Experiment: Cisplatin 0.1 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt fdhE and fdoI overlap by 4 nucleotides fdoI and fdoH overlap by 4 nucleotides fdoH and fdoG are separated by 12 nucleotides
b3891: fdhE - formate dehydrogenase accessory protein FdhE (NCBI), at 4,078,322 to 4,079,251
fdhE
b3892: fdoI - formate dehydrogenase-O, cytochrome b556 subunit (NCBI), at 4,079,248 to 4,079,883
fdoI
b3893: fdoH - formate dehydrogenase-O, Fe-S subunit (NCBI), at 4,079,880 to 4,080,782
fdoH
b3894: fdoG - formate dehydrogenase-O, large subunit (NCBI), at 4,080,795 to 4,083,845
fdoG
Position (kb)
4079
4080
4081 Strain fitness (log2 ratio)
-1
0
1
2
3
4
5
6
7 at 4078.981 kb on - strand, within fdhE at 4078.981 kb on - strand, within fdhE at 4078.991 kb on - strand, within fdhE at 4079.019 kb on + strand, within fdhE at 4079.038 kb on - strand, within fdhE at 4079.042 kb on + strand, within fdhE at 4079.058 kb on + strand, within fdhE at 4079.064 kb on - strand, within fdhE at 4079.092 kb on + strand, within fdhE at 4079.120 kb on - strand, within fdhE at 4079.195 kb on - strand at 4079.195 kb on - strand at 4079.195 kb on - strand at 4079.198 kb on - strand at 4079.280 kb on + strand at 4079.291 kb on - strand at 4079.295 kb on - strand at 4079.295 kb on - strand at 4079.309 kb on - strand at 4079.325 kb on + strand, within fdoI at 4079.325 kb on - strand, within fdoI at 4079.325 kb on - strand, within fdoI at 4079.340 kb on - strand, within fdoI at 4079.343 kb on - strand, within fdoI at 4079.380 kb on + strand, within fdoI at 4079.380 kb on + strand, within fdoI at 4079.380 kb on + strand, within fdoI at 4079.388 kb on - strand, within fdoI at 4079.388 kb on - strand, within fdoI at 4079.438 kb on - strand, within fdoI at 4079.581 kb on - strand, within fdoI at 4079.581 kb on - strand, within fdoI at 4079.581 kb on - strand, within fdoI at 4079.581 kb on - strand, within fdoI at 4079.586 kb on - strand, within fdoI at 4079.626 kb on + strand, within fdoI at 4079.654 kb on - strand, within fdoI at 4079.654 kb on - strand, within fdoI at 4079.665 kb on - strand, within fdoI at 4079.665 kb on - strand, within fdoI at 4079.680 kb on - strand, within fdoI at 4079.689 kb on + strand, within fdoI at 4079.741 kb on + strand, within fdoI at 4079.761 kb on + strand, within fdoI at 4079.766 kb on - strand, within fdoI at 4079.769 kb on - strand, within fdoI at 4079.769 kb on - strand, within fdoI at 4079.818 kb on - strand, within fdoI at 4079.832 kb on - strand at 4079.903 kb on - strand at 4079.903 kb on - strand at 4079.930 kb on - strand at 4079.930 kb on - strand at 4079.937 kb on + strand at 4079.945 kb on - strand at 4079.945 kb on - strand at 4079.945 kb on - strand at 4079.945 kb on - strand at 4079.960 kb on - strand at 4079.965 kb on + strand at 4079.999 kb on - strand, within fdoH at 4079.999 kb on - strand, within fdoH at 4080.077 kb on - strand, within fdoH at 4080.096 kb on + strand, within fdoH at 4080.096 kb on + strand, within fdoH at 4080.096 kb on + strand, within fdoH at 4080.104 kb on + strand, within fdoH at 4080.104 kb on - strand, within fdoH at 4080.105 kb on - strand, within fdoH at 4080.121 kb on - strand, within fdoH at 4080.138 kb on + strand, within fdoH at 4080.141 kb on + strand, within fdoH at 4080.165 kb on - strand, within fdoH at 4080.169 kb on + strand, within fdoH at 4080.278 kb on + strand, within fdoH at 4080.288 kb on + strand, within fdoH at 4080.299 kb on + strand, within fdoH at 4080.299 kb on + strand, within fdoH at 4080.345 kb on + strand, within fdoH at 4080.394 kb on + strand, within fdoH at 4080.395 kb on - strand, within fdoH at 4080.410 kb on - strand, within fdoH at 4080.415 kb on + strand, within fdoH at 4080.415 kb on + strand, within fdoH at 4080.460 kb on - strand, within fdoH at 4080.460 kb on - strand, within fdoH at 4080.462 kb on + strand, within fdoH at 4080.480 kb on - strand, within fdoH at 4080.486 kb on - strand, within fdoH at 4080.486 kb on - strand, within fdoH at 4080.540 kb on + strand, within fdoH at 4080.548 kb on - strand, within fdoH at 4080.571 kb on + strand, within fdoH at 4080.582 kb on + strand, within fdoH at 4080.582 kb on + strand, within fdoH at 4080.598 kb on - strand, within fdoH at 4080.598 kb on - strand, within fdoH at 4080.598 kb on - strand, within fdoH at 4080.608 kb on + strand, within fdoH at 4080.632 kb on - strand, within fdoH at 4080.649 kb on - strand, within fdoH at 4080.653 kb on + strand, within fdoH at 4080.653 kb on + strand, within fdoH at 4080.670 kb on + strand, within fdoH at 4080.670 kb on + strand, within fdoH at 4080.707 kb on - strand at 4080.707 kb on - strand at 4080.786 kb on - strand at 4080.786 kb on - strand at 4080.792 kb on + strand at 4080.831 kb on - strand at 4080.842 kb on + strand at 4080.864 kb on - strand at 4080.904 kb on + strand at 4080.926 kb on + strand at 4081.022 kb on - strand at 4081.022 kb on - strand at 4081.025 kb on + strand at 4081.038 kb on + strand at 4081.038 kb on + strand at 4081.041 kb on - strand at 4081.041 kb on - strand at 4081.047 kb on - strand at 4081.123 kb on + strand, within fdoG at 4081.123 kb on + strand, within fdoG at 4081.189 kb on + strand, within fdoG at 4081.189 kb on + strand, within fdoG at 4081.189 kb on + strand, within fdoG at 4081.194 kb on + strand, within fdoG at 4081.315 kb on + strand, within fdoG at 4081.315 kb on + strand, within fdoG at 4081.321 kb on + strand, within fdoG at 4081.323 kb on + strand, within fdoG at 4081.416 kb on + strand, within fdoG at 4081.438 kb on - strand, within fdoG at 4081.443 kb on - strand, within fdoG at 4081.443 kb on - strand, within fdoG at 4081.468 kb on + strand, within fdoG at 4081.482 kb on - strand, within fdoG at 4081.537 kb on - strand, within fdoG at 4081.545 kb on + strand, within fdoG at 4081.576 kb on + strand, within fdoG at 4081.612 kb on - strand, within fdoG at 4081.612 kb on - strand, within fdoG at 4081.620 kb on - strand, within fdoG at 4081.646 kb on - strand, within fdoG at 4081.652 kb on - strand, within fdoG at 4081.654 kb on - strand, within fdoG at 4081.654 kb on - strand, within fdoG at 4081.687 kb on - strand, within fdoG at 4081.753 kb on - strand, within fdoG at 4081.753 kb on - strand, within fdoG
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.1 mg/ml remove 4,078,981 - fdhE b3891 0.71 -1.1 4,078,981 - fdhE b3891 0.71 -0.9 4,078,991 - fdhE b3891 0.72 +0.7 4,079,019 + fdhE b3891 0.75 +2.3 4,079,038 - fdhE b3891 0.77 -1.6 4,079,042 + fdhE b3891 0.77 +1.6 4,079,058 + fdhE b3891 0.79 -0.5 4,079,064 - fdhE b3891 0.80 +1.2 4,079,092 + fdhE b3891 0.83 +1.7 4,079,120 - fdhE b3891 0.86 -0.2 4,079,195 - +1.5 4,079,195 - -1.1 4,079,195 - +1.2 4,079,198 - +1.9 4,079,280 + +1.4 4,079,291 - +1.7 4,079,295 - -0.5 4,079,295 - +1.8 4,079,309 - +2.1 4,079,325 + fdoI b3892 0.12 +1.3 4,079,325 - fdoI b3892 0.12 +2.2 4,079,325 - fdoI b3892 0.12 +4.3 4,079,340 - fdoI b3892 0.14 +0.2 4,079,343 - fdoI b3892 0.15 +1.2 4,079,380 + fdoI b3892 0.21 -1.6 4,079,380 + fdoI b3892 0.21 +1.2 4,079,380 + fdoI b3892 0.21 -1.0 4,079,388 - fdoI b3892 0.22 +1.5 4,079,388 - fdoI b3892 0.22 +4.0 4,079,438 - fdoI b3892 0.30 +1.0 4,079,581 - fdoI b3892 0.52 +2.3 4,079,581 - fdoI b3892 0.52 -0.5 4,079,581 - fdoI b3892 0.52 +2.2 4,079,581 - fdoI b3892 0.52 +1.8 4,079,586 - fdoI b3892 0.53 +2.3 4,079,626 + fdoI b3892 0.59 +0.3 4,079,654 - fdoI b3892 0.64 -0.1 4,079,654 - fdoI b3892 0.64 +2.6 4,079,665 - fdoI b3892 0.66 -0.8 4,079,665 - fdoI b3892 0.66 +0.1 4,079,680 - fdoI b3892 0.68 +0.7 4,079,689 + fdoI b3892 0.69 +0.2 4,079,741 + fdoI b3892 0.78 -0.3 4,079,761 + fdoI b3892 0.81 +1.5 4,079,766 - fdoI b3892 0.81 +1.7 4,079,769 - fdoI b3892 0.82 +2.8 4,079,769 - fdoI b3892 0.82 +0.1 4,079,818 - fdoI b3892 0.90 +1.2 4,079,832 - +2.7 4,079,903 - +0.5 4,079,903 - +1.3 4,079,930 - +1.3 4,079,930 - +0.2 4,079,937 + +2.7 4,079,945 - +0.8 4,079,945 - +2.5 4,079,945 - +1.1 4,079,945 - +2.8 4,079,960 - +1.0 4,079,965 + +1.2 4,079,999 - fdoH b3893 0.13 +2.5 4,079,999 - fdoH b3893 0.13 +0.2 4,080,077 - fdoH b3893 0.22 +1.9 4,080,096 + fdoH b3893 0.24 -0.3 4,080,096 + fdoH b3893 0.24 +0.1 4,080,096 + fdoH b3893 0.24 +1.2 4,080,104 + fdoH b3893 0.25 -0.1 4,080,104 - fdoH b3893 0.25 +2.3 4,080,105 - fdoH b3893 0.25 +1.0 4,080,121 - fdoH b3893 0.27 +0.4 4,080,138 + fdoH b3893 0.29 +1.2 4,080,141 + fdoH b3893 0.29 +2.0 4,080,165 - fdoH b3893 0.32 +0.9 4,080,169 + fdoH b3893 0.32 +6.9 4,080,278 + fdoH b3893 0.44 +4.3 4,080,288 + fdoH b3893 0.45 +0.7 4,080,299 + fdoH b3893 0.46 +2.2 4,080,299 + fdoH b3893 0.46 +2.1 4,080,345 + fdoH b3893 0.51 +0.2 4,080,394 + fdoH b3893 0.57 +1.8 4,080,395 - fdoH b3893 0.57 +2.1 4,080,410 - fdoH b3893 0.59 -0.1 4,080,415 + fdoH b3893 0.59 -0.5 4,080,415 + fdoH b3893 0.59 -0.1 4,080,460 - fdoH b3893 0.64 +0.5 4,080,460 - fdoH b3893 0.64 +2.7 4,080,462 + fdoH b3893 0.64 +2.8 4,080,480 - fdoH b3893 0.66 +0.5 4,080,486 - fdoH b3893 0.67 -0.8 4,080,486 - fdoH b3893 0.67 -0.1 4,080,540 + fdoH b3893 0.73 +2.4 4,080,548 - fdoH b3893 0.74 +0.3 4,080,571 + fdoH b3893 0.77 -0.8 4,080,582 + fdoH b3893 0.78 +1.5 4,080,582 + fdoH b3893 0.78 +0.3 4,080,598 - fdoH b3893 0.80 +0.9 4,080,598 - fdoH b3893 0.80 +1.2 4,080,598 - fdoH b3893 0.80 +0.4 4,080,608 + fdoH b3893 0.81 +1.3 4,080,632 - fdoH b3893 0.83 +0.3 4,080,649 - fdoH b3893 0.85 +2.9 4,080,653 + fdoH b3893 0.86 +3.7 4,080,653 + fdoH b3893 0.86 +2.2 4,080,670 + fdoH b3893 0.87 +0.8 4,080,670 + fdoH b3893 0.87 -0.7 4,080,707 - -1.5 4,080,707 - +3.2 4,080,786 - +1.2 4,080,786 - +0.5 4,080,792 + +0.7 4,080,831 - +0.5 4,080,842 + +2.4 4,080,864 - -0.3 4,080,904 + +3.8 4,080,926 + +1.7 4,081,022 - +0.1 4,081,022 - +1.3 4,081,025 + +0.3 4,081,038 + +1.8 4,081,038 + +0.5 4,081,041 - +1.9 4,081,041 - +2.3 4,081,047 - +1.3 4,081,123 + fdoG b3894 0.11 -0.2 4,081,123 + fdoG b3894 0.11 +1.3 4,081,189 + fdoG b3894 0.13 +2.1 4,081,189 + fdoG b3894 0.13 +3.5 4,081,189 + fdoG b3894 0.13 +4.0 4,081,194 + fdoG b3894 0.13 +1.1 4,081,315 + fdoG b3894 0.17 +1.3 4,081,315 + fdoG b3894 0.17 +1.5 4,081,321 + fdoG b3894 0.17 +1.8 4,081,323 + fdoG b3894 0.17 +1.6 4,081,416 + fdoG b3894 0.20 +3.7 4,081,438 - fdoG b3894 0.21 +0.5 4,081,443 - fdoG b3894 0.21 -0.3 4,081,443 - fdoG b3894 0.21 -0.5 4,081,468 + fdoG b3894 0.22 +1.4 4,081,482 - fdoG b3894 0.23 +1.5 4,081,537 - fdoG b3894 0.24 +2.4 4,081,545 + fdoG b3894 0.25 +1.1 4,081,576 + fdoG b3894 0.26 +2.0 4,081,612 - fdoG b3894 0.27 -0.7 4,081,612 - fdoG b3894 0.27 -1.1 4,081,620 - fdoG b3894 0.27 +0.5 4,081,646 - fdoG b3894 0.28 -0.3 4,081,652 - fdoG b3894 0.28 +3.5 4,081,654 - fdoG b3894 0.28 +3.6 4,081,654 - fdoG b3894 0.28 +1.9 4,081,687 - fdoG b3894 0.29 +2.2 4,081,753 - fdoG b3894 0.31 +1.1 4,081,753 - fdoG b3894 0.31 +1.0
Or see this region's nucleotide sequence