Experiment: Cisplatin 0.1 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt creC and creD are separated by 57 nucleotides creD and arcA are separated by 59 nucleotides arcA and yjjY are separated by 95 nucleotides
b4399: creC - sensory histidine kinase in two-component regulatory system with CreB or PhoB, regulator of the CreBC regulon (NCBI), at 4,634,719 to 4,636,143
creC
b4400: creD - inner membrane protein (NCBI), at 4,636,201 to 4,637,553
creD
b4401: arcA - DNA-binding response regulator in two-component regulatory system with ArcB or CpxA (NCBI), at 4,637,613 to 4,638,329
arcA
b4402: yjjY - hypothetical protein (NCBI), at 4,638,425 to 4,638,565
yjjY
Position (kb)
4636
4637
4638 Strain fitness (log2 ratio)
-2
-1
0
1
2
3 at 4635.327 kb on + strand, within creC at 4635.334 kb on + strand, within creC at 4635.344 kb on + strand, within creC at 4635.392 kb on - strand, within creC at 4635.392 kb on - strand, within creC at 4635.416 kb on + strand, within creC at 4635.434 kb on - strand, within creC at 4635.450 kb on + strand, within creC at 4635.667 kb on - strand, within creC at 4635.667 kb on - strand, within creC at 4635.720 kb on - strand, within creC at 4635.936 kb on - strand, within creC at 4635.936 kb on - strand, within creC at 4635.949 kb on + strand, within creC at 4635.949 kb on + strand, within creC at 4636.211 kb on - strand at 4636.218 kb on + strand at 4636.249 kb on + strand at 4636.252 kb on - strand at 4636.327 kb on - strand at 4636.329 kb on - strand at 4636.382 kb on - strand, within creD at 4636.408 kb on + strand, within creD at 4636.480 kb on + strand, within creD at 4636.480 kb on + strand, within creD at 4636.481 kb on - strand, within creD at 4636.489 kb on + strand, within creD at 4636.494 kb on - strand, within creD at 4636.514 kb on - strand, within creD at 4636.534 kb on + strand, within creD at 4636.534 kb on + strand, within creD at 4636.655 kb on + strand, within creD at 4636.688 kb on + strand, within creD at 4636.688 kb on + strand, within creD at 4636.688 kb on + strand, within creD at 4636.725 kb on - strand, within creD at 4636.737 kb on + strand, within creD at 4636.743 kb on + strand, within creD at 4636.743 kb on + strand, within creD at 4636.745 kb on - strand, within creD at 4636.773 kb on - strand, within creD at 4636.773 kb on - strand, within creD at 4636.835 kb on + strand, within creD at 4636.835 kb on + strand, within creD at 4636.909 kb on - strand, within creD at 4637.105 kb on + strand, within creD at 4637.105 kb on + strand, within creD at 4637.158 kb on + strand, within creD at 4637.158 kb on + strand, within creD at 4637.168 kb on - strand, within creD at 4637.178 kb on - strand, within creD at 4637.200 kb on - strand, within creD at 4637.200 kb on - strand, within creD at 4637.236 kb on - strand, within creD at 4637.253 kb on + strand, within creD at 4637.253 kb on + strand, within creD at 4637.259 kb on + strand, within creD at 4637.277 kb on - strand, within creD at 4637.277 kb on - strand, within creD at 4637.302 kb on - strand, within creD at 4637.321 kb on + strand, within creD at 4637.321 kb on - strand, within creD at 4637.350 kb on + strand, within creD at 4637.385 kb on + strand, within creD at 4637.385 kb on + strand, within creD at 4637.390 kb on + strand, within creD at 4637.418 kb on + strand at 4637.462 kb on + strand at 4637.463 kb on + strand at 4638.330 kb on - strand at 4638.434 kb on + strand at 4638.491 kb on + strand, within yjjY at 4638.491 kb on + strand, within yjjY
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.1 mg/ml remove 4,635,327 + creC b4399 0.43 -1.3 4,635,334 + creC b4399 0.43 +0.8 4,635,344 + creC b4399 0.44 -1.3 4,635,392 - creC b4399 0.47 +0.4 4,635,392 - creC b4399 0.47 -1.9 4,635,416 + creC b4399 0.49 -0.9 4,635,434 - creC b4399 0.50 -0.4 4,635,450 + creC b4399 0.51 -1.9 4,635,667 - creC b4399 0.67 +0.5 4,635,667 - creC b4399 0.67 +1.0 4,635,720 - creC b4399 0.70 +0.9 4,635,936 - creC b4399 0.85 +0.2 4,635,936 - creC b4399 0.85 -0.4 4,635,949 + creC b4399 0.86 -1.4 4,635,949 + creC b4399 0.86 +2.8 4,636,211 - +0.7 4,636,218 + -0.6 4,636,249 + +1.6 4,636,252 - -0.2 4,636,327 - -0.2 4,636,329 - -1.1 4,636,382 - creD b4400 0.13 +1.5 4,636,408 + creD b4400 0.15 -1.9 4,636,480 + creD b4400 0.21 -1.6 4,636,480 + creD b4400 0.21 -0.6 4,636,481 - creD b4400 0.21 -0.0 4,636,489 + creD b4400 0.21 -0.3 4,636,494 - creD b4400 0.22 +1.0 4,636,514 - creD b4400 0.23 +0.7 4,636,534 + creD b4400 0.25 +1.4 4,636,534 + creD b4400 0.25 +3.0 4,636,655 + creD b4400 0.34 +3.2 4,636,688 + creD b4400 0.36 -1.9 4,636,688 + creD b4400 0.36 -1.4 4,636,688 + creD b4400 0.36 -1.4 4,636,725 - creD b4400 0.39 +1.9 4,636,737 + creD b4400 0.40 -0.9 4,636,743 + creD b4400 0.40 +0.1 4,636,743 + creD b4400 0.40 +3.4 4,636,745 - creD b4400 0.40 +1.4 4,636,773 - creD b4400 0.42 +1.0 4,636,773 - creD b4400 0.42 -0.2 4,636,835 + creD b4400 0.47 +0.1 4,636,835 + creD b4400 0.47 +1.9 4,636,909 - creD b4400 0.52 -0.2 4,637,105 + creD b4400 0.67 -1.2 4,637,105 + creD b4400 0.67 +0.4 4,637,158 + creD b4400 0.71 +1.0 4,637,158 + creD b4400 0.71 -0.0 4,637,168 - creD b4400 0.71 -0.6 4,637,178 - creD b4400 0.72 +0.1 4,637,200 - creD b4400 0.74 +0.1 4,637,200 - creD b4400 0.74 -0.9 4,637,236 - creD b4400 0.76 +1.0 4,637,253 + creD b4400 0.78 +1.9 4,637,253 + creD b4400 0.78 -0.8 4,637,259 + creD b4400 0.78 +0.6 4,637,277 - creD b4400 0.80 +0.4 4,637,277 - creD b4400 0.80 -0.2 4,637,302 - creD b4400 0.81 +0.4 4,637,321 + creD b4400 0.83 -0.2 4,637,321 - creD b4400 0.83 +2.2 4,637,350 + creD b4400 0.85 +0.4 4,637,385 + creD b4400 0.88 +0.4 4,637,385 + creD b4400 0.88 -0.6 4,637,390 + creD b4400 0.88 +0.3 4,637,418 + +1.4 4,637,462 + -0.4 4,637,463 + +1.6 4,638,330 - -1.0 4,638,434 + -1.4 4,638,491 + yjjY b4402 0.47 -1.2 4,638,491 + yjjY b4402 0.47 -1.6
Or see this region's nucleotide sequence