Experiment: a-Ketoglutaric (C)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt PfGW456L13_1221 and PfGW456L13_1222 overlap by 4 nucleotides PfGW456L13_1222 and PfGW456L13_1223 are separated by 143 nucleotides PfGW456L13_1223 and PfGW456L13_1224 are separated by 10 nucleotides
PfGW456L13_1221 - Anthranilate phosphoribosyltransferase (EC 2.4.2.18), at 1,363,919 to 1,364,968
_1221
PfGW456L13_1222 - Indole-3-glycerol phosphate synthase (EC 4.1.1.48), at 1,364,965 to 1,365,801
_1222
PfGW456L13_1223 - Lipoate-protein ligase A, at 1,365,945 to 1,366,646
_1223
PfGW456L13_1224 - Vfr transcriptional regulator / Cyclic AMP receptor protein, at 1,366,657 to 1,367,301
_1224
Position (kb)
1364
1365
1366 Strain fitness (log2 ratio)
-5
-4
-3
-2
-1
0
1
2
3
4 at 1364.185 kb on + strand, within PfGW456L13_1221 at 1364.185 kb on + strand, within PfGW456L13_1221 at 1364.186 kb on - strand, within PfGW456L13_1221 at 1364.186 kb on - strand, within PfGW456L13_1221 at 1364.236 kb on + strand, within PfGW456L13_1221 at 1364.236 kb on + strand, within PfGW456L13_1221 at 1364.236 kb on + strand, within PfGW456L13_1221 at 1364.236 kb on + strand, within PfGW456L13_1221 at 1364.237 kb on - strand, within PfGW456L13_1221 at 1364.237 kb on - strand, within PfGW456L13_1221 at 1364.237 kb on - strand, within PfGW456L13_1221 at 1364.308 kb on + strand, within PfGW456L13_1221 at 1364.309 kb on - strand, within PfGW456L13_1221 at 1364.309 kb on - strand, within PfGW456L13_1221 at 1364.312 kb on + strand, within PfGW456L13_1221 at 1364.312 kb on + strand, within PfGW456L13_1221 at 1364.312 kb on + strand, within PfGW456L13_1221 at 1364.312 kb on + strand, within PfGW456L13_1221 at 1364.312 kb on + strand, within PfGW456L13_1221 at 1364.312 kb on + strand, within PfGW456L13_1221 at 1364.312 kb on + strand, within PfGW456L13_1221 at 1364.312 kb on + strand, within PfGW456L13_1221 at 1364.312 kb on + strand, within PfGW456L13_1221 at 1364.313 kb on - strand, within PfGW456L13_1221 at 1364.313 kb on - strand, within PfGW456L13_1221 at 1364.313 kb on - strand, within PfGW456L13_1221 at 1364.313 kb on - strand, within PfGW456L13_1221 at 1364.313 kb on - strand, within PfGW456L13_1221 at 1364.313 kb on - strand, within PfGW456L13_1221 at 1364.313 kb on - strand, within PfGW456L13_1221 at 1364.405 kb on + strand, within PfGW456L13_1221 at 1364.405 kb on + strand, within PfGW456L13_1221 at 1364.405 kb on + strand, within PfGW456L13_1221 at 1364.405 kb on + strand, within PfGW456L13_1221 at 1364.406 kb on - strand, within PfGW456L13_1221 at 1364.440 kb on + strand, within PfGW456L13_1221 at 1364.441 kb on - strand, within PfGW456L13_1221 at 1364.441 kb on - strand, within PfGW456L13_1221 at 1364.467 kb on + strand, within PfGW456L13_1221 at 1364.468 kb on - strand, within PfGW456L13_1221 at 1364.505 kb on + strand, within PfGW456L13_1221 at 1364.505 kb on + strand, within PfGW456L13_1221 at 1364.505 kb on + strand, within PfGW456L13_1221 at 1364.505 kb on + strand, within PfGW456L13_1221 at 1364.506 kb on - strand, within PfGW456L13_1221 at 1364.506 kb on - strand, within PfGW456L13_1221 at 1364.506 kb on - strand, within PfGW456L13_1221 at 1364.506 kb on - strand, within PfGW456L13_1221 at 1364.509 kb on + strand, within PfGW456L13_1221 at 1364.509 kb on + strand, within PfGW456L13_1221 at 1364.510 kb on - strand, within PfGW456L13_1221 at 1364.661 kb on - strand, within PfGW456L13_1221 at 1364.831 kb on + strand, within PfGW456L13_1221 at 1364.831 kb on + strand, within PfGW456L13_1221 at 1364.831 kb on + strand, within PfGW456L13_1221 at 1364.832 kb on - strand, within PfGW456L13_1221 at 1364.832 kb on - strand, within PfGW456L13_1221 at 1364.935 kb on + strand at 1364.972 kb on + strand at 1364.973 kb on - strand at 1364.973 kb on - strand at 1365.027 kb on + strand at 1365.028 kb on - strand at 1365.218 kb on - strand, within PfGW456L13_1222 at 1365.265 kb on + strand, within PfGW456L13_1222 at 1365.286 kb on + strand, within PfGW456L13_1222 at 1365.286 kb on + strand, within PfGW456L13_1222 at 1365.286 kb on + strand, within PfGW456L13_1222 at 1365.287 kb on - strand, within PfGW456L13_1222 at 1365.287 kb on - strand, within PfGW456L13_1222 at 1365.287 kb on - strand, within PfGW456L13_1222 at 1365.688 kb on + strand, within PfGW456L13_1222 at 1365.689 kb on - strand, within PfGW456L13_1222 at 1365.689 kb on - strand, within PfGW456L13_1222 at 1365.689 kb on - strand at 1365.772 kb on - strand at 1365.794 kb on + strand at 1365.795 kb on - strand at 1365.795 kb on - strand at 1365.800 kb on - strand at 1365.800 kb on - strand at 1365.855 kb on + strand at 1365.855 kb on + strand at 1365.856 kb on - strand at 1365.856 kb on - strand at 1365.856 kb on - strand at 1365.906 kb on + strand at 1365.907 kb on - strand at 1365.907 kb on - strand at 1365.907 kb on - strand at 1365.907 kb on - strand at 1365.907 kb on - strand at 1365.907 kb on - strand at 1365.925 kb on + strand at 1365.925 kb on + strand at 1365.925 kb on + strand at 1365.925 kb on + strand at 1365.925 kb on + strand at 1365.925 kb on + strand at 1365.925 kb on + strand at 1365.925 kb on + strand at 1365.925 kb on + strand at 1365.925 kb on + strand at 1365.925 kb on + strand at 1365.926 kb on - strand at 1365.926 kb on - strand at 1365.926 kb on - strand at 1365.926 kb on - strand at 1365.926 kb on - strand at 1365.926 kb on - strand at 1365.926 kb on - strand at 1365.926 kb on - strand at 1365.939 kb on + strand at 1365.939 kb on + strand at 1365.939 kb on + strand at 1365.940 kb on - strand at 1365.940 kb on - strand at 1365.940 kb on - strand at 1365.940 kb on - strand at 1365.944 kb on + strand at 1365.944 kb on + strand at 1365.944 kb on + strand at 1365.945 kb on - strand at 1365.945 kb on - strand at 1365.945 kb on - strand at 1365.945 kb on - strand at 1365.956 kb on + strand at 1365.956 kb on + strand at 1365.956 kb on + strand at 1365.956 kb on + strand at 1365.956 kb on + strand at 1365.956 kb on + strand at 1365.957 kb on - strand at 1365.957 kb on - strand at 1365.957 kb on - strand at 1365.957 kb on - strand at 1366.313 kb on + strand, within PfGW456L13_1223 at 1366.313 kb on + strand, within PfGW456L13_1223 at 1366.313 kb on + strand, within PfGW456L13_1223 at 1366.313 kb on + strand, within PfGW456L13_1223 at 1366.313 kb on + strand, within PfGW456L13_1223 at 1366.313 kb on + strand, within PfGW456L13_1223 at 1366.314 kb on - strand, within PfGW456L13_1223 at 1366.314 kb on - strand, within PfGW456L13_1223 at 1366.658 kb on + strand at 1366.659 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction a-Ketoglutaric (C) remove 1,364,185 + PfGW456L13_1221 0.25 -3.4 1,364,185 + PfGW456L13_1221 0.25 -3.3 1,364,186 - PfGW456L13_1221 0.25 -3.7 1,364,186 - PfGW456L13_1221 0.25 -3.9 1,364,236 + PfGW456L13_1221 0.30 -3.6 1,364,236 + PfGW456L13_1221 0.30 -3.7 1,364,236 + PfGW456L13_1221 0.30 -2.9 1,364,236 + PfGW456L13_1221 0.30 -4.0 1,364,237 - PfGW456L13_1221 0.30 -4.3 1,364,237 - PfGW456L13_1221 0.30 -3.3 1,364,237 - PfGW456L13_1221 0.30 -2.8 1,364,308 + PfGW456L13_1221 0.37 -3.1 1,364,309 - PfGW456L13_1221 0.37 -4.0 1,364,309 - PfGW456L13_1221 0.37 -3.1 1,364,312 + PfGW456L13_1221 0.37 -3.0 1,364,312 + PfGW456L13_1221 0.37 -3.4 1,364,312 + PfGW456L13_1221 0.37 -1.8 1,364,312 + PfGW456L13_1221 0.37 -3.6 1,364,312 + PfGW456L13_1221 0.37 -3.1 1,364,312 + PfGW456L13_1221 0.37 -3.6 1,364,312 + PfGW456L13_1221 0.37 -4.9 1,364,312 + PfGW456L13_1221 0.37 -3.7 1,364,312 + PfGW456L13_1221 0.37 -4.1 1,364,313 - PfGW456L13_1221 0.38 -4.6 1,364,313 - PfGW456L13_1221 0.38 -1.2 1,364,313 - PfGW456L13_1221 0.38 -4.3 1,364,313 - PfGW456L13_1221 0.38 -2.9 1,364,313 - PfGW456L13_1221 0.38 -4.1 1,364,313 - PfGW456L13_1221 0.38 -2.9 1,364,313 - PfGW456L13_1221 0.38 -3.2 1,364,405 + PfGW456L13_1221 0.46 -3.5 1,364,405 + PfGW456L13_1221 0.46 -4.9 1,364,405 + PfGW456L13_1221 0.46 -0.3 1,364,405 + PfGW456L13_1221 0.46 -3.1 1,364,406 - PfGW456L13_1221 0.46 -4.5 1,364,440 + PfGW456L13_1221 0.50 -3.6 1,364,441 - PfGW456L13_1221 0.50 -2.8 1,364,441 - PfGW456L13_1221 0.50 -2.3 1,364,467 + PfGW456L13_1221 0.52 -2.2 1,364,468 - PfGW456L13_1221 0.52 -3.6 1,364,505 + PfGW456L13_1221 0.56 -4.2 1,364,505 + PfGW456L13_1221 0.56 -0.4 1,364,505 + PfGW456L13_1221 0.56 -1.7 1,364,505 + PfGW456L13_1221 0.56 -4.1 1,364,506 - PfGW456L13_1221 0.56 -3.3 1,364,506 - PfGW456L13_1221 0.56 -3.5 1,364,506 - PfGW456L13_1221 0.56 -2.6 1,364,506 - PfGW456L13_1221 0.56 -2.1 1,364,509 + PfGW456L13_1221 0.56 -4.8 1,364,509 + PfGW456L13_1221 0.56 -4.1 1,364,510 - PfGW456L13_1221 0.56 -4.2 1,364,661 - PfGW456L13_1221 0.71 -4.1 1,364,831 + PfGW456L13_1221 0.87 -5.1 1,364,831 + PfGW456L13_1221 0.87 -3.5 1,364,831 + PfGW456L13_1221 0.87 -1.0 1,364,832 - PfGW456L13_1221 0.87 -4.4 1,364,832 - PfGW456L13_1221 0.87 -4.4 1,364,935 + -3.9 1,364,972 + -3.8 1,364,973 - -2.5 1,364,973 - -3.1 1,365,027 + -3.0 1,365,028 - -3.2 1,365,218 - PfGW456L13_1222 0.30 -2.3 1,365,265 + PfGW456L13_1222 0.36 -3.8 1,365,286 + PfGW456L13_1222 0.38 -2.8 1,365,286 + PfGW456L13_1222 0.38 -2.6 1,365,286 + PfGW456L13_1222 0.38 -2.3 1,365,287 - PfGW456L13_1222 0.38 -2.3 1,365,287 - PfGW456L13_1222 0.38 -3.2 1,365,287 - PfGW456L13_1222 0.38 -2.8 1,365,688 + PfGW456L13_1222 0.86 -3.9 1,365,689 - PfGW456L13_1222 0.86 -3.4 1,365,689 - PfGW456L13_1222 0.86 -1.7 1,365,689 - +0.2 1,365,772 - +2.5 1,365,794 + +1.0 1,365,795 - -2.6 1,365,795 - -3.0 1,365,800 - -0.0 1,365,800 - +1.2 1,365,855 + +0.1 1,365,855 + -2.1 1,365,856 - -1.8 1,365,856 - -1.9 1,365,856 - -2.6 1,365,906 + +1.1 1,365,907 - -2.9 1,365,907 - +0.8 1,365,907 - -1.2 1,365,907 - -0.4 1,365,907 - +0.1 1,365,907 - -1.8 1,365,925 + -1.2 1,365,925 + +2.0 1,365,925 + -1.2 1,365,925 + +0.3 1,365,925 + +1.6 1,365,925 + +1.7 1,365,925 + -0.0 1,365,925 + +1.3 1,365,925 + +2.4 1,365,925 + -0.3 1,365,925 + -0.0 1,365,926 - +1.3 1,365,926 - -0.8 1,365,926 - -1.2 1,365,926 - -1.2 1,365,926 - -0.8 1,365,926 - +0.7 1,365,926 - +2.0 1,365,926 - -1.6 1,365,939 + -1.8 1,365,939 + +0.7 1,365,939 + +1.8 1,365,940 - +2.5 1,365,940 - -2.1 1,365,940 - +0.4 1,365,940 - +0.2 1,365,944 + -0.2 1,365,944 + -0.1 1,365,944 + +0.7 1,365,945 - +0.5 1,365,945 - +1.6 1,365,945 - +0.2 1,365,945 - +1.1 1,365,956 + +2.0 1,365,956 + -3.3 1,365,956 + -1.9 1,365,956 + +0.7 1,365,956 + -0.8 1,365,956 + +2.0 1,365,957 - +2.7 1,365,957 - -3.2 1,365,957 - +1.2 1,365,957 - -1.3 1,366,313 + PfGW456L13_1223 0.52 +3.3 1,366,313 + PfGW456L13_1223 0.52 +3.8 1,366,313 + PfGW456L13_1223 0.52 +0.8 1,366,313 + PfGW456L13_1223 0.52 +0.9 1,366,313 + PfGW456L13_1223 0.52 +1.9 1,366,313 + PfGW456L13_1223 0.52 -1.2 1,366,314 - PfGW456L13_1223 0.53 -2.1 1,366,314 - PfGW456L13_1223 0.53 +1.1 1,366,658 + -0.1 1,366,659 - +0.9
Or see this region's nucleotide sequence