Experiment: BHIS no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, standard diet, mouse 1)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt EFB2_00855 and EFB2_00856 overlap by 4 nucleotides EFB2_00856 and EFB2_00857 are separated by 11 nucleotides EFB2_00857 and EFB2_00858 are separated by 15 nucleotides
EFB2_00855: EFB2_00855 - Polysialic acid transport protein KpsM, at 877,597 to 878,373
_00855
EFB2_00856: EFB2_00856 - Polysialic acid transport ATP-binding protein KpsT, at 878,370 to 879,041
_00856
EFB2_00857: EFB2_00857 - Glycerol-3-phosphate cytidylyltransferase, at 879,053 to 879,448
_00857
EFB2_00858: EFB2_00858 - hypothetical protein, at 879,464 to 880,699
_00858
Position (kb) 878
879
880 Strain fitness (log2 ratio) -4
-3
-2
-1
0
1
2
3 at 877.383 kb on + strand at 877.384 kb on - strand at 877.384 kb on - strand at 877.384 kb on - strand at 877.428 kb on - strand at 877.428 kb on - strand at 877.471 kb on + strand at 877.474 kb on + strand at 877.517 kb on + strand at 877.517 kb on + strand at 877.518 kb on - strand at 877.525 kb on - strand at 877.525 kb on - strand at 877.535 kb on + strand at 877.535 kb on + strand at 877.536 kb on - strand at 877.536 kb on - strand at 877.542 kb on - strand at 877.542 kb on - strand at 877.542 kb on - strand at 877.567 kb on + strand at 877.567 kb on + strand at 877.568 kb on - strand at 877.580 kb on + strand at 877.581 kb on - strand at 877.581 kb on - strand at 877.581 kb on - strand at 877.581 kb on - strand at 877.635 kb on - strand at 877.644 kb on - strand at 877.644 kb on - strand at 877.644 kb on - strand at 877.658 kb on + strand at 877.658 kb on + strand at 877.659 kb on - strand at 877.691 kb on - strand, within EFB2_00855 at 877.691 kb on - strand, within EFB2_00855 at 877.755 kb on + strand, within EFB2_00855 at 877.755 kb on + strand, within EFB2_00855 at 877.756 kb on - strand, within EFB2_00855 at 877.756 kb on - strand, within EFB2_00855 at 877.797 kb on - strand, within EFB2_00855 at 877.801 kb on - strand, within EFB2_00855 at 877.801 kb on - strand, within EFB2_00855 at 877.822 kb on - strand, within EFB2_00855 at 877.828 kb on - strand, within EFB2_00855 at 877.833 kb on + strand, within EFB2_00855 at 877.850 kb on + strand, within EFB2_00855 at 877.850 kb on + strand, within EFB2_00855 at 877.850 kb on + strand, within EFB2_00855 at 877.850 kb on + strand, within EFB2_00855 at 877.851 kb on - strand, within EFB2_00855 at 877.851 kb on - strand, within EFB2_00855 at 877.945 kb on + strand, within EFB2_00855 at 877.945 kb on + strand, within EFB2_00855 at 877.946 kb on - strand, within EFB2_00855 at 877.946 kb on - strand, within EFB2_00855 at 877.957 kb on + strand, within EFB2_00855 at 877.957 kb on + strand, within EFB2_00855 at 877.957 kb on + strand, within EFB2_00855 at 877.958 kb on - strand, within EFB2_00855 at 877.958 kb on - strand, within EFB2_00855 at 877.959 kb on + strand, within EFB2_00855 at 877.959 kb on + strand, within EFB2_00855 at 877.959 kb on + strand, within EFB2_00855 at 877.959 kb on + strand, within EFB2_00855 at 877.960 kb on - strand, within EFB2_00855 at 877.960 kb on - strand, within EFB2_00855 at 877.960 kb on - strand, within EFB2_00855 at 877.961 kb on + strand, within EFB2_00855 at 877.961 kb on + strand, within EFB2_00855 at 877.961 kb on + strand, within EFB2_00855 at 877.962 kb on - strand, within EFB2_00855 at 877.962 kb on - strand, within EFB2_00855 at 877.962 kb on - strand, within EFB2_00855 at 877.962 kb on - strand, within EFB2_00855 at 877.962 kb on - strand, within EFB2_00855 at 877.968 kb on + strand, within EFB2_00855 at 877.969 kb on - strand, within EFB2_00855 at 877.974 kb on + strand, within EFB2_00855 at 877.974 kb on + strand, within EFB2_00855 at 877.975 kb on - strand, within EFB2_00855 at 878.072 kb on + strand, within EFB2_00855 at 878.073 kb on - strand, within EFB2_00855 at 878.075 kb on + strand, within EFB2_00855 at 878.075 kb on + strand, within EFB2_00855 at 878.076 kb on - strand, within EFB2_00855 at 878.091 kb on + strand, within EFB2_00855 at 878.126 kb on + strand, within EFB2_00855 at 878.192 kb on - strand, within EFB2_00855 at 878.192 kb on - strand, within EFB2_00855 at 878.200 kb on + strand, within EFB2_00855 at 878.200 kb on + strand, within EFB2_00855 at 878.200 kb on + strand, within EFB2_00855 at 878.200 kb on + strand, within EFB2_00855 at 878.200 kb on + strand, within EFB2_00855 at 878.200 kb on + strand, within EFB2_00855 at 878.200 kb on + strand, within EFB2_00855 at 878.200 kb on + strand, within EFB2_00855 at 878.201 kb on - strand, within EFB2_00855 at 878.201 kb on - strand, within EFB2_00855 at 878.201 kb on - strand, within EFB2_00855 at 878.201 kb on - strand, within EFB2_00855 at 878.201 kb on - strand, within EFB2_00855 at 878.201 kb on - strand, within EFB2_00855 at 878.204 kb on + strand, within EFB2_00855 at 878.204 kb on + strand, within EFB2_00855 at 878.204 kb on + strand, within EFB2_00855 at 878.204 kb on + strand, within EFB2_00855 at 878.204 kb on + strand, within EFB2_00855 at 878.204 kb on + strand, within EFB2_00855 at 878.205 kb on - strand, within EFB2_00855 at 878.205 kb on - strand, within EFB2_00855 at 878.219 kb on + strand, within EFB2_00855 at 878.231 kb on + strand, within EFB2_00855 at 878.231 kb on + strand, within EFB2_00855 at 878.231 kb on + strand, within EFB2_00855 at 878.231 kb on + strand, within EFB2_00855 at 878.232 kb on - strand, within EFB2_00855 at 878.232 kb on - strand, within EFB2_00855 at 878.237 kb on + strand, within EFB2_00855 at 878.238 kb on - strand, within EFB2_00855 at 878.238 kb on - strand, within EFB2_00855 at 878.253 kb on + strand, within EFB2_00855 at 878.253 kb on + strand, within EFB2_00855 at 878.253 kb on + strand, within EFB2_00855 at 878.254 kb on - strand, within EFB2_00855 at 878.254 kb on - strand, within EFB2_00855 at 878.263 kb on + strand, within EFB2_00855 at 878.263 kb on + strand, within EFB2_00855 at 878.263 kb on + strand, within EFB2_00855 at 878.263 kb on + strand, within EFB2_00855 at 878.263 kb on + strand, within EFB2_00855 at 878.263 kb on + strand, within EFB2_00855 at 878.263 kb on + strand, within EFB2_00855 at 878.263 kb on + strand, within EFB2_00855 at 878.264 kb on - strand, within EFB2_00855 at 878.264 kb on - strand, within EFB2_00855 at 878.264 kb on - strand, within EFB2_00855 at 878.266 kb on - strand, within EFB2_00855 at 878.266 kb on - strand, within EFB2_00855 at 878.290 kb on + strand, within EFB2_00855 at 878.290 kb on + strand, within EFB2_00855 at 878.290 kb on + strand, within EFB2_00855 at 878.290 kb on + strand, within EFB2_00855 at 878.338 kb on + strand at 878.338 kb on + strand at 878.339 kb on - strand at 878.339 kb on - strand at 878.375 kb on + strand at 878.375 kb on + strand at 878.375 kb on + strand at 878.375 kb on + strand at 878.376 kb on - strand at 878.376 kb on - strand at 878.376 kb on - strand at 878.401 kb on - strand at 878.424 kb on + strand at 878.424 kb on + strand at 878.425 kb on - strand at 878.425 kb on - strand at 878.425 kb on - strand at 878.425 kb on - strand at 878.425 kb on - strand at 878.440 kb on + strand, within EFB2_00856 at 878.478 kb on - strand, within EFB2_00856 at 878.499 kb on - strand, within EFB2_00856 at 878.562 kb on - strand, within EFB2_00856 at 878.572 kb on + strand, within EFB2_00856 at 878.573 kb on - strand, within EFB2_00856 at 878.650 kb on + strand, within EFB2_00856 at 878.650 kb on + strand, within EFB2_00856 at 878.653 kb on - strand, within EFB2_00856 at 878.715 kb on - strand, within EFB2_00856 at 878.715 kb on - strand, within EFB2_00856 at 878.718 kb on + strand, within EFB2_00856 at 878.719 kb on - strand, within EFB2_00856 at 878.754 kb on - strand, within EFB2_00856 at 878.779 kb on + strand, within EFB2_00856 at 878.793 kb on - strand, within EFB2_00856 at 878.802 kb on + strand, within EFB2_00856 at 878.805 kb on + strand, within EFB2_00856 at 878.805 kb on + strand, within EFB2_00856 at 878.806 kb on - strand, within EFB2_00856 at 878.806 kb on - strand, within EFB2_00856 at 878.806 kb on - strand, within EFB2_00856 at 878.807 kb on + strand, within EFB2_00856 at 878.808 kb on - strand, within EFB2_00856 at 878.821 kb on + strand, within EFB2_00856 at 878.951 kb on - strand, within EFB2_00856 at 878.954 kb on + strand, within EFB2_00856 at 879.088 kb on - strand at 879.096 kb on + strand, within EFB2_00857 at 879.097 kb on - strand, within EFB2_00857 at 879.105 kb on + strand, within EFB2_00857 at 879.110 kb on - strand, within EFB2_00857 at 879.110 kb on - strand, within EFB2_00857 at 879.295 kb on + strand, within EFB2_00857 at 879.316 kb on + strand, within EFB2_00857 at 879.370 kb on - strand, within EFB2_00857 at 879.421 kb on - strand at 879.537 kb on + strand at 879.541 kb on - strand at 879.541 kb on - strand at 879.641 kb on + strand, within EFB2_00858 at 879.677 kb on + strand, within EFB2_00858 at 879.677 kb on + strand, within EFB2_00858 at 879.678 kb on - strand, within EFB2_00858 at 879.678 kb on - strand, within EFB2_00858 at 879.679 kb on + strand, within EFB2_00858 at 879.679 kb on + strand, within EFB2_00858 at 879.679 kb on + strand, within EFB2_00858 at 879.679 kb on + strand, within EFB2_00858 at 879.680 kb on - strand, within EFB2_00858 at 879.680 kb on - strand, within EFB2_00858 at 879.681 kb on + strand, within EFB2_00858 at 879.682 kb on - strand, within EFB2_00858 at 879.718 kb on - strand, within EFB2_00858 at 879.731 kb on - strand, within EFB2_00858 at 879.740 kb on + strand, within EFB2_00858 at 879.798 kb on + strand, within EFB2_00858 at 879.802 kb on + strand, within EFB2_00858 at 879.802 kb on + strand, within EFB2_00858 at 879.889 kb on - strand, within EFB2_00858 at 879.917 kb on + strand, within EFB2_00858 at 879.925 kb on + strand, within EFB2_00858 at 879.928 kb on - strand, within EFB2_00858 at 879.942 kb on - strand, within EFB2_00858 at 879.964 kb on - strand, within EFB2_00858 at 879.987 kb on + strand, within EFB2_00858 at 879.987 kb on + strand, within EFB2_00858 at 879.987 kb on + strand, within EFB2_00858 at 879.987 kb on + strand, within EFB2_00858 at 879.987 kb on + strand, within EFB2_00858 at 879.988 kb on - strand, within EFB2_00858 at 879.989 kb on + strand, within EFB2_00858 at 879.989 kb on + strand, within EFB2_00858 at 879.990 kb on - strand, within EFB2_00858
Per-strain Table
Position Strand Gene LocusTag Fraction BHIS no phage control with stool-derived community from humanized mice (condition: pre-antibiotic, standard diet, mouse 1) remove 877,383 + -0.5 877,384 - +0.3 877,384 - +0.9 877,384 - -0.3 877,428 - +0.8 877,428 - -1.0 877,471 + -2.2 877,474 + -0.2 877,517 + +0.3 877,517 + -1.1 877,518 - +1.3 877,525 - -2.2 877,525 - +0.1 877,535 + -0.4 877,535 + -1.6 877,536 - +0.2 877,536 - -2.7 877,542 - -0.2 877,542 - -0.6 877,542 - +0.6 877,567 + -1.5 877,567 + -1.0 877,568 - -0.4 877,580 + +1.7 877,581 - +0.3 877,581 - -1.7 877,581 - -0.8 877,581 - -1.7 877,635 - -2.0 877,644 - -2.0 877,644 - -1.3 877,644 - +0.0 877,658 + -3.2 877,658 + -0.3 877,659 - -1.1 877,691 - EFB2_00855 0.12 -1.3 877,691 - EFB2_00855 0.12 +0.7 877,755 + EFB2_00855 0.20 +1.8 877,755 + EFB2_00855 0.20 -0.5 877,756 - EFB2_00855 0.20 -0.5 877,756 - EFB2_00855 0.20 -1.1 877,797 - EFB2_00855 0.26 +1.0 877,801 - EFB2_00855 0.26 +0.5 877,801 - EFB2_00855 0.26 -0.3 877,822 - EFB2_00855 0.29 +0.3 877,828 - EFB2_00855 0.30 +1.1 877,833 + EFB2_00855 0.30 +0.7 877,850 + EFB2_00855 0.33 +1.9 877,850 + EFB2_00855 0.33 -0.8 877,850 + EFB2_00855 0.33 +1.0 877,850 + EFB2_00855 0.33 -0.8 877,851 - EFB2_00855 0.33 -2.1 877,851 - EFB2_00855 0.33 -0.1 877,945 + EFB2_00855 0.45 +2.0 877,945 + EFB2_00855 0.45 -2.8 877,946 - EFB2_00855 0.45 -0.6 877,946 - EFB2_00855 0.45 +1.1 877,957 + EFB2_00855 0.46 -3.5 877,957 + EFB2_00855 0.46 -0.6 877,957 + EFB2_00855 0.46 +0.5 877,958 - EFB2_00855 0.46 -1.7 877,958 - EFB2_00855 0.46 +3.7 877,959 + EFB2_00855 0.47 -0.5 877,959 + EFB2_00855 0.47 +0.5 877,959 + EFB2_00855 0.47 +0.2 877,959 + EFB2_00855 0.47 +2.5 877,960 - EFB2_00855 0.47 -3.4 877,960 - EFB2_00855 0.47 +1.9 877,960 - EFB2_00855 0.47 +1.6 877,961 + EFB2_00855 0.47 -1.2 877,961 + EFB2_00855 0.47 +0.6 877,961 + EFB2_00855 0.47 +0.4 877,962 - EFB2_00855 0.47 -1.2 877,962 - EFB2_00855 0.47 -0.9 877,962 - EFB2_00855 0.47 -0.0 877,962 - EFB2_00855 0.47 -1.7 877,962 - EFB2_00855 0.47 +1.0 877,968 + EFB2_00855 0.48 -0.5 877,969 - EFB2_00855 0.48 -0.6 877,974 + EFB2_00855 0.49 -1.1 877,974 + EFB2_00855 0.49 -3.0 877,975 - EFB2_00855 0.49 -2.6 878,072 + EFB2_00855 0.61 -1.3 878,073 - EFB2_00855 0.61 -0.9 878,075 + EFB2_00855 0.62 -1.5 878,075 + EFB2_00855 0.62 -1.3 878,076 - EFB2_00855 0.62 -0.3 878,091 + EFB2_00855 0.64 -1.6 878,126 + EFB2_00855 0.68 +0.6 878,192 - EFB2_00855 0.77 -0.4 878,192 - EFB2_00855 0.77 -1.0 878,200 + EFB2_00855 0.78 -0.1 878,200 + EFB2_00855 0.78 +0.5 878,200 + EFB2_00855 0.78 -0.8 878,200 + EFB2_00855 0.78 -1.1 878,200 + EFB2_00855 0.78 +0.7 878,200 + EFB2_00855 0.78 -0.0 878,200 + EFB2_00855 0.78 -0.1 878,200 + EFB2_00855 0.78 -1.1 878,201 - EFB2_00855 0.78 -0.5 878,201 - EFB2_00855 0.78 -1.3 878,201 - EFB2_00855 0.78 -1.2 878,201 - EFB2_00855 0.78 +1.1 878,201 - EFB2_00855 0.78 +1.0 878,201 - EFB2_00855 0.78 -1.4 878,204 + EFB2_00855 0.78 -0.5 878,204 + EFB2_00855 0.78 +0.1 878,204 + EFB2_00855 0.78 -1.5 878,204 + EFB2_00855 0.78 +0.1 878,204 + EFB2_00855 0.78 -0.2 878,204 + EFB2_00855 0.78 +1.2 878,205 - EFB2_00855 0.78 -0.7 878,205 - EFB2_00855 0.78 -3.7 878,219 + EFB2_00855 0.80 -2.2 878,231 + EFB2_00855 0.82 -0.5 878,231 + EFB2_00855 0.82 +0.8 878,231 + EFB2_00855 0.82 +0.5 878,231 + EFB2_00855 0.82 -3.5 878,232 - EFB2_00855 0.82 -1.0 878,232 - EFB2_00855 0.82 -1.6 878,237 + EFB2_00855 0.82 +0.2 878,238 - EFB2_00855 0.82 -3.2 878,238 - EFB2_00855 0.82 +2.0 878,253 + EFB2_00855 0.84 +1.0 878,253 + EFB2_00855 0.84 -1.0 878,253 + EFB2_00855 0.84 +0.5 878,254 - EFB2_00855 0.85 +0.8 878,254 - EFB2_00855 0.85 +0.2 878,263 + EFB2_00855 0.86 +0.2 878,263 + EFB2_00855 0.86 -1.6 878,263 + EFB2_00855 0.86 -0.2 878,263 + EFB2_00855 0.86 -2.6 878,263 + EFB2_00855 0.86 +1.3 878,263 + EFB2_00855 0.86 +0.3 878,263 + EFB2_00855 0.86 +0.2 878,263 + EFB2_00855 0.86 -1.0 878,264 - EFB2_00855 0.86 -0.9 878,264 - EFB2_00855 0.86 -2.1 878,264 - EFB2_00855 0.86 -1.7 878,266 - EFB2_00855 0.86 -1.1 878,266 - EFB2_00855 0.86 -0.4 878,290 + EFB2_00855 0.89 -1.0 878,290 + EFB2_00855 0.89 +1.4 878,290 + EFB2_00855 0.89 -0.7 878,290 + EFB2_00855 0.89 -2.0 878,338 + -0.9 878,338 + -1.6 878,339 - -0.5 878,339 - +0.4 878,375 + -0.3 878,375 + -2.1 878,375 + -4.7 878,375 + -2.4 878,376 - -2.6 878,376 - +0.6 878,376 - -1.6 878,401 - -2.7 878,424 + -0.7 878,424 + -3.0 878,425 - -0.0 878,425 - +0.8 878,425 - -0.6 878,425 - -1.7 878,425 - -0.6 878,440 + EFB2_00856 0.10 -2.1 878,478 - EFB2_00856 0.16 -2.9 878,499 - EFB2_00856 0.19 -0.7 878,562 - EFB2_00856 0.29 +0.0 878,572 + EFB2_00856 0.30 -1.9 878,573 - EFB2_00856 0.30 +0.1 878,650 + EFB2_00856 0.42 -0.5 878,650 + EFB2_00856 0.42 -1.6 878,653 - EFB2_00856 0.42 -1.0 878,715 - EFB2_00856 0.51 -1.5 878,715 - EFB2_00856 0.51 -2.6 878,718 + EFB2_00856 0.52 -2.0 878,719 - EFB2_00856 0.52 -0.3 878,754 - EFB2_00856 0.57 +1.4 878,779 + EFB2_00856 0.61 -0.4 878,793 - EFB2_00856 0.63 -1.1 878,802 + EFB2_00856 0.64 -0.5 878,805 + EFB2_00856 0.65 +0.3 878,805 + EFB2_00856 0.65 -0.6 878,806 - EFB2_00856 0.65 -3.8 878,806 - EFB2_00856 0.65 +1.7 878,806 - EFB2_00856 0.65 -1.1 878,807 + EFB2_00856 0.65 +0.0 878,808 - EFB2_00856 0.65 -0.8 878,821 + EFB2_00856 0.67 -1.8 878,951 - EFB2_00856 0.86 -1.3 878,954 + EFB2_00856 0.87 -2.7 879,088 - +1.3 879,096 + EFB2_00857 0.11 +1.3 879,097 - EFB2_00857 0.11 -2.4 879,105 + EFB2_00857 0.13 +0.2 879,110 - EFB2_00857 0.14 -0.9 879,110 - EFB2_00857 0.14 -1.3 879,295 + EFB2_00857 0.61 +0.5 879,316 + EFB2_00857 0.66 +2.8 879,370 - EFB2_00857 0.80 +1.8 879,421 - -1.4 879,537 + -0.4 879,541 - +0.8 879,541 - +0.8 879,641 + EFB2_00858 0.14 -0.3 879,677 + EFB2_00858 0.17 -2.5 879,677 + EFB2_00858 0.17 +3.7 879,678 - EFB2_00858 0.17 -0.1 879,678 - EFB2_00858 0.17 +1.5 879,679 + EFB2_00858 0.17 +0.9 879,679 + EFB2_00858 0.17 -0.9 879,679 + EFB2_00858 0.17 -0.7 879,679 + EFB2_00858 0.17 +0.6 879,680 - EFB2_00858 0.17 -2.1 879,680 - EFB2_00858 0.17 -0.1 879,681 + EFB2_00858 0.18 +2.5 879,682 - EFB2_00858 0.18 +0.5 879,718 - EFB2_00858 0.21 -0.7 879,731 - EFB2_00858 0.22 -0.9 879,740 + EFB2_00858 0.22 -0.1 879,798 + EFB2_00858 0.27 +1.6 879,802 + EFB2_00858 0.27 +1.3 879,802 + EFB2_00858 0.27 -2.1 879,889 - EFB2_00858 0.34 +0.9 879,917 + EFB2_00858 0.37 -2.4 879,925 + EFB2_00858 0.37 -0.4 879,928 - EFB2_00858 0.38 -0.3 879,942 - EFB2_00858 0.39 -0.0 879,964 - EFB2_00858 0.40 +1.8 879,987 + EFB2_00858 0.42 +0.1 879,987 + EFB2_00858 0.42 -1.1 879,987 + EFB2_00858 0.42 -1.6 879,987 + EFB2_00858 0.42 -2.3 879,987 + EFB2_00858 0.42 +1.0 879,988 - EFB2_00858 0.42 +2.0 879,989 + EFB2_00858 0.42 +0.1 879,989 + EFB2_00858 0.42 -0.7 879,990 - EFB2_00858 0.43 -3.1
Or see this region's nucleotide sequence