Experiment: Cisplatin 0.1 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt fes and ybdZ are separated by 2 nucleotides ybdZ and entF overlap by 4 nucleotides entF and fepE are separated by 215 nucleotides
b0585: fes - enterobactin/ferric enterobactin esterase (NCBI), at 612,038 to 613,162
fes
b4511: ybdZ - hypothetical protein (NCBI), at 613,165 to 613,383
ybdZ
b0586: entF - enterobactin synthase multienzyme complex component, ATP-dependent (NCBI), at 613,380 to 617,261
entF
b0587: fepE - regulator of length of O-antigen component of lipopolysaccharide chains (NCBI), at 617,477 to 618,610
fepE
Position (kb) 613
614
615
616
617
618 Strain fitness (log2 ratio) -3
-2
-1
0
1
2
3 at 612.424 kb on + strand, within fes at 612.424 kb on + strand, within fes at 612.629 kb on - strand, within fes at 612.629 kb on - strand, within fes at 612.676 kb on - strand, within fes at 612.835 kb on + strand, within fes at 612.840 kb on + strand, within fes at 612.843 kb on - strand, within fes at 612.843 kb on - strand, within fes at 612.868 kb on - strand, within fes at 612.869 kb on - strand, within fes at 612.869 kb on - strand, within fes at 612.871 kb on + strand, within fes at 612.883 kb on + strand, within fes at 612.960 kb on - strand, within fes at 613.018 kb on + strand, within fes at 613.018 kb on + strand, within fes at 613.181 kb on - strand at 613.181 kb on - strand at 613.203 kb on + strand, within ybdZ at 613.270 kb on + strand, within ybdZ at 613.340 kb on + strand, within ybdZ at 613.396 kb on - strand at 613.455 kb on + strand at 613.455 kb on + strand at 613.523 kb on + strand at 613.523 kb on + strand at 613.549 kb on - strand at 613.549 kb on - strand at 613.589 kb on + strand at 613.643 kb on + strand at 613.663 kb on + strand at 613.663 kb on + strand at 613.663 kb on + strand at 613.671 kb on - strand at 613.671 kb on - strand at 613.870 kb on - strand, within entF at 613.923 kb on + strand, within entF at 613.923 kb on + strand, within entF at 613.927 kb on - strand, within entF at 613.974 kb on + strand, within entF at 614.028 kb on - strand, within entF at 614.050 kb on - strand, within entF at 614.050 kb on - strand, within entF at 614.181 kb on - strand, within entF at 614.181 kb on - strand, within entF at 614.216 kb on + strand, within entF at 614.216 kb on + strand, within entF at 614.421 kb on + strand, within entF at 614.517 kb on - strand, within entF at 614.517 kb on - strand, within entF at 614.517 kb on - strand, within entF at 614.631 kb on + strand, within entF at 614.665 kb on - strand, within entF at 614.665 kb on - strand, within entF at 614.711 kb on + strand, within entF at 614.716 kb on + strand, within entF at 614.716 kb on + strand, within entF at 614.886 kb on + strand, within entF at 614.910 kb on + strand, within entF at 614.969 kb on + strand, within entF at 614.977 kb on - strand, within entF at 614.993 kb on - strand, within entF at 615.069 kb on - strand, within entF at 615.121 kb on + strand, within entF at 615.126 kb on + strand, within entF at 615.369 kb on - strand, within entF at 615.593 kb on - strand, within entF at 615.600 kb on + strand, within entF at 615.600 kb on + strand, within entF at 615.688 kb on - strand, within entF at 615.726 kb on + strand, within entF at 615.879 kb on - strand, within entF at 615.881 kb on - strand, within entF at 616.125 kb on + strand, within entF at 616.185 kb on - strand, within entF at 616.185 kb on - strand, within entF at 616.203 kb on + strand, within entF at 616.211 kb on + strand, within entF at 616.529 kb on + strand, within entF at 616.529 kb on + strand, within entF at 616.645 kb on + strand, within entF at 616.779 kb on - strand, within entF at 616.779 kb on - strand, within entF at 616.793 kb on - strand, within entF at 616.814 kb on + strand, within entF at 616.868 kb on + strand, within entF at 616.988 kb on - strand at 616.993 kb on - strand at 617.023 kb on - strand at 617.024 kb on + strand at 617.024 kb on + strand at 617.038 kb on - strand at 617.048 kb on + strand at 617.066 kb on - strand at 617.120 kb on + strand at 617.121 kb on + strand at 617.122 kb on + strand at 617.133 kb on + strand at 617.135 kb on - strand at 617.136 kb on - strand at 617.136 kb on - strand at 617.138 kb on + strand at 617.146 kb on - strand at 617.155 kb on + strand at 617.160 kb on - strand at 617.162 kb on + strand at 617.162 kb on + strand at 617.162 kb on + strand at 617.166 kb on + strand at 617.168 kb on + strand at 617.168 kb on - strand at 617.170 kb on + strand at 617.175 kb on + strand at 617.175 kb on + strand at 617.181 kb on + strand at 617.181 kb on + strand at 617.182 kb on + strand at 617.183 kb on - strand at 617.195 kb on + strand at 617.206 kb on + strand at 617.206 kb on + strand at 617.206 kb on + strand at 617.206 kb on + strand at 617.206 kb on + strand at 617.206 kb on + strand at 617.235 kb on + strand at 617.247 kb on + strand at 617.272 kb on + strand at 617.587 kb on - strand at 617.616 kb on + strand, within fepE at 617.644 kb on - strand, within fepE at 617.644 kb on - strand, within fepE at 617.644 kb on - strand, within fepE at 617.701 kb on - strand, within fepE at 617.755 kb on - strand, within fepE at 617.849 kb on + strand, within fepE at 617.893 kb on + strand, within fepE at 617.893 kb on + strand, within fepE at 617.947 kb on - strand, within fepE at 617.985 kb on - strand, within fepE at 617.985 kb on - strand, within fepE at 617.986 kb on - strand, within fepE at 618.013 kb on + strand, within fepE at 618.013 kb on + strand, within fepE at 618.018 kb on + strand, within fepE at 618.018 kb on + strand, within fepE at 618.029 kb on - strand, within fepE at 618.035 kb on + strand, within fepE at 618.035 kb on + strand, within fepE at 618.035 kb on + strand, within fepE at 618.045 kb on + strand, within fepE at 618.045 kb on + strand, within fepE at 618.053 kb on - strand, within fepE at 618.071 kb on + strand, within fepE at 618.082 kb on + strand, within fepE at 618.104 kb on + strand, within fepE at 618.104 kb on + strand, within fepE at 618.114 kb on + strand, within fepE at 618.120 kb on - strand, within fepE at 618.151 kb on - strand, within fepE at 618.151 kb on - strand, within fepE at 618.190 kb on + strand, within fepE at 618.250 kb on - strand, within fepE
Per-strain Table
Position Strand Gene LocusTag Fraction Cisplatin 0.1 mg/ml remove 612,424 + fes b0585 0.34 -0.4 612,424 + fes b0585 0.34 -1.9 612,629 - fes b0585 0.53 -0.8 612,629 - fes b0585 0.53 +0.8 612,676 - fes b0585 0.57 +1.9 612,835 + fes b0585 0.71 +1.5 612,840 + fes b0585 0.71 +1.2 612,843 - fes b0585 0.72 -1.4 612,843 - fes b0585 0.72 +1.2 612,868 - fes b0585 0.74 -1.9 612,869 - fes b0585 0.74 +0.6 612,869 - fes b0585 0.74 +0.7 612,871 + fes b0585 0.74 -0.8 612,883 + fes b0585 0.75 -0.8 612,960 - fes b0585 0.82 -1.8 613,018 + fes b0585 0.87 +1.2 613,018 + fes b0585 0.87 +1.4 613,181 - +0.5 613,181 - +1.1 613,203 + ybdZ b4511 0.17 +0.2 613,270 + ybdZ b4511 0.48 +0.4 613,340 + ybdZ b4511 0.80 +0.9 613,396 - -0.8 613,455 + -1.4 613,455 + -0.4 613,523 + +1.2 613,523 + -1.4 613,549 - -0.5 613,549 - +0.7 613,589 + +1.7 613,643 + +1.0 613,663 + +0.7 613,663 + +0.2 613,663 + +2.1 613,671 - +0.1 613,671 - -2.6 613,870 - entF b0586 0.13 +1.2 613,923 + entF b0586 0.14 +1.7 613,923 + entF b0586 0.14 +1.2 613,927 - entF b0586 0.14 +1.5 613,974 + entF b0586 0.15 +0.2 614,028 - entF b0586 0.17 -1.2 614,050 - entF b0586 0.17 -1.6 614,050 - entF b0586 0.17 +0.4 614,181 - entF b0586 0.21 -0.2 614,181 - entF b0586 0.21 +1.8 614,216 + entF b0586 0.22 +0.2 614,216 + entF b0586 0.22 +0.6 614,421 + entF b0586 0.27 +1.3 614,517 - entF b0586 0.29 +2.1 614,517 - entF b0586 0.29 +1.7 614,517 - entF b0586 0.29 -1.1 614,631 + entF b0586 0.32 -0.9 614,665 - entF b0586 0.33 +3.4 614,665 - entF b0586 0.33 +0.3 614,711 + entF b0586 0.34 -2.7 614,716 + entF b0586 0.34 -0.7 614,716 + entF b0586 0.34 +0.0 614,886 + entF b0586 0.39 +1.1 614,910 + entF b0586 0.39 -0.8 614,969 + entF b0586 0.41 -1.5 614,977 - entF b0586 0.41 +0.8 614,993 - entF b0586 0.42 -0.4 615,069 - entF b0586 0.44 +2.9 615,121 + entF b0586 0.45 +2.0 615,126 + entF b0586 0.45 -0.0 615,369 - entF b0586 0.51 +1.2 615,593 - entF b0586 0.57 +1.2 615,600 + entF b0586 0.57 -0.1 615,600 + entF b0586 0.57 -1.6 615,688 - entF b0586 0.59 +3.2 615,726 + entF b0586 0.60 -0.3 615,879 - entF b0586 0.64 +2.6 615,881 - entF b0586 0.64 -1.4 616,125 + entF b0586 0.71 -1.9 616,185 - entF b0586 0.72 +0.6 616,185 - entF b0586 0.72 -1.9 616,203 + entF b0586 0.73 +0.4 616,211 + entF b0586 0.73 -0.2 616,529 + entF b0586 0.81 +1.2 616,529 + entF b0586 0.81 +1.2 616,645 + entF b0586 0.84 -1.9 616,779 - entF b0586 0.88 +1.8 616,779 - entF b0586 0.88 +3.0 616,793 - entF b0586 0.88 -1.9 616,814 + entF b0586 0.88 -0.4 616,868 + entF b0586 0.90 +3.6 616,988 - -0.4 616,993 - +0.9 617,023 - -2.4 617,024 + +0.2 617,024 + -2.8 617,038 - +1.9 617,048 + +1.2 617,066 - +1.8 617,120 + -0.8 617,121 + +0.9 617,122 + -0.4 617,133 + -0.4 617,135 - -1.9 617,136 - +3.1 617,136 - +1.8 617,138 + -2.4 617,146 - +2.0 617,155 + +1.7 617,160 - -0.9 617,162 + +1.7 617,162 + +0.6 617,162 + +2.1 617,166 + +0.2 617,168 + -1.4 617,168 - +0.1 617,170 + +0.5 617,175 + +2.2 617,175 + -1.9 617,181 + -1.4 617,181 + +0.1 617,182 + -1.4 617,183 - -0.4 617,195 + +0.1 617,206 + -0.6 617,206 + +0.2 617,206 + -0.4 617,206 + -1.6 617,206 + +1.2 617,206 + -2.1 617,235 + -0.1 617,247 + +0.2 617,272 + -1.1 617,587 - -1.4 617,616 + fepE b0587 0.12 +1.6 617,644 - fepE b0587 0.15 -0.5 617,644 - fepE b0587 0.15 -1.9 617,644 - fepE b0587 0.15 +1.3 617,701 - fepE b0587 0.20 -0.4 617,755 - fepE b0587 0.25 -2.4 617,849 + fepE b0587 0.33 -0.1 617,893 + fepE b0587 0.37 +1.2 617,893 + fepE b0587 0.37 -2.1 617,947 - fepE b0587 0.41 -0.6 617,985 - fepE b0587 0.45 +2.0 617,985 - fepE b0587 0.45 -1.6 617,986 - fepE b0587 0.45 -0.6 618,013 + fepE b0587 0.47 -1.7 618,013 + fepE b0587 0.47 +0.5 618,018 + fepE b0587 0.48 -1.1 618,018 + fepE b0587 0.48 -1.1 618,029 - fepE b0587 0.49 -0.3 618,035 + fepE b0587 0.49 -0.4 618,035 + fepE b0587 0.49 +0.2 618,035 + fepE b0587 0.49 -0.8 618,045 + fepE b0587 0.50 -0.8 618,045 + fepE b0587 0.50 -0.2 618,053 - fepE b0587 0.51 -2.2 618,071 + fepE b0587 0.52 -0.7 618,082 + fepE b0587 0.53 +1.2 618,104 + fepE b0587 0.55 -1.4 618,104 + fepE b0587 0.55 +1.6 618,114 + fepE b0587 0.56 -0.9 618,120 - fepE b0587 0.57 -2.2 618,151 - fepE b0587 0.59 -0.9 618,151 - fepE b0587 0.59 +1.2 618,190 + fepE b0587 0.63 +3.7 618,250 - fepE b0587 0.68 -0.8
Or see this region's nucleotide sequence