 at 2546.566 kb on - strand, within PfGW456L13_2322 at 2546.620 kb on + strand, within PfGW456L13_2322 at 2546.620 kb on + strand, within PfGW456L13_2322 at 2546.620 kb on + strand, within PfGW456L13_2322 at 2546.620 kb on + strand, within PfGW456L13_2322 at 2546.621 kb on - strand, within PfGW456L13_2322 at 2546.621 kb on - strand, within PfGW456L13_2322 at 2546.621 kb on - strand, within PfGW456L13_2322 at 2546.621 kb on - strand, within PfGW456L13_2322 at 2546.621 kb on - strand, within PfGW456L13_2322 at 2546.693 kb on + strand, within PfGW456L13_2322 at 2546.693 kb on + strand, within PfGW456L13_2322 at 2546.693 kb on + strand, within PfGW456L13_2322 at 2546.693 kb on + strand, within PfGW456L13_2322 at 2546.693 kb on + strand, within PfGW456L13_2322 at 2546.693 kb on + strand, within PfGW456L13_2322 at 2546.693 kb on + strand, within PfGW456L13_2322 at 2546.694 kb on - strand, within PfGW456L13_2322 at 2546.694 kb on - strand, within PfGW456L13_2322 at 2546.694 kb on - strand, within PfGW456L13_2322 at 2546.694 kb on - strand, within PfGW456L13_2322 at 2546.694 kb on - strand, within PfGW456L13_2322 at 2546.694 kb on - strand, within PfGW456L13_2322 at 2546.694 kb on - strand, within PfGW456L13_2322 at 2546.694 kb on - strand, within PfGW456L13_2322 at 2546.695 kb on + strand, within PfGW456L13_2322 at 2546.695 kb on + strand, within PfGW456L13_2322 at 2546.695 kb on + strand, within PfGW456L13_2322 at 2546.695 kb on + strand, within PfGW456L13_2322 at 2546.695 kb on + strand, within PfGW456L13_2322 at 2546.695 kb on + strand, within PfGW456L13_2322 at 2546.695 kb on + strand, within PfGW456L13_2322 at 2546.695 kb on + strand, within PfGW456L13_2322 at 2546.695 kb on + strand, within PfGW456L13_2322 at 2546.695 kb on + strand, within PfGW456L13_2322 at 2546.695 kb on + strand, within PfGW456L13_2322 at 2546.695 kb on + strand, within PfGW456L13_2322 at 2546.696 kb on - strand, within PfGW456L13_2322 at 2546.696 kb on - strand, within PfGW456L13_2322 at 2546.696 kb on - strand, within PfGW456L13_2322 at 2546.696 kb on - strand, within PfGW456L13_2322 at 2546.696 kb on - strand, within PfGW456L13_2322 at 2546.696 kb on - strand, within PfGW456L13_2322 at 2546.696 kb on - strand, within PfGW456L13_2322 at 2546.696 kb on - strand, within PfGW456L13_2322 at 2546.696 kb on - strand, within PfGW456L13_2322 at 2546.696 kb on - strand, within PfGW456L13_2322 at 2546.696 kb on - strand, within PfGW456L13_2322 at 2546.732 kb on - strand, within PfGW456L13_2322 at 2546.787 kb on + strand, within PfGW456L13_2322 at 2546.788 kb on - strand, within PfGW456L13_2322 at 2546.788 kb on - strand, within PfGW456L13_2322 at 2546.788 kb on - strand, within PfGW456L13_2322 at 2546.823 kb on + strand at 2546.823 kb on + strand at 2546.823 kb on + strand at 2546.823 kb on + strand at 2546.823 kb on + strand at 2546.823 kb on + strand at 2546.824 kb on - strand at 2546.824 kb on - strand at 2546.904 kb on + strand at 2546.904 kb on + strand at 2546.904 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction a-Ketoglutaric (C) remove 2,544,643 + PfGW456L13_2319 0.57 -0.9 2,544,644 - PfGW456L13_2319 0.57 -0.8 2,544,644 - PfGW456L13_2319 0.57 -1.5 2,544,732 + PfGW456L13_2319 0.69 -1.2 2,544,732 + PfGW456L13_2319 0.69 -3.1 2,544,732 + PfGW456L13_2319 0.69 +0.3 2,544,732 + PfGW456L13_2319 0.69 -2.2 2,544,733 - PfGW456L13_2319 0.69 +2.4 2,544,733 - PfGW456L13_2319 0.69 -1.5 2,544,733 - PfGW456L13_2319 0.69 -0.0 2,544,733 - PfGW456L13_2319 0.69 -2.4 2,544,753 + PfGW456L13_2319 0.72 -0.6 2,544,753 + PfGW456L13_2319 0.72 +5.8 2,544,754 - PfGW456L13_2319 0.72 -1.0 2,544,754 - PfGW456L13_2319 0.72 -0.2 2,544,754 - PfGW456L13_2319 0.72 +2.1 2,544,814 - PfGW456L13_2319 0.80 -2.5 2,544,933 - +0.4 2,544,933 - -2.6 2,544,950 + -3.5 2,544,951 - +0.9 2,544,960 + +1.1 2,544,961 - +0.3 2,545,056 + +1.9 2,545,057 - -1.6 2,545,191 + PfGW456L13_2320 0.25 +1.8 2,545,191 + PfGW456L13_2320 0.25 -2.2 2,545,191 + PfGW456L13_2320 0.25 -2.3 2,545,191 + PfGW456L13_2320 0.25 -1.6 2,545,191 + PfGW456L13_2320 0.25 -1.3 2,545,191 + PfGW456L13_2320 0.25 +1.4 2,545,191 + PfGW456L13_2320 0.25 +0.7 2,545,192 - PfGW456L13_2320 0.25 -0.9 2,545,192 - PfGW456L13_2320 0.25 +0.9 2,545,192 - PfGW456L13_2320 0.25 +0.3 2,545,192 - PfGW456L13_2320 0.25 -0.9 2,545,192 - PfGW456L13_2320 0.25 +1.2 2,545,192 - PfGW456L13_2320 0.25 +1.2 2,545,192 - PfGW456L13_2320 0.25 +1.2 2,545,314 + PfGW456L13_2320 0.47 +1.4 2,545,322 + PfGW456L13_2320 0.48 +1.2 2,545,322 + PfGW456L13_2320 0.48 +0.9 2,545,322 + PfGW456L13_2320 0.48 -0.4 2,545,322 + PfGW456L13_2320 0.48 +0.2 2,545,322 + PfGW456L13_2320 0.48 +0.6 2,545,323 - PfGW456L13_2320 0.49 -1.9 2,545,323 - PfGW456L13_2320 0.49 +1.4 2,545,499 + PfGW456L13_2320 0.80 -1.9 2,545,499 + PfGW456L13_2320 0.80 +2.3 2,545,499 + PfGW456L13_2320 0.80 -1.8 2,545,500 - PfGW456L13_2320 0.80 -2.0 2,545,569 + +2.1 2,545,569 + +2.3 2,545,570 - -2.4 2,545,626 + +0.7 2,545,626 + -3.0 2,545,626 + +1.6 2,545,627 - -0.5 2,545,657 + -0.2 2,545,658 - PfGW456L13_2321 0.12 -2.2 2,545,734 + PfGW456L13_2321 0.39 -1.6 2,545,734 + PfGW456L13_2321 0.39 +1.0 2,545,735 - PfGW456L13_2321 0.39 -0.4 2,545,735 - PfGW456L13_2321 0.39 -2.3 2,545,735 - PfGW456L13_2321 0.39 -0.8 2,545,735 - PfGW456L13_2321 0.39 -3.6 2,545,878 - +1.2 2,545,907 + +1.0 2,545,908 - +1.5 2,545,916 + -2.3 2,545,916 + +1.0 2,545,916 + +0.8 2,545,916 + -0.8 2,545,916 + +0.6 2,545,916 + +0.0 2,545,917 - +0.8 2,545,917 - -1.0 2,545,918 + +1.0 2,545,918 + +0.4 2,545,919 - -0.7 2,545,919 - +1.4 2,545,919 - +1.3 2,545,919 - -1.6 2,545,919 - +0.5 2,545,919 - +1.9 2,545,919 - +0.8 2,545,986 - +0.6 2,546,036 + +0.4 2,546,036 + +0.6 2,546,036 + -0.2 2,546,037 - -0.2 2,546,037 - -2.0 2,546,037 - +0.4 2,546,037 - +1.7 2,546,051 + -2.0 2,546,052 - -1.1 2,546,052 - +0.8 2,546,052 - -3.1 2,546,067 + -1.6 2,546,067 + +0.8 2,546,067 + -0.5 2,546,068 - -1.1 2,546,068 - +1.1 2,546,068 - +2.1 2,546,068 - +0.5 2,546,106 - -0.6 2,546,106 - +1.8 2,546,106 - -1.2 2,546,182 + PfGW456L13_2322 0.13 +0.1 2,546,182 + PfGW456L13_2322 0.13 +1.8 2,546,182 + PfGW456L13_2322 0.13 -1.4 2,546,182 + PfGW456L13_2322 0.13 -0.8 2,546,182 + PfGW456L13_2322 0.13 +0.5 2,546,183 - PfGW456L13_2322 0.13 +1.6 2,546,183 - PfGW456L13_2322 0.13 -2.9 2,546,231 + PfGW456L13_2322 0.19 +0.2 2,546,293 + PfGW456L13_2322 0.26 +1.0 2,546,293 + PfGW456L13_2322 0.26 +1.3 2,546,293 + PfGW456L13_2322 0.26 +1.0 2,546,293 + PfGW456L13_2322 0.26 -1.5 2,546,331 + PfGW456L13_2322 0.31 -1.8 2,546,331 + PfGW456L13_2322 0.31 +1.0 2,546,334 - PfGW456L13_2322 0.31 +0.7 2,546,334 - PfGW456L13_2322 0.31 +0.8 2,546,378 + PfGW456L13_2322 0.37 -3.1 2,546,412 + PfGW456L13_2322 0.41 +0.4 2,546,413 - PfGW456L13_2322 0.41 -0.9 2,546,474 - PfGW456L13_2322 0.48 +1.4 2,546,474 - PfGW456L13_2322 0.48 -0.8 2,546,474 - PfGW456L13_2322 0.48 -1.1 2,546,517 + PfGW456L13_2322 0.53 +1.5 2,546,517 + PfGW456L13_2322 0.53 +3.3 2,546,565 + PfGW456L13_2322 0.59 +3.0 2,546,566 - PfGW456L13_2322 0.59 +0.7 2,546,566 - PfGW456L13_2322 0.59 -1.9 2,546,566 - PfGW456L13_2322 0.59 -0.8 2,546,566 - PfGW456L13_2322 0.59 -0.5 2,546,566 - PfGW456L13_2322 0.59 +0.3 2,546,566 - PfGW456L13_2322 0.59 +0.9 2,546,566 - PfGW456L13_2322 0.59 +1.0 2,546,620 + PfGW456L13_2322 0.66 -2.0 2,546,620 + PfGW456L13_2322 0.66 +0.5 2,546,620 + PfGW456L13_2322 0.66 +0.6 2,546,620 + PfGW456L13_2322 0.66 +0.9 2,546,621 - PfGW456L13_2322 0.66 -1.7 2,546,621 - PfGW456L13_2322 0.66 +0.7 2,546,621 - PfGW456L13_2322 0.66 +0.5 2,546,621 - PfGW456L13_2322 0.66 +2.9 2,546,621 - PfGW456L13_2322 0.66 +1.8 2,546,693 + PfGW456L13_2322 0.75 +0.8 2,546,693 + PfGW456L13_2322 0.75 -0.9 2,546,693 + PfGW456L13_2322 0.75 -0.4 2,546,693 + PfGW456L13_2322 0.75 -2.1 2,546,693 + PfGW456L13_2322 0.75 +1.7 2,546,693 + PfGW456L13_2322 0.75 -0.8 2,546,693 + PfGW456L13_2322 0.75 -1.8 2,546,694 - PfGW456L13_2322 0.75 +0.8 2,546,694 - PfGW456L13_2322 0.75 -0.2 2,546,694 - PfGW456L13_2322 0.75 -0.9 2,546,694 - PfGW456L13_2322 0.75 -1.9 2,546,694 - PfGW456L13_2322 0.75 -1.6 2,546,694 - PfGW456L13_2322 0.75 +2.6 2,546,694 - PfGW456L13_2322 0.75 -2.8 2,546,694 - PfGW456L13_2322 0.75 +2.1 2,546,695 + PfGW456L13_2322 0.75 +1.2 2,546,695 + PfGW456L13_2322 0.75 +2.5 2,546,695 + PfGW456L13_2322 0.75 +0.0 2,546,695 + PfGW456L13_2322 0.75 +3.1 2,546,695 + PfGW456L13_2322 0.75 -2.2 2,546,695 + PfGW456L13_2322 0.75 -3.7 2,546,695 + PfGW456L13_2322 0.75 -1.6 2,546,695 + PfGW456L13_2322 0.75 -1.6 2,546,695 + PfGW456L13_2322 0.75 +0.3 2,546,695 + PfGW456L13_2322 0.75 +0.8 2,546,695 + PfGW456L13_2322 0.75 +2.3 2,546,695 + PfGW456L13_2322 0.75 +1.5 2,546,696 - PfGW456L13_2322 0.75 +0.6 2,546,696 - PfGW456L13_2322 0.75 +0.8 2,546,696 - PfGW456L13_2322 0.75 +0.2 2,546,696 - PfGW456L13_2322 0.75 +1.0 2,546,696 - PfGW456L13_2322 0.75 -0.9 2,546,696 - PfGW456L13_2322 0.75 -0.5 2,546,696 - PfGW456L13_2322 0.75 +2.2 2,546,696 - PfGW456L13_2322 0.75 +1.6 2,546,696 - PfGW456L13_2322 0.75 +1.1 2,546,696 - PfGW456L13_2322 0.75 +1.0 2,546,696 - PfGW456L13_2322 0.75 +2.5 2,546,732 - PfGW456L13_2322 0.80 +2.1 2,546,787 + PfGW456L13_2322 0.86 -2.7 2,546,788 - PfGW456L13_2322 0.86 +1.4 2,546,788 - PfGW456L13_2322 0.86 -0.0 2,546,788 - PfGW456L13_2322 0.86 +1.0 2,546,823 + +1.4 2,546,823 + +0.9 2,546,823 + +1.2 2,546,823 + +0.6 2,546,823 + -0.4 2,546,823 + -0.9 2,546,824 - -3.0 2,546,824 - +1.3 2,546,904 + +0.8 2,546,904 + +3.1 2,546,904 + -2.0
Or see this region's nucleotide sequence