Experiment: BHIS_CaCl2 no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 2)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt EFB2_00384 and EFB2_00385 are separated by 56 nucleotides EFB2_00385 and EFB2_00386 are separated by 191 nucleotides
EFB2_00384: EFB2_00384 - Low-affinity gluconate transporter, at 397,127 to 398,467
_00384
EFB2_00385: EFB2_00385 - hypothetical protein, at 398,524 to 399,117
_00385
EFB2_00386: EFB2_00386 - Aspartate-semialdehyde dehydrogenase, at 399,309 to 400,412
_00386
Position (kb) 398
399
400 Strain fitness (log2 ratio) -4
-3
-2
-1
0
1
2
3 at 397.557 kb on + strand, within EFB2_00384 at 397.558 kb on - strand, within EFB2_00384 at 397.558 kb on - strand, within EFB2_00384 at 397.566 kb on + strand, within EFB2_00384 at 397.566 kb on + strand, within EFB2_00384 at 397.567 kb on - strand, within EFB2_00384 at 397.699 kb on + strand, within EFB2_00384 at 397.699 kb on + strand, within EFB2_00384 at 397.700 kb on - strand, within EFB2_00384 at 397.700 kb on - strand, within EFB2_00384 at 397.736 kb on + strand, within EFB2_00384 at 397.750 kb on + strand, within EFB2_00384 at 397.750 kb on + strand, within EFB2_00384 at 397.751 kb on - strand, within EFB2_00384 at 397.751 kb on - strand, within EFB2_00384 at 397.751 kb on - strand, within EFB2_00384 at 397.751 kb on - strand, within EFB2_00384 at 397.751 kb on - strand, within EFB2_00384 at 397.888 kb on + strand, within EFB2_00384 at 397.895 kb on + strand, within EFB2_00384 at 397.896 kb on - strand, within EFB2_00384 at 397.896 kb on - strand, within EFB2_00384 at 397.961 kb on + strand, within EFB2_00384 at 397.961 kb on + strand, within EFB2_00384 at 397.962 kb on - strand, within EFB2_00384 at 397.985 kb on - strand, within EFB2_00384 at 398.258 kb on + strand, within EFB2_00384 at 398.258 kb on + strand, within EFB2_00384 at 398.258 kb on + strand, within EFB2_00384 at 398.258 kb on + strand, within EFB2_00384 at 398.259 kb on - strand, within EFB2_00384 at 398.259 kb on - strand, within EFB2_00384 at 398.259 kb on - strand, within EFB2_00384 at 398.259 kb on - strand, within EFB2_00384 at 398.259 kb on - strand, within EFB2_00384 at 398.293 kb on + strand, within EFB2_00384 at 398.294 kb on - strand, within EFB2_00384 at 398.359 kb on + strand at 398.359 kb on + strand at 398.386 kb on + strand at 398.387 kb on - strand at 398.387 kb on - strand at 398.465 kb on + strand at 398.465 kb on + strand at 398.465 kb on + strand at 398.465 kb on + strand at 398.465 kb on + strand at 398.465 kb on + strand at 398.465 kb on + strand at 398.466 kb on - strand at 398.466 kb on - strand at 398.466 kb on - strand at 398.466 kb on - strand at 398.466 kb on - strand at 398.466 kb on - strand at 398.466 kb on - strand at 398.482 kb on + strand at 398.482 kb on + strand at 398.482 kb on + strand at 398.483 kb on - strand at 398.483 kb on - strand at 398.638 kb on + strand, within EFB2_00385 at 398.638 kb on + strand, within EFB2_00385 at 398.639 kb on - strand, within EFB2_00385 at 398.656 kb on + strand, within EFB2_00385 at 398.656 kb on + strand, within EFB2_00385 at 398.760 kb on + strand, within EFB2_00385 at 398.760 kb on + strand, within EFB2_00385 at 398.760 kb on + strand, within EFB2_00385 at 398.760 kb on + strand, within EFB2_00385 at 398.761 kb on - strand, within EFB2_00385 at 398.799 kb on + strand, within EFB2_00385 at 398.799 kb on + strand, within EFB2_00385 at 398.799 kb on + strand, within EFB2_00385 at 398.799 kb on + strand, within EFB2_00385 at 398.799 kb on + strand, within EFB2_00385 at 398.800 kb on - strand, within EFB2_00385 at 398.800 kb on - strand, within EFB2_00385 at 398.800 kb on - strand, within EFB2_00385 at 398.800 kb on - strand, within EFB2_00385 at 398.800 kb on - strand, within EFB2_00385 at 398.800 kb on - strand, within EFB2_00385 at 398.800 kb on - strand, within EFB2_00385 at 398.800 kb on - strand, within EFB2_00385 at 398.800 kb on - strand, within EFB2_00385 at 398.800 kb on - strand, within EFB2_00385 at 398.832 kb on + strand, within EFB2_00385 at 398.832 kb on + strand, within EFB2_00385 at 398.832 kb on + strand, within EFB2_00385 at 398.833 kb on - strand, within EFB2_00385 at 398.833 kb on - strand, within EFB2_00385 at 398.833 kb on - strand, within EFB2_00385 at 398.833 kb on - strand, within EFB2_00385 at 398.833 kb on - strand, within EFB2_00385 at 398.833 kb on - strand, within EFB2_00385 at 398.833 kb on - strand, within EFB2_00385 at 398.833 kb on - strand, within EFB2_00385 at 398.862 kb on + strand, within EFB2_00385 at 398.862 kb on + strand, within EFB2_00385 at 398.862 kb on + strand, within EFB2_00385 at 398.863 kb on - strand, within EFB2_00385 at 398.863 kb on - strand, within EFB2_00385 at 398.863 kb on - strand, within EFB2_00385 at 398.863 kb on - strand, within EFB2_00385 at 398.863 kb on - strand, within EFB2_00385 at 398.863 kb on - strand, within EFB2_00385 at 398.863 kb on - strand, within EFB2_00385 at 398.863 kb on - strand, within EFB2_00385 at 398.922 kb on + strand, within EFB2_00385 at 398.982 kb on + strand, within EFB2_00385 at 398.982 kb on + strand, within EFB2_00385 at 398.982 kb on + strand, within EFB2_00385 at 398.982 kb on + strand, within EFB2_00385 at 398.982 kb on + strand, within EFB2_00385 at 398.982 kb on + strand, within EFB2_00385 at 398.982 kb on + strand, within EFB2_00385 at 398.982 kb on + strand, within EFB2_00385 at 398.983 kb on - strand, within EFB2_00385 at 398.983 kb on - strand, within EFB2_00385 at 398.983 kb on - strand, within EFB2_00385 at 398.983 kb on - strand, within EFB2_00385 at 398.983 kb on - strand, within EFB2_00385 at 398.983 kb on - strand, within EFB2_00385 at 398.983 kb on - strand, within EFB2_00385 at 398.983 kb on - strand, within EFB2_00385 at 398.983 kb on - strand, within EFB2_00385 at 398.983 kb on - strand, within EFB2_00385 at 398.983 kb on - strand, within EFB2_00385 at 398.983 kb on - strand, within EFB2_00385 at 398.983 kb on - strand, within EFB2_00385 at 399.027 kb on + strand, within EFB2_00385 at 399.027 kb on + strand, within EFB2_00385 at 399.027 kb on + strand, within EFB2_00385 at 399.027 kb on + strand, within EFB2_00385 at 399.027 kb on + strand, within EFB2_00385 at 399.027 kb on + strand, within EFB2_00385 at 399.027 kb on + strand, within EFB2_00385 at 399.027 kb on + strand, within EFB2_00385 at 399.027 kb on + strand, within EFB2_00385 at 399.028 kb on - strand, within EFB2_00385 at 399.028 kb on - strand, within EFB2_00385 at 399.028 kb on - strand, within EFB2_00385 at 399.028 kb on - strand, within EFB2_00385 at 399.028 kb on - strand, within EFB2_00385 at 399.028 kb on - strand, within EFB2_00385 at 399.028 kb on - strand, within EFB2_00385 at 399.028 kb on - strand, within EFB2_00385 at 399.028 kb on - strand, within EFB2_00385 at 399.028 kb on - strand, within EFB2_00385 at 399.028 kb on - strand, within EFB2_00385 at 399.028 kb on - strand, within EFB2_00385 at 399.028 kb on - strand, within EFB2_00385 at 399.051 kb on + strand, within EFB2_00385 at 399.051 kb on + strand, within EFB2_00385 at 399.051 kb on + strand, within EFB2_00385 at 399.052 kb on - strand, within EFB2_00385 at 399.052 kb on - strand, within EFB2_00385 at 399.052 kb on - strand, within EFB2_00385 at 399.056 kb on - strand, within EFB2_00385 at 399.056 kb on - strand, within EFB2_00385 at 399.088 kb on + strand at 399.088 kb on + strand at 399.117 kb on + strand at 399.117 kb on + strand at 399.118 kb on - strand at 399.134 kb on + strand at 399.134 kb on + strand at 399.134 kb on + strand at 399.134 kb on + strand at 399.134 kb on + strand at 399.134 kb on + strand at 399.135 kb on - strand at 399.135 kb on - strand at 399.160 kb on - strand at 399.172 kb on + strand at 399.172 kb on + strand at 399.172 kb on + strand at 399.172 kb on + strand at 399.172 kb on + strand at 399.172 kb on + strand at 399.173 kb on - strand at 399.173 kb on - strand at 399.173 kb on - strand at 399.182 kb on + strand at 399.182 kb on + strand at 399.198 kb on - strand at 399.208 kb on - strand at 399.208 kb on - strand at 399.208 kb on - strand at 399.238 kb on + strand at 399.238 kb on + strand at 399.238 kb on + strand at 399.238 kb on + strand at 399.275 kb on + strand at 399.275 kb on + strand at 399.275 kb on + strand at 399.275 kb on + strand at 399.275 kb on + strand at 399.275 kb on + strand at 399.275 kb on + strand at 399.275 kb on + strand at 399.275 kb on + strand at 399.275 kb on + strand at 399.275 kb on + strand at 399.275 kb on + strand at 399.275 kb on + strand at 399.275 kb on + strand at 399.275 kb on + strand at 399.275 kb on + strand at 399.275 kb on + strand at 399.277 kb on + strand at 399.277 kb on + strand at 399.277 kb on + strand at 399.277 kb on + strand at 399.277 kb on + strand at 399.277 kb on + strand at 399.277 kb on + strand at 399.277 kb on + strand at 399.277 kb on + strand at 399.277 kb on + strand at 399.277 kb on + strand at 399.278 kb on - strand at 399.278 kb on - strand at 399.278 kb on - strand at 399.278 kb on - strand at 399.278 kb on - strand at 399.278 kb on - strand at 399.278 kb on - strand at 399.278 kb on - strand at 399.278 kb on - strand at 399.278 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction BHIS_CaCl2 no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 2) remove 397,557 + EFB2_00384 0.32 -0.6 397,558 - EFB2_00384 0.32 -1.9 397,558 - EFB2_00384 0.32 +2.1 397,566 + EFB2_00384 0.33 +0.9 397,566 + EFB2_00384 0.33 +1.7 397,567 - EFB2_00384 0.33 +1.5 397,699 + EFB2_00384 0.43 +1.1 397,699 + EFB2_00384 0.43 -0.0 397,700 - EFB2_00384 0.43 -2.8 397,700 - EFB2_00384 0.43 -1.0 397,736 + EFB2_00384 0.45 +2.8 397,750 + EFB2_00384 0.46 +2.2 397,750 + EFB2_00384 0.46 +1.2 397,751 - EFB2_00384 0.47 -1.3 397,751 - EFB2_00384 0.47 -0.9 397,751 - EFB2_00384 0.47 -4.2 397,751 - EFB2_00384 0.47 +0.2 397,751 - EFB2_00384 0.47 +0.5 397,888 + EFB2_00384 0.57 +1.2 397,895 + EFB2_00384 0.57 +1.0 397,896 - EFB2_00384 0.57 +1.1 397,896 - EFB2_00384 0.57 +0.7 397,961 + EFB2_00384 0.62 +0.8 397,961 + EFB2_00384 0.62 +1.4 397,962 - EFB2_00384 0.62 +0.6 397,985 - EFB2_00384 0.64 +0.6 398,258 + EFB2_00384 0.84 +0.2 398,258 + EFB2_00384 0.84 -1.8 398,258 + EFB2_00384 0.84 -0.3 398,258 + EFB2_00384 0.84 -0.3 398,259 - EFB2_00384 0.84 +0.3 398,259 - EFB2_00384 0.84 +0.2 398,259 - EFB2_00384 0.84 +0.4 398,259 - EFB2_00384 0.84 -2.1 398,259 - EFB2_00384 0.84 +0.6 398,293 + EFB2_00384 0.87 -0.4 398,294 - EFB2_00384 0.87 +1.0 398,359 + +2.4 398,359 + -0.6 398,386 + +0.9 398,387 - -2.6 398,387 - +0.3 398,465 + +1.9 398,465 + +0.6 398,465 + +1.0 398,465 + +1.8 398,465 + +0.9 398,465 + -0.2 398,465 + +0.4 398,466 - -0.7 398,466 - +0.8 398,466 - +2.3 398,466 - +0.1 398,466 - -0.3 398,466 - -2.7 398,466 - -0.2 398,482 + -0.3 398,482 + -1.9 398,482 + -1.4 398,483 - -0.4 398,483 - -0.1 398,638 + EFB2_00385 0.19 -0.7 398,638 + EFB2_00385 0.19 -0.0 398,639 - EFB2_00385 0.19 +1.3 398,656 + EFB2_00385 0.22 +1.5 398,656 + EFB2_00385 0.22 -1.9 398,760 + EFB2_00385 0.40 -1.6 398,760 + EFB2_00385 0.40 -0.9 398,760 + EFB2_00385 0.40 -0.4 398,760 + EFB2_00385 0.40 -0.4 398,761 - EFB2_00385 0.40 -0.7 398,799 + EFB2_00385 0.46 +0.0 398,799 + EFB2_00385 0.46 +0.2 398,799 + EFB2_00385 0.46 -1.1 398,799 + EFB2_00385 0.46 -1.7 398,799 + EFB2_00385 0.46 -1.0 398,800 - EFB2_00385 0.46 -1.1 398,800 - EFB2_00385 0.46 +0.1 398,800 - EFB2_00385 0.46 +0.2 398,800 - EFB2_00385 0.46 +0.3 398,800 - EFB2_00385 0.46 -1.0 398,800 - EFB2_00385 0.46 +1.0 398,800 - EFB2_00385 0.46 +0.4 398,800 - EFB2_00385 0.46 -1.1 398,800 - EFB2_00385 0.46 +0.5 398,800 - EFB2_00385 0.46 -0.8 398,832 + EFB2_00385 0.52 -2.0 398,832 + EFB2_00385 0.52 -0.4 398,832 + EFB2_00385 0.52 -0.4 398,833 - EFB2_00385 0.52 -1.8 398,833 - EFB2_00385 0.52 +0.5 398,833 - EFB2_00385 0.52 +0.4 398,833 - EFB2_00385 0.52 +0.2 398,833 - EFB2_00385 0.52 +0.2 398,833 - EFB2_00385 0.52 +0.9 398,833 - EFB2_00385 0.52 -0.7 398,833 - EFB2_00385 0.52 -1.0 398,862 + EFB2_00385 0.57 +0.1 398,862 + EFB2_00385 0.57 +1.2 398,862 + EFB2_00385 0.57 +1.5 398,863 - EFB2_00385 0.57 -1.6 398,863 - EFB2_00385 0.57 -0.5 398,863 - EFB2_00385 0.57 -0.6 398,863 - EFB2_00385 0.57 +0.4 398,863 - EFB2_00385 0.57 +0.2 398,863 - EFB2_00385 0.57 +0.6 398,863 - EFB2_00385 0.57 +0.1 398,863 - EFB2_00385 0.57 -3.3 398,922 + EFB2_00385 0.67 +0.2 398,982 + EFB2_00385 0.77 -0.1 398,982 + EFB2_00385 0.77 +0.9 398,982 + EFB2_00385 0.77 +0.5 398,982 + EFB2_00385 0.77 +0.2 398,982 + EFB2_00385 0.77 +1.7 398,982 + EFB2_00385 0.77 -0.0 398,982 + EFB2_00385 0.77 -1.1 398,982 + EFB2_00385 0.77 +2.6 398,983 - EFB2_00385 0.77 +0.1 398,983 - EFB2_00385 0.77 +0.2 398,983 - EFB2_00385 0.77 +0.4 398,983 - EFB2_00385 0.77 +0.9 398,983 - EFB2_00385 0.77 -2.7 398,983 - EFB2_00385 0.77 -0.5 398,983 - EFB2_00385 0.77 +0.8 398,983 - EFB2_00385 0.77 +0.8 398,983 - EFB2_00385 0.77 +0.7 398,983 - EFB2_00385 0.77 +0.1 398,983 - EFB2_00385 0.77 -0.2 398,983 - EFB2_00385 0.77 -1.0 398,983 - EFB2_00385 0.77 +0.2 399,027 + EFB2_00385 0.85 -1.8 399,027 + EFB2_00385 0.85 +0.4 399,027 + EFB2_00385 0.85 +0.7 399,027 + EFB2_00385 0.85 +0.0 399,027 + EFB2_00385 0.85 -1.8 399,027 + EFB2_00385 0.85 -0.7 399,027 + EFB2_00385 0.85 -1.6 399,027 + EFB2_00385 0.85 -0.3 399,027 + EFB2_00385 0.85 +0.5 399,028 - EFB2_00385 0.85 +0.6 399,028 - EFB2_00385 0.85 +1.0 399,028 - EFB2_00385 0.85 +0.3 399,028 - EFB2_00385 0.85 +0.7 399,028 - EFB2_00385 0.85 +0.5 399,028 - EFB2_00385 0.85 -0.9 399,028 - EFB2_00385 0.85 +0.7 399,028 - EFB2_00385 0.85 -1.4 399,028 - EFB2_00385 0.85 +0.2 399,028 - EFB2_00385 0.85 +1.2 399,028 - EFB2_00385 0.85 +0.6 399,028 - EFB2_00385 0.85 -1.0 399,028 - EFB2_00385 0.85 -0.8 399,051 + EFB2_00385 0.89 +0.1 399,051 + EFB2_00385 0.89 -0.8 399,051 + EFB2_00385 0.89 +0.1 399,052 - EFB2_00385 0.89 -0.7 399,052 - EFB2_00385 0.89 -0.8 399,052 - EFB2_00385 0.89 -0.2 399,056 - EFB2_00385 0.90 -1.0 399,056 - EFB2_00385 0.90 -2.3 399,088 + -1.5 399,088 + +1.8 399,117 + +0.1 399,117 + -1.2 399,118 - +0.5 399,134 + -0.7 399,134 + +1.5 399,134 + -2.8 399,134 + +0.4 399,134 + -0.8 399,134 + -0.3 399,135 - -3.1 399,135 - +2.1 399,160 - -1.0 399,172 + +0.4 399,172 + -1.4 399,172 + -0.5 399,172 + +2.2 399,172 + -0.9 399,172 + +1.5 399,173 - +0.3 399,173 - -1.0 399,173 - -0.9 399,182 + -0.8 399,182 + -0.7 399,198 - +0.3 399,208 - -0.8 399,208 - +0.9 399,208 - -2.1 399,238 + -1.8 399,238 + +0.4 399,238 + +0.7 399,238 + +1.9 399,275 + +2.4 399,275 + +0.5 399,275 + -0.6 399,275 + -3.2 399,275 + -0.3 399,275 + -1.3 399,275 + +0.3 399,275 + -0.2 399,275 + +1.2 399,275 + -2.0 399,275 + -0.7 399,275 + +1.2 399,275 + +0.4 399,275 + +0.9 399,275 + +0.1 399,275 + +0.3 399,275 + +0.1 399,277 + +0.5 399,277 + +0.0 399,277 + +1.3 399,277 + -0.0 399,277 + -0.7 399,277 + -0.5 399,277 + -2.4 399,277 + +1.4 399,277 + -0.4 399,277 + +1.2 399,277 + -1.8 399,278 - +0.3 399,278 - +0.5 399,278 - -2.2 399,278 - -0.8 399,278 - +1.1 399,278 - +1.3 399,278 - +1.8 399,278 - -0.2 399,278 - -2.2 399,278 - -1.2
Or see this region's nucleotide sequence