Strain Fitness in Escherichia coli ECOR27 around NOLOHH_18245

Experiment: Bas09

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntynfL and mlc are separated by 134 nucleotidesmlc and bioD are separated by 124 nucleotidesbioD and clcB overlap by 48 nucleotides NOLOHH_18240: ynfL - Uncharacterized HTH-type transcriptional regulator YnfL, at 3,583,449 to 3,584,342 ynfL NOLOHH_18245: mlc - DNA-binding transcriptional repressor Mlc, at 3,584,477 to 3,585,697 mlc NOLOHH_18250: bioD - dethiobiotin synthase, at 3,585,822 to 3,586,517 bioD NOLOHH_18255: clcB - voltage-gated ClC-type chloride channel ClcB, at 3,586,470 to 3,587,726 clcB Position (kb) 3584 3585 3586Strain fitness (log2 ratio) -1 0 1at 3583.532 kb on + strandat 3583.673 kb on + strand, within ynfLat 3584.065 kb on - strand, within ynfLat 3584.538 kb on + strandat 3584.967 kb on + strand, within mlcat 3584.994 kb on + strand, within mlcat 3585.180 kb on + strand, within mlcat 3585.345 kb on + strand, within mlcat 3585.792 kb on + strandat 3586.461 kb on + strandat 3586.461 kb on + strandat 3586.461 kb on + strandat 3586.597 kb on - strand, within clcBat 3586.677 kb on - strand, within clcB

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction Bas09
remove
3,583,532 + -1.3
3,583,673 + ynfL NOLOHH_18240 0.25 +0.5
3,584,065 - ynfL NOLOHH_18240 0.69 -0.7
3,584,538 + +0.3
3,584,967 + mlc NOLOHH_18245 0.40 +1.3
3,584,994 + mlc NOLOHH_18245 0.42 +0.3
3,585,180 + mlc NOLOHH_18245 0.58 -0.7
3,585,345 + mlc NOLOHH_18245 0.71 -1.3
3,585,792 + +0.3
3,586,461 + +1.0
3,586,461 + +1.3
3,586,461 + -1.7
3,586,597 - clcB NOLOHH_18255 0.10 -0.7
3,586,677 - clcB NOLOHH_18255 0.16 +0.3

Or see this region's nucleotide sequence