Experiment: phage mixed community; hk phage cocktail 1 MOI; stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 1)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt EFB2_00775 and EFB2_00776 are separated by 24 nucleotides EFB2_00776 and EFB2_00777 overlap by 1 nucleotides EFB2_00777 and EFB2_00778 are separated by 28 nucleotides
EFB2_00775: EFB2_00775 - hypothetical protein, at 789,236 to 789,658
_00775
EFB2_00776: EFB2_00776 - 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, at 789,683 to 790,510
_00776
EFB2_00777: EFB2_00777 - hypothetical protein, at 790,510 to 791,091
_00777
EFB2_00778: EFB2_00778 - DNA topoisomerase 4 subunit B, at 791,120 to 793,012
_00778
Position (kb) 790
791
792 Strain fitness (log2 ratio) -4
-3
-2
-1
0
1
2
3 at 789.540 kb on - strand, within EFB2_00775 at 789.545 kb on + strand, within EFB2_00775 at 789.545 kb on + strand, within EFB2_00775 at 789.545 kb on + strand, within EFB2_00775 at 789.546 kb on - strand, within EFB2_00775 at 789.553 kb on + strand, within EFB2_00775 at 789.554 kb on - strand, within EFB2_00775 at 789.589 kb on + strand, within EFB2_00775 at 789.617 kb on + strand at 789.653 kb on + strand at 789.653 kb on + strand at 789.653 kb on + strand at 789.654 kb on - strand at 789.654 kb on - strand at 789.654 kb on - strand at 789.654 kb on - strand at 789.656 kb on + strand at 789.657 kb on - strand at 789.657 kb on - strand at 789.671 kb on + strand at 789.671 kb on + strand at 789.671 kb on + strand at 789.671 kb on + strand at 789.671 kb on + strand at 789.672 kb on - strand at 789.672 kb on - strand at 789.672 kb on - strand at 789.736 kb on - strand at 789.743 kb on - strand at 789.789 kb on + strand, within EFB2_00776 at 789.806 kb on + strand, within EFB2_00776 at 789.807 kb on - strand, within EFB2_00776 at 789.807 kb on - strand, within EFB2_00776 at 789.807 kb on - strand, within EFB2_00776 at 789.877 kb on - strand, within EFB2_00776 at 789.902 kb on + strand, within EFB2_00776 at 789.902 kb on + strand, within EFB2_00776 at 789.902 kb on + strand, within EFB2_00776 at 789.986 kb on + strand, within EFB2_00776 at 789.986 kb on + strand, within EFB2_00776 at 789.986 kb on + strand, within EFB2_00776 at 789.986 kb on + strand, within EFB2_00776 at 789.986 kb on + strand, within EFB2_00776 at 789.986 kb on + strand, within EFB2_00776 at 789.986 kb on + strand, within EFB2_00776 at 789.987 kb on - strand, within EFB2_00776 at 789.987 kb on - strand, within EFB2_00776 at 789.987 kb on - strand, within EFB2_00776 at 789.987 kb on - strand, within EFB2_00776 at 789.987 kb on - strand, within EFB2_00776 at 789.997 kb on - strand, within EFB2_00776 at 790.009 kb on + strand, within EFB2_00776 at 790.033 kb on + strand, within EFB2_00776 at 790.034 kb on - strand, within EFB2_00776 at 790.129 kb on + strand, within EFB2_00776 at 790.129 kb on + strand, within EFB2_00776 at 790.129 kb on + strand, within EFB2_00776 at 790.130 kb on - strand, within EFB2_00776 at 790.130 kb on - strand, within EFB2_00776 at 790.156 kb on + strand, within EFB2_00776 at 790.156 kb on + strand, within EFB2_00776 at 790.156 kb on + strand, within EFB2_00776 at 790.156 kb on + strand, within EFB2_00776 at 790.156 kb on + strand, within EFB2_00776 at 790.156 kb on + strand, within EFB2_00776 at 790.156 kb on + strand, within EFB2_00776 at 790.156 kb on + strand, within EFB2_00776 at 790.156 kb on + strand, within EFB2_00776 at 790.156 kb on + strand, within EFB2_00776 at 790.156 kb on + strand, within EFB2_00776 at 790.157 kb on - strand, within EFB2_00776 at 790.157 kb on - strand, within EFB2_00776 at 790.157 kb on - strand, within EFB2_00776 at 790.157 kb on - strand, within EFB2_00776 at 790.157 kb on - strand, within EFB2_00776 at 790.185 kb on + strand, within EFB2_00776 at 790.198 kb on + strand, within EFB2_00776 at 790.198 kb on + strand, within EFB2_00776 at 790.198 kb on + strand, within EFB2_00776 at 790.198 kb on + strand, within EFB2_00776 at 790.198 kb on + strand, within EFB2_00776 at 790.198 kb on + strand, within EFB2_00776 at 790.198 kb on + strand, within EFB2_00776 at 790.198 kb on + strand, within EFB2_00776 at 790.198 kb on + strand, within EFB2_00776 at 790.198 kb on + strand, within EFB2_00776 at 790.198 kb on + strand, within EFB2_00776 at 790.198 kb on + strand, within EFB2_00776 at 790.198 kb on + strand, within EFB2_00776 at 790.198 kb on + strand, within EFB2_00776 at 790.199 kb on - strand, within EFB2_00776 at 790.199 kb on - strand, within EFB2_00776 at 790.199 kb on - strand, within EFB2_00776 at 790.199 kb on - strand, within EFB2_00776 at 790.199 kb on - strand, within EFB2_00776 at 790.199 kb on - strand, within EFB2_00776 at 790.199 kb on - strand, within EFB2_00776 at 790.199 kb on - strand, within EFB2_00776 at 790.199 kb on - strand, within EFB2_00776 at 790.199 kb on - strand, within EFB2_00776 at 790.199 kb on - strand, within EFB2_00776 at 790.199 kb on - strand, within EFB2_00776 at 790.199 kb on - strand, within EFB2_00776 at 790.199 kb on - strand, within EFB2_00776 at 790.226 kb on - strand, within EFB2_00776 at 790.274 kb on + strand, within EFB2_00776 at 790.274 kb on + strand, within EFB2_00776 at 790.274 kb on + strand, within EFB2_00776 at 790.274 kb on + strand, within EFB2_00776 at 790.274 kb on + strand, within EFB2_00776 at 790.274 kb on + strand, within EFB2_00776 at 790.274 kb on + strand, within EFB2_00776 at 790.274 kb on + strand, within EFB2_00776 at 790.275 kb on - strand, within EFB2_00776 at 790.275 kb on - strand, within EFB2_00776 at 790.275 kb on - strand, within EFB2_00776 at 790.291 kb on + strand, within EFB2_00776 at 790.291 kb on + strand, within EFB2_00776 at 790.291 kb on + strand, within EFB2_00776 at 790.291 kb on + strand, within EFB2_00776 at 790.291 kb on + strand, within EFB2_00776 at 790.291 kb on + strand, within EFB2_00776 at 790.292 kb on - strand, within EFB2_00776 at 790.292 kb on - strand, within EFB2_00776 at 790.292 kb on - strand, within EFB2_00776 at 790.363 kb on + strand, within EFB2_00776 at 790.364 kb on - strand, within EFB2_00776 at 790.378 kb on + strand, within EFB2_00776 at 790.378 kb on + strand, within EFB2_00776 at 790.378 kb on + strand, within EFB2_00776 at 790.379 kb on - strand, within EFB2_00776 at 790.384 kb on + strand, within EFB2_00776 at 790.385 kb on - strand, within EFB2_00776 at 790.385 kb on - strand, within EFB2_00776 at 790.385 kb on - strand, within EFB2_00776 at 790.414 kb on + strand, within EFB2_00776 at 790.425 kb on + strand, within EFB2_00776 at 790.425 kb on + strand, within EFB2_00776 at 790.425 kb on + strand, within EFB2_00776 at 790.425 kb on + strand, within EFB2_00776 at 790.425 kb on + strand, within EFB2_00776 at 790.425 kb on + strand, within EFB2_00776 at 790.425 kb on + strand, within EFB2_00776 at 790.425 kb on + strand, within EFB2_00776 at 790.426 kb on - strand, within EFB2_00776 at 790.426 kb on - strand, within EFB2_00776 at 790.426 kb on - strand, within EFB2_00776 at 790.426 kb on - strand, within EFB2_00776 at 790.426 kb on - strand, within EFB2_00776 at 790.426 kb on - strand, within EFB2_00776 at 790.426 kb on - strand, within EFB2_00776 at 790.426 kb on - strand, within EFB2_00776 at 790.426 kb on - strand, within EFB2_00776 at 790.426 kb on - strand, within EFB2_00776 at 790.426 kb on - strand, within EFB2_00776 at 790.505 kb on + strand at 790.505 kb on + strand at 790.506 kb on - strand at 790.506 kb on - strand at 790.506 kb on - strand at 790.506 kb on - strand at 790.506 kb on - strand at 790.515 kb on + strand at 790.515 kb on + strand at 790.515 kb on + strand at 790.515 kb on + strand at 790.516 kb on - strand at 790.516 kb on - strand at 790.516 kb on - strand at 790.516 kb on - strand at 790.525 kb on + strand at 790.526 kb on - strand at 790.526 kb on - strand at 790.526 kb on - strand at 790.529 kb on + strand at 790.529 kb on + strand at 790.529 kb on + strand at 790.529 kb on + strand at 790.530 kb on - strand at 790.530 kb on - strand at 790.530 kb on - strand at 790.701 kb on + strand, within EFB2_00777 at 790.702 kb on - strand, within EFB2_00777 at 790.726 kb on + strand, within EFB2_00777 at 790.726 kb on + strand, within EFB2_00777 at 790.726 kb on + strand, within EFB2_00777 at 790.727 kb on - strand, within EFB2_00777 at 790.727 kb on - strand, within EFB2_00777 at 790.727 kb on - strand, within EFB2_00777 at 790.729 kb on + strand, within EFB2_00777 at 790.729 kb on + strand, within EFB2_00777 at 790.729 kb on + strand, within EFB2_00777 at 790.729 kb on + strand, within EFB2_00777 at 790.729 kb on + strand, within EFB2_00777 at 790.729 kb on + strand, within EFB2_00777 at 790.729 kb on + strand, within EFB2_00777 at 790.729 kb on + strand, within EFB2_00777 at 790.729 kb on + strand, within EFB2_00777 at 790.729 kb on + strand, within EFB2_00777 at 790.730 kb on - strand, within EFB2_00777 at 790.730 kb on - strand, within EFB2_00777 at 790.730 kb on - strand, within EFB2_00777 at 790.730 kb on - strand, within EFB2_00777 at 790.730 kb on - strand, within EFB2_00777 at 790.755 kb on + strand, within EFB2_00777 at 790.755 kb on + strand, within EFB2_00777 at 790.755 kb on + strand, within EFB2_00777 at 790.755 kb on + strand, within EFB2_00777 at 790.755 kb on + strand, within EFB2_00777 at 790.755 kb on + strand, within EFB2_00777 at 790.756 kb on - strand, within EFB2_00777 at 790.756 kb on - strand, within EFB2_00777 at 790.756 kb on - strand, within EFB2_00777 at 790.756 kb on - strand, within EFB2_00777 at 790.756 kb on - strand, within EFB2_00777 at 790.813 kb on + strand, within EFB2_00777 at 790.813 kb on + strand, within EFB2_00777 at 790.813 kb on + strand, within EFB2_00777 at 790.813 kb on + strand, within EFB2_00777 at 790.813 kb on + strand, within EFB2_00777 at 790.813 kb on + strand, within EFB2_00777 at 790.814 kb on - strand, within EFB2_00777 at 790.814 kb on - strand, within EFB2_00777 at 790.837 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.852 kb on + strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.853 kb on - strand, within EFB2_00777 at 790.859 kb on + strand, within EFB2_00777 at 790.859 kb on + strand, within EFB2_00777 at 790.859 kb on + strand, within EFB2_00777 at 790.859 kb on + strand, within EFB2_00777 at 790.872 kb on + strand, within EFB2_00777 at 790.872 kb on + strand, within EFB2_00777 at 790.872 kb on + strand, within EFB2_00777 at 790.876 kb on + strand, within EFB2_00777 at 790.876 kb on + strand, within EFB2_00777 at 790.876 kb on + strand, within EFB2_00777 at 790.876 kb on + strand, within EFB2_00777 at 790.876 kb on + strand, within EFB2_00777 at 790.984 kb on + strand, within EFB2_00777 at 790.984 kb on + strand, within EFB2_00777 at 790.984 kb on + strand, within EFB2_00777 at 790.984 kb on + strand, within EFB2_00777 at 790.984 kb on + strand, within EFB2_00777 at 790.984 kb on + strand, within EFB2_00777 at 790.984 kb on + strand, within EFB2_00777 at 790.984 kb on + strand, within EFB2_00777 at 790.984 kb on + strand, within EFB2_00777 at 790.984 kb on + strand, within EFB2_00777 at 791.009 kb on + strand, within EFB2_00777 at 791.009 kb on + strand, within EFB2_00777 at 791.009 kb on + strand, within EFB2_00777 at 791.009 kb on + strand, within EFB2_00777 at 791.009 kb on + strand, within EFB2_00777 at 791.009 kb on + strand, within EFB2_00777 at 791.009 kb on + strand, within EFB2_00777 at 791.009 kb on + strand, within EFB2_00777 at 791.009 kb on + strand, within EFB2_00777 at 791.009 kb on + strand, within EFB2_00777 at 791.009 kb on + strand, within EFB2_00777 at 791.009 kb on + strand, within EFB2_00777 at 791.009 kb on + strand, within EFB2_00777 at 791.047 kb on + strand at 791.109 kb on + strand at 791.109 kb on + strand at 791.109 kb on + strand at 791.109 kb on + strand at 791.109 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction phage mixed community; hk phage cocktail 1 MOI; stool-derived community from humanized mice (condition: pre-antibiotic, MAC-deficient diet, mouse 1) remove 789,540 - EFB2_00775 0.72 -0.9 789,545 + EFB2_00775 0.73 -2.3 789,545 + EFB2_00775 0.73 -1.9 789,545 + EFB2_00775 0.73 +0.6 789,546 - EFB2_00775 0.73 +0.6 789,553 + EFB2_00775 0.75 +1.8 789,554 - EFB2_00775 0.75 +1.3 789,589 + EFB2_00775 0.83 +0.7 789,617 + +2.2 789,653 + -1.5 789,653 + -0.3 789,653 + -2.3 789,654 - -1.4 789,654 - -1.9 789,654 - -1.8 789,654 - +0.6 789,656 + -1.4 789,657 - -0.1 789,657 - -3.4 789,671 + -2.7 789,671 + -2.7 789,671 + +0.4 789,671 + +1.1 789,671 + -1.2 789,672 - -3.5 789,672 - -2.3 789,672 - -0.2 789,736 - -2.3 789,743 - -2.0 789,789 + EFB2_00776 0.13 +0.9 789,806 + EFB2_00776 0.15 -0.2 789,807 - EFB2_00776 0.15 -2.5 789,807 - EFB2_00776 0.15 -1.1 789,807 - EFB2_00776 0.15 -1.2 789,877 - EFB2_00776 0.23 -1.2 789,902 + EFB2_00776 0.26 +0.6 789,902 + EFB2_00776 0.26 -1.8 789,902 + EFB2_00776 0.26 -2.6 789,986 + EFB2_00776 0.37 -2.9 789,986 + EFB2_00776 0.37 -1.5 789,986 + EFB2_00776 0.37 -1.9 789,986 + EFB2_00776 0.37 -0.8 789,986 + EFB2_00776 0.37 -1.1 789,986 + EFB2_00776 0.37 -1.6 789,986 + EFB2_00776 0.37 -0.7 789,987 - EFB2_00776 0.37 -3.2 789,987 - EFB2_00776 0.37 -2.0 789,987 - EFB2_00776 0.37 -0.6 789,987 - EFB2_00776 0.37 -3.3 789,987 - EFB2_00776 0.37 -2.3 789,997 - EFB2_00776 0.38 +0.2 790,009 + EFB2_00776 0.39 -0.8 790,033 + EFB2_00776 0.42 +1.7 790,034 - EFB2_00776 0.42 -1.9 790,129 + EFB2_00776 0.54 +0.4 790,129 + EFB2_00776 0.54 -2.7 790,129 + EFB2_00776 0.54 -1.4 790,130 - EFB2_00776 0.54 -0.6 790,130 - EFB2_00776 0.54 +0.2 790,156 + EFB2_00776 0.57 -2.5 790,156 + EFB2_00776 0.57 +0.3 790,156 + EFB2_00776 0.57 -1.1 790,156 + EFB2_00776 0.57 -3.3 790,156 + EFB2_00776 0.57 -0.1 790,156 + EFB2_00776 0.57 +0.0 790,156 + EFB2_00776 0.57 -0.6 790,156 + EFB2_00776 0.57 -0.2 790,156 + EFB2_00776 0.57 -0.7 790,156 + EFB2_00776 0.57 -1.3 790,156 + EFB2_00776 0.57 +0.5 790,157 - EFB2_00776 0.57 -0.0 790,157 - EFB2_00776 0.57 -0.4 790,157 - EFB2_00776 0.57 -3.4 790,157 - EFB2_00776 0.57 -0.2 790,157 - EFB2_00776 0.57 -1.0 790,185 + EFB2_00776 0.61 -4.2 790,198 + EFB2_00776 0.62 -1.6 790,198 + EFB2_00776 0.62 -0.9 790,198 + EFB2_00776 0.62 -1.0 790,198 + EFB2_00776 0.62 -2.0 790,198 + EFB2_00776 0.62 -3.7 790,198 + EFB2_00776 0.62 -1.4 790,198 + EFB2_00776 0.62 -1.7 790,198 + EFB2_00776 0.62 -1.7 790,198 + EFB2_00776 0.62 -0.4 790,198 + EFB2_00776 0.62 -2.1 790,198 + EFB2_00776 0.62 -2.2 790,198 + EFB2_00776 0.62 -4.1 790,198 + EFB2_00776 0.62 -2.2 790,198 + EFB2_00776 0.62 -1.0 790,199 - EFB2_00776 0.62 +0.5 790,199 - EFB2_00776 0.62 -3.5 790,199 - EFB2_00776 0.62 +0.4 790,199 - EFB2_00776 0.62 -3.2 790,199 - EFB2_00776 0.62 -1.7 790,199 - EFB2_00776 0.62 -2.0 790,199 - EFB2_00776 0.62 -0.2 790,199 - EFB2_00776 0.62 -1.1 790,199 - EFB2_00776 0.62 -0.8 790,199 - EFB2_00776 0.62 -0.8 790,199 - EFB2_00776 0.62 -3.1 790,199 - EFB2_00776 0.62 -2.3 790,199 - EFB2_00776 0.62 +0.7 790,199 - EFB2_00776 0.62 -0.3 790,226 - EFB2_00776 0.66 -1.5 790,274 + EFB2_00776 0.71 -1.0 790,274 + EFB2_00776 0.71 -2.0 790,274 + EFB2_00776 0.71 -0.2 790,274 + EFB2_00776 0.71 -0.7 790,274 + EFB2_00776 0.71 -1.1 790,274 + EFB2_00776 0.71 -0.8 790,274 + EFB2_00776 0.71 -1.8 790,274 + EFB2_00776 0.71 -1.3 790,275 - EFB2_00776 0.71 -3.1 790,275 - EFB2_00776 0.71 -1.2 790,275 - EFB2_00776 0.71 -0.6 790,291 + EFB2_00776 0.73 -1.0 790,291 + EFB2_00776 0.73 -3.8 790,291 + EFB2_00776 0.73 -0.9 790,291 + EFB2_00776 0.73 -2.9 790,291 + EFB2_00776 0.73 -1.1 790,291 + EFB2_00776 0.73 -2.1 790,292 - EFB2_00776 0.74 -2.3 790,292 - 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Or see this region's nucleotide sequence